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1. En 141
2. En-141
3. En141
4. Josamycine
5. Kitasamycin A3
6. Leucomycin A3
7. Turimycin A5
8. Wilprafen
1. Leucomycin A3
2. Turimycin A5
3. Kitasamycin A3
4. Josamycine
5. Antibiotic Yl-704 A3
6. 16846-24-5
7. Josamicina
8. Josamycinum
9. Josamycine [inn-french]
10. Josamycinum [inn-latin]
11. Iosalide
12. Josamina
13. Josamicina [inn-spanish]
14. En-141
15. Yl-704 A3
16. Jomybel
17. Josacine
18. Leucomycin V 3-acetate 4b-(3-methylbutanoate)
19. Leucomycin V, 3-acetate 4b-(3-methylbutanoate)
20. Leucomycin V, 3-acetate 4(sup B)-(3-methylbutanoate)
21. Hv13hfs217
22. Leucomycin V, 3-acetate 4(sup Beta)-(3-methylbutanoate)
23. Jm
24. Chebi:31739
25. Mfcd00210320
26. En 141
27. Einecs 240-871-6
28. Unii-hv13hfs217
29. Ccris 8511
30. Nsc122223
31. Hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] 3-methylbutanoate
32. Josamycin [usan:inn:ban:jan]
33. Josamycin (tn)
34. [(2s,3s,4r,6s)-6-[(2r,3s,4r,5r,6s)-6-[[(4r,5s,6s,7r,9r,10r,11e,13e,16r)-4-acetyloxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-
35. St075007
36. Josamycin [inn]
37. Josamycin [jan]
38. Josamycin [mi]
39. Josamycin [usan]
40. Josamycin [mart.]
41. Josamycin [who-dd]
42. [(2s,3s,4r,6s)-6-[(2r,3s,4r,5r,6s)-6-[[(4r,5s,6s,7r,9r,10r,11e,13e,16r)-4-acetyloxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] 3-methylbutanoate
43. Stereoisomer Of 4-(acetyloxy)-6-((3,6-dideoxy-4-o-(2,6-dideoxy-3-c-methyl-4-o-(3-methyl-1-oxobutyl)-alpha-l-ribo-hexopyranosyl)-3-(dimethylamino)-beta-d-glucopyranosyl)oxy)-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-diene-7-acetaldehyde
44. Stereoisomer Of 7-(formylmethyl)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-6-yl 3,6-dideoxy-4-o-(2,6-dideoxy-3-c-methyl-alpha-l-ribo-hexopyranosyl)-3-(dimethylamino)-beta-d-glucopyranoside 4'-acetate 4''-isovalerate
45. Schembl132829
46. Leucomycin V 3-acetate 4(beta)-(3-methylbutanoate)
47. Chembl224436
48. Josamycin (jp17/usan/inn)
49. Josamycin [ep Monograph]
50. Josamycin, >=98.0% (uv)
51. Hy-b1920
52. S4421
53. Zinc96006021
54. Db01321
55. Stereoisomer Of 7-(formylmethyl)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-6-yl 3,6-dideoxy-4-o-(2,6-dideoxy-3-c-methyl-alpha-l-ribo-hexopyranosyl)-3-(dimethylamino)-beta-d-glucopyranoside 4'-acetate 4'-isovalerate
56. Cs-0013975
57. D01235
58. Leucomycin V 3-acetate 4(b)-(3-methylbutanoate)
59. Leucomycin V 3-acetate 4beta-(3-methylbutanoate)
60. Q423369
61. Sr-01000883731
62. En-141;kitasamycin A3;leucomycin A3;turimycin A5
63. Sr-01000883731-1
64. Josamycin, European Pharmacopoeia (ep) Reference Standard
65. Leucomycin V, 3-acetate 4(sup .beta.)-(3-methylbutanoate)
66. Josamycin For Peak Identification, European Pharmacopoeia (ep) Reference Standard
67. (2s,3s,4r,6s)-6-{[(2r,3s,4r,5r,6s)-6-{[(4r,5s,6s,7r,9r,10r,11e,13e,16r)-4-(acetyloxy)-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl 3-methylbutanoate
68. [(2s,3s,4r,6s)-6-[(2r,3s,4r,5r,6s)-6-[[(4r,5s,6s,7r,9r,10r,11e,13e,16r)-4-acetoxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyl-tetrahydropyran-3-yl]oxy-4-hydroxy-2,4-dimethyl-tetrahydropyran-3-yl] 3-methylbutanoate
69. 56689-45-3
70. 6-{6-[3-acetyloxy-13-hydroxy-2-methoxy-7,14-dimethyl-6-oxa-5-oxo-16-(2-oxoethyl)cyclohexadeca-9,11-dienyloxy]-4-(dimethylamino)-5-hydroxy-2-methylperhydro-2h-pyran-3-yloxy}-4-hydroxy-2,4-dimethylperhydro-2h-pyran-3-yl 3-methylbutanoate
71. Josamycin 10 Microg/ml In Acetonitrile. Short Expiry Date Due To Chemical Nature Of Component(s)
Molecular Weight | 828.0 g/mol |
---|---|
Molecular Formula | C42H69NO15 |
XLogP3 | 2.9 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 16 |
Rotatable Bond Count | 14 |
Exact Mass | 827.46672049 g/mol |
Monoisotopic Mass | 827.46672049 g/mol |
Topological Polar Surface Area | 206 Ų |
Heavy Atom Count | 58 |
Formal Charge | 0 |
Complexity | 1390 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 16 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 2 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
For the treatment of bacterial infections.
Josamycin is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
Anti-Bacterial Agents
Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)
J - Antiinfectives for systemic use
J01 - Antibacterials for systemic use
J01F - Macrolides, lincosamides and streptogramins
J01FA - Macrolides
J01FA07 - Josamycin
The mechanism of action of macrolides such as Josamycin is via inhibition of bacterial protein biosynthesis by binding reversibly to the subunit 50S of the bacterial ribosome, thereby inhibiting translocation of peptidyl tRNA. This action is mainly bacteriostatic, but can also be bactericidal in high concentrations. Macrolides tend to accumulate within leukocytes, and are therefore actually transported into the site of infection.
Shanghai Minbiotech is the leading producer of biopharmaceuticals and a variety of high-end generic & innovative drugs.
Certificate Number : CEP 2021-502 - Rev 01
Issue Date : 2024-07-01
Type : Chemical
Substance Number : 1983
Status : Valid
Registration Number : 217MF10599
Registrant's Address : 1-3-1 Kyobashi, Chuo-ku, Tokyo
Initial Date of Registration : 2005-09-14
Latest Date of Registration : --
Certificate Number : CEP 2021-502 - Rev 01
Status : Valid
Issue Date : 2024-07-01
Type : Chemical
Substance Number : 1983
Registration Number : 217MF10599
Registrant's Address : 1-3-1 Kyobashi, Chuo-ku, Tokyo
Initial Date of Registration : 2005-09-14
Latest Date of Registration : 2010-01-28
Shanghai Minbiotech is the leading producer of biopharmaceuticals and a variety of high-end generic & innovative drugs.
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Regulatory Info :
Registration Country : Italy
Brand Name : Ialide
Dosage Form : Josamycin 1.000Mg 12 Combined Oral Use
Dosage Strength : 12 cpr dispers 1 g
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Italy
Regulatory Info :
Registration Country : Italy
Brand Name : Ialide
Dosage Form : Josamycin 500Mg 12 Combined Oral Use
Dosage Strength : 12 cpr riv 500 mg
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Italy
Regulatory Info :
Registration Country : France
Brand Name :
Dosage Form : Taste Masked Pellets S...
Dosage Strength : 250MG
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : France
Packaging :
Regulatory Info :
Dosage : Taste Masked Pellets S...
Dosage Strength : 250MG
Brand Name :
Approval Date :
Application Number :
Registration Country : France
Regulatory Info :
Registration Country : France
Brand Name :
Dosage Form : Tablet
Dosage Strength : 500MG
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : France
Packaging :
Regulatory Info :
Dosage : Tablet
Dosage Strength : 500MG
Brand Name :
Approval Date :
Application Number :
Registration Country : France
Global Sales Information
Dosage Form : Josamycin 1.000Mg 12 Combined Or...
Dosage Strength : 12 cpr dispers 1 g
Price Per Pack (Euro) : 13.59
Published in :
Country : Italy
RX/OTC/DISCN : Class A
Dosage Form : Josamycin 500Mg 12 Combined Oral...
Dosage Strength : 12 cpr riv 500 mg
Price Per Pack (Euro) : 7.66
Published in :
Country : Italy
RX/OTC/DISCN : Class A
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REF. STANDARDS & IMPURITIES
Josamycin
CAS Number : 16846-24-5
Quantity Per Vial : 150 mg
Sale Unit : 1
Order Code : Y0000041
Batch No : 2
Price (€) : 79
Storage : -20°C ± 5°C
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