Find ITI214 manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

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CEP/COS Certifications

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KDMF

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NDC API

NDC API

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Chemistry

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Also known as: Lenrispodun, 1160521-50-5, Iti-214, Iti-214 free base, Iti-214f, Lenrispodun [usan]
Molecular Formula
C29H26FN7O
Molecular Weight
507.6  g/mol
InChI Key
BBIPVJCGIASXJB-PKTZIBPZSA-N
FDA UNII
3GBO34D1BE

ITI214
ITI-214 is under investigation in clinical trial NCT03489772 (Study of ITI-214 in Healthy Volunteers to Determine CNS Engagement).
1 2D Structure

ITI214

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(11R,15S)-5-anilino-4-[[4-(6-fluoropyridin-2-yl)phenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one
2.1.2 InChI
InChI=1S/C29H26FN7O/c1-35-28(38)25-26(31-20-7-3-2-4-8-20)36(34-27(25)37-23-11-5-10-22(23)33-29(35)37)17-18-13-15-19(16-14-18)21-9-6-12-24(30)32-21/h2-4,6-9,12-16,22-23,31H,5,10-11,17H2,1H3/t22-,23+/m1/s1
2.1.3 InChI Key
BBIPVJCGIASXJB-PKTZIBPZSA-N
2.1.4 Canonical SMILES
CN1C(=O)C2=C(N(N=C2N3C1=NC4C3CCC4)CC5=CC=C(C=C5)C6=NC(=CC=C6)F)NC7=CC=CC=C7
2.1.5 Isomeric SMILES
CN1C(=O)C2=C(N(N=C2N3C1=N[C@H]4[C@@H]3CCC4)CC5=CC=C(C=C5)C6=NC(=CC=C6)F)NC7=CC=CC=C7
2.2 Other Identifiers
2.2.1 UNII
3GBO34D1BE
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(4-(6-fluoropyridin-2-yl)benzyl)-5-methyl-3-(phenylamino)-5,6a,7,8,9,9a-hexahydrocyclopenta(4,5)imidazo(1,2-a)pyrazolo(4,3-e)pyrimidin-4-(2h)-one

2. Iti-214

2.3.2 Depositor-Supplied Synonyms

1. Lenrispodun

2. 1160521-50-5

3. Iti-214

4. Iti-214 Free Base

5. Iti-214f

6. Lenrispodun [usan]

7. Iti-214 (free Base)

8. 3gbo34d1be

9. Ic200214

10. Chembl3769414

11. Ic-200214

12. (11r,15s)-5-anilino-4-[[4-(6-fluoropyridin-2-yl)phenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one

13. Iti214 (free Base)

14. (11r,15s)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one

15. Cyclopent(4,5)imidazo(1,2-a)pyrazolo(4,3-e)pyrimidin-4(2h)-one, 2-((4-(6-fluoro-2-pyridinyl)phenyl)methyl)-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(phenylamino)-, (6ar,9as)-

16. Pde1-in-1

17. Lenrispodun [inn]

18. Unii-3gbo34d1be

19. Pde4 (r)-(-)-rolipram

20. Schembl10201342

21. Gtpl12003

22. Bcp16186

23. Bdbm50150119

24. Who 11635

25. Zinc142626599

26. Compound 3 [pmid: 26789933]

27. Cs-3621

28. Db15039

29. (6ar,9as)-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(phenylamino)-2-((4-(6-fluoropyridin-2-yl)phenyl)methyl)-cyclopent[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2h)-one

30. (6ar,9as)-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(phenylamino)-2-((4-(6-fluoropyridin-2-yl)phenyl)methyl)cyclopent[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2h)-one

31. Hy-12501

32. Iti-214 Free Base;iti 214 Free Base

33. J3.605.616i

34. A858329

35. Q27454893

36. (6ar,9as)-2-((4-(6-fluoro-2-pyridinyl)phenyl)methyl)-5,6a,7,8,9,9ahexahydro- 5-methyl-3-(phenylamino)cyclopent(4,5)imidazo(1,2-a)pyrazolo(4,3- E)pyrimidin-4(2h)-one

37. (6ar,9as)-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(phenylamino)-2-((4-(6-fluoropyridin-2-yl)phenyl)methyl)-cyclopent[4,5]imidazo-[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2h)-one

2.4 Create Date
2009-07-15
3 Chemical and Physical Properties
Molecular Weight 507.6 g/mol
Molecular Formula C29H26FN7O
XLogP35.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass507.21828664 g/mol
Monoisotopic Mass507.21828664 g/mol
Topological Polar Surface Area78.6 Ų
Heavy Atom Count38
Formal Charge0
Complexity903
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

ITI214 Manufacturers

A ITI214 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of ITI214, including repackagers and relabelers. The FDA regulates ITI214 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. ITI214 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

ITI214 Suppliers

A ITI214 supplier is an individual or a company that provides ITI214 active pharmaceutical ingredient (API) or ITI214 finished formulations upon request. The ITI214 suppliers may include ITI214 API manufacturers, exporters, distributors and traders.

ITI214 GMP

ITI214 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of ITI214 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right ITI214 GMP manufacturer or ITI214 GMP API supplier for your needs.

ITI214 CoA

A ITI214 CoA (Certificate of Analysis) is a formal document that attests to ITI214's compliance with ITI214 specifications and serves as a tool for batch-level quality control.

ITI214 CoA mostly includes findings from lab analyses of a specific batch. For each ITI214 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

ITI214 may be tested according to a variety of international standards, such as European Pharmacopoeia (ITI214 EP), ITI214 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (ITI214 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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