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Chemistry

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Also known as: Iron hydroxide oxide, Iron(3+);oxygen(2-);hydroxide, Iron hydroxide oxide nanoparticles / nanopowder, Iron oxide hydroxide, Iron hydroxide nanorods, Ferric oxy-hydroxide
Molecular Formula
FeHO2
Molecular Weight
88.85  g/mol
InChI Key
IEECXTSVVFWGSE-UHFFFAOYSA-M
FDA UNII
87PZU03K0K

Iron Sucrose
An antiferromagnetic material; constitutes the core of natural ferritin.
Ferric oxyhydroxide is a Phosphate Binder. The mechanism of action of ferric oxyhydroxide is as a Phosphate Chelating Activity.
1 2D Structure

Iron Sucrose

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
iron(3+);oxygen(2-);hydroxide
2.1.2 InChI
InChI=1S/Fe.H2O.O/h;1H2;/q+3;;-2/p-1
2.1.3 InChI Key
IEECXTSVVFWGSE-UHFFFAOYSA-M
2.1.4 Canonical SMILES
[OH-].[O-2].[Fe+3]
2.2 Other Identifiers
2.2.1 UNII
87PZU03K0K
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 5fe2o3.9h2o

2. Ferric Hydroxide Oxide

3. Ferric Hydroxide Oxide (feooh)

4. Ferric Oxy-hydroxide

5. Ferric Oxyhydroxide (feo2h)

6. Ferrihydrite

7. Iron Hydroxide Oxide (fe(oh)o)

8. Iron Hydroxide Oxide (feo(oh))

9. Iron(iii) Oxyhydroxide

2.3.2 Depositor-Supplied Synonyms

1. Iron Hydroxide Oxide

2. Iron(3+);oxygen(2-);hydroxide

3. Iron Hydroxide Oxide Nanoparticles / Nanopowder

4. Iron Oxide Hydroxide

5. Iron Hydroxide Nanorods

6. Ferric Oxy-hydroxide

7. Ferric Hydroxide [mi]

8. Dtxsid3042057

9. Ferric Oxyhydroxide (feo2h)

10. Ferric Hydroxide Oxide (feooh)

11. Db14695

12. Iron Hydroxide Oxide (feo(oh))

13. Iron Oxide Hydroxide, Aqueous Nanoparticle Dispersion, <5 Nm (dls), 20% Solids By Weight, Ph ~3, 99.5% Trace Metals Basis

2.3.3 Other Synonyms

1. Feojectin

2. Ferplex Ss

3. Ferrivenin

4. Iviron

5. Proferrin

6. Sucrofer

7. Iron Sugar

8. Saccharated Iron

9. Venoferrum

10. Fesin

11. Ferrum Vitis

12. Hippiron

13. Ferum Hausmann

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 88.85 g/mol
Molecular Formula FeHO2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass88.932590 g/mol
Monoisotopic Mass88.932590 g/mol
Topological Polar Surface Area2 Ų
Heavy Atom Count3
Formal Charge0
Complexity0
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameVelphoro
PubMed HealthSucroferric Oxyhydroxide (By mouth)
Drug ClassesPhosphate Binder
Active IngredientSucroferric oxyhydroxide
Dosage FormTablet, chewable
RouteOral
Strength500mg
Market StatusPrescription
CompanyVifor Fresenius

2 of 2  
Drug NameVelphoro
PubMed HealthSucroferric Oxyhydroxide (By mouth)
Drug ClassesPhosphate Binder
Active IngredientSucroferric oxyhydroxide
Dosage FormTablet, chewable
RouteOral
Strength500mg
Market StatusPrescription
CompanyVifor Fresenius

5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Active Moiety
FERRIC OXYHYDROXIDE
5.1.2 FDA UNII
87PZU03K0K
5.1.3 Pharmacological Classes
Mechanisms of Action [MoA] - Phosphate Chelating Activity

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15-Feb-2021
19-Feb-2025
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Looking for 20344-49-4 / Sucroferric Oxyhydroxide API manufacturers, exporters & distributors?

Sucroferric Oxyhydroxide manufacturers, exporters & distributors 1

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API | Excipient name

Sucroferric Oxyhydroxide

Synonyms

Iron hydroxide oxide, Iron(3+);oxygen(2-);hydroxide, Iron hydroxide oxide nanoparticles / nanopowder, Iron oxide hydroxide, Iron hydroxide nanorods, Ferric oxy-hydroxide

Cas Number

20344-49-4

Unique Ingredient Identifier (UNII)

87PZU03K0K

About Sucroferric Oxyhydroxide

An antiferromagnetic material; constitutes the core of natural ferritin.

Iron Sucrose Manufacturers

A Iron Sucrose manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Iron Sucrose, including repackagers and relabelers. The FDA regulates Iron Sucrose manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Iron Sucrose API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Iron Sucrose manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Iron Sucrose Suppliers

A Iron Sucrose supplier is an individual or a company that provides Iron Sucrose active pharmaceutical ingredient (API) or Iron Sucrose finished formulations upon request. The Iron Sucrose suppliers may include Iron Sucrose API manufacturers, exporters, distributors and traders.

click here to find a list of Iron Sucrose suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Iron Sucrose USDMF

A Iron Sucrose DMF (Drug Master File) is a document detailing the whole manufacturing process of Iron Sucrose active pharmaceutical ingredient (API) in detail. Different forms of Iron Sucrose DMFs exist exist since differing nations have different regulations, such as Iron Sucrose USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Iron Sucrose DMF submitted to regulatory agencies in the US is known as a USDMF. Iron Sucrose USDMF includes data on Iron Sucrose's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Iron Sucrose USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Iron Sucrose suppliers with USDMF on PharmaCompass.

Iron Sucrose KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Iron Sucrose Drug Master File in Korea (Iron Sucrose KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Iron Sucrose. The MFDS reviews the Iron Sucrose KDMF as part of the drug registration process and uses the information provided in the Iron Sucrose KDMF to evaluate the safety and efficacy of the drug.

After submitting a Iron Sucrose KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Iron Sucrose API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Iron Sucrose suppliers with KDMF on PharmaCompass.

Iron Sucrose WC

A Iron Sucrose written confirmation (Iron Sucrose WC) is an official document issued by a regulatory agency to a Iron Sucrose manufacturer, verifying that the manufacturing facility of a Iron Sucrose active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Iron Sucrose APIs or Iron Sucrose finished pharmaceutical products to another nation, regulatory agencies frequently require a Iron Sucrose WC (written confirmation) as part of the regulatory process.

click here to find a list of Iron Sucrose suppliers with Written Confirmation (WC) on PharmaCompass.

Iron Sucrose NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Iron Sucrose as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Iron Sucrose API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Iron Sucrose as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Iron Sucrose and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Iron Sucrose NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Iron Sucrose suppliers with NDC on PharmaCompass.

Iron Sucrose GMP

Iron Sucrose Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Iron Sucrose GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Iron Sucrose GMP manufacturer or Iron Sucrose GMP API supplier for your needs.

Iron Sucrose CoA

A Iron Sucrose CoA (Certificate of Analysis) is a formal document that attests to Iron Sucrose's compliance with Iron Sucrose specifications and serves as a tool for batch-level quality control.

Iron Sucrose CoA mostly includes findings from lab analyses of a specific batch. For each Iron Sucrose CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Iron Sucrose may be tested according to a variety of international standards, such as European Pharmacopoeia (Iron Sucrose EP), Iron Sucrose JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Iron Sucrose USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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