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Chemistry

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Also known as: Ivermectin, Dihydroavermectin b1a, 70288-86-7, 22,23-dihydroavermectin b1a, 70161-11-4, Ivermectin component b1a
Molecular Formula
C48H74O14
Molecular Weight
875.1  g/mol
InChI Key
AZSNMRSAGSSBNP-XPNPUAGNSA-N
FDA UNII
91Y2202OUW

Ivermectin
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
1 2D Structure

Ivermectin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
2.1.2 InChI
InChI=1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1
2.1.3 InChI Key
AZSNMRSAGSSBNP-XPNPUAGNSA-N
2.1.4 Canonical SMILES
CCC(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C
2.1.5 Isomeric SMILES
CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C
2.2 Other Identifiers
2.2.1 UNII
91Y2202OUW
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Eqvalan

2. Ivermectin

3. Ivomec

4. Mectizan

5. Mk 933

6. Mk-933

7. Mk933

8. Stromectol

2.3.2 Depositor-Supplied Synonyms

1. Ivermectin

2. Dihydroavermectin B1a

3. 70288-86-7

4. 22,23-dihydroavermectin B1a

5. 70161-11-4

6. Ivermectin Component B1a

7. 71827-03-7

8. Avermectin H2b1a

9. 5-o-demethyl-22,23-dihydroavermectin A1a

10. Chebi:63941

11. 91y2202ouw

12. (2ae,4e,5's,6s,6'r,7s,8e,11r,13r,15s,17ar,20r,20ar,20bs)-6'-[(2s)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2h,7h-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-o-(2,6-dideoxy-3-o-methyl-alpha-l-arabino-hexopyranosyl)-3-o-methyl-alpha-l-arabino-hexopyranoside

13. Mk-933

14. (1r,4s,5's,6r,6'r,8r,10e,12s,13s,14e,16e,20r,21r,24s)-6'-[(2s)-butan-2-yl]-21,24-dihydroxy-12-[(2r,4s,5s,6s)-5-[(2s,4s,5s,6s)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one

15. Ivermectin B1a-d2

16. C48h74o14

17. Unii-91y2202ouw

18. 22,23-dihydroavermectin B(1)a

19. Ncgc00163233-01

20. Ivermectin (ivm)

21. Ivm

22. Einecs 276-046-2

23. Dihydro Avermectin Bla

24. Brn 4643153

25. 22,23-dihydro-5-o-demethylavermectin A1a

26. H2b1a

27. Prestwick3_000156

28. Dsstox_cid_3181

29. Ivermectin (mk-0933)

30. Dsstox_rid_76909

31. Dsstox_gsid_23181

32. Bspbio_000292

33. Schembl312795

34. Bpbio1_000322

35. Chembl263291

36. Dtxsid8023181

37. Chebi:94551

38. Hms2089m09

39. Hms2095o14

40. Hms3712o14

41. Wca82703

42. Tox21_112034

43. Bdbm50409816

44. Mfcd30496678

45. S1351

46. Akos027470116

47. Ivermectin Component B1a [mi]

48. Zinc238808778

49. Zinc252286706

50. Ac-6014

51. Ccg-220156

52. Ncgc00186639-01

53. Ncgc00186639-03

54. As-14167

55. Bi166167

56. Cas-71827-03-7

57. Hy-126937

58. Ab00513813

59. Cs-0108408

60. 22,23-dihydroavermectin B1a; Ivermectin

61. Ab00513813-02

62. Ab00513813-03

63. Ab00513813_04

64. Avermectin A1a, 22,23-dihydro-5-o-demethyl-

65. 288i867

66. Ivermectin, Antibiotic For Culture Media Use Only

67. Q-201262

68. Brd-k24652731-001-02-7

69. Brd-k85554912-001-08-9

70. Q27132923

71. Ivermectin, British Pharmacopoeia (bp) Reference Standard

72. Ivermectin, European Pharmacopoeia (ep) Reference Standard

73. Ivermectin, United States Pharmacopeia (usp) Reference Standard

74. Ivermectin, Pharmaceutical Secondary Standard; Certified Reference Material

75. (2ae,4e,5's,6s,6'r,7s,8e,11r,13r,15s,17ar,20r,20ar,20bs)-6'-[(2s)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17

76. Clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-o-(2,6-dideoxy-3-o-methyl-alpha-l-arabino-hexopyranosyl)-3-o-methyl-alpha-l-arabino-hexopyranoside

2.4 Create Date
2005-11-20
3 Chemical and Physical Properties
Molecular Weight 875.1 g/mol
Molecular Formula C48H74O14
XLogP34.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count14
Rotatable Bond Count8
Exact Mass874.50785703 g/mol
Monoisotopic Mass874.50785703 g/mol
Topological Polar Surface Area170 Ų
Heavy Atom Count62
Formal Charge0
Complexity1680
Isotope Atom Count0
Defined Atom Stereocenter Count20
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count3
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Treatment of rosacea


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Antiparasitic Agents

Drugs used to treat or prevent parasitic infections. (See all compounds classified as Antiparasitic Agents.)


Insecticides

Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics. (See all compounds classified as Insecticides.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Pediculicide [EPC]; Antiparasitic [EPC]
5.3 ATC Code

D - Dermatologicals

D11 - Other dermatological preparations

D11A - Other dermatological preparations

D11AX - Other dermatologicals

D11AX22 - Ivermectin


P - Antiparasitic products, insecticides and repellents

P02 - Anthelmintics

P02C - Antinematodal agents

P02CF - Avermectines

P02CF01 - Ivermectin


NDC API

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IVERMECTIN

NDC Package Code : 73377-144

Start Marketing Date : 2021-08-13

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1g/g)

Marketing Category : BULK INGREDIENT FOR HUMAN P...

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IVERMECTIN

NDC Package Code : 77382-0110

Start Marketing Date : 1998-10-08

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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IVERMECTIN

NDC Package Code : 77382-0100

Start Marketing Date : 1998-10-08

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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IVERMECTIN

NDC Package Code : 71052-225

Start Marketing Date : 2019-12-24

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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IVERMECTIN

NDC Package Code : 71052-671

Start Marketing Date : 2021-04-06

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1g/g)

Marketing Category : BULK INGREDIENT

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IVERMECTIN

NDC Package Code : 62991-3195

Start Marketing Date : 2023-08-28

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1g/g)

Marketing Category : BULK INGREDIENT

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Medisca Inc

U.S.A
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Medisca Inc

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IVERMECTIN

NDC Package Code : 38779-2468

Start Marketing Date : 2021-01-11

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1g/g)

Marketing Category : BULK INGREDIENT

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IVERMECTIN

NDC Package Code : 51927-5152

Start Marketing Date : 2021-09-10

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT FOR HUMAN P...

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IVERMECTIN

NDC Package Code : 66405-0001

Start Marketing Date : 2004-02-18

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (25kg/25kg)

Marketing Category : BULK INGREDIENT

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IVERMECTIN

NDC Package Code : 10695-052

Start Marketing Date : 2019-03-11

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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Listed Suppliers

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Virtual BoothCentrient is a leading manufacturer of Beta-Lactam Antibiotics and a provider of next-generation Statins and Antifungals.

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Ivermectin

About the Company : Established in 1869, Centrient Pharmaceuticals is a global B2B leader in sustainable, enzymatic antibiotics, next-generation statins and anti-fungals. Together with tablets, capsul...

Established in 1869, Centrient Pharmaceuticals is a global B2B leader in sustainable, enzymatic antibiotics, next-generation statins and anti-fungals. Together with tablets, capsules and finished dosage forms, it manufactures and markets intermediates and active pharmaceutical ingredients (APIs). It is a pharmaceutical company with a clear purpose — to improve lives through innovative and sustainable manufacturing of medicines. Centrient is committed to ensuring quality, reliability and sustainability for its customers, partners and patients. Its vision is to be the leading, diversified and fully integrated partner for generics marketers.
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LGM Pharma

U.S.A
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About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.
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Suanfarma

Spain
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About the Company : Suanfarma founded in 1993, is a B2B life science partner committed to health & innovation by developing, manufacturing, & distributing high-quality APIs for the pharmaceutical indu...

Suanfarma founded in 1993, is a B2B life science partner committed to health & innovation by developing, manufacturing, & distributing high-quality APIs for the pharmaceutical industry innovatively & sustainably. Backed by a robust global network of 12 strategically located local offices, we cater to the needs of over 400 active customers in 70+ countries. At Suanfarma we offer our CDMO capacity for fermentation & chemical synthesis projects, offering a One Stop Shop service with a solid track record, & which allows us to achieve success in the development, scaling, manufacturing, & commercialization of an API, either innovative or generic.
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DKSH

Switzerland
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Virtual BoothDKSH is your trusted partner for companies looking to grow their business in Asia & beyond.

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About the Company : DKSH, founded with the goal of improving people's lives, assists businesses with market expansion and business growth in both existing and emerging markets. It has been fostering g...

DKSH, founded with the goal of improving people's lives, assists businesses with market expansion and business growth in both existing and emerging markets. It has been fostering growth for businesses in Asia and beyond for over 155 years. DKSH operates in 36 markets, is listed on the SIX Swiss Exchange, employs 33,100 specialists, and generated net sales of CHF 11.1 billion in 2021. It is the leading global distributor of innovative pharma ingredients for pharmaceutical synthesis and formulation. It offers a range of products, ranging from animal care products to packaging materials, intermediates to nutraceuticals, and APIs to excipients.
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Virtual BoothJai Radhe Sales is your partner for all your sourcing needs.

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About the Company : Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete ...

Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete sourcing solutions for pharmaceutical products from India, including technical and regulatory assistance. It believes in providing its customers with high-quality products at reasonable prices. It has always endeavored to achieve global standards in the field of pharmaceuticals and has carved out a niche for itself through new methods based on current market needs. Today, it has established itself as a truly global company, with exports to almost every continent.
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Virtual BoothAtman Pharmaceuticals: A One Stop Solution Provider to All Your API Needs.

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About the Company : Atman Pharmaceuticals is a fully integrated pharmaceutical company that has distinguished itself as a leader in Bulk Drugs (API) marketing both domestically in India and overseas. ...

Atman Pharmaceuticals is a fully integrated pharmaceutical company that has distinguished itself as a leader in Bulk Drugs (API) marketing both domestically in India and overseas. With a heritage spanning over 33 years and vast experience, we have earned a reputation for delivering high-quality and abundant services within the industry. Our emergence as prominent solution providers in the pharmaceutical business underscores our commitment to excellence.
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CHEMO

Spain
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CHEMO

Spain
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Ivermectin

About the Company : More than 35 years of dedication to quality, service and pursuit of excellence, CHEMO was founded by Hugo Sigman, M.D., and Silvia Gold, Biochemist, in Spain (Barcelona), in 1977, ...

More than 35 years of dedication to quality, service and pursuit of excellence, CHEMO was founded by Hugo Sigman, M.D., and Silvia Gold, Biochemist, in Spain (Barcelona), in 1977, and starts business activities trading with pharmaceutical raw materials. In the 80's, the company expanded its operations into the Industrial Business, developing and manufacturing active pharmaceutical ingredients (APIs) in Italy (Industriale Chimica) and in Spain (Quimica Sintetica). In the 90's, CHEMO starts developing and manufacturing high quality and technology finished dosage forms (FDFs).
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About the Company : Dalian Richon Chem. Co., Ltd is a high-tech enterprise professionally involved in research and development, manufacturing process and sales service of pharmaceutical intermediates ...

Dalian Richon Chem. Co., Ltd is a high-tech enterprise professionally involved in research and development, manufacturing process and sales service of pharmaceutical intermediates and APIs. It has passed ISO9001:2000 international quality management system certificate. Its business scope includes development and manufacturing of APIs and pharmaceutical intermediates, contract development and manufacturing for domestic and international pharmaceutical companies, technical consultation, service and transfer.
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Ivermectin

About the Company : HENGDIAN GROUP was established in 1975, till now it has become a transnational,conglomerate group and been one of the largest private-owned enterprises in China. The Pharmaceutical...

HENGDIAN GROUP was established in 1975, till now it has become a transnational,conglomerate group and been one of the largest private-owned enterprises in China. The Pharmaceutical & Chemical division has 3 sub-companies with over 3,000 employees of which over 30% are technicians; This division is mainly producing APIs, Agrochemical and Dyestuffs with related intermediates as well as other special chemicals. The group also focuses on CONTRACT MANUFACTURE service under GMP and confidential agreement with our clients.
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Hovione

Portugal
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Portugal
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Ivermectin

About the Company : Hovione is an international company with over 60 years of experience as a Contract Development and Manufacturing Organization (CDMO) with a fully integrated offering of services fo...

Hovione is an international company with over 60 years of experience as a Contract Development and Manufacturing Organization (CDMO) with a fully integrated offering of services for drug substance, drug product intermediate and drug product. The company has four FDA inspected sites. Hovione provides pharmaceutical customers services for the development and compliant manufacture of innovative drugs, including highly potent compounds, and customized product solution across the entire drug life cycle. In the inhalation area, Hovione offers a complete range of services, from API, formulation development and devices.
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API Reference Price

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THANE, MAHARASHTRA","supplier":"CHINA SINOPHARM INTERNATIONAL CORP.","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"DIPS BIOSCIENCE PRIVATE LIMITED","customerCountry":"INDIA","quantity":"81.60","actualQuantity":"81.6","unit":"KGS","unitRateFc":"104","totalValueFC":"8584.7","currency":"USD","unitRateINR":"8939.1","date":"20-Dec-2024","totalValueINR":"729430.63","totalValueInUsd":"8584.7","indian_port":"JNPT","hs_no":"29322090","bill_no":"7367098","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO.293 JIANGNING ROAD SHANGHAI 200041 CHINA SDNF CN","customerAddress":"101,GOVIND SMRUTHI, B\/H TONDWALKAR"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1734633000,"product":"IVERMECTIN IVERMECTIN","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"HEBEI VEYONG PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"5.22","actualQuantity":"5.22","unit":"KGS","unitRateFc":"104.3","totalValueFC":"550.8","currency":"USD","unitRateINR":"8966.3","date":"20-Dec-2024","totalValueINR":"46804","totalValueInUsd":"550.8","indian_port":"JNPT","hs_no":"29419090","bill_no":"7362756","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO. 68 GANJIANG ROAD, SHIJIAZHUANG HEBEI CHINA 052165 SDNF CN","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1734633000,"product":"IVERMECTIN IVERMECTIN","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"HEBEI VEYONG PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"6.90","actualQuantity":"6.9","unit":"KGS","unitRateFc":"104.3","totalValueFC":"728.1","currency":"USD","unitRateINR":"8966.3","date":"20-Dec-2024","totalValueINR":"61867.36","totalValueInUsd":"728.1","indian_port":"JNPT","hs_no":"29419090","bill_no":"7362756","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO. 68 GANJIANG ROAD, SHIJIAZHUANG HEBEI CHINA 052165 SDNF CN","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1734633000,"product":"IVERMECTIN IVERMECTIN","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"HEBEI VEYONG PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"10.50","actualQuantity":"10.5","unit":"KGS","unitRateFc":"104.3","totalValueFC":"1108","currency":"USD","unitRateINR":"8966.3","date":"20-Dec-2024","totalValueINR":"94145.98","totalValueInUsd":"1108","indian_port":"JNPT","hs_no":"29419090","bill_no":"7362756","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO. 68 GANJIANG ROAD, SHIJIAZHUANG HEBEI CHINA 052165 SDNF CN","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1734633000,"product":"IVERMECTIN IVERMECTIN","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"HEBEI VEYONG PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"90.00","actualQuantity":"90","unit":"KGS","unitRateFc":"104.3","totalValueFC":"9497.2","currency":"USD","unitRateINR":"8966.3","date":"20-Dec-2024","totalValueINR":"806965.5","totalValueInUsd":"9497.2","indian_port":"JNPT","hs_no":"29419090","bill_no":"7362756","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO. 68 GANJIANG ROAD, SHIJIAZHUANG HEBEI CHINA 052165 SDNF CN","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."}]
01-Jan-2021
20-Dec-2024
KGS
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

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FDF Dossiers

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01

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BIO Partnering at JPM
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  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Ivermectin

Brand Name :

Dosage Form : Injection

Dosage Strength : 1%

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya

02

BIO Partnering at JPM
Not Confirmed
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BIO Partnering at JPM
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IVERMECTIN B1A

Brand Name : IVOMEC PREMIX FOR SWINE

Dosage Form : DRUG PREMIX

Dosage Strength : 0.6%/W/W

Packaging : 5KG & 25KG

Approval Date :

Application Number : 1913085

Regulatory Info :

Registration Country : Canada

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03

BIO Partnering at JPM
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BIO Partnering at JPM
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IVERMECTIN

Brand Name : EQVALAN

Dosage Form : PASTE

Dosage Strength : 120MG/SYR

Packaging : 6.42G

Approval Date :

Application Number : 594431

Regulatory Info :

Registration Country : Canada

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04

Dong Bang Co., Ltd

South Korea
BIO Partnering at JPM
Not Confirmed
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Dong Bang Co., Ltd

South Korea
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BIO Partnering at JPM
Not Confirmed

Ivermectin

Brand Name : Antip

Dosage Form : Premix

Dosage Strength : 2G/KG

Packaging : 1KG, 5KG, 20KG

Approval Date :

Application Number :

Regulatory Info :

Registration Country : South Korea

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05

Galderma

Switzerland
BIO Partnering at JPM
Not Confirmed
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Galderma

Switzerland
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BIO Partnering at JPM
Not Confirmed

ivermectin

Brand Name : Soolantra

Dosage Form : CREAM

Dosage Strength : 10 MG / G

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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06

Hiral Labs

India
BIO Partnering at JPM
Not Confirmed
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Hiral Labs

India
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BIO Partnering at JPM
Not Confirmed

Ivermectin

Brand Name :

Dosage Form : Uncoated Tablet

Dosage Strength : 12mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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07

MarchVet

India
BIO Partnering at JPM
Not Confirmed
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MarchVet

India
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BIO Partnering at JPM
Not Confirmed

Ivermectin

Brand Name :

Dosage Form : Tablet

Dosage Strength : 5MG; 50MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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08

Merck & Co

U.S.A
BIO Partnering at JPM
Not Confirmed
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Merck & Co

U.S.A
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BIO Partnering at JPM
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IVERMECTIN

Brand Name : STROMECTOL

Dosage Form : TABLET;ORAL

Dosage Strength : 3MG

Packaging :

Approval Date : 1998-10-08

Application Number : 50742

Regulatory Info : RX

Registration Country : USA

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09

MSD INTL GMBH

Singapore
BIO Partnering at JPM
Not Confirmed
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MSD INTL GMBH

Singapore
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BIO Partnering at JPM
Not Confirmed

ivermectin

Brand Name : Stromectol

Dosage Form : tablet

Dosage Strength : 3 mg

Packaging : 4

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

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10

BIO Partnering at JPM
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BIO Partnering at JPM
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Ivermectin

Brand Name : Evermec

Dosage Form : Oral Solution/Suspension

Dosage Strength : 0.5%

Packaging : 500ML,1000ML

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - LOTION;TOPICAL - 0.5%

USFDA APPLICATION NUMBER - 202736

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DOSAGE - CREAM;TOPICAL - 1%

USFDA APPLICATION NUMBER - 206255

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ABOUT THIS PAGE

Ivermectin Manufacturers

A Ivermectin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ivermectin, including repackagers and relabelers. The FDA regulates Ivermectin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ivermectin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ivermectin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ivermectin Suppliers

A Ivermectin supplier is an individual or a company that provides Ivermectin active pharmaceutical ingredient (API) or Ivermectin finished formulations upon request. The Ivermectin suppliers may include Ivermectin API manufacturers, exporters, distributors and traders.

click here to find a list of Ivermectin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ivermectin USDMF

A Ivermectin DMF (Drug Master File) is a document detailing the whole manufacturing process of Ivermectin active pharmaceutical ingredient (API) in detail. Different forms of Ivermectin DMFs exist exist since differing nations have different regulations, such as Ivermectin USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Ivermectin DMF submitted to regulatory agencies in the US is known as a USDMF. Ivermectin USDMF includes data on Ivermectin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ivermectin USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Ivermectin suppliers with USDMF on PharmaCompass.

Ivermectin JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Ivermectin Drug Master File in Japan (Ivermectin JDMF) empowers Ivermectin API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Ivermectin JDMF during the approval evaluation for pharmaceutical products. At the time of Ivermectin JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Ivermectin suppliers with JDMF on PharmaCompass.

Ivermectin CEP

A Ivermectin CEP of the European Pharmacopoeia monograph is often referred to as a Ivermectin Certificate of Suitability (COS). The purpose of a Ivermectin CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Ivermectin EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Ivermectin to their clients by showing that a Ivermectin CEP has been issued for it. The manufacturer submits a Ivermectin CEP (COS) as part of the market authorization procedure, and it takes on the role of a Ivermectin CEP holder for the record. Additionally, the data presented in the Ivermectin CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Ivermectin DMF.

A Ivermectin CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Ivermectin CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Ivermectin suppliers with CEP (COS) on PharmaCompass.

Ivermectin NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Ivermectin as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Ivermectin API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Ivermectin as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Ivermectin and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Ivermectin NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Ivermectin suppliers with NDC on PharmaCompass.

Ivermectin GMP

Ivermectin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ivermectin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ivermectin GMP manufacturer or Ivermectin GMP API supplier for your needs.

Ivermectin CoA

A Ivermectin CoA (Certificate of Analysis) is a formal document that attests to Ivermectin's compliance with Ivermectin specifications and serves as a tool for batch-level quality control.

Ivermectin CoA mostly includes findings from lab analyses of a specific batch. For each Ivermectin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ivermectin may be tested according to a variety of international standards, such as European Pharmacopoeia (Ivermectin EP), Ivermectin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ivermectin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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