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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 35212-22-7, Osten, 7-isopropoxyisoflavone, Osteofix, Yambolap, Iprosten
Molecular Formula
C18H16O3
Molecular Weight
280.3  g/mol
InChI Key
SFBODOKJTYAUCM-UHFFFAOYSA-N
FDA UNII
80BJ7WN25Z

Ipriflavone
1 2D Structure

Ipriflavone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-phenyl-7-propan-2-yloxychromen-4-one
2.1.2 InChI
InChI=1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3
2.1.3 InChI Key
SFBODOKJTYAUCM-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C)OC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC=CC=C3
2.2 Other Identifiers
2.2.1 UNII
80BJ7WN25Z
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 7-isopropoxyisoflavone

2. Fl-113

3. Osteoquine

4. Quinogin

5. Yambolap

2.3.2 Depositor-Supplied Synonyms

1. 35212-22-7

2. Osten

3. 7-isopropoxyisoflavone

4. Osteofix

5. Yambolap

6. Iprosten

7. Ipriflavonum

8. Ipriflavona

9. Osteoquine

10. Ostivone

11. 7-isopropoxy-3-phenyl-4h-1-benzopyran-4-one

12. 3-phenyl-7-propan-2-yloxychromen-4-one

13. 7-isopropoxy-3-phenyl-4h-chromen-4-one

14. Ipriflavone [inn:jan]

15. Osten (tn)

16. Ipriflavone (osteofix)

17. Osteochin

18. Tc 80

19. 7-(1-methylethoxy)-3-phenyl-4h-1-benzopyran-4-one

20. Fl 113

21. Fl-113

22. Mls000069470

23. 3-phenyl-7-(propan-2-yloxy)-4h-chromen-4-one

24. Smr000059060

25. 4h-1-benzopyran-4-one, 7-(1-methylethoxy)-3-phenyl-

26. 80bj7wn25z

27. Chebi:31719

28. Nsc-755888

29. Ncgc00024094-04

30. Quinogin

31. Dsstox_cid_20679

32. Dsstox_rid_79537

33. Dsstox_gsid_40679

34. Iprivone

35. Ipriflavonum [inn-latin]

36. Ipriflavona [inn-spanish]

37. Cas-35212-22-7

38. Ccris 1920

39. Brn 4754346

40. Unii-80bj7wn25z

41. Ipriflavon

42. (ipriflavone)

43. Ipriflavone, Inn

44. 7-isoproxyisoflavone

45. Mfcd00221719

46. 7-isopropoxy-isoflavone

47. 7-isopropyloxy-isoflavone

48. Ipriflavone (jan/inn)

49. Ipriflavone [mi]

50. Opera_id_1176

51. Ipriflavone [inn]

52. Ipriflavone [jan]

53. Ipriflavone (jp17/inn)

54. Ipriflavone [vandf]

55. Cambridge Id 6663564

56. Cid_3747

57. Ipriflavone [mart.]

58. Oprea1_106310

59. Oprea1_275552

60. Ipriflavone [who-dd]

61. Mls000759494

62. Mls001146879

63. Mls001424060

64. Mls006011644

65. Schembl111472

66. 7-isopropoxy-3-phenyl-chromone

67. Chembl165790

68. Zinc4016

69. Ipriflavone, Analytical Standard

70. Dtxsid5040679

71. Bdbm43662

72. Sfbodokjtyaucm-uhfffaoysa-

73. Fl113

74. Hms2051j15

75. Hms2234m05

76. Hms3371e17

77. Hms3393j15

78. Hms3656k19

79. Hms3715d04

80. Tc-80

81. Tn-39

82. Amy25650

83. Hy-n0094

84. Tox21_111532

85. Tox21_113172

86. S2422

87. Stl512460

88. Akos003627375

89. Tox21_111532_1

90. Tox21_113172_1

91. Ac-8130

92. Ccg-100963

93. Cs-6395

94. Db13618

95. Nc00213

96. Nsc 755888

97. Ncgc00018139-01

98. Ncgc00018139-02

99. Ncgc00018139-03

100. Ncgc00018139-04

101. Ncgc00018139-05

102. Ncgc00018139-07

103. Ncgc00018139-08

104. As-12306

105. 3-phenyl-7-propan-2-yloxy-chromen-4-one

106. Db-048754

107. Ft-0621442

108. I0669

109. Sw197593-2

110. 3-phenyl-7-propan-2-yloxy-1-benzopyran-4-one

111. D01338

112. D70301

113. Ab00384280-21

114. 212i227

115. A822650

116. Sr-01000000042

117. 7-isopropoxy-3-phenyl-4h-1-benzopyran-4-one 97%

118. Q1097778

119. Sr-01000000042-2

120. 7-isopropoxy-3-phenyl-4h-1-benzopyran-4-one, 97%

121. F0196-0909

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 280.3 g/mol
Molecular Formula C18H16O3
XLogP34
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass280.109944368 g/mol
Monoisotopic Mass280.109944368 g/mol
Topological Polar Surface Area35.5 Ų
Heavy Atom Count21
Formal Charge0
Complexity407
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

M - Musculo-skeletal system

M05 - Drugs for treatment of bone diseases

M05B - Drugs affecting bone structure and mineralization

M05BX - Other drugs affecting bone structure and mineralization

M05BX01 - Ipriflavone


4.2 Metabolism/Metabolites

Ipriflavone has known human metabolites that include 3-Phenyl-7-(1-methyl-2-hydroxyethoxy)-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 3-(4-hydroxyphenyl)-7-(1-methylethoxy)-, and 7-Hydroxyisoflavone.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


API SUPPLIERS

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TOKO PHARMACEUTICAL INDUSTRIES CO ...

Japan

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering
Not Confirmed
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TOKO PHARMACEUTICAL INDUSTRIES CO ...

Japan

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Antibody Engineering
Not Confirmed
USDMF CEP/COS JDMF arrow-down EU-WC NDC KDMF VMF Others AUDIT
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02

Sumitomo Chemical

Japan

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering
Not Confirmed
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Sumitomo Chemical

Japan

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Antibody Engineering
Not Confirmed
USDMF CEP/COS JDMF arrow-down EU-WC NDC KDMF VMF Others AUDIT
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03

Bio-gen Extracts

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering
Not Confirmed
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Bio-gen Extracts

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Antibody Engineering
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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JDMF

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Antibody Engineering
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Japanese Pharmacopoeia Ipriflavone

Registration Number : 222MF10198

Registrant's Address : 2-27-1 Shinkawa, Chuo-ku, Tokyo

Initial Date of Registration : 2010-07-13

Latest Date of Registration : 2010-07-13

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02

Antibody Engineering
Not Confirmed
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Japanese Pharmacopoeia Ipriflavone (for manufacturing only)

Registration Number : 223MF10047

Registrant's Address : 5 Kajigaishi Nishi 1-chome, Kitanagoya City, Aichi Prefecture

Initial Date of Registration : 2011-03-25

Latest Date of Registration : 2011-03-25

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Listed Suppliers

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Antibody Engineering
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ipriflavone

About the Company : Bio-gen Extracts Pvt. Ltd., India, established in the year 2000, is a GMP Certified fine chemicals company that specializes in the process development and manufacture of Active Pha...

Bio-gen Extracts Pvt. Ltd., India, established in the year 2000, is a GMP Certified fine chemicals company that specializes in the process development and manufacture of Active Pharmaceutical Ingredients, Therapeutic Enzymes, Specialty Polymers & Nutraceutical Raw Materials.
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API Reference Price

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03-Nov-2022
01-Sep-2023
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