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    Also known as: 100286-90-6, Irinotecan hcl, Topotecin, Campto, Camptothecin 11 hydrochloride, Camptosar
    Molecular Formula
    C33H39ClN4O6
    Molecular Weight
    623.1  g/mol
    InChI Key
    GURKHSYORGJETM-WAQYZQTGSA-N
    FDA UNII
    06X131E4OE
    Irinotecan Hydrochloride
    A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.
    1 2D Structure

    Irinotecan Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate;hydrochloride
    2.1.2 InChI
    InChI=1S/C33H38N4O6.ClH/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3;1H/t33-;/m0./s1
    2.1.3 InChI Key
    GURKHSYORGJETM-WAQYZQTGSA-N
    2.1.4 Canonical SMILES
    CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
    2.1.5 Isomeric SMILES
    CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    06X131E4OE
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 7 Ethyl 10 Hydroxycamptothecin

    2. 7-ethyl-10-hydroxycamptothecin

    3. Camptosar

    4. Camptothecin 11

    5. Camptothecin-11

    6. Cpt 11

    7. Cpt-11

    8. Cpt11

    9. Irinotecan

    10. Irrinotecan

    11. Nk012 Compound

    12. Sn 38

    13. Sn 38 11

    14. Sn-38

    15. Sn-38-11

    16. Sn3811

    2.3.2 Depositor-Supplied Synonyms

    1. 100286-90-6

    2. Irinotecan Hcl

    3. Topotecin

    4. Campto

    5. Camptothecin 11 Hydrochloride

    6. Camptosar

    7. Cpt 11

    8. Cpt-11

    9. Irinotecan (hydrochloride)

    10. Camptothecin 11

    11. U 101440e

    12. Chebi:5971

    13. (s)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate Hydrochloride

    14. Camptothecin Analog

    15. 06x131e4oe

    16. 7-ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxy Camptothecin Hydrochloride

    17. Nsc616348

    18. Nsc-616348

    19. Ncgc00095190-01

    20. Dsstox_cid_25953

    21. Dsstox_rid_81249

    22. Dsstox_gsid_45953

    23. [(19s)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate;hydrochloride

    24. Irinotecan Hydrochloride Anhydrous

    25. Cas-100286-90-6

    26. U-101440e

    27. Unii-06x131e4oe

    28. Irinotecan Hydrochloride [usan:jan]

    29. Mfcd01862255

    30. Irinotecanhydrochloride

    31. Cpt-11 Hydrochloride

    32. Irinotecan Monohydrochloride

    33. Schembl4033

    34. Camptosar (tn) (pharmacia)

    35. (s)-[1,4'-bipiperidine]-1'-carboxylic Acid, 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Ester Hydrochloride

    36. Spectrum1505821

    37. Chembl541887

    38. Dtxsid6045953

    39. Hms1922j04

    40. Pharmakon1600-01505821

    41. Amy24895

    42. Bcp17234

    43. Irinotecan Hydrochloride (anhydrous)

    44. Tox21_111479

    45. Hy-16562a

    46. Nsc759878

    47. S5026

    48. Akos015901921

    49. Tox21_111479_1

    50. Ccg-213561

    51. Irinotecan Hydrochloride [who-dd]

    52. Ncgc00095190-02

    53. Ncgc00178697-04

    54. (1,4'-bipiperidine)-1'-carboxylic Acid, (4s)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl Ester, Monohydrochloride

    55. (1,4'-bipiperidine)-1'-carboxylic Acid, 3,4,12,14-tetrahydro-4,11-diethyl-4-hydroxy-3,4-dioxo-1h-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl Ester, Monohydrochloride, (s)-

    56. Ac-28335

    57. As-13304

    58. I0714

    59. Irinotecan Hydrochloride Anhydrous [mi]

    60. Irinotecan Hydrochloride, Topoisomerase Inhibitor

    61. 286i906

    62. A897508

    63. Sr-01000763864

    64. Q-100016

    65. Sr-01000763864-3

    66. Q27106952

    67. Z1550648758

    68. (+)-7-ethyl-10-hydroxycamptothecine 10-(1,4'-bipiperidine)-1'-carboxylate, Monohydrochloride

    69. (1,4'-bipiperidine)-1'-carboxylic Acid, (4s)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl Ester, Hydrochloride (1:1)

    70. (19s)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl [1,4'-bipiperidine]-1'-carboxylate Hydrochloride

    71. (4s)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylic Acid Ester Hydrochloride

    72. (4s)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate Hydrochloride

    73. (s)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylatehydrochloride

    74. [(19s)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate Hydrochloride

    75. [1, 4,11-diethyl-3,4,12, 14-tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano[3',4':6,7] Indolizino[1,2-b]quinolin-9-yl Ester, Monohydrochloride (s)-

    76. [1,4'-bipiperidine]-1'-carboxylic Acid,(4s)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Ester, Monohydrochloride

    77. 1-[1-({[(4s)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl]oxy}carbonyl)piperidin-4-yl]piperidin-1-ium Chloride

    2.3.3 Other Synonyms

    1. Camptosar

    2. Campto

    3. Irinotecan

    4. Hy-16562

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 623.1 g/mol
    Molecular Formula C33H39ClN4O6
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count5
    Exact Mass622.2558127 g/mol
    Monoisotopic Mass622.2558127 g/mol
    Topological Polar Surface Area113 Ų
    Heavy Atom Count44
    Formal Charge0
    Complexity1200
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameIrinotecan hydrochloride
    Drug LabelIrinotecan hydrochloride injection is an antineoplastic agent of the topoisomerase I inhibitor class. Irinotecan hydrochloride was clinically investigated as CPT-11. Irinotecan hydrochloride injection is supplied as a sterile, pale yellow, clear, aqu...
    Active IngredientIrinotecan hydrochloride
    Dosage FormInjectable
    Routeinjection; Injection
    Strength20mg/ml; 100mg/5ml (20mg/ml); 500mg/25ml (20mg/ml); 100mg/5ml; 40mg/2ml (20mg/ml)
    Market StatusPrescription
    CompanyPliva Lachema; Hospira; Teva Parenteral; Fresenius Kabi Oncol; Accord Hlthcare; Jiangsu Hengrui Med; Hikma Farmaceutica; Teva Pharms Usa; Cipla; Hisun Pharm Hangzhou; Sun Pharma Global; Actavis Elizabeth; Emcure Pharms; Mustafa Nevzat Ilac; Fresenius Kabi

    2 of 2  
    Drug NameIrinotecan hydrochloride
    Drug LabelIrinotecan hydrochloride injection is an antineoplastic agent of the topoisomerase I inhibitor class. Irinotecan hydrochloride was clinically investigated as CPT-11. Irinotecan hydrochloride injection is supplied as a sterile, pale yellow, clear, aqu...
    Active IngredientIrinotecan hydrochloride
    Dosage FormInjectable
    Routeinjection; Injection
    Strength20mg/ml; 100mg/5ml (20mg/ml); 500mg/25ml (20mg/ml); 100mg/5ml; 40mg/2ml (20mg/ml)
    Market StatusPrescription
    CompanyPliva Lachema; Hospira; Teva Parenteral; Fresenius Kabi Oncol; Accord Hlthcare; Jiangsu Hengrui Med; Hikma Farmaceutica; Teva Pharms Usa; Cipla; Hisun Pharm Hangzhou; Sun Pharma Global; Actavis Elizabeth; Emcure Pharms; Mustafa Nevzat Ilac; Fresenius Kabi

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Topoisomerase I Inhibitors

    Compounds that inhibit the activity of DNA TOPOISOMERASE I. (See all compounds classified as Topoisomerase I Inhibitors.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Topoisomerase Inhibitors [MoA]; Topoisomerase Inhibitor [EPC]

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    04

    Pliva-lachema As

    Croatia
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    Medlab Asia & Asia Health
    Not Confirmed

    GDUFA

    DMF Review : Complete

    Rev. Date : 2012-11-23

    Pay. Date : 2012-11-09

    DMF Number : 19050

    Submission : 2005-12-20

    Status : Active

    Type : II

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    05

    Medlab Asia & Asia Health
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    05

    Polymed Therapeutics Inc

    U.S.A
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    Medlab Asia & Asia Health
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 18969

    Submission : 2005-10-30

    Status : Inactive

    Type : II

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    06

    Medlab Asia & Asia Health
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    06

    Sai Phytoceuticals Pvt Ltd

    India
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    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 19661

    Submission : 2006-07-27

    Status : Inactive

    Type : II

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    07

    Scinopharm Taiwan Ltd

    Taiwan

    USDMF

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    Not Confirmed

    07

    Scinopharm Taiwan Ltd

    Taiwan
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    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 17312

    Submission : 2004-04-20

    Status : Active

    Type : II

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    08

    Medlab Asia & Asia Health
    Not Confirmed

    08

    Sun Pharmaceutical Industries Ltd

    India
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    Medlab Asia & Asia Health
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 20195

    Submission : 2007-01-12

    Status : Inactive

    Type : II

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    09

    Terumo Corp

    Japan

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    Medlab Asia & Asia Health
    Not Confirmed

    09

    Terumo Corp

    Japan
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    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 19222

    Submission : 2006-03-06

    Status : Inactive

    Type : II

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    10

    Yakult Honsha Co Ltd

    Japan

    USDMF

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    Medlab Asia & Asia Health
    Not Confirmed

    10

    Yakult Honsha Co Ltd

    Japan
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    Medlab Asia & Asia Health
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 8553

    Submission : 1990-05-02

    Status : Inactive

    Type : II

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    API Reference Price

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EMIRATES","quantity":"9.00","actualQuantity":"9","unit":"KGS","unitRateFc":"15273.3","totalValueFC":"135616.8","currency":"USD","unitRateINR":1266156.5700000001,"date":"01-Oct-2024","totalValueINR":"11395409.13","totalValueInUsd":"135616.8","indian_port":"Bombay Air","hs_no":"29349990","bill_no":"4502276","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"UNITED ARAB EMIRATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"A-2,419, CELEBRATION CITY CENTER,,, AHMEDABAD,GUJARAT","customerAddress":""},{"dataSource":"API Import","activeIngredients":"IRINOTECAN HYDROCHLORIDE TRIHYDRATE","year":"2021","qtr":"Q2","strtotime":1620412200,"product":"IRINOTECAN HYDROCHLORIDE TRIHYDRATE,BATCH NO-20002ER12B,DOM05\/2020,DOE 05\/2023","address":"B-310, SOM DATT CHAMBERS, 1,BHIKAJI CAMA PLACE,","city":"NEW DELHI","supplier":"OLON S.P.A","supplierCountry":"ITALY","foreign_port":"MILAN","customer":"FRESENIUS SE & CO. 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HIGHWAY, THALTEJ","city":"AHMEDABAD,GUJARAT","supplier":"QILU PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"#N\/A","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"6.08","actualQuantity":"6076","unit":"GMS","unitRateFc":"19","totalValueFC":"116693.9","currency":"USD","unitRateINR":"1430.7","date":"31-Jan-2022","totalValueINR":"8692933.2","totalValueInUsd":"116693.9","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"7313634","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"CORPORATE HOUSE, NR. SOLA BRIDGE,, S.G. HIGHWAY, THALTEJ"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1657823400,"product":"IRINOTECAN HYDROCHLORIDE TRIHYDRATE BATCH NO 70495RA009","address":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ","city":"TAL- SANAND, DIST- AHMEDABAD","supplier":"SCINOPHARM TAIWAN, LTD","supplierCountry":"TAIWAN","foreign_port":"TAIPEI","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"48724.5","totalValueFC":"734392.8","currency":"USD","unitRateINR":"3893091.5","date":"15-Jul-2022","totalValueINR":"58396373","totalValueInUsd":"734392.8","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29419090","bill_no":"1002860","productDescription":"API","marketType":"REGULATED MARKET","country":"TAIWAN","selfForZScoreResived":"Pharma Grade","supplierPort":"TAIPEI","supplierAddress":"N\/A","customerAddress":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1663266600,"product":"IRINOTECAN HYDROCHLORIDE TRIHYDRATE JP BATCH NO 70495AA587","address":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ","city":"TAL- SANAND, DIST- AHMEDABAD","supplier":"SCINO PHARMA TAIWAN LTD","supplierCountry":"TAIWAN","foreign_port":"TAIPEI","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"37770.2","totalValueFC":"189461.2","currency":"USD","unitRateINR":"3036723.8","date":"16-Sep-2022","totalValueINR":"15183619","totalValueInUsd":"189461.2","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29339990","bill_no":"1003838","productDescription":"API","marketType":"REGULATED MARKET","country":"TAIWAN","selfForZScoreResived":"Pharma Grade","supplierPort":"TAIPEI","supplierAddress":"N\/A","customerAddress":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1674066600,"product":"IRINOTECAN HYDROCHLORIDE TRIHYDRATE EP\/BP\/IP\/USP\/PH.EUR","address":"CORPORATE HOUSE, NR. 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    12-Jan-2021
    01-Oct-2024
    KGS
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

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    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    INTERMEDIATES SUPPLIERS

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    01

    Cohance Lifesciences

    India
    Antibody Engineering
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    Virtual BoothCohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

    (S)-8-Ethyl-8-hydroxy-2,3,5,8-tetrahydro-6-oxa-3a-...

    CAS Number : 110351-94-5

    End Use API : Irinotecan Hydrochloride

    About The Company : Cohance Lifesciences is a leading CDMO and API platform, offering products and services across all phases of a molecule’s lifecycle from development to commer...

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    Cohance Lifesciences

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    Virtual BoothCohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

    2’-Amino-5’-hydroxypropiophenone

    CAS Number : 35364-15-9

    End Use API : Irinotecan Hydrochloride

    About The Company : Cohance Lifesciences is a leading CDMO and API platform, offering products and services across all phases of a molecule’s lifecycle from development to commer...

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    03

    Cohance Lifesciences

    India
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    Virtual BoothCohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

    7-Ethyl-10-hydroxycamptothecin (SN-38)

    CAS Number : 86639-52-3

    End Use API : Irinotecan Hydrochloride

    About The Company : Cohance Lifesciences is a leading CDMO and API platform, offering products and services across all phases of a molecule’s lifecycle from development to commer...

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    Cohance Lifesciences

    India
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    Virtual BoothCohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

    2’-Amino-5’-hydroxypropiophenone (AHP)

    CAS Number : 35364-15-9

    End Use API : Irinotecan Hydrochloride

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    Tagoor Laboratories

    India
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    Virtual BoothTagoor's product development expertise, backed by our comprehensive understanding of the processes, helps us offer high-quality APIs.

    4-Piperidinopiperidine

    CAS Number : 4897-50-1

    End Use API : Irinotecan Hydrochloride

    About The Company : Tagoor Laboratories, established in 2018, is a part of the Tagoor Group. It specializes in providing APIs, advanced intermediates and key starting materials for...

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    Tagoor Laboratories

    India
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    Virtual BoothTagoor's product development expertise, backed by our comprehensive understanding of the processes, helps us offer high-quality APIs.

    4-Piperidinopiperidine

    CAS Number : 4897-50-1

    End Use API : Irinotecan Hydrochloride

    About The Company : Tagoor Laboratories, established in 2018, is a part of the Tagoor Group. It specializes in providing APIs, advanced intermediates and key starting materials for...

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    Tagoor Laboratories

    India
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    Virtual BoothTagoor's product development expertise, backed by our comprehensive understanding of the processes, helps us offer high-quality APIs.

    4-Piperidinylpiperidine dihydrochloride

    CAS Number : 4876-60-2

    End Use API : Irinotecan Hydrochloride

    About The Company : Tagoor Laboratories, established in 2018, is a part of the Tagoor Group. It specializes in providing APIs, advanced intermediates and key starting materials for...

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    Tagoor Laboratories

    India
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    Virtual BoothTagoor's product development expertise, backed by our comprehensive understanding of the processes, helps us offer high-quality APIs.

    4-Piperidinylpiperidine dihydrochloride

    CAS Number : 4876-60-2

    End Use API : Irinotecan Hydrochloride

    About The Company : Tagoor Laboratories, established in 2018, is a part of the Tagoor Group. It specializes in providing APIs, advanced intermediates and key starting materials for...

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    09

    Allchem Laboratories

    India
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    Allchem Laboratories

    India
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    4-Piperidinopiperidine

    CAS Number : 4897-50-1

    End Use API : Irinotecan Hydrochloride

    About The Company : Established in 2003 with small pilot plant and came in to commercial production in 2013 in the name of Allchem Laboratories, it is an independent privately owne...

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    10

    Chengdu Yazhong Bio-pharmaceutical

    China
    Antibody Engineering
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    Chengdu Yazhong Bio-pharmaceutical

    China
    Antibody Engineering
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    10-Hydroxycamptothecin

    CAS Number : 19685-09-7

    End Use API : Irinotecan Hydrochloride

    About The Company : Chengdu Yazhong Bio-pharmaceutical Co., Ltd., founded in 2002, is a leading company with plant extracts, APIs and medical intermediates. Our company is equipped...

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    01

    AUROBINDO PHARMA ITALIA Srl

    India
    AES 2024
    Not Confirmed
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    AUROBINDO PHARMA ITALIA Srl

    India
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    AES 2024
    Not Confirmed
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    Regulatory Info :

    Registration Country : Italy

    Irinotecan

    Brand Name : Irinotecan

    Dosage Form : Irinotecan 500Mg 25Ml 1 Units Parenteral Use

    Dosage Strength : 1 vial EV 500 mg 25 ml 20 mg/ml

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Italy

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    02

    Fresenius Kabi Oncology Plc

    Sweden
    AES 2024
    Not Confirmed
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    Sweden
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    AES 2024
    Not Confirmed
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    Regulatory Info :

    Registration Country : Sweden

    irinotecan

    Brand Name : Irinokabi

    Dosage Form : CONCENTRATE FOR SOLUTION FOR INFUSION

    Dosage Strength : 20 MG / ML

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Sweden

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    03

    The Fresenius Kabi Oncology Plc

    India
    AES 2024
    Not Confirmed
    arrow

    The Fresenius Kabi Oncology Plc

    India
    arrow
    AES 2024
    Not Confirmed
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    Regulatory Info :

    Registration Country : Norway

    Irinotecan

    Brand Name : Irinokabi

    Dosage Form : Concentrate to the infusion fluid

    Dosage Strength : 20 mg/ml

    Packaging : Hood glass

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Norway

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    04

    The Fresenius Kabi Oncology Plc

    India
    AES 2024
    Not Confirmed
    arrow

    The Fresenius Kabi Oncology Plc

    India
    arrow
    AES 2024
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
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    Regulatory Info :

    Registration Country : Norway

    Irinotecan

    Brand Name : Irinotecan The Fresenius Kabi

    Dosage Form : Concentrate to the infusion fluid, resolution

    Dosage Strength : 20 mg/ml

    Packaging : Hood glass

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Norway

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    05

    HOSPIRA ITALIA Srl

    U.S.A
    AES 2024
    Not Confirmed
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    HOSPIRA ITALIA Srl

    U.S.A
    arrow
    AES 2024
    Not Confirmed
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    Regulatory Info :

    Registration Country : Italy

    Irinotecan

    Brand Name : Irinotecan

    Dosage Form : Irinotecan 100Mg 5Ml 1 Units Parenteral Use

    Dosage Strength : 1 vial EV 100 mg 5 ml 20 mg/ml

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Italy

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    06

    Labatec Pharma SA

    Switzerland
    AES 2024
    Not Confirmed
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    Switzerland
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    AES 2024
    Not Confirmed
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    Regulatory Info :

    Registration Country : Switzerland

    Irinotecani Hydrochloridum Trihydricum

    Brand Name : Irinotecan Labatec

    Dosage Form : Inf Conc

    Dosage Strength : 40mg/2ml

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    07

    Labatec Pharma SA

    Switzerland
    AES 2024
    Not Confirmed
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    Labatec Pharma SA

    Switzerland
    arrow
    AES 2024
    Not Confirmed
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    Regulatory Info :

    Registration Country : Switzerland

    Irinotecani Hydrochloridum Trihydricum

    Brand Name : Irinotecan Labatec

    Dosage Form : Inf Conc

    Dosage Strength : 300mg/15ml

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    08

    Pfizer AG

    U.S.A
    AES 2024
    Not Confirmed
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    Pfizer AG

    U.S.A
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    AES 2024
    Not Confirmed
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    Regulatory Info :

    Registration Country : Switzerland

    Irinotecani Hydrochloridum Trihydricum

    Brand Name : Campto

    Dosage Form : Inf Konz

    Dosage Strength : 100mg/5ml

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    09

    Teva Pharma AG

    Israel
    AES 2024
    Not Confirmed
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    Teva Pharma AG

    Israel
    arrow
    AES 2024
    Not Confirmed
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    Regulatory Info :

    Registration Country : Switzerland

    Irinotecani Hydrochloridum Trihydricum

    Brand Name : Irinotecan-Teva liquid

    Dosage Form : Inf Conc

    Dosage Strength : 100mg/5ml

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    10

    Mylan Hospital AS

    U.S.A
    AES 2024
    Not Confirmed
    arrow

    Mylan Hospital AS

    U.S.A
    arrow
    AES 2024
    Not Confirmed
    • fda
    • EDQM
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    Regulatory Info :

    Registration Country : Sweden

    irinotecan

    Brand Name : Irinotecan Mylan

    Dosage Form : CONCENTRATE FOR SOLUTION FOR INFUSION

    Dosage Strength : 20 MG / ML

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Sweden

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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - INJECTABLE;INJECTION - 100MG/5ML (20...DOSAGE - INJECTABLE;INJECTION - 100MG/5ML (20MG/ML)

    USFDA APPLICATION NUMBER - 20571

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    DOSAGE - INJECTABLE;INJECTION - 300MG/15ML (2...DOSAGE - INJECTABLE;INJECTION - 300MG/15ML (20MG/ML)

    USFDA APPLICATION NUMBER - 20571

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    DOSAGE - INJECTABLE;INJECTION - 40MG/2ML (20M...DOSAGE - INJECTABLE;INJECTION - 40MG/2ML (20MG/ML)

    USFDA APPLICATION NUMBER - 20571

    read-more

    DOSAGE - INJECTABLE, LIPOSOMAL;INTRAVENOUS - ...DOSAGE - INJECTABLE, LIPOSOMAL;INTRAVENOUS - EQ 43MG BASE/10ML (EQ 4.3MG BASE/ML)

    USFDA APPLICATION NUMBER - 207793

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    01

    Brand Name : Irinotecan Actavis

    Ireland
    arrow
    Antibody Engineering
    Not Confirmed

    Brand Name : Irinotecan Actavis

    Ireland
    arrow
    Antibody Engineering
    Not Confirmed

    Actavis Group hf.

    Irinotecan Hydrochloride

    Dosage Form : Concentrate to the infusion flui...

    Dosage Strength : 20 mg/ml

    Price Per Pack (Euro) : 85.008

    Published in :

    Country : Norway

    RX/OTC/DISCN :

    blank

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    02

    Brand Name : Irinotecan Actavis

    Ireland
    arrow
    Antibody Engineering
    Not Confirmed

    Brand Name : Irinotecan Actavis

    Ireland
    arrow
    Antibody Engineering
    Not Confirmed

    Actavis Group hf.

    Irinotecan Hydrochloride

    Dosage Form : Concentrate to the infusion flui...

    Dosage Strength : 20 mg/ml

    Price Per Pack (Euro) : 203.36

    Published in :

    Country : Norway

    RX/OTC/DISCN :

    blank

    Portfolio PDF

    Product Web Link

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    03

    Brand Name : Irinotecan Actavis

    Ireland
    arrow
    Antibody Engineering
    Not Confirmed

    Brand Name : Irinotecan Actavis

    Ireland
    arrow
    Antibody Engineering
    Not Confirmed

    Actavis Group hf.

    Irinotecan Hydrochloride

    Dosage Form : Concentrate to the infusion flui...

    Dosage Strength : 20 mg/ml

    Price Per Pack (Euro) : 600.59

    Published in :

    Country : Norway

    RX/OTC/DISCN :

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    04

    Brand Name : Irinotecan Actavis

    Ireland
    arrow
    Antibody Engineering
    Not Confirmed

    Brand Name : Irinotecan Actavis

    Ireland
    arrow
    Antibody Engineering
    Not Confirmed

    Actavis Group hf.

    Irinotecan Hydrochloride

    Dosage Form : Concentrate to the infusion flui...

    Dosage Strength : 20 mg/ml

    Price Per Pack (Euro) : 997.81

    Published in :

    Country : Norway

    RX/OTC/DISCN :

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

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    05

    Brand Name : Irinokabi

    India
    arrow
    Antibody Engineering
    Not Confirmed

    Brand Name : Irinokabi

    India
    arrow
    Antibody Engineering
    Not Confirmed

    The Fresenius Kabi Oncology Plc

    Irinotecan Hydrochloride

    Dosage Form : Concentrate to the infusion flui...

    Dosage Strength : 20 mg/ml

    Price Per Pack (Euro) : 85.008

    Published in :

    Country : Norway

    RX/OTC/DISCN :

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    06

    Brand Name : Irinokabi

    India
    arrow
    Antibody Engineering
    Not Confirmed

    Brand Name : Irinokabi

    India
    arrow
    Antibody Engineering
    Not Confirmed

    The Fresenius Kabi Oncology Plc

    Irinotecan Hydrochloride

    Dosage Form : Concentrate to the infusion flui...

    Dosage Strength : 20 mg/ml

    Price Per Pack (Euro) : 203.36

    Published in :

    Country : Norway

    RX/OTC/DISCN :

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    07

    Brand Name : Irinokabi

    India
    arrow
    Antibody Engineering
    Not Confirmed

    Brand Name : Irinokabi

    India
    arrow
    Antibody Engineering
    Not Confirmed

    The Fresenius Kabi Oncology Plc

    Irinotecan Hydrochloride

    Dosage Form : Concentrate to the infusion flui...

    Dosage Strength : 20 mg/ml

    Price Per Pack (Euro) : 600.59

    Published in :

    Country : Norway

    RX/OTC/DISCN :

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    08

    Brand Name : Irinokabi

    India
    arrow
    Antibody Engineering
    Not Confirmed

    Brand Name : Irinokabi

    India
    arrow
    Antibody Engineering
    Not Confirmed

    The Fresenius Kabi Oncology Plc

    Irinotecan Hydrochloride

    Dosage Form : Concentrate to the infusion flui...

    Dosage Strength : 20 mg/ml

    Price Per Pack (Euro) : 997.81

    Published in :

    Country : Norway

    RX/OTC/DISCN :

    blank

    Portfolio PDF

    Product Web Link

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    09

    Brand Name : Irinotecan Accord

    United Kingdom
    arrow
    Antibody Engineering
    Not Confirmed

    Brand Name : Irinotecan Accord

    United Kingdom
    arrow
    Antibody Engineering
    Not Confirmed

    Accord Healthcare Ltd.

    Irinotecan Hydrochloride

    Dosage Form : Concentrate to the infusion flui...

    Dosage Strength : 20 mg/ml

    Price Per Pack (Euro) : 85.008

    Published in :

    Country : Norway

    RX/OTC/DISCN :

    blank

    Portfolio PDF

    Product Web Link

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    10

    Brand Name : Irinotecan Accord

    United Kingdom
    arrow
    Antibody Engineering
    Not Confirmed

    Brand Name : Irinotecan Accord

    United Kingdom
    arrow
    Antibody Engineering
    Not Confirmed

    Accord Healthcare Ltd.

    Irinotecan Hydrochloride

    Dosage Form : Concentrate to the infusion flui...

    Dosage Strength : 20 mg/ml

    Price Per Pack (Euro) : 203.36

    Published in :

    Country : Norway

    RX/OTC/DISCN :

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

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    Market Place

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    Patents & EXCLUSIVITIES

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    US Exclusivities

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    IPSEN

    Contact Supplier
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      Flag France
      Virtual Booth Virtual Booth
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      IRINOTECAN HYDROCHLORIDE

      Portfolio PDF

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      ODE-463
      2031-02-13
      207793
      1
      blank

      01

      IPSEN

      IRINOTECAN HYDROCHLORIDE

      arrow
      Antibody Engineering
      Not Confirmed

      IPSEN

      France
      arrow
      Antibody Engineering
      Not Confirmed

      IRINOTECAN HYDROCHLORIDE

      Exclusivity Code : ODE-463

      Exclusivity Expiration Date : 2031-02-13

      Application Number : 207793

      Product Number : 1

      Exclusivity Details :

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      IPSEN

      Contact Supplier
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        IRINOTECAN HYDROCHLORIDE

        Portfolio PDF

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        I-932
        2027-02-13
        207793
        1
        blank

        02

        IPSEN

        IRINOTECAN HYDROCHLORIDE

        arrow
        Antibody Engineering
        Not Confirmed

        IPSEN

        France
        arrow
        Antibody Engineering
        Not Confirmed

        IRINOTECAN HYDROCHLORIDE

        Exclusivity Code : I-932

        Exclusivity Expiration Date : 2027-02-13

        Application Number : 207793

        Product Number : 1

        Exclusivity Details :

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        Health Canada Patents

        read-more
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        01

        Pfizer Canada Inc.

        Irinotecan Hydrochloride
        arrow
        Antibody Engineering
        Not Confirmed

        Pfizer Canada Inc.

        U.S.A
        arrow
        Antibody Engineering
        Not Confirmed

        Patent Expiration Date : 2015-10-11

        Date Granted : 2005-05-03

        Irinotecan Hydrochloride

        Brand Name : CAMPTOSAR

        Patent Number : 2202531

        Filing Date : 1995-10-11

        Strength per Unit : 20 mg / ml

        Dosage Form : Liquid

        Human Or VET : Human

        Route of Administration : Injectable

        Patent Expiration Date : 2015-10-11

        Date Granted : 2005-05-03

        blank

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        02

        Pfizer Canada Inc.

        Irinotecan Hydrochloride
        arrow
        Antibody Engineering
        Not Confirmed

        Pfizer Canada Inc.

        U.S.A
        arrow
        Antibody Engineering
        Not Confirmed

        Patent Expiration Date : 2018-07-27

        Date Granted : 2005-01-18

        Irinotecan Hydrochloride

        Brand Name : CAMPTOSAR

        Patent Number : 2294031

        Filing Date : 1998-07-27

        Strength per Unit : 20 mg / ml

        Dosage Form : Liquid

        Human Or VET : Human

        Route of Administration : Injectable

        Patent Expiration Date : 2018-07-27

        Date Granted : 2005-01-18

        blank

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        03

        Irinotecan Hydrochloride
        arrow
        Antibody Engineering
        Not Confirmed

        Country
        arrow
        Antibody Engineering
        Not Confirmed

        Patent Expiration Date : 2005-04-19

        Date Granted :

        Irinotecan Hydrochloride

        Brand Name :

        Patent Number : 1235415

        Filing Date :

        Strength per Unit :

        Dosage Form :

        Human Or VET :

        Route of Administration :

        Patent Expiration Date : 2005-04-19

        Date Granted :

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        REF. STANDARDS & IMPURITIES

        Upload your portfolio for free, ask us

        USP

        read-more
        read-more

        01

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        02

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        03

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        04

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        05

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        06

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        Others

        read-more
        read-more

        01

        Aozeal Certified Standards

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        02

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        Irinotecan Related Compound A (10 mg) ((S)-4-...

        CAS Number : 19685-09-7

        Quantity Per Vial : 10

        Sale Unit : mg

        Price : $835.00

        Details : Material Origin- Chemical Synthesis; USMCA- N...

        Monograph :

        Storage :

        Code/Batch No : Catalog #1347610 / R05430

        blank

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        03

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        Irinotecan Related Compound B (10 mg) ((S)-4,...

        CAS Number : 86639-52-3

        Quantity Per Vial : 10

        Sale Unit : mg

        Price : $775.00

        Details : Material Origin- Plant -Synthetic; USMCA- No;...

        Monograph :

        Storage :

        Code/Batch No : Catalog #1347631 / R107V0

        blank

        Portfolio PDF

        Product Web Link

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        Corporate PDF

        04

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        USP

        U.S.A
        arrow
        AES 2024
        Not Confirmed

        Irinotecan Related Compound C (10 mg)(11-Ethy...

        CAS Number :

        Quantity Per Vial : 10

        Sale Unit : mg

        Price : $814.00

        Details : Material Origin- Chemical Synthesis; USMCA- N...

        Monograph :

        Storage :

        Code/Batch No : Catalog #1347642 / R107W 0

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        Not Confirmed

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        AES 2024
        Not Confirmed

        Irinotecan Related Compound D (15 mg) ((R)-9-...

        CAS Number :

        Quantity Per Vial : 15

        Sale Unit : mg

        Price : $919.00

        Details : Material Origin- Chemical Synthesis; USMCA- N...

        Monograph :

        Storage :

        Code/Batch No : Catalog #1347653 / R11160

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        AES 2024
        Not Confirmed

        Irinotecan Related Compound E (15 mg) ((S)-4,...

        CAS Number : 78287-27-1

        Quantity Per Vial : 15

        Sale Unit : mg

        Price : $775.00

        Details : Material Origin- Chemical Synthesis; USMCA- N...

        Monograph :

        Storage :

        Code/Batch No : Catalog #1347664 / R124P0

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        AES 2024
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        AES 2024
        Not Confirmed

        Irinotecan Hydrochloride (100 mg)

        CAS Number : 136572-09-3

        Quantity Per Vial : 100

        Sale Unit : mg

        Price : $390.00

        Details : Material Origin- Chemical Synthesis; USMCA- N...

        Monograph :

        Storage :

        Code/Batch No : Catalog #1347609 / R10230

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