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Chemistry

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Also known as: Propan-2-amine, 2-propanamine, 75-31-0, 2-aminopropane, Monoisopropylamine, 2-propylamine
Molecular Formula
C3H9N
Molecular Weight
59.11  g/mol
InChI Key
JJWLVOIRVHMVIS-UHFFFAOYSA-N
FDA UNII
P8W26T4MTD

Isopropylamine
1 2D Structure

Isopropylamine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
propan-2-amine
2.1.2 InChI
InChI=1S/C3H9N/c1-3(2)4/h3H,4H2,1-2H3
2.1.3 InChI Key
JJWLVOIRVHMVIS-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C)N
2.2 Other Identifiers
2.2.1 UNII
P8W26T4MTD
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-propylamine

2. 2-propylamine Hydrochloride

3. 2-propylamine Sulfite

2.3.2 Depositor-Supplied Synonyms

1. Propan-2-amine

2. 2-propanamine

3. 75-31-0

4. 2-aminopropane

5. Monoisopropylamine

6. 2-propylamine

7. Sec-propylamine

8. 1-methylethylamine

9. Isopropyl Amine

10. Isopropilamina

11. Propane, 2-amino-

12. 2-aminopropan

13. 2-amino-propaan

14. 2-amino-propano

15. Mfcd00008082

16. Nsc 62775

17. P8w26t4mtd

18. Chebi:15739

19. Nsc-62775

20. 2-propaneamine

21. Isopropilamina [italian]

22. Isopropylamin

23. 2-aminopropan [german]

24. 2-amino-propaan [dutch]

25. 2-amino-propano [italian]

26. Ccris 4318

27. Hsdb 804

28. Einecs 200-860-9

29. Un1221

30. Unii-p8w26t4mtd

31. Isopropylarnine

32. Isoproylamine

33. I-propylamine

34. Iso-propylamine

35. Isopropyl-amine

36. Ai3-15636

37. I-propyl Amine

38. Iso- Propylamine

39. Iso-propyl Amine

40. Propane-2-amine

41. 2-propyl Amine

42. Propan-2 -amine

43. Iso-propylamine Gas

44. Iprnh2

45. (1-methylethyl)amine

46. Isopropylamine Solution (70% Or Less)

47. I-prnh2

48. Isopropylamine, 97%

49. Isopropylamine, 99%

50. Iso-c3h7nh2

51. 2-amino-propane

52. Ec 200-860-9

53. Isopropylamine [mi]

54. Isopropylamine [fhfi]

55. Isopropylamine [hsdb]

56. Isopropylamine [inci]

57. Isopropylamine, >=99.5%

58. Chembl117080

59. Wln: Zy1&1

60. Monoisopropylamine Reagent Grade

61. Dtxsid2025682

62. Fema No. 4238

63. Isopropylamine, >=97.0% (gc)

64. Nsc62775

65. Str00028

66. Zinc8220693

67. Stl194288

68. Akos000119321

69. Un 1221

70. Ft-0611265

71. I0165

72. Isopropylamine, Anhydrous, Analytical Standard

73. Isopropylamine, Saj Special Grade, >=99.0%

74. C06748

75. Isopropylamine [un1221] [flammable Liquid]

76. A838376

77. Q420554

78. Isopropylamine (purified By Distillation From Glass)

79. F2190-0359

80. G4o

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 59.11 g/mol
Molecular Formula C3H9N
XLogP30.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass59.073499291 g/mol
Monoisotopic Mass59.073499291 g/mol
Topological Polar Surface Area26 Ų
Heavy Atom Count4
Formal Charge0
Complexity10.8
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Absorption, Distribution and Excretion

Following a single intravenous injection of (14)C-isopropylamine HCl of 0.3 mg/kg bw into male Wistar rats, radioactivity was rapidly eliminated from the body via the urine with a half-life of about 2 to 4 hr. Following a single intraperitoneal injection of a similar dose, 97% of the radioactivity was excreted in the urine, all being identified as isopropylamine, 1.2% in the feces, and 1% in exhaled air. In in vitro experiments in which isopropylamine was incubated with rat liver microsomes in the presence of a NADPH-generating system, more than 94% was recovered as unchanged compound. /Isopropylamine HCl/

Health Council of the Netherlands, Committee on Updating of Occupational Exposure Limits; Health-Based Reassessment of Administrative Occupational Exposure Limits: Isopropylamine p.4-5 (June 8, 2004). Available from, as of January 12, 2018: https://www.gezondheidsraad.nl/sites/default/files/0015122_0.pdf


In mongrel dogs intravenously infused with isopropylamine (0.25 mg/kg/min, 45 min), an initial rapid and a subsequent slow decline in plasma levels with half life times of 5 and 146 min, respectively, were observed. These values indicate redistribution of isopropylamine into a tissue compartment followed by a slow release into and elimination from the blood. Examinations of tissues 2 hours post-infusion showed highest tissue/plasma ratios (ranging from approximately 5-17) for the kidneys (medulla, cortex), the spleen, the liver, the adrenal glands, and the lungs while significant amounts were found in sections of the brains (ratios of about 3-3.5) and the heart (ratios: ca. 2-3.5) (Pri82).

Health Council of the Netherlands, Committee on Updating of Occupational Exposure Limits; Health-Based Reassessment of Administrative Occupational Exposure Limits: Isopropylamine p.4 (June 8, 2004). Available from, as of January 12, 2018: https://www.gezondheidsraad.nl/sites/default/files/0015122_0.pdf


... Studies on the disposition of isopropylamine indicated that there was significant accumulation of isopropylamine in all tissues as compared to plasma. ...

PMID:7086693 Privitera PJ et al; J Pharmacol Exp Ther 222 (1): 116-21 (1982)


4.2 Biological Half-Life

Following a single intravenous injection of (14)C-isopropylamine HCl of 0.3 mg/kg bw into male Wistar rats, radioactivity was rapidly eliminated from the body via the urine with a half-life of about 2 to 4 hr. /Isopropylamine HCl/

Health Council of the Netherlands, Committee on Updating of Occupational Exposure Limits; Health-Based Reassessment of Administrative Occupational Exposure Limits: Isopropylamine p.4 (June 8, 2004). Available from, as of January 12, 2018: https://www.gezondheidsraad.nl/sites/default/files/0015122_0.pdf


In mongrel dogs intravenously infused with isopropylamine (0.25 mg/kg/min, 45 min), an initial rapid and a subsequent slow decline in plasma levels with half life times of 5 and 146 min, respectively, were observed.

Health Council of the Netherlands, Committee on Updating of Occupational Exposure Limits; Health-Based Reassessment of Administrative Occupational Exposure Limits: Isopropylamine p.4 (June 8, 2004). Available from, as of January 12, 2018: https://www.gezondheidsraad.nl/sites/default/files/0015122_0.pdf


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Looking for 75-31-0 / Isopropylamine API manufacturers, exporters & distributors?

Isopropylamine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Isopropylamine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Isopropylamine manufacturer or Isopropylamine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Isopropylamine manufacturer or Isopropylamine supplier.

PharmaCompass also assists you with knowing the Isopropylamine API Price utilized in the formulation of products. Isopropylamine API Price is not always fixed or binding as the Isopropylamine Price is obtained through a variety of data sources. The Isopropylamine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Isopropylamine

Synonyms

Propan-2-amine, 2-propanamine, 75-31-0, 2-aminopropane, Monoisopropylamine, 2-propylamine

Cas Number

75-31-0

Unique Ingredient Identifier (UNII)

P8W26T4MTD

Isopropylamine Manufacturers

A Isopropylamine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Isopropylamine, including repackagers and relabelers. The FDA regulates Isopropylamine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Isopropylamine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Isopropylamine Suppliers

A Isopropylamine supplier is an individual or a company that provides Isopropylamine active pharmaceutical ingredient (API) or Isopropylamine finished formulations upon request. The Isopropylamine suppliers may include Isopropylamine API manufacturers, exporters, distributors and traders.

Isopropylamine GMP

Isopropylamine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Isopropylamine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Isopropylamine GMP manufacturer or Isopropylamine GMP API supplier for your needs.

Isopropylamine CoA

A Isopropylamine CoA (Certificate of Analysis) is a formal document that attests to Isopropylamine's compliance with Isopropylamine specifications and serves as a tool for batch-level quality control.

Isopropylamine CoA mostly includes findings from lab analyses of a specific batch. For each Isopropylamine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Isopropylamine may be tested according to a variety of international standards, such as European Pharmacopoeia (Isopropylamine EP), Isopropylamine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Isopropylamine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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