Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients & provides custom-made solutions.

Contact Supplier

AbbVie CDMO has been working with global companies to develop, manufacture & scale biopharmaceutical products.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

FINISHED DOSAGE FORMULATIONS

5 FDF Dossiers, 5 Europe

5 FDF Dossiers
5 Europe

MARKET PLACE

1 APIs

marketPlace
1 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 9005-34-9, 6-(2-carboxy-4,5-dihydroxy-6-methoxyoxan-3-yl)oxy-4,5-dihydroxy-3-methoxyoxane-2-carboxylic acid, Kaltostat, 3-((6-carboxy-3,4-dihydroxy-5-methoxytetrahydro-2h-pyran-2-yl)oxy)-4,5-dihydroxy-6-methoxytetrahydro-2h-pyran-2-carboxylic acid, Schembl10118904, Akos015915207

Molecular Formula

C₁₄H₂₂O₁₃

Molecular Weight

398.32 g/mol

InChI Key

GKFPPCXIBHQRQT-UHFFFAOYSA-N

Salts and esters of ALGINIC ACID that are used as HYDROGELS; DENTAL IMPRESSION MATERIALS, and as absorbent materials for surgical dressings (BANDAGES, HYDROCOLLOID). They are also used to manufacture MICROSPHERES and NANOPARTICLES for DIAGNOSTIC REAGENT KITS and DRUG DELIVERY SYSTEMS.

1 2D Structure

Kaltostat

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

6-(2-carboxy-4,5-dihydroxy-6-methoxyoxan-3-yl)oxy-4,5-dihydroxy-3-methoxyoxane-2-carboxylic acid

2.1.2 InChI

InChI=1S/C14H22O13/c1-23-7-3(15)6(18)14(27-9(7)11(19)20)25-8-4(16)5(17)13(24-2)26-10(8)12(21)22/h3-10,13-18H,1-2H3,(H,19,20)(H,21,22)

2.1.3 InChI Key

GKFPPCXIBHQRQT-UHFFFAOYSA-N

2.1.4 Canonical SMILES

COC1C(C(C(OC1C(=O)O)OC2C(C(C(OC2C(=O)O)OC)O)O)O)O

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Alginate

2. Alginate, Barium

3. Alginate, Calcium

4. Alginate, Copper

5. Alginate, Potassium

6. Alginate, Sodium

7. Alginate, Sodium Calcium

8. Alginates

9. Alginic Acid, Barium Salt

10. Alginic Acid, Calcium Salt

11. Alginic Acid, Copper Salt

12. Alginic Acid, Potassium Salt

13. Alginic Acid, Sodium Salt

14. Alloid G

15. Barium Alginate

16. Calcium Alginate

17. Calcium Alginate, Sodium

18. Calginat

19. Copper Alginate

20. Kalrostat

21. Kalrostat 2

22. Kaltostat

23. Poly(mannuronic Acid), Sodium Salt

24. Potassium Alginate

25. Sodium Alginate

26. Sodium Calcium Alginate

27. Vocoloid

28. Xantalgin

2.2.2 Depositor-Supplied Synonyms

1. 9005-34-9

2. 6-(2-carboxy-4,5-dihydroxy-6-methoxyoxan-3-yl)oxy-4,5-dihydroxy-3-methoxyoxane-2-carboxylic Acid

3. Kaltostat

4. 3-((6-carboxy-3,4-dihydroxy-5-methoxytetrahydro-2h-pyran-2-yl)oxy)-4,5-dihydroxy-6-methoxytetrahydro-2h-pyran-2-carboxylic Acid

5. Schembl10118904

6. Akos015915207

7. A843434

8. 6-(2-carboxy-4,5-dihydroxy-6-methoxy-tetrahydropyran-3-yl)oxy-4,5-dihydroxy-3-methoxy-tetrahydropyran-2-carboxylic Acid

2.3 Create Date

2006-06-06

3 Chemical and Physical Properties

Molecular Formula	C₁₄H₂₂O₁₃
Molecular Weight	398.32 g/mol
XLogP3	-3.7
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	13
Rotatable Bond Count	6
Exact Mass	398.10604075 g/mol
Monoisotopic Mass	398.10604075 g/mol
Topological Polar Surface Area	202 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	541
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	10
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Minimum/Potential Fatal Human Dose

1(?). 1= PRACTICALLY NONTOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) ABOVE 15 G/KG, MORE THAN 1 QUART (2.2 LB) FOR 70 KG PERSON (150 LB). /ALGINIC ACID/

Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. II-155

5 Pharmacology and Biochemistry

5.1 Absorption, Distribution and Excretion

ALGINATE PREPARED FROM LAMINARIA DIGITATA WAS UNABSORBED BY RATS FED AT LEVEL OF 10% OF THEIR DAILY DIET. /ALGINATE/

The Chemical Society. Foreign Compound Metabolism in Mammals Volume 3. London: The Chemical Society, 1975., p. 344

FDF Dossiers