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Chemistry

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Also known as: 521-48-2, Isoxanthohumol(sophora), 7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one, Chembl492828, 7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one, (+/-)-isoxanthohumol
Molecular Formula
C21H22O5
Molecular Weight
354.4  g/mol
InChI Key
YKGCBLWILMDSAV-UHFFFAOYSA-N

Isoxanthohumol
isoxanthohumol(sophora) is a natural product found in Streptomyces, Humulus lupulus, and Sophora flavescens with data available.
1 2D Structure

Isoxanthohumol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
2.1.2 InChI
InChI=1S/C21H22O5/c1-12(2)4-9-15-16(23)10-19(25-3)20-17(24)11-18(26-21(15)20)13-5-7-14(22)8-6-13/h4-8,10,18,22-23H,9,11H2,1-3H3
2.1.3 InChI Key
YKGCBLWILMDSAV-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(=CCC1=C2C(=C(C=C1O)OC)C(=O)CC(O2)C3=CC=C(C=C3)O)C
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. 521-48-2

2. Isoxanthohumol(sophora)

3. 7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

4. Chembl492828

5. 7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one

6. (+/-)-isoxanthohumol

7. Unii-b3bxq4ezd6

8. 5-methylsophoraflavanone B

9. Schembl904557

10. Hy-n2584a

11. Chebi:171798

12. Isoxanthohumol, >=99% (hplc)

13. Isoxanthohumol, Analytical Standard

14. (2s)-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

15. Bcp23864

16. Bdbm50252521

17. Lmpk12140553

18. Smp2_000215

19. Ncgc00390429-01

20. 4',7-dihydroxy-5-methoxy-8-prenylflavanone

21. Cs-0064440

22. 4',7-dihydroxy-5-methoxy-8-c-prenylflavanone

23. Q6086616

24. Isoxanthohumol, Primary Pharmaceutical Reference Standard

25. 7-hydroxy-2-(4-hydroxy-phenyl)-5-methoxy-8-(3-methyl-but-2-enyl)-chroman-4-one

26. 7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)chroman-4-one

27. 4h-1-benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)-

28. 7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)-2,3-dihydro-4h-chromen-4-one #

2.3 Create Date
2005-03-28
3 Chemical and Physical Properties
Molecular Weight 354.4 g/mol
Molecular Formula C21H22O5
XLogP34.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass354.14672380 g/mol
Monoisotopic Mass354.14672380 g/mol
Topological Polar Surface Area76 Ų
Heavy Atom Count26
Formal Charge0
Complexity519
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

REF. STANDARDS & IMPURITIES

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ABOUT THIS PAGE

Isoxanthohumol Manufacturers

A Isoxanthohumol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Isoxanthohumol, including repackagers and relabelers. The FDA regulates Isoxanthohumol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Isoxanthohumol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Isoxanthohumol Suppliers

A Isoxanthohumol supplier is an individual or a company that provides Isoxanthohumol active pharmaceutical ingredient (API) or Isoxanthohumol finished formulations upon request. The Isoxanthohumol suppliers may include Isoxanthohumol API manufacturers, exporters, distributors and traders.

Isoxanthohumol GMP

Isoxanthohumol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Isoxanthohumol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Isoxanthohumol GMP manufacturer or Isoxanthohumol GMP API supplier for your needs.

Isoxanthohumol CoA

A Isoxanthohumol CoA (Certificate of Analysis) is a formal document that attests to Isoxanthohumol's compliance with Isoxanthohumol specifications and serves as a tool for batch-level quality control.

Isoxanthohumol CoA mostly includes findings from lab analyses of a specific batch. For each Isoxanthohumol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Isoxanthohumol may be tested according to a variety of international standards, such as European Pharmacopoeia (Isoxanthohumol EP), Isoxanthohumol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Isoxanthohumol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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