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Also known as: 136949-58-1, Xenetix, 182ech14uh, 1-n,3-n-bis(2,3-dihydroxypropyl)-5-[[3-hydroxy-2-(hydroxymethyl)propanoyl]amino]-2,4,6-triiodo-1-n,3-n-dimethylbenzene-1,3-dicarboxamide, N,n'-bis(2,3-dihydroxypropyl)-5-(2-(hydroxymethyl)hydracrylamido)-2,4,6-triiodo-n,n'-dimethylisophthalamide, Chebi:31701
Molecular Formula
C20H28I3N3O9
Molecular Weight
835.2  g/mol
InChI Key
YLPBXIKWXNRACS-UHFFFAOYSA-N
FDA UNII
182ECH14UH

Iobitridol
Iobitridol is a water-soluble, tri-iodinated, non-ionic monomeric benzoate derivative and contrast medium used in diagnostic radiography. Upon administration, iobitridol is distributed through the vascular system and interstitial space. Like other organic iodine compounds, this agent blocks x-rays and appears opaque on x-ray film thus, enhancing the visibility of body parts containing this agent. Iobitridol is rapidly removed by the kidneys in an unchanged form, and in cases of renal failure, heterotropic excretion occurs via the biliary route.
1 2D Structure

Iobitridol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-N,3-N-bis(2,3-dihydroxypropyl)-5-[[3-hydroxy-2-(hydroxymethyl)propanoyl]amino]-2,4,6-triiodo-1-N,3-N-dimethylbenzene-1,3-dicarboxamide
2.1.2 InChI
InChI=1S/C20H28I3N3O9/c1-25(3-10(31)7-29)19(34)12-14(21)13(20(35)26(2)4-11(32)8-30)16(23)17(15(12)22)24-18(33)9(5-27)6-28/h9-11,27-32H,3-8H2,1-2H3,(H,24,33)
2.1.3 InChI Key
YLPBXIKWXNRACS-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN(CC(CO)O)C(=O)C1=C(C(=C(C(=C1I)NC(=O)C(CO)CO)I)C(=O)N(C)CC(CO)O)I
2.2 Other Identifiers
2.2.1 UNII
182ECH14UH
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 5-(3-hydroxy-2-hydroxymethylpropionamido)-n,n'-dimethyl-n,n'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide

2. Xenetix

2.3.2 Depositor-Supplied Synonyms

1. 136949-58-1

2. Xenetix

3. 182ech14uh

4. 1-n,3-n-bis(2,3-dihydroxypropyl)-5-[[3-hydroxy-2-(hydroxymethyl)propanoyl]amino]-2,4,6-triiodo-1-n,3-n-dimethylbenzene-1,3-dicarboxamide

5. N,n'-bis(2,3-dihydroxypropyl)-5-(2-(hydroxymethyl)hydracrylamido)-2,4,6-triiodo-n,n'-dimethylisophthalamide

6. Chebi:31701

7. 1,3-benzenedicarboxamide, N,n'-bis(2,3-dihydroxypropyl)-5-((5-hydroxy-2-(hydroxymethyl)-1-oxopropyl)amino)-2,4,6-triiodo-n,n'-dimethyl-

8. Iobitridol [inn]

9. Xenetix 300

10. Iobitridol [inn:ban]

11. Unii-182ech14uh

12. Iobitridol [mi]

13. Iobitridol (jan/inn)

14. Iobitridol [jan]

15. Iobitridol [mart.]

16. Iobitridol [who-dd]

17. Schembl23057

18. Chembl2107212

19. Dtxsid90869865

20. Db12407

21. Ncgc00532516-01

22. 5-(3-hydroxy-2-hydroxymethylpropionamido)-n,n'-dimethyl-n,n'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide

23. Ft-0627244

24. D01181

25. J-006941

26. Q6062197

27. 1,3-benzenedicarboxamide, N1,n3-bis(2,3-dihydroxypropyl)-5-((3-hydroxy-2-(hydroxymethyl)-1-oxopropyl)amino)-2,4,6-triiodo-n1,n3-dimethyl-

28. 5-(3-hydroxy-2-(hydroxymethyl)-propionamido)-n,n'-dimethyl-n,n'-bis-(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide

29. 5-[3-hydroxy-2-(hydroxymethyl)-propionamido]-n-n -dimethyl-n-n -bis-(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide

30. N,n'-bis(2,3-dihydroxypropyl)-5-((3-hydroxy-2-(hydroxymethyl)-1-oxopropyl)amino)-2,4,6-triiodo-n,n'-dimethyl-1,3-benzenedicarboxamide

31. N,n'-bis(2,3-dihydroxypropyl)-5-{[3-hydroxy-2-(hydroxymethyl)propanoyl]amino}-2,4,6-triiodo-n,n'-dimethylbenzene-1,3-dicarboxamide

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 835.2 g/mol
Molecular Formula C20H28I3N3O9
XLogP3-3
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count9
Rotatable Bond Count12
Exact Mass834.8960 g/mol
Monoisotopic Mass834.8960 g/mol
Topological Polar Surface Area191 Ų
Heavy Atom Count35
Formal Charge0
Complexity675
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Contrast Media

Substances used to allow enhanced visualization of tissues. (See all compounds classified as Contrast Media.)


4.2 ATC Code

V08AB11

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355


V - Various

V08 - Contrast media

V08A - X-ray contrast media, iodinated

V08AB - Watersoluble, nephrotropic, low osmolar x-ray contrast media

V08AB11 - Iobitridol


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ABOUT THIS PAGE

Iobitridol Manufacturers

A Iobitridol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Iobitridol, including repackagers and relabelers. The FDA regulates Iobitridol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Iobitridol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Iobitridol manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Iobitridol Suppliers

A Iobitridol supplier is an individual or a company that provides Iobitridol active pharmaceutical ingredient (API) or Iobitridol finished formulations upon request. The Iobitridol suppliers may include Iobitridol API manufacturers, exporters, distributors and traders.

click here to find a list of Iobitridol suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Iobitridol GMP

Iobitridol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Iobitridol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Iobitridol GMP manufacturer or Iobitridol GMP API supplier for your needs.

Iobitridol CoA

A Iobitridol CoA (Certificate of Analysis) is a formal document that attests to Iobitridol's compliance with Iobitridol specifications and serves as a tool for batch-level quality control.

Iobitridol CoA mostly includes findings from lab analyses of a specific batch. For each Iobitridol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Iobitridol may be tested according to a variety of international standards, such as European Pharmacopoeia (Iobitridol EP), Iobitridol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Iobitridol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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