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Chemistry

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Also known as: Meglumine ioxaglate, Ioxaglate meglumine [usan], 59018-13-2, Mp 302 (mixt. with ioxaglate sodium), Hexabrix, 75jr975t11
Molecular Formula
C31H38I6N6O13
Molecular Weight
1464.1  g/mol
InChI Key
HUHDYASLFWQVOL-WZTVWXICSA-N
FDA UNII
75JR975T11

Ioxaglate Meglumine
A low-osmolar, ionic contrast medium used in various radiographic procedures.
1 2D Structure

Ioxaglate Meglumine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-[[2-[[3-[acetyl(methyl)amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoyl]amino]acetyl]amino]-5-(2-hydroxyethylcarbamoyl)-2,4,6-triiodobenzoic acid;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
2.1.2 InChI
InChI=1S/C24H21I6N5O8.C7H17NO5/c1-7(37)35(3)20-17(29)10(21(39)31-2)13(25)11(18(20)30)23(41)33-6-8(38)34-19-15(27)9(22(40)32-4-5-36)14(26)12(16(19)28)24(42)43;1-8-2-4(10)6(12)7(13)5(11)3-9/h36H,4-6H2,1-3H3,(H,31,39)(H,32,40)(H,33,41)(H,34,38)(H,42,43);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
2.1.3 InChI Key
HUHDYASLFWQVOL-WZTVWXICSA-N
2.1.4 Canonical SMILES
CC(=O)N(C)C1=C(C(=C(C(=C1I)C(=O)NCC(=O)NC2=C(C(=C(C(=C2I)C(=O)O)I)C(=O)NCCO)I)I)C(=O)NC)I.CNCC(C(C(C(CO)O)O)O)O
2.1.5 Isomeric SMILES
CC(=O)N(C)C1=C(C(=C(C(=C1I)C(=O)NCC(=O)NC2=C(C(=C(C(=C2I)C(=O)O)I)C(=O)NCCO)I)I)C(=O)NC)I.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
75JR975T11
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Hexabrix

2. Ioxaglate

3. Ioxaglate Sodium

4. Ioxaglate, Methylglucamine

5. Ioxaglic Acid

6. Ioxaglic Acid Monosodium Salt

7. Ioxaglic Acid, Calcium Salt (2:1)

8. Meglumine, Ioxaglate

9. Methylglucamine Ioxaglate

10. P-286 (contrast Media)

11. P286 (contrast Media)

2.3.2 Depositor-Supplied Synonyms

1. Meglumine Ioxaglate

2. Ioxaglate Meglumine [usan]

3. 59018-13-2

4. Mp 302 (mixt. With Ioxaglate Sodium)

5. Hexabrix

6. 75jr975t11

7. Ioxaglate Meglumine (usan)

8. N-(2-hydroxyethyl)-2,4,6-triiodo-5-(2-(2,4,6-triiodo-3-(n-methylacetamido)-5-(methylcarbamoyl)benzamido)acetamido)isophthalamic Acid, Compound With 1-deoxy-1-(methylamino)-d-glucitol (1:1)

9. 3-[[2-[[3-[acetyl(methyl)amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoyl]amino]acetyl]amino]-5-(2-hydroxyethylcarbamoyl)-2,4,6-triiodobenzoic Acid;(2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentol

10. Benzoic Acid, 3-((((3-(acetylmethylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)benzoyl)amino)acetyl)amino)-5-(((2-hydroxyethyl)amino)carbonyl)-2,4,6-triiodo-, Compound With 1-deoxy-1-(methylamino)-d-glucitol (1:1)

11. Ioxagluc Acid

12. Unii-75jr975t11

13. Einecs 261-561-7

14. Mp 302 (mixt.with Iosaglate Sodium)

15. Schembl666706

16. Chembl1200508

17. Ioxaglate Meglumine [vandf]

18. Meglumine Ioxaglate [mart.]

19. Ioxaglate Meglumine [who-dd]

20. Mp-302

21. Ioxaglate Meglumine [orange Book]

22. Hexabrix Component Ioxaglate Meglumine

23. D04598

24. Ioxaglate Meglumine Component Of Hexabrix

25. Q27266396

26. 1-deoxy-1-(methylamino)-d-glucitol 3-((((3-(acetylmethylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)benzoyl)amino)acetyl)amino)-5-(((2-hydroxyethyl)amino)carbonyl)-2,4,6-triiodobenzoate

2.4 Create Date
2007-12-05
3 Chemical and Physical Properties
Molecular Weight 1464.1 g/mol
Molecular Formula C31H38I6N6O13
Hydrogen Bond Donor Count12
Hydrogen Bond Acceptor Count14
Rotatable Bond Count16
Exact Mass1463.6765 g/mol
Monoisotopic Mass1463.6765 g/mol
Topological Polar Surface Area307 Ų
Heavy Atom Count56
Formal Charge0
Complexity1220
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Contrast Media

Substances used to allow enhanced visualization of tissues. (See all compounds classified as Contrast Media.)


ABOUT THIS PAGE

Ioxaglate Meglumine Manufacturers

A Ioxaglate Meglumine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ioxaglate Meglumine, including repackagers and relabelers. The FDA regulates Ioxaglate Meglumine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ioxaglate Meglumine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Ioxaglate Meglumine Suppliers

A Ioxaglate Meglumine supplier is an individual or a company that provides Ioxaglate Meglumine active pharmaceutical ingredient (API) or Ioxaglate Meglumine finished formulations upon request. The Ioxaglate Meglumine suppliers may include Ioxaglate Meglumine API manufacturers, exporters, distributors and traders.

Ioxaglate Meglumine GMP

Ioxaglate Meglumine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ioxaglate Meglumine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ioxaglate Meglumine GMP manufacturer or Ioxaglate Meglumine GMP API supplier for your needs.

Ioxaglate Meglumine CoA

A Ioxaglate Meglumine CoA (Certificate of Analysis) is a formal document that attests to Ioxaglate Meglumine's compliance with Ioxaglate Meglumine specifications and serves as a tool for batch-level quality control.

Ioxaglate Meglumine CoA mostly includes findings from lab analyses of a specific batch. For each Ioxaglate Meglumine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ioxaglate Meglumine may be tested according to a variety of international standards, such as European Pharmacopoeia (Ioxaglate Meglumine EP), Ioxaglate Meglumine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ioxaglate Meglumine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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