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Chemistry

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Also known as: 66108-95-0, Omnipaque, Nycodenz, Exypaque, Iohexolum, Omnipaque 240
Molecular Formula
C19H26I3N3O9
Molecular Weight
821.1  g/mol
InChI Key
NTHXOOBQLCIOLC-UHFFFAOYSA-N
FDA UNII
4419T9MX03

Iohexol
An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Iohexol is a Radiographic Contrast Agent. The mechanism of action of iohexol is as a X-Ray Contrast Activity.
1 2D Structure

Iohexol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-[acetyl(2,3-dihydroxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
2.1.2 InChI
InChI=1S/C19H26I3N3O9/c1-8(29)25(4-11(32)7-28)17-15(21)12(18(33)23-2-9(30)5-26)14(20)13(16(17)22)19(34)24-3-10(31)6-27/h9-11,26-28,30-32H,2-7H2,1H3,(H,23,33)(H,24,34)
2.1.3 InChI Key
NTHXOOBQLCIOLC-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
2.2 Other Identifiers
2.2.1 UNII
4419T9MX03
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Compound 545

2. Exypaque

3. Iohexol 350

4. Nycodenz

5. Omnipaque

2.3.2 Depositor-Supplied Synonyms

1. 66108-95-0

2. Omnipaque

3. Nycodenz

4. Exypaque

5. Iohexolum

6. Omnipaque 240

7. Omnipaque 70

8. Omnipaque 140

9. Omnipaque 180

10. Omnipaque 210

11. Omnipaque 300

12. Omnipaque 350

13. Win 39424

14. Oraltag

15. Win-39424

16. Chebi:31709

17. N,n'-bis(2,3-dihydroxypropyl)-5-(n-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamide

18. 5-[acetyl(2,3-dihydroxypropyl)amino]-1-n,3-n-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide

19. 5-[acetyl(2,3-dihydroxypropyl)amino]-n,n'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide

20. N1,n3-bis(2,3-dihydroxypropyl)-5-(n-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamide

21. 4419t9mx03

22. Nsc-759636

23. Ncgc00166000-01

24. Dsstox_cid_3157

25. 5-(n-2,3-dihydroxypropylacetamido)-2,4,6-triiodo-n,n'-bis(2,3-dihydroxypropyl)isophthalamide

26. Dsstox_rid_76895

27. Dsstox_gsid_23157

28. 1,3-benzenedicarboxamide, 5-(acetyl(2,3-dihydroxypropyl)amino)-n,n'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-

29. Histodenz

30. Iohexolum [inn-latin]

31. 1,3-benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-n1,n3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-

32. 5-[acetyl(2,3-dihydroxypropyl)amino]-n,n'-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide

33. 5-[n-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodo-n,n'-bis(2,3-dihydroxypropyl)isophthalamide

34. Smr000857075

35. Einecs 266-164-2

36. Brn 2406632

37. Unii-4419t9mx03

38. Omnipaque (tn)

39. 1,3-benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-n,n'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-

40. N,n'-bis(2,3-dihydroxypropyl)-5-[n-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodoisophthalamide

41. Prestwick_802

42. Cas-66108-95-0

43. Iohexol [usan:usp:inn:ban:jan]

44. Iohexol [vandf]

45. Iohexol [usan]

46. Iohexol [inn]

47. Iohexol [jan]

48. Iohexol [mi]

49. Iohexol [mart.]

50. Prestwick0_000512

51. Prestwick1_000512

52. Prestwick2_000512

53. Prestwick3_000512

54. Iohexol [usp-rs]

55. Iohexol [who-dd]

56. Iohexol [who-ip]

57. Nycodenz;omnipaque;exypaque

58. Ec 266-164-2

59. Iohexol, Analytical Standard

60. Schembl26501

61. Bspbio_000463

62. Mls001332585

63. Mls001332586

64. Mls002153854

65. Iohexol (jp17/usp/inn)

66. Iohexol [ep Impurity]

67. Iohexol [orange Book]

68. Spbio_002384

69. Iohexol [ep Monograph]

70. Bpbio1_000511

71. Iohexol [usp Monograph]

72. Chembl1200455

73. Dtxsid6023157

74. Bcbcmap01_000051

75. Iohexolum [who-ip Latin]

76. Hms1569h05

77. Hms2096h05

78. Hms2235d07

79. Hms3369o04

80. Hms3713h05

81. Albb-028959

82. Amy21804

83. Bcp31800

84. Hy-b0594

85. Tox21_112286

86. Bdbm50247977

87. Iohexol (mixture Of Isomers)

88. Mfcd00077732

89. S4531

90. Akos015895399

91. Tox21_112286_1

92. Ac-1934

93. Ccg-220512

94. Db01362

95. Nsc 759636

96. Smp1_000152

97. Ncgc00166000-02

98. Ncgc00166000-04

99. As-12699

100. Ft-0627276

101. I0903

102. D01817

103. D91214

104. Histodenz(tm), Nonionic Density Gradient Medium

105. 108i950

106. A835339

107. Q410683

108. Sr-01000838892

109. Sr-01000838892-2

110. Iohexol, European Pharmacopoeia (ep) Reference Standard

111. Iohexol, United States Pharmacopeia (usp) Reference Standard

112. 5-(n-dhp-acetamido)-2,4,6-triiodo-n,n'-b Is-dhp-isophthalami

113. Iohexol, Pharmaceutical Secondary Standard; Certified Reference Material

114. Iohexol For Peak Identification, European Pharmacopoeia (ep) Reference Standard

115. 1,3-benzenedicarboxamide, 5-(acetyl(2,3-dihydroxypropyl)amino)-n,n'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo

116. 1-n,3-n-bis(2,3-dihydroxypropyl)-5-[n-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide

117. 5-[acetyl(2,3-dihydroxypropyl)amino]-n1,n3-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide

118. N1,n3-bis(2,3-dihydroxypropyl)-5-[n-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide

119. N1,n3-bis[2,3-bis(oxidanyl)propyl]-5-[2,3-bis(oxidanyl)propyl-ethanoyl-amino]-2,4,6-tris(iodanyl)benzene-1,3-dicarboxamide

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 821.1 g/mol
Molecular Formula C19H26I3N3O9
XLogP3-3
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count9
Rotatable Bond Count12
Exact Mass820.8803 g/mol
Monoisotopic Mass820.8803 g/mol
Topological Polar Surface Area200 Ų
Heavy Atom Count34
Formal Charge0
Complexity653
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count3
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NameOmnipaque 180
PubMed HealthIohexol (Injection)
Drug ClassesRadiological Non-Ionic Contrast Media
Active IngredientIohexol
Dosage FormSolution
RouteInjection, oral, rectal
Strength38.8%
Market StatusPrescription
CompanyGe Healthcare

2 of 4  
Drug NameOmnipaque 240
Active IngredientIohexol
Dosage FormSolution
RouteInjection, oral, rectal
Strength51.8%
Market StatusPrescription
CompanyGe Healthcare

3 of 4  
Drug NameOmnipaque 180
PubMed HealthIohexol (Injection)
Drug ClassesRadiological Non-Ionic Contrast Media
Active IngredientIohexol
Dosage FormSolution
RouteInjection, oral, rectal
Strength38.8%
Market StatusPrescription
CompanyGe Healthcare

4 of 4  
Drug NameOmnipaque 240
Active IngredientIohexol
Dosage FormSolution
RouteInjection, oral, rectal
Strength51.8%
Market StatusPrescription
CompanyGe Healthcare

4.2 Drug Indication

Iohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.


5 Pharmacology and Biochemistry
5.1 Pharmacology

Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.


5.2 MeSH Pharmacological Classification

Contrast Media

Substances used to allow enhanced visualization of tissues. (See all compounds classified as Contrast Media.)


5.3 FDA Pharmacological Classification
5.3.1 Active Moiety
IOHEXOL
5.3.2 FDA UNII
4419T9MX03
5.3.3 Pharmacological Classes
X-Ray Contrast Activity [MoA]; Radiographic Contrast Agent [EPC]
5.4 ATC Code

V08AB02

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355


V - Various

V08 - Contrast media

V08A - X-ray contrast media, iodinated

V08AB - Watersoluble, nephrotropic, low osmolar x-ray contrast media

V08AB02 - Iohexol


5.5 Absorption, Distribution and Excretion

Absorption

Small amounts are absorbed through the bladder via intravesical instillation. Following intrauterine instillation, the majority of the medium within the uterine cavity is discharged into the vagina immediately upon termination of procedure. However, any medium retained in the uterine or peritoneal cavity is absorbed systemically within 60 minutes. May not be absorbed for up to 24 hours if tubes are obstructed and dilated.


Route of Elimination

Iohexol is absorbed from cerebrospinal fluid (CSF) into the bloodstream and is eliminated by renal excretion. No significant metabolism, deiodination, or biotransformation occurs.


Volume of Distribution

350-849 mL/kg


Clearance

109 mL/min [Adult patients receiving 16-18 ml of iohexol (180 mgI/mL) by lumbar intrathecal injection]


5.6 Biological Half-Life

Intrathecal half-life is 3.4 hours (mean). Intravascular is approximately 2 hours (with normal renal function).


5.7 Mechanism of Action

Organic iodine compounds block x-rays as they pass through the body, thereby allowing body structures containing iodine to be delineated in contrast to those structures that do not contain iodine. The degree of opacity produced by these compounds is directly proportional to the total amount (concentration and volume) of the iodinated contrast agent in the path of the x-rays. After intrathecal administration into the subarachnoid space, diffusion of iohexol in the CSF allows the visualization of the subarachnoid spaces of the head and spinal canal. After intravascular administration, iohexol makes opaque those vessels in its path of flow, allowing visualization of the internal structures until significant hemodilution occurs.


USDMF

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DMF Review : Complete

Rev. Date : 2023-05-03

Pay. Date : 2023-03-23

DMF Number : 38195

Submission : 2023-03-20

Status : Active

Type : II

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Submission : 2013-01-24

Status : Inactive

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Submission : 2009-02-23

Status : Inactive

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DMF Review : Complete

Rev. Date : 2021-10-13

Pay. Date : 2021-09-14

DMF Number : 36038

Submission : 2021-09-15

Status : Active

Type : II

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Iohexol

Registration Number : 305MF10075

Registrant's Address : No. 01 Pengze Nine road, Jishan Industrial Park, Pengze County, Jiujiang City, Jiangx...

Initial Date of Registration : 2023-07-05

Latest Date of Registration : 2023-07-05

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Omnipark

Registration Number : 217MF10959

Registrant's Address : Lindesnesveien 208, 4521 Lindesnes, Norway

Initial Date of Registration : 2005-11-14

Latest Date of Registration : 2023-02-02

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Iohexol

Registration Number : 304MF10054

Registrant's Address : No. 1 Starry Road of Xianju Modern Industrial Centralization Zone, Xianju, Zhejiang, ...

Initial Date of Registration : 2022-03-16

Latest Date of Registration : 2022-03-16

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Iohexol

Registration Number : 219MF10263

Registrant's Address : Zhejiang Province Chemical and Medical Materials Base, Linhai Park

Initial Date of Registration : 2007-08-16

Latest Date of Registration : 2014-07-01

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Iohexol

Registration Number : 227MF10106

Registrant's Address : Zhejiang Province Chemical and Medical Materials Base, Linhai Park

Initial Date of Registration : 2015-04-09

Latest Date of Registration : 2015-04-09

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Iohexol

Registrant Name : Parmarine Co., Ltd.

Registration Date : 2022-05-17

Registration Number : 20220517-210-J-1297

Manufacturer Name : Divi's Laboratories Ltd.

Manufacturer Address : Unit-2, Chippada Village, Annavaram Post – 531 162, Bheemunipatnam Mandal, Visakhap...

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Iohexol

Registrant Name : Korea Biochem Pharmaceutical Co., Ltd.

Registration Date : 2020-07-17

Registration Number : 20200107-210-J-363(2)

Manufacturer Name : GE Healthcare AS

Manufacturer Address : Lindesnesveien 208, Lindesnes, NO-4521, Norway

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Registrant Name : Palm East Co., Ltd.

Registration Date : 2020-04-02

Registration Number : 20200107-210-J-363(1)

Manufacturer Name : GE Healthcare AS

Manufacturer Address : Lindesnesveien 208, Lindesnes, NO-4521, Norway

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Iohexol

Registrant Name : GE Healthcare AS Korea Branch

Registration Date : 2020-01-07

Registration Number : 20200107-210-J-363

Manufacturer Name : GE Healthcare AS, Lindesnes ...

Manufacturer Address : Lindesnesveien 208, NO 4521, Lindesnes, Norway

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Iohexol

Registrant Name : Pharmapia Co., Ltd.

Registration Date : 2021-02-15

Registration Number : 20210215-210-J-472

Manufacturer Name : Zhejiang Haizhou Pharmaceuti...

Manufacturer Address : Yanhai Industrial Zone, Linhai City, Zhejiang Province, China

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Registrant Name : Ace Biopharm Co., Ltd.

Registration Date : 2023-09-11

Registration Number : 20230911-210-J-1543

Manufacturer Name : Zhejiang Hichi Pharmaceutica...

Manufacturer Address : No.36 Changshun Road, Bingang Industrial Zone, Shamen Town, Yuhuan, Zhejiang, China

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Registrant Name : Korea Pavise Pharmaceutical Co., Ltd.

Registration Date : 2019-10-30

Registration Number : 20180814-210-J-252(5)

Manufacturer Name : Zhejiang Taizhou Hisyn Pharm...

Manufacturer Address : Chemical and Medical Raw Materials Base Linhai Park, Zhejiang Province China

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Registrant Name : Central Medical Service Co., Ltd.

Registration Date : 2024-09-26

Registration Number : 20210215-210-J-472(1)

Manufacturer Name : Zhejiang Haizhou Pharmaceuti...

Manufacturer Address : Yanhai Industrial Zone, Linhai City, Zhejiang Province, China

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Registrant Name : Korea Biochem Pharmaceutical Co., Ltd.

Registration Date : 2022-04-27

Registration Number : 20210308-210-J-719(1)

Manufacturer Name : Zhejiang Starry Pharmaceutic...

Manufacturer Address : No.1 Starry Road, Xianju Modern Industrial Centralization Zone, Xianju County, Zhejia...

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Registrant Name : Encomac Co., Ltd.

Registration Date : 2022-07-15

Registration Number : 20210308-210-J-719(2)

Manufacturer Name : Zhejiang Starry Pharmaceutic...

Manufacturer Address : No.1 Starry Road, Xianju Modern Industrial Centralization Zone, Xianju County, Zhejia...

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IOHEXOL

NDC Package Code : 62331-066

Start Marketing Date : 2022-07-04

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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NDC Package Code : 65072-0801

Start Marketing Date : 2020-07-10

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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NDC Package Code : 43228-100

Start Marketing Date : 1985-12-26

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

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About the Company : Biophore, founded in 2007, has established itself as a reliable partner in the development and manufacturing of niche and complex pharmaceutical products. With 4 USFDA and EU-appro...

Biophore, founded in 2007, has established itself as a reliable partner in the development and manufacturing of niche and complex pharmaceutical products. With 4 USFDA and EU-approved API manufacturing facilities, a dedicated intermediate facility, and a R&D laboratory housing 400 scientists, Biophore has positioned itself as a global leader among API companies. It consistently ranks among the top 10 US DMF filers and has obtained over 150 patents worldwide in process and polymorph areas. Biophore's facilities have an impressive track record of successful audits by regulatory bodies such as USFDA, EMEA, ANVISA, COFEPRIS, and WHO GMP.
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About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.
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Virtual BoothRochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

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Iohexol

About the Company : Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quali...

Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quality ingredients manufactured in China. Headquartered in the Hauppauge, New York, Rochem has 16 offices spread across the globe to cater to the needs of its customers. Rochem’s operations are fully cGMP compliant and has been audited by the USFDA as well as several multinational organizations. It also trains and audits its partners to ensure all of their technologies and systems are FDA-compliant.
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About the Company : Arde’s Laboratories Pvt Ltd. is a specialty pharmaceutical company that is engaged in the development, manufacture and marketing of generic pharmaceutical drugs. Arde’s is buil...

Arde’s Laboratories Pvt Ltd. is a specialty pharmaceutical company that is engaged in the development, manufacture and marketing of generic pharmaceutical drugs. Arde’s is built by a team of technocrats with a colossal expertise in pharmaceutical world. Arde’s team are all recognized names in the pharmaceutical industry whose capabilities have evolved over the years globally. Arde’s aims in developing affordable quality niche generic molecules with an expertise in development, including advanced scientific research, process development, patent analysis, regulatory compliance and market competition analysis.
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Iohexol

About the Company : Brother Enterprises Holding Co., Ltd. was founded in 1991 and is headquartered in Haining City, Zhejiang Province, China. With over 30 years of experience, Brother Enterprises has ...

Brother Enterprises Holding Co., Ltd. was founded in 1991 and is headquartered in Haining City, Zhejiang Province, China. With over 30 years of experience, Brother Enterprises has grown into an international chemical group, covering four business divisions – leather chemicals, vitamins, spices, and active pharmaceutical ingredients. There are also several wholly owned subsidiaries. Brother Enterprises has four manufacturing plants: three in China (Zhejiang Province, Jiangsu Province, and Jiangxi Province) and one in Newcastle, South Africa.
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06

AusBiotech 2024
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AusBiotech 2024
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Iohexol

About the Company : Divi's Laboratories Limited is a leading independent contract manufacturer of Active Pharmaceutical Ingredients and registered intermediates. We custom / exclusively manufacture fo...

Divi's Laboratories Limited is a leading independent contract manufacturer of Active Pharmaceutical Ingredients and registered intermediates. We custom / exclusively manufacture for several Big Pharma companies under full cGMP. Customers regularly audit our facilities in areas of quality, EHS, business continuity etc. Unmatched Infrastructure:2 manufacturing sites. Both sites were successfully US-FDA Inspected No of DMFs 373 Pilot Plants30 Production Buildings39 Pharma Suites944 Reactors - 250 L to 30 KLTotal Capacity - 6676 M34 R&D Centers325 Scientists.
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07

AusBiotech 2024
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AusBiotech 2024
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Iohexol

About the Company : As an EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979 as Calcium Ind...

As an EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979 as Calcium India. Today, Global Calcium represents the true hallmark of quality when it comes to pharmaceutical products. Global Calcium is backed by an excellent management team comprising of industry specialists, technocrats, entrepreneurs and business specialists bringing in strong domain expertise in fields such as investment banking, to consulting to behind the scenes pure sciences.
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08

Grupo Juste

Spain
AusBiotech 2024
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Grupo Juste

Spain
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AusBiotech 2024
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Iohexol

About the Company : The Juste Group is the result of a merger of two companies: Justesa Imagen, centered on Chemicals, and Juste Farma, a pharmaceutical company. It has completed 100 years of growth, ...

The Juste Group is the result of a merger of two companies: Justesa Imagen, centered on Chemicals, and Juste Farma, a pharmaceutical company. It has completed 100 years of growth, continuously improving our capacity for developing, producing, and distributing active pharmaceutical ingredients and medicines. We research, develop, produce, and distribute pharmaceuticals and active ingredients for the pharmaceutical industry in Europe, the U.S.A. and Canada, Central and South America, the Middle East, and India.
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09

AusBiotech 2024
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AusBiotech 2024
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Iohexol

About the Company : HENGDIAN GROUP was established in 1975, till now it has become a transnational,conglomerate group and been one of the largest private-owned enterprises in China. The Pharmaceutical...

HENGDIAN GROUP was established in 1975, till now it has become a transnational,conglomerate group and been one of the largest private-owned enterprises in China. The Pharmaceutical & Chemical division has 3 sub-companies with over 3,000 employees of which over 30% are technicians; This division is mainly producing APIs, Agrochemical and Dyestuffs with related intermediates as well as other special chemicals. The group also focuses on CONTRACT MANUFACTURE service under GMP and confidential agreement with our clients.
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10

Hetero Drugs

India
AusBiotech 2024
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Hetero Drugs

India
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AusBiotech 2024
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Iohexol

About the Company : Hetero is a research based global pharmaceutical company focused on development, manufacturing and marketing of Active Pharmaceutical Ingredients (APIs), Intermediate Chemicals & F...

Hetero is a research based global pharmaceutical company focused on development, manufacturing and marketing of Active Pharmaceutical Ingredients (APIs), Intermediate Chemicals & Finished Dosages. Ever since its establishment in 1993, Hetero showed a tradition of excellence and deep sense of commitment in developing cost effective processes to offer wide range of affordable drugs. Hetero is building on the strengths of vertical integration in discovery research, process chemistry, API manufacturing, formulation development and commercialization.
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LTD","customerCountry":"INDIA","quantity":"54.00","actualQuantity":"54","unit":"KGS","unitRateFc":"100.8","totalValueFC":"5511.8","currency":"USD","unitRateINR":"8553.7","date":"09-Sep-2024","totalValueINR":"461898.45","totalValueInUsd":"5511.8","indian_port":"Hyderabad Air","hs_no":"29242990","bill_no":"5505266","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"NO.36 CHANGSHUNROAD BINGANGINDUSTR IAL ZONE SDNF China","customerAddress":"101, SITARAM MANSION,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725906600,"product":"IOHEXOL USP","address":"2NF FLOOR,BUILDING A,","city":"ANDHERI[W],MUMBAI,","supplier":"JIANGXI BROTHER PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"GUFIC BIOSCIENCES","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"100.5","totalValueFC":"30545.3","currency":"USD","unitRateINR":"8532.5","date":"10-Sep-2024","totalValueINR":"2559735","totalValueInUsd":"30545.3","indian_port":"Bombay Air","hs_no":"29242990","bill_no":"5524865","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"CO., LTDJISHAN INDUSTRIAL PARK,PENG ZE COUNTY JIUJIANG CITY,JIANGXI PRO VINCE CHINA CHINA","customerAddress":"2NF FLOOR,BUILDING A,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726425000,"product":"IOHEXOL USP","address":"301, PANCH SAGAR, CHITANVIS LAYOUT,","city":"NAGPUR (M.S.)","supplier":"JIANGXI BROTHER PHARMACEUTICAL CO.,LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"GENETEK LIFESCIENCES PRIVATE ","customerCountry":"INDIA","quantity":"5000.00","actualQuantity":"5000","unit":"KGS","unitRateFc":"96","totalValueFC":"486801.9","currency":"USD","unitRateINR":"8158.9","date":"16-Sep-2024","totalValueINR":"40794590.91","totalValueInUsd":"486801.9","indian_port":"JNPT","hs_no":"29242990","bill_no":"5626859","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"JISHAN INDUSTRIAL PARK, PENGZE COUN TY, JIUJIANG CITY, JIANGXI PROVINCE SDNF China","customerAddress":"301, PANCH SAGAR, CHITANVIS LAYOUT,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727375400,"product":"IOHEXOL","address":"101, SITARAM MANSION,","city":"KAROL BAGH, NEW DELHI","supplier":"ZHEJIANG HISYN PHARMACEUTICAL CO., LTD.","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"JODAS EXPOIM PVT. LTD","customerCountry":"INDIA","quantity":"1475.00","actualQuantity":"1475","unit":"KGS","unitRateFc":"104.5","totalValueFC":"155606.7","currency":"USD","unitRateINR":"8840.7","date":"27-Sep-2024","totalValueINR":"13040032.5","totalValueInUsd":"155606.7","indian_port":"Hyderabad Air","hs_no":"29242990","bill_no":"5826068","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"CHEMICAL AND MEDICAL RAW MATERIALS BASE,LINHAI PARK SDNF China","customerAddress":"101, SITARAM MANSION,"}]
06-Mar-2021
27-Sep-2024
KGS
overview
Loading...

Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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INTERMEDIATES SUPPLIERS

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01

AusBiotech 2024
Not Confirmed
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AusBiotech 2024
Not Confirmed
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CAS Number : CAS-96-24-2

End Use API : Iohexol

About The Company : Blue Jet Healthcare is a global, science-driven pharmaceutical company specializing in collaboration, development, and manufacturing of advanced pharmaceutical ...

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02

AusBiotech 2024
Not Confirmed
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AusBiotech 2024
Not Confirmed
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CAS Number : CAS-616-30-8

End Use API : Iohexol

About The Company : Blue Jet Healthcare is a global, science-driven pharmaceutical company specializing in collaboration, development, and manufacturing of advanced pharmaceutical ...

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03

AusBiotech 2024
Not Confirmed
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AusBiotech 2024
Not Confirmed
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CAS Number : CAS-76801-93-9

End Use API : Iohexol

About The Company : Blue Jet Healthcare is a global, science-driven pharmaceutical company specializing in collaboration, development, and manufacturing of advanced pharmaceutical ...

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04

AusBiotech 2024
Not Confirmed
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AusBiotech 2024
Not Confirmed
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CAS Number : CAS-618-88-2

End Use API : Iohexol

About The Company : Blue Jet Healthcare is a global, science-driven pharmaceutical company specializing in collaboration, development, and manufacturing of advanced pharmaceutical ...

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05

AusBiotech 2024
Not Confirmed
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AusBiotech 2024
Not Confirmed
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CAS Number : CAS-13290-96-5

End Use API : Iohexol

About The Company : Blue Jet Healthcare is a global, science-driven pharmaceutical company specializing in collaboration, development, and manufacturing of advanced pharmaceutical ...

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06

AusBiotech 2024
Not Confirmed
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AusBiotech 2024
Not Confirmed
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CAS Number : CAS-618-88-2

End Use API : Iohexol

About The Company : Shreeneel Chemicals is dedicated to quality healthcare development and fostering a knowledgeable environment. The company was founded by Mr. Sanjay Tavethiya an...

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07

AusBiotech 2024
Not Confirmed
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AusBiotech 2024
Not Confirmed
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CAS Number : CAS-13290-96-5

End Use API : Iohexol

About The Company : Shreeneel Chemicals is dedicated to quality healthcare development and fostering a knowledgeable environment. The company was founded by Mr. Sanjay Tavethiya an...

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FDA Orange Book

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01

GE HEALTHCARE

United Kingdom
AusBiotech 2024
Not Confirmed
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GE HEALTHCARE

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

IOHEXOL

Brand Name : OMNIPAQUE 180

Dosage Form : SOLUTION;INJECTION, ORAL, RECTAL

Dosage Strength : 38.8%

Approval Date : 1985-12-26

Application Number : 18956

RX/OTC/DISCN : RX

RLD : Yes

TE Code :

blank

02

GE HEALTHCARE

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE HEALTHCARE

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

IOHEXOL

Brand Name : OMNIPAQUE 240

Dosage Form : SOLUTION;INJECTION, ORAL, RECTAL

Dosage Strength : 51.8%

Approval Date : 1985-12-26

Application Number : 18956

RX/OTC/DISCN : RX

RLD : Yes

TE Code :

blank

03

GE HEALTHCARE

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE HEALTHCARE

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

IOHEXOL

Brand Name : OMNIPAQUE 300

Dosage Form : SOLUTION;INJECTION, ORAL, RECTAL

Dosage Strength : 64.7%

Approval Date : 1985-12-26

Application Number : 18956

RX/OTC/DISCN : RX

RLD : Yes

TE Code :

blank

04

GE HEALTHCARE

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE HEALTHCARE

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

IOHEXOL

Brand Name : OMNIPAQUE 350

Dosage Form : SOLUTION;INJECTION, ORAL

Dosage Strength : 75.5%

Approval Date : 1985-12-26

Application Number : 18956

RX/OTC/DISCN : RX

RLD : Yes

TE Code :

blank

05

GE HEALTHCARE

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE HEALTHCARE

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

IOHEXOL

Brand Name : OMNIPAQUE 140

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 30.2%

Approval Date : 1988-11-30

Application Number : 18956

RX/OTC/DISCN : RX

RLD : Yes

TE Code :

blank

06

GE HEALTHCARE

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE HEALTHCARE

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

IOHEXOL

Brand Name : OMNIPAQUE 210

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 45.3%

Approval Date : 1989-06-30

Application Number : 18956

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

blank

07

GE HEALTHCARE

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE HEALTHCARE

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

IOHEXOL

Brand Name : OMNIPAQUE 70

Dosage Form : SOLUTION;URETHRAL

Dosage Strength : 15.1%

Approval Date : 1994-06-01

Application Number : 18956

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

blank

08

GE HEALTHCARE

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE HEALTHCARE

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

IOHEXOL

Brand Name : OMNIPAQUE 240

Dosage Form : SOLUTION;INJECTION, ORAL, RECTAL

Dosage Strength : 51.8%

Approval Date : 1995-10-24

Application Number : 20608

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

blank

09

GE HEALTHCARE

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE HEALTHCARE

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

IOHEXOL

Brand Name : OMNIPAQUE 300

Dosage Form : SOLUTION;INJECTION, ORAL, RECTAL

Dosage Strength : 64.7%

Approval Date : 1995-10-24

Application Number : 20608

RX/OTC/DISCN : RX

RLD : No

TE Code :

blank

10

GE HEALTHCARE

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE HEALTHCARE

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

IOHEXOL

Brand Name : OMNIPAQUE 350

Dosage Form : SOLUTION;INJECTION, ORAL

Dosage Strength : 75.5%

Approval Date : 1995-10-24

Application Number : 20608

RX/OTC/DISCN : RX

RLD : No

TE Code :

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South Africa

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01

GE Healthcare (Pty) Ltd

United Kingdom
AusBiotech 2024
Not Confirmed
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GE Healthcare (Pty) Ltd

United Kingdom
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AusBiotech 2024
Not Confirmed

Iohexol

Brand Name : Omnipaque 300Mg I/Ml (200Ml)

Dosage Form : INJ

Dosage Strength : 300mg/ml

Packaging : 200X1mg/ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

blank

02

GE Healthcare (Pty) Ltd

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE Healthcare (Pty) Ltd

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name : Omnipaque 300Mg I/Ml (500Ml)

Dosage Form : Inj

Dosage Strength : 300mg/ml

Packaging : 500X1mg/ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

blank

03

GE Healthcare (Pty) Ltd

United Kingdom
AusBiotech 2024
Not Confirmed
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GE Healthcare (Pty) Ltd

United Kingdom
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AusBiotech 2024
Not Confirmed

Iohexol

Brand Name : Omnipaque 350Mg I/Ml (200Ml)

Dosage Form : Inj

Dosage Strength : 350mg/ml

Packaging : 200X1mg/ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

blank

04

GE Healthcare (Pty) Ltd

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE Healthcare (Pty) Ltd

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name : Omnipaque 350Mg I/Ml (500Ml)

Dosage Form : Inj

Dosage Strength : 350mg/ml

Packaging : 500X1mg/ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

blank

05

GE Healthcare (Pty) Ltd

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE Healthcare (Pty) Ltd

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name : Omnipaque 300Mg I/Ml (100Ml)

Dosage Form : Inj

Dosage Strength : 300mg/ml

Packaging : 100X1mg/ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

blank

06

GE Healthcare (Pty) Ltd

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE Healthcare (Pty) Ltd

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name : Omnipaque 300Mg I/Ml (20Ml)

Dosage Form : Inj

Dosage Strength : 300mg/ml

Packaging : 20X1mg/ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

blank

07

GE Healthcare (Pty) Ltd

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE Healthcare (Pty) Ltd

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name : Omnipaque 300Mg I/Ml (50Ml)

Dosage Form : Inj

Dosage Strength : 300mg/ml

Packaging : 50X1mg/ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

blank

08

GE Healthcare (Pty) Ltd

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE Healthcare (Pty) Ltd

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name : Omnipaque 350Mg I/Ml (50Ml)

Dosage Form : Inj

Dosage Strength : 350mg/ml

Packaging : 50X1mg/ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

blank

09

GE Healthcare (Pty) Ltd

United Kingdom
AusBiotech 2024
Not Confirmed
arrow

GE Healthcare (Pty) Ltd

United Kingdom
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name : Omnipaque 350Mg I/Ml (100Ml)

Dosage Form : Inj

Dosage Strength : 350mg/ml

Packaging : 100X1mg/ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

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Listed Dossiers

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Iohexol

Brand Name :

Dosage Form : Injection

Dosage Strength : 240MG/ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Biophore

01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

Flag India
Digital Content Digital Content

Packaging :

Regulatory Info :

Iohexol

Dosage : Injection

Dosage Strength : 240MG/ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

Biophore

02

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Iohexol

Brand Name :

Dosage Form : Injection

Dosage Strength : 300MG/ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Biophore

02

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

Flag India
Digital Content Digital Content

Packaging :

Regulatory Info :

Iohexol

Dosage : Injection

Dosage Strength : 300MG/ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

Biophore

03

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Iohexol

Brand Name :

Dosage Form : Injection

Dosage Strength : 350MG/ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Biophore

03

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

Flag India
Digital Content Digital Content

Packaging :

Regulatory Info :

Iohexol

Dosage : Injection

Dosage Strength : 350MG/ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

Biophore

04

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothNaprod is a top player in Oncology & Anesthesia FDF through excellent innovation, discovery of new processes & high-quality production.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Iohexol

Brand Name :

Dosage Form : Liquid Injection

Dosage Strength : 755MG/ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Naprod Life Sciences

04

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothNaprod is a top player in Oncology & Anesthesia FDF through excellent innovation, discovery of new processes & high-quality production.

Flag India
Digital Content Digital Content

Packaging :

Regulatory Info :

Iohexol

Dosage : Liquid Injection

Dosage Strength : 755MG/ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

Naprod Life Sciences

05

AusBiotech 2024
Not Confirmed
arrow
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name :

Dosage Form : Injection

Dosage Strength : 51.8%

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

blank

05

AusBiotech 2024
Not Confirmed
arrow
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Dosage : Injection

Dosage Strength : 51.8%

Brand Name :

Approval Date :

Application Number :

Registration Country : China

blank

06

AusBiotech 2024
Not Confirmed
arrow
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name :

Dosage Form : Injection

Dosage Strength : 64.7%

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

blank

06

AusBiotech 2024
Not Confirmed
arrow
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Dosage : Injection

Dosage Strength : 64.7%

Brand Name :

Approval Date :

Application Number :

Registration Country : China

blank

07

AusBiotech 2024
Not Confirmed
arrow
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name :

Dosage Form : Injection

Dosage Strength : 75.5%

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

blank

07

AusBiotech 2024
Not Confirmed
arrow
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Dosage : Injection

Dosage Strength : 75.5%

Brand Name :

Approval Date :

Application Number :

Registration Country : China

blank

08

AusBiotech 2024
Not Confirmed
arrow
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name :

Dosage Form : Injection

Dosage Strength : 240MGI/1ML

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

blank

08

AusBiotech 2024
Not Confirmed
arrow
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Dosage : Injection

Dosage Strength : 240MGI/1ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

09

AusBiotech 2024
Not Confirmed
arrow
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name :

Dosage Form : Injection

Dosage Strength : 300MGI/1ML

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

blank

09

AusBiotech 2024
Not Confirmed
arrow
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Dosage : Injection

Dosage Strength : 300MGI/1ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

10

AusBiotech 2024
Not Confirmed
arrow
arrow
AusBiotech 2024
Not Confirmed

Iohexol

Brand Name :

Dosage Form : Injection

Dosage Strength : 30G

Packaging : 100mL:30g(I)

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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AusBiotech 2024
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AusBiotech 2024
Not Confirmed

Iohexol

Dosage : Injection

Dosage Strength : 30G

Brand Name :

Approval Date :

Application Number :

Registration Country : China

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