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Chemistry

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Also known as: Ethyl 10-(4-iodophenyl)undecanoate, 99-79-6, Iofendylatum, Ethyl 10-(p-iodophenyl)undecylate, Ethyl 10-(p-iodophenyl)hendecanoate, 6v3i57k9ul
Molecular Formula
C19H29IO2
Molecular Weight
416.3  g/mol
InChI Key
LAYLQVBQIBQVLL-UHFFFAOYSA-N
FDA UNII
6V3I57K9UL

Iophendylate
An inert iodine-containing agent which is opaque to X-RAYS. It is used mainly for BRAIN and SPINAL CORD visualization.
1 2D Structure

Iophendylate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
ethyl 10-(4-iodophenyl)undecanoate
2.1.2 InChI
InChI=1S/C19H29IO2/c1-3-22-19(21)11-9-7-5-4-6-8-10-16(2)17-12-14-18(20)15-13-17/h12-16H,3-11H2,1-2H3
2.1.3 InChI Key
LAYLQVBQIBQVLL-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCOC(=O)CCCCCCCCC(C)C1=CC=C(C=C1)I
2.2 Other Identifiers
2.2.1 UNII
6V3I57K9UL
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ethiodan

2. Iodophendylate

3. Ioglunide

4. Iophendylate

5. Isophendylate

6. Maiodil

7. Myodil

8. Panthopaque

9. Pantopaque

2.3.2 Depositor-Supplied Synonyms

1. Ethyl 10-(4-iodophenyl)undecanoate

2. 99-79-6

3. Iofendylatum

4. Ethyl 10-(p-iodophenyl)undecylate

5. Ethyl 10-(p-iodophenyl)hendecanoate

6. 6v3i57k9ul

7. Jofendylatum

8. Iophendylate, P-

9. Ethiodan

10. Mulsopaque

11. Neurotrast

12. Myodil

13. Myodyl

14. Mulsopaque; Myodil; Myodyl; Neurotrast; Pantopaque

15. Iofendilato

16. P-iophendylate

17. Iofendylatum [inn-latin]

18. Iofendilato [inn-spanish]

19. Hsdb 3346

20. Ethyl 10-(p-iodophenyl)undecanoate

21. Iofendylate [inn:ban]

22. Einecs 202-787-8

23. Brn 2661373

24. Unii-6v3i57k9ul

25. Iophendilate

26. Undecanoic Acid, 10-(p-iodophenyl)-, Ethyl Ester

27. Jofendylate

28. Benzenedecanoic Acid, 4-iodo-iota-methyl-, Ethyl Ester

29. Iophendylate [mi]

30. Chembl951

31. 3-09-00-02627 (beilstein Handbook Reference)

32. Schembl492663

33. Dtxsid2052869

34. Ethyl10-(4-iodophenyl)undecanoate

35. Hy-a0223

36. Akos005267217

37. Cs-0017569

38. Ft-0682962

39. Q3801357

40. W-100019

41. Benzenedecanoic Acid, 4-iodo-.iota.-methyl-, Ethyl Ester

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 416.3 g/mol
Molecular Formula C19H29IO2
XLogP37
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count12
Exact Mass416.12123 g/mol
Monoisotopic Mass416.12123 g/mol
Topological Polar Surface Area26.3 Ų
Heavy Atom Count22
Formal Charge0
Complexity285
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Therapeutic Uses

Contrast Media

National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)


IT IS ABSORBABLE, IODIZED FATTY ACID COMPD OF LOW VISCOSITY DESIGNED ESPECIALLY FOR MYELOGRAPHY. ... IT IS EQUALLY USEFUL FOR VISUALIZATION OF ALL REGIONS OF SPINAL CORD, ALTHOUGH THIS MAY BE TECHNICALLY MORE DIFFICULT IN CERVICAL & THORACIC REGIONS. ... IOPHENDYLATE ALSO IS USED IN EMULSIFIED AQUEOUS FORM AS CONTRAST MEDIUM FOR VISUALIZATION OF BILIARY TREE, SINUS TRACTS, & CERTAIN BODY CAVITIES.

Goodman, L.S., and A. Gilman. (eds.) The Pharmacological Basis of Therapeutics. 5th ed. New York: Macmillan Publishing Co., Inc., 1975., p. 802


IT IS COMMONLY USED FOR VISUALIZATION OF TUMORS OR HERNIATION OF INTERVERTEBRAL DISC OR OTHER LESIONS COMPRESSING SPINAL CORD.

Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 1215


VET: TO OUTLINE SALIVARY GLANDS, DRAINING SINUSES, OR FISTULAS; IT MAY BE SAFE (1-3 ML) IN SPINAL VENTRICULOGRAPHY OF DOGS.

Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 285


DOSE- USUAL, MYELOGRAPHY, INTRATHECAL OR BY SPECIAL INJECTION

Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 1215


4.2 Drug Warning

THIS AGENT SHOULD NOT BE USED INTRAVASCULARLY. ... AGENT SHOULD NOT BE USED WHEN LUMBAR PUNCTURE IS CONTRAINDICATED; &, TO AVOID SUBDURAL & EXTRA-ARACHNOID EXTRAVASATION, IT SHOULD NOT BE EMPLOYED WITHIN 10 DAYS OF PREVIOUS LUMBAR PUNCTURE.

Goodman, L.S., and A. Gilman. (eds.) The Pharmacological Basis of Therapeutics. 5th ed. New York: Macmillan Publishing Co., Inc., 1975., p. 802


...PERSISTENT LEVELS IN BODY INTERFERE WITH TRACER STUDIES WITH RADIOACTIVE IODINE.

Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 1215


WHEN BULK OF MATERIAL IS REMOVED...INCIDENCE OF SIDE REACTIONS IS LOW.

Goodman, L.S., and A. Gilman. (eds.) The Pharmacological Basis of Therapeutics. 5th ed. New York: Macmillan Publishing Co., Inc., 1975., p. 802


IN GENERAL, IODINATED CONTRAST MEDIA SHOULD BE ADMINISTERED WITH CAUTION IN PATIENTS WITH HEPATIC OR RENAL DYSFUNCTION. ... THE INJECTION OF IODIZED FATTY ACIDS IS ESSENTIALLY A SURGICAL PROCEDURE THAT INVOLVES RISK. THE FOLLOWING CAUTIONS SHOULD BE BORNE IN MIND. PREPARATIONS THAT HAVE AGED & DARKENED BEYOND THE ORIGINAL COLOR SHOULD NOT BE USED. ... THE COMPOUNDS SHOULD NOT BE ADMINISTERED TO INDIVIDUALS WITH HISTORY OF SENSITIVITY TO IODIDES. /IODINATED CONTRAST MEDIA/

Goodman, L.S., and A. Gilman. (eds.) The Pharmacological Basis of Therapeutics. 5th ed. New York: Macmillan Publishing Co., Inc., 1975., p. 803


For more Drug Warnings (Complete) data for IOPHENDYLATE (6 total), please visit the HSDB record page.


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Contrast Media

Substances used to allow enhanced visualization of tissues. (See all compounds classified as Contrast Media.)


5.2 ATC Code

V - Various

V08 - Contrast media

V08A - X-ray contrast media, iodinated

V08AD - Non-watersoluble x-ray contrast media

V08AD04 - Iofendylate


5.3 Absorption, Distribution and Excretion

WHEN EXAM IS COMPLETED, COMPD SHOULD BE REMOVED BY ASPIRATION. WHEN BULK OF MATERIAL IS REMOVED, REMAINDER IS ABSORBED WITHIN FEW MONTHS...

Goodman, L.S., and A. Gilman. (eds.) The Pharmacological Basis of Therapeutics. 5th ed. New York: Macmillan Publishing Co., Inc., 1975., p. 802


ABOUT THIS PAGE

Looking for 99-79-6 / Iophendylate API manufacturers, exporters & distributors?

Iophendylate manufacturers, exporters & distributors 1

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Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Iophendylate manufacturer or Iophendylate supplier.

PharmaCompass also assists you with knowing the Iophendylate API Price utilized in the formulation of products. Iophendylate API Price is not always fixed or binding as the Iophendylate Price is obtained through a variety of data sources. The Iophendylate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Iophendylate

Synonyms

Ethyl 10-(4-iodophenyl)undecanoate, 99-79-6, Iofendylatum, Ethyl 10-(p-iodophenyl)undecylate, Ethyl 10-(p-iodophenyl)hendecanoate, 6v3i57k9ul

Cas Number

99-79-6

Unique Ingredient Identifier (UNII)

6V3I57K9UL

About Iophendylate

An inert iodine-containing agent which is opaque to X-RAYS. It is used mainly for BRAIN and SPINAL CORD visualization.

Iophendylate Manufacturers

A Iophendylate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Iophendylate, including repackagers and relabelers. The FDA regulates Iophendylate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Iophendylate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Iophendylate Suppliers

A Iophendylate supplier is an individual or a company that provides Iophendylate active pharmaceutical ingredient (API) or Iophendylate finished formulations upon request. The Iophendylate suppliers may include Iophendylate API manufacturers, exporters, distributors and traders.

Iophendylate GMP

Iophendylate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Iophendylate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Iophendylate GMP manufacturer or Iophendylate GMP API supplier for your needs.

Iophendylate CoA

A Iophendylate CoA (Certificate of Analysis) is a formal document that attests to Iophendylate's compliance with Iophendylate specifications and serves as a tool for batch-level quality control.

Iophendylate CoA mostly includes findings from lab analyses of a specific batch. For each Iophendylate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Iophendylate may be tested according to a variety of international standards, such as European Pharmacopoeia (Iophendylate EP), Iophendylate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Iophendylate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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