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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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$ 0

MARKET PLACE

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API

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

FDF Dossiers

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

PATENTS & EXCLUSIVITIES

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US Patents

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Data Compilation #PharmaFlow

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Stock Recap #PipelineProspector

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News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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Finished Drug Prices

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Chemistry

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Also known as: 56092-81-0, Ionomycin free acid, Sq 23377, Sq-23377, Chebi:63954, 54v905v6at
Molecular Formula
C41H72O9
Molecular Weight
709.0  g/mol
InChI Key
PGHMRUGBZOYCAA-ADZNBVRBSA-N
FDA UNII
54V905V6AT

Ionomycin
A divalent calcium ionophore that is widely used as a tool to investigate the role of intracellular calcium in cellular processes.
1 2D Structure

Ionomycin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-22-[(2S,5S)-5-[(2R,5S)-5-[(1R)-1-hydroxyethyl]-5-methyloxolan-2-yl]-5-methyloxolan-2-yl]-4,6,8,12,14,18,20-heptamethyl-9-oxodocosa-10,16-dienoic acid
2.1.2 InChI
InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47)/b13-11+,34-24-/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+/m1/s1
2.1.3 InChI Key
PGHMRUGBZOYCAA-ADZNBVRBSA-N
2.1.4 Canonical SMILES
CC(CCC(=O)O)CC(C)CC(C)C(=O)C=C(C(C)CC(C)CC=CC(C)C(C(C)C(CC1CCC(O1)(C)C2CCC(O2)(C)C(C)O)O)O)O
2.1.5 Isomeric SMILES
C[C@H](CCC(=O)O)C[C@H](C)C[C@H](C)C(=O)/C=C(/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@H]([C@@H](C)[C@H](C[C@@H]1CC[C@@](O1)(C)[C@H]2CC[C@@](O2)(C)[C@@H](C)O)O)O)\O
2.2 Other Identifiers
2.2.1 UNII
54V905V6AT
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Sq 23377

2. Sq-23377

3. Sq23377

2.3.2 Depositor-Supplied Synonyms

1. 56092-81-0

2. Ionomycin Free Acid

3. Sq 23377

4. Sq-23377

5. Chebi:63954

6. 54v905v6at

7. (4r,6s,8s,10z,12r,14r,16e,18r,19r,20s,21s)-11,19,21-trihydroxy-22-[(2s,5s)-5-[(2r,5s)-5-[(1r)-1-hydroxyethyl]-5-methyloxolan-2-yl]-5-methyloxolan-2-yl]-4,6,8,12,14,18,20-heptamethyl-9-oxodocosa-10,16-dienoic Acid

8. (4r,6s,8s,10z,12r,14r,16e,18r,19r,20s,21s)-11,19,21-trihydroxy-22-{(2s,2'r,5s,5's)-5'-[(1r)-1-hydroxyethyl]-2,5'-dimethyloctahydro-2,2'-bifuran-5-yl}-4,6,8,12,14,18,20-heptamethyl-9-oxodocosa-10,16-dienoic Acid

9. (4r,6s,8s,10z,12r,14r,16e,18r,19r,20s,21s)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2s,2'r,5s,5's)-octahydro-5'-[(1r)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic Acid

10. Ionomycin, Free Acid, Streptomyces Conglobatus

11. C41h72o9

12. Unii-54v905v6at

13. Chembl501617

14. Dtxsid2040521

15. Schembl17265597

16. Hms3403i13

17. Hsci1_000207

18. Akos024456942

19. Akos037645010

20. Zinc169289396

21. As-56129

22. Hy-13434

23. Cs-0006887

24. Ionomycin From Streptomyces Conglobatus, >=98% (hplc)

25. (4r,6s,8s,10z,12r,14r,16e,18r,19r,20s,21s)-11,19,21-trihydroxy-22-((2s,2'r,5s,5's)-5'-((r)-1-hydroxyethyl)-2,5'-dimethyloctahydro-[2,2'-bifuran]-5-yl)-4,6,8,12,14,18,20-heptamethyl-9-oxodocosa-10,16-dienoic Acid

26. (4r,6s,8s,10z,12r,14r,16e,18r,19r,20s,21s)-11,19,21-trihydroxy-22-((2s,2'r,5s,5's)-5'-((r)-1-hydroxyethyl)-2,5'-dimethyloctahydro-[2,2'-bifuran]-5-yl)-4,6,8,12,14,18,20-heptamethyl-9-oxodocosa-10,16-dienoicacid

27. 10,16-docosadienoic Acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-((2s,2'r,5s,5's)-octahydro-5'-((1r)-1-hydroxyethyl)-2,5'-dimethyl(2,2'-bifuran)-5-yl)-9-oxo-, (4r,6s,8s,10z,12r,14r,16e,18r,19r,20s,21s)-

28. 10,16-docosadienoic Acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2s,2'r,5s,5's)-octahydro-5'-[(1r)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, (4r,6s,8s,10z,12r,14r,16e,1 8r,19r,20s,21s)-

2.4 Create Date
2006-07-04
3 Chemical and Physical Properties
Molecular Weight 709.0 g/mol
Molecular Formula C41H72O9
XLogP37.5
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count9
Rotatable Bond Count22
Exact Mass708.51763387 g/mol
Monoisotopic Mass708.51763387 g/mol
Topological Polar Surface Area154 Ų
Heavy Atom Count50
Formal Charge0
Complexity1120
Isotope Atom Count0
Defined Atom Stereocenter Count14
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Calcium Ionophores

Chemical agents that increase the permeability of CELL MEMBRANES to CALCIUM ions. (See all compounds classified as Calcium Ionophores.)


ABOUT THIS PAGE

Ionomycin Manufacturers

A Ionomycin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ionomycin, including repackagers and relabelers. The FDA regulates Ionomycin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ionomycin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ionomycin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ionomycin Suppliers

A Ionomycin supplier is an individual or a company that provides Ionomycin active pharmaceutical ingredient (API) or Ionomycin finished formulations upon request. The Ionomycin suppliers may include Ionomycin API manufacturers, exporters, distributors and traders.

click here to find a list of Ionomycin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ionomycin GMP

Ionomycin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ionomycin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ionomycin GMP manufacturer or Ionomycin GMP API supplier for your needs.

Ionomycin CoA

A Ionomycin CoA (Certificate of Analysis) is a formal document that attests to Ionomycin's compliance with Ionomycin specifications and serves as a tool for batch-level quality control.

Ionomycin CoA mostly includes findings from lab analyses of a specific batch. For each Ionomycin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ionomycin may be tested according to a variety of international standards, such as European Pharmacopoeia (Ionomycin EP), Ionomycin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ionomycin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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