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Chemistry

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Also known as: Sodium iopodate, Sodium ipodate, 1221-56-3, Bilivist, Biloptin, Oragrafin sodium
Molecular Formula
C12H12I3N2NaO2
Molecular Weight
619.94  g/mol
InChI Key
ZFHZUGUCWJVEQC-UHFFFAOYSA-M
FDA UNII
F316LLW9WW

Ipodate
Ionic monomeric contrast media. Usually the sodium or calcium salts are used for examination of the gall bladder and biliary tract. (From Martindale, The Extra Pharmacopoeia, 30th ed, p704)
1 2D Structure

Ipodate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;3-[3-(dimethylaminomethylideneamino)-2,4,6-triiodophenyl]propanoate
2.1.2 InChI
InChI=1S/C12H13I3N2O2.Na/c1-17(2)6-16-12-9(14)5-8(13)7(11(12)15)3-4-10(18)19;/h5-6H,3-4H2,1-2H3,(H,18,19);/q;+1/p-1
2.1.3 InChI Key
ZFHZUGUCWJVEQC-UHFFFAOYSA-M
2.1.4 Canonical SMILES
CN(C)C=NC1=C(C=C(C(=C1I)CCC(=O)[O-])I)I.[Na+]
2.2 Other Identifiers
2.2.1 UNII
F316LLW9WW
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3-(3-(dimethylaminomethylideneamino)-2,4,6-triiodophenyl)propanoic Acid

2. Benzenepropanoic Acid, 3-(((dimethylamino)methylene)amino)-2,4,6-triiodo-

3. Bilimin

4. Biloptin

5. Calcium Iopodate

6. Calcium Ipodate

7. Iopodate

8. Iopodate, Calcium

9. Iopodate, Sodium

10. Ipodate

11. Ipodate, Calcium

12. Ipodate, Sodium

13. Sodium Iopodate

14. Sodium Ipodate

15. Solu Biloptin

16. Solu-biloptin

2.3.2 Depositor-Supplied Synonyms

1. Sodium Iopodate

2. Sodium Ipodate

3. 1221-56-3

4. Bilivist

5. Biloptin

6. Oragrafin Sodium

7. Ipodate Sodium Salt

8. Biloptinon

9. Sodium 3-(3-{[(dimethylamino)methylene]amino}-2,4,6-triiodophenyl)propanoate

10. Nsc-106962

11. Sodium Iopodate (jan)

12. Ipodate Sodium [usan]

13. Iopodate Sodium

14. Sodium Triiodohydrocinnamate

15. Sodium Iopodate [inn]

16. Sodium Iopodate [jan]

17. F316llw9ww

18. Zk 15

19. Sh 514

20. Sodium 3-(((dimethylamino)methylene)amino)-2,4,6-triiodohydrocinnamate

21. Benzenepropanoic Acid, 3-(((dimethylamino)methylene)amino)-2,4,6-triiodo-, Sodium Salt

22. Ipodate Sodium (usan)

23. Oragrafin-sodium

24. Orgrafin

25. Iodopato Sodico

26. Natrii Iopodas

27. Benzenepropanoic Acid, 3-[[(dimethylamino)methylene]amino]-2,4,6-triiodo-, Sodium Salt

28. Iopodate De Sodium

29. Natrii Iopodas [inn-latin]

30. Iodopato Sodico [inn-spanish]

31. Iopodate De Sodium [inn-french]

32. Ncgc00181092-01

33. Einecs 214-945-3

34. Unii-f316llw9ww

35. Ipodate Sodium [usan:usp]

36. Sq-15761

37. Oragrafin Sodium (tn)

38. 3-((dimethylaminomethylene)amino)-2,4,6-triiodohydrocinnamic Acid Sodium Salt

39. Beta-(2,4,6-trijod-3-dimethylaminomethylenamino-phenyl)-propionsaeure [german]

40. Benzenepropanoic Acid, 3-((dimethylaminomethylene)amino)-2,4,6-triiodo-, Sodium Salt

41. Dsstox_cid_28246

42. Dsstox_rid_82748

43. Sodium Salt Of 3-(3-dimethylaminomethyleneamino-2,4,6-triiodophenyl)propionic Acid

44. Dsstox_gsid_48271

45. Ipodatesodium(200mg)

46. Ipodate Sodium [vandf]

47. Chebi:5953

48. Chembl1201033

49. Chembl3184539

50. Dtxsid9048271

51. Sodium Iopodate [mart.]

52. Iopodate Sodium [who-dd]

53. Ipodate Sodium Salt [mi]

54. Baa22156

55. Tox21_112708

56. Beta-(2,4,6-trijod-3-dimethylaminomethylenamino-phenyl)-propionsaeure

57. Ipodate Sodium [orange Book]

58. Ipodate Sodium [usp Impurity]

59. Akos005111003

60. Sodium;3-[3-(dimethylaminomethylideneamino)-2,4,6-triiodophenyl]propanoate

61. Hydrocinnamic Acid, 3-((dimethylaminomethylene)amino)-2,4,6-triiodo-, Sodium Salt

62. Cas-1221-56-3

63. Ft-0682674

64. D01015

65. Q15409424

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 619.94 g/mol
Molecular Formula C12H12I3N2NaO2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass619.7931 g/mol
Monoisotopic Mass619.7931 g/mol
Topological Polar Surface Area55.7 Ų
Heavy Atom Count20
Formal Charge0
Complexity345
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Contrast Media

Substances used to allow enhanced visualization of tissues. (See all compounds classified as Contrast Media.)


4.2 ATC Code

V - Various

V08 - Contrast media

V08A - X-ray contrast media, iodinated

V08AC - Watersoluble, hepatotropic x-ray contrast media

V08AC08 - Sodium iopodate


ABOUT THIS PAGE

Ipodate Manufacturers

A Ipodate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ipodate, including repackagers and relabelers. The FDA regulates Ipodate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ipodate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Ipodate Suppliers

A Ipodate supplier is an individual or a company that provides Ipodate active pharmaceutical ingredient (API) or Ipodate finished formulations upon request. The Ipodate suppliers may include Ipodate API manufacturers, exporters, distributors and traders.

click here to find a list of Ipodate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ipodate USDMF

A Ipodate DMF (Drug Master File) is a document detailing the whole manufacturing process of Ipodate active pharmaceutical ingredient (API) in detail. Different forms of Ipodate DMFs exist exist since differing nations have different regulations, such as Ipodate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Ipodate DMF submitted to regulatory agencies in the US is known as a USDMF. Ipodate USDMF includes data on Ipodate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ipodate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Ipodate suppliers with USDMF on PharmaCompass.

Ipodate GMP

Ipodate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ipodate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ipodate GMP manufacturer or Ipodate GMP API supplier for your needs.

Ipodate CoA

A Ipodate CoA (Certificate of Analysis) is a formal document that attests to Ipodate's compliance with Ipodate specifications and serves as a tool for batch-level quality control.

Ipodate CoA mostly includes findings from lab analyses of a specific batch. For each Ipodate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ipodate may be tested according to a variety of international standards, such as European Pharmacopoeia (Ipodate EP), Ipodate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ipodate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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