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Chemistry

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Also known as: Sodium iothalamate, 1225-20-3, Angio-conray, Sodium iotalamate, Iotalamate sodium, Iothalamic acid sodium salt
Molecular Formula
C11H8I3N2NaO4
Molecular Weight
635.89  g/mol
InChI Key
WCIMWHNSWLLELS-UHFFFAOYSA-M
FDA UNII
KDN276D83N

Iothalamate Sodium
A contrast medium in diagnostic radiology with properties similar to those of diatrizoic acid. It is used primarily as its sodium and meglumine (IOTHALAMATE MEGLUMINE) salts.
1 2D Structure

Iothalamate Sodium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoate
2.1.2 InChI
InChI=1S/C11H9I3N2O4.Na/c1-3(17)16-9-7(13)4(10(18)15-2)6(12)5(8(9)14)11(19)20;/h1-2H3,(H,15,18)(H,16,17)(H,19,20);/q;+1/p-1
2.1.3 InChI Key
WCIMWHNSWLLELS-UHFFFAOYSA-M
2.1.4 Canonical SMILES
CC(=O)NC1=C(C(=C(C(=C1I)C(=O)[O-])I)C(=O)NC)I.[Na+]
2.2 Other Identifiers
2.2.1 UNII
KDN276D83N
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Acid, Iotalamic

2. Acid, Iothalamic

3. Acid, Methalamic

4. Angio Conray

5. Angio-conray

6. Angioconray

7. Conray 420

8. Iodothalamate

9. Iotalamic Acid

10. Iothalamate

11. Iothalamate, Sodium

12. Iothalamic Acid

13. Iothalamic Acid, Calcium (2:1) Salt

14. Iothalamic Acid, Monosilver (1+) Salt

15. Iothalamic Acid, Monosodium Salt

16. Iothalamic Acid, Monosodium Salt, Dimer

17. Lopamidol

18. Methalamic Acid

19. Sodium Iothalamate

2.3.2 Depositor-Supplied Synonyms

1. Sodium Iothalamate

2. 1225-20-3

3. Angio-conray

4. Sodium Iotalamate

5. Iotalamate Sodium

6. Iothalamic Acid Sodium Salt

7. Iothalamate (sodium)

8. Iothalamate Sodium [usp]

9. Sodium Iotalamate Injection

10. Kdn276d83n

11. Monosodium 5-acetamido-2,4,6-triiodo-n-methylisophthalamate

12. Sodium;3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoate

13. Benzoic Acid, 3-(acetylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)-, Monosodium Salt

14. Mediocontrix

15. Angio-contrix

16. Iothalamate Sodium (usp)

17. Conray 80

18. Conray 300

19. Conray 325

20. Conray 400

21. Conray-400

22. Iothalamate Sodium Salt

23. Sodium 3-(acetylamino)-2,4,6-triiodo-5-[(methylamino)carbonyl]benzoate

24. Benzoic Acid, 3-(acetylamino)-2,4,6-triiodo-5-[(methylamino)carbonyl]-, Monosodium Salt

25. Iotalamate De Sodium

26. Iotalamate De Sodium [french]

27. Iothalamate Sodium (injection)

28. Sodium 3-(acetylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)benzoate

29. Einecs 214-955-8

30. Unii-kdn276d83n

31. Conray 400 (tn)

32. 5-acetylamino-n-methyl-2,4,6-triiodoisophthalamic Acid Sodium Salt

33. Isophthalamic Acid, 5-acetamido-2,4,6-triiodo-n-methyl-, Monosodium Salt

34. Sodium Iotalamate (jp17)

35. Dsstox_cid_31457

36. Dsstox_rid_97343

37. Dsstox_gsid_57668

38. Schembl159919

39. Sodium Iotalamate [jan]

40. Chembl1097620

41. Dtxsid1057668

42. Sodium Iotalamate [mart.]

43. Iothalamate Sodium [vandf]

44. Iotalamate Sodium [who-dd]

45. Tox21_113735

46. Isophthalamic Acid, 5-acetamido-2,4,6-triiodo-n-methyl-, Sodium Salt

47. Iothalamate Sodium [orange Book]

48. Isophthalamic Acid, 5-acetylamino-n-methyl-2,4,6-triiodo-, Sodium Salt

49. Iothalamate Sodium [usp Impurity]

50. Iothalamic Acid Sodium Salt [mi]

51. Ncgc00253600-01

52. Cas-1225-20-3

53. Vascoray Component Iothalamate Sodium

54. D03603

55. Iothalamate Sodium Component Of Vascoray

56. Q27282205

57. Sodium3-(acetylamino)-2,4,6-triiodo-5-[(methylamino)carbonyl]benzoate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 635.89 g/mol
Molecular Formula C11H8I3N2NaO4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass635.7516 g/mol
Monoisotopic Mass635.7516 g/mol
Topological Polar Surface Area98.3 Ų
Heavy Atom Count21
Formal Charge0
Complexity426
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Contrast Media

Substances used to allow enhanced visualization of tissues. (See all compounds classified as Contrast Media.)


ABOUT THIS PAGE

Iothalamate Sodium Manufacturers

A Iothalamate Sodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Iothalamate Sodium, including repackagers and relabelers. The FDA regulates Iothalamate Sodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Iothalamate Sodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Iothalamate Sodium Suppliers

A Iothalamate Sodium supplier is an individual or a company that provides Iothalamate Sodium active pharmaceutical ingredient (API) or Iothalamate Sodium finished formulations upon request. The Iothalamate Sodium suppliers may include Iothalamate Sodium API manufacturers, exporters, distributors and traders.

click here to find a list of Iothalamate Sodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Iothalamate Sodium USDMF

A Iothalamate Sodium DMF (Drug Master File) is a document detailing the whole manufacturing process of Iothalamate Sodium active pharmaceutical ingredient (API) in detail. Different forms of Iothalamate Sodium DMFs exist exist since differing nations have different regulations, such as Iothalamate Sodium USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Iothalamate Sodium DMF submitted to regulatory agencies in the US is known as a USDMF. Iothalamate Sodium USDMF includes data on Iothalamate Sodium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Iothalamate Sodium USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Iothalamate Sodium suppliers with USDMF on PharmaCompass.

Iothalamate Sodium GMP

Iothalamate Sodium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Iothalamate Sodium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Iothalamate Sodium GMP manufacturer or Iothalamate Sodium GMP API supplier for your needs.

Iothalamate Sodium CoA

A Iothalamate Sodium CoA (Certificate of Analysis) is a formal document that attests to Iothalamate Sodium's compliance with Iothalamate Sodium specifications and serves as a tool for batch-level quality control.

Iothalamate Sodium CoA mostly includes findings from lab analyses of a specific batch. For each Iothalamate Sodium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Iothalamate Sodium may be tested according to a variety of international standards, such as European Pharmacopoeia (Iothalamate Sodium EP), Iothalamate Sodium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Iothalamate Sodium USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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