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Chemistry

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Also known as: Isoetharine mesylate salt, 7279-75-6, Isoetarine mesilate, Isotharine mesylate, Isoetharine (mesylate), 4-[1-hydroxy-2-([1-methylethyl]amino)butyl]-1,2-benzenediol methanesulfonate
Molecular Formula
C14H25NO6S
Molecular Weight
335.42  g/mol
InChI Key
SOYAGMVKMXZVNZ-UHFFFAOYSA-N

Isoetharine
Adrenergic beta-2 agonist used as bronchodilator for emphysema, bronchitis and asthma.
1 2D Structure

Isoetharine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol;methanesulfonic acid
2.1.2 InChI
InChI=1S/C13H21NO3.CH4O3S/c1-4-10(14-8(2)3)13(17)9-5-6-11(15)12(16)7-9;1-5(2,3)4/h5-8,10,13-17H,4H2,1-3H3;1H3,(H,2,3,4)
2.1.3 InChI Key
SOYAGMVKMXZVNZ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCC(C(C1=CC(=C(C=C1)O)O)O)NC(C)C.CS(=O)(=O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Bronkometer

2. Etyprenalinum

3. Isoetarin

4. Isoetharine

5. Mesylate, Isoetharine

2.2.2 Depositor-Supplied Synonyms

1. Isoetharine Mesylate Salt

2. 7279-75-6

3. Isoetarine Mesilate

4. Isotharine Mesylate

5. Isoetharine (mesylate)

6. 4-[1-hydroxy-2-([1-methylethyl]amino)butyl]-1,2-benzenediol Methanesulfonate

7. Mls000069674

8. Nsc-759286

9. Isoetarine Mesilate; Isoetharine Mesylate

10. Smr000058457

11. 4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol;methanesulfonic Acid

12. Isoetharine Mesilate

13. Isoetharine Mesylate (usp)

14. Sr-01000000183

15. Bronkometer (tn)

16. Ncgc00017071-01

17. Cas-7279-75-6

18. Prestwick_1003

19. Opera_id_1465

20. Dsstox_cid_25571

21. Dsstox_rid_80968

22. Dsstox_gsid_45571

23. Mls001146940

24. Schembl212005

25. Regid_for_cid_23702

26. Chembl1201153

27. Dtxsid2045571

28. 5-propylthiophene-3-carboxylicacid

29. Hms1570e20

30. Hms2093j16

31. Hms2097e20

32. Hms2230f06

33. Hms3262g03

34. Hms3714e20

35. Pharmakon1600-01505977

36. Hy-b1481

37. Tox21_110768

38. Tox21_500671

39. Nsc759286

40. Akos015889242

41. Ccg-213584

42. Lp00671

43. Ncgc00016157-02

44. Ncgc00094032-01

45. Ncgc00261356-01

46. Cs-0013181

47. Eu-0100671

48. Sw197083-3

49. D04626

50. I 3639

51. Sr-01000000183-2

52. Sr-01000000183-4

53. Sr-01000000183-6

54. 4-(1-hydroxy-2-(isopropylamino)butyl)benzene-1,2-diol Methanesulfonate

55. 4-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-1,2-benzenediol Mesylate

2.3 Create Date
2005-06-29
3 Chemical and Physical Properties
Molecular Weight 335.42 g/mol
Molecular Formula C14H25NO6S
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass335.14025869 g/mol
Monoisotopic Mass335.14025869 g/mol
Topological Polar Surface Area136 Ų
Heavy Atom Count22
Formal Charge0
Complexity315
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adrenergic beta-2 Receptor Agonists

Compounds bind to and activate ADRENERGIC BETA-2 RECEPTORS. (See all compounds classified as Adrenergic beta-2 Receptor Agonists.)


Bronchodilator Agents

Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)


ABOUT THIS PAGE

Isoetharine Manufacturers

A Isoetharine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Isoetharine, including repackagers and relabelers. The FDA regulates Isoetharine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Isoetharine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Isoetharine Suppliers

A Isoetharine supplier is an individual or a company that provides Isoetharine active pharmaceutical ingredient (API) or Isoetharine finished formulations upon request. The Isoetharine suppliers may include Isoetharine API manufacturers, exporters, distributors and traders.

click here to find a list of Isoetharine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Isoetharine USDMF

A Isoetharine DMF (Drug Master File) is a document detailing the whole manufacturing process of Isoetharine active pharmaceutical ingredient (API) in detail. Different forms of Isoetharine DMFs exist exist since differing nations have different regulations, such as Isoetharine USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Isoetharine DMF submitted to regulatory agencies in the US is known as a USDMF. Isoetharine USDMF includes data on Isoetharine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Isoetharine USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Isoetharine suppliers with USDMF on PharmaCompass.

Isoetharine GMP

Isoetharine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Isoetharine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Isoetharine GMP manufacturer or Isoetharine GMP API supplier for your needs.

Isoetharine CoA

A Isoetharine CoA (Certificate of Analysis) is a formal document that attests to Isoetharine's compliance with Isoetharine specifications and serves as a tool for batch-level quality control.

Isoetharine CoA mostly includes findings from lab analyses of a specific batch. For each Isoetharine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Isoetharine may be tested according to a variety of international standards, such as European Pharmacopoeia (Isoetharine EP), Isoetharine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Isoetharine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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