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Chemistry

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Also known as: 1867-66-9, Vetalar, Ketaset, Ketalar, Ketamine hcl, Ketanest
Molecular Formula
C13H17Cl2NO
Molecular Weight
274.18  g/mol
InChI Key
VCMGMSHEPQENPE-UHFFFAOYSA-N
FDA UNII
O18YUO0I83

Ketamine Hydrochloride
A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
1 2D Structure

Ketamine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one;hydrochloride
2.1.2 InChI
InChI=1S/C13H16ClNO.ClH/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14;/h2-3,6-7,15H,4-5,8-9H2,1H3;1H
2.1.3 InChI Key
VCMGMSHEPQENPE-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CNC1(CCCCC1=O)C2=CC=CC=C2Cl.Cl
2.2 Other Identifiers
2.2.1 UNII
O18YUO0I83
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(2-chlorophenyl)-2-(methylamino)cyclohexanone

2. Calipsol

3. Calypsol

4. Ci 581

5. Ci-581

6. Ci581

7. Kalipsol

8. Ketalar

9. Ketamine

10. Ketanest

11. Ketaset

2.3.2 Depositor-Supplied Synonyms

1. 1867-66-9

2. Vetalar

3. Ketaset

4. Ketalar

5. Ketamine Hcl

6. Ketanest

7. Ketolar

8. 2-(2-chlorophenyl)-2-(methylamino)cyclohexanone Hydrochloride

9. Cl 369

10. Cn-52,372-2

11. (+-)-ketamine Hydrochloride

12. Ci-581

13. Ketamine Hydrochloride Ciii

14. Ketamine (as Hydrochloride)

15. O18yuo0i83

16. Calipsol

17. Kalipsol

18. Ketavet

19. (+-)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone Hydrochloride

20. Cl-369

21. Dea No. 7285

22. Cn-523722

23. 2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one;hydrochloride

24. Cn-52372-2

25. Ketamine Chloride

26. Ketavet 100

27. Ketavet (veterinary)

28. Ci 581

29. Chebi:650657

30. Einecs 217-484-6

31. Unii-o18yuo0i83

32. Ketalar (tn)

33. Ketamini Hydrochloridum

34. Ketamine Hydrochloride [usan:usp:jan]

35. Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, Hydrochloride

36. Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, Hydrochloride, (+-)-

37. Ec 217-484-6

38. Chembl1714

39. Schembl26999

40. Dtxsid4040137

41. Ketamine Hydrochloride [mi]

42. 2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one Hydrochloride

43. Bcp25943

44. Ketamine Hydrochloride (jp17/usp)

45. Ketamine Hydrochloride [jan]

46. (+/-)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone Hydrochloride

47. Ketamine Hydrochloride [usan]

48. Nsc116131

49. (+/-)-ketamine Hydrochloride, Solid

50. Ketamine Hydrochloride [vandf]

51. Akos005287313

52. Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, Hydrochloride, (+-)-

53. Ketamine Hydrochloride [mart.]

54. Ab02117

55. Ketamine Hydrochloride [who-dd]

56. Ketamine Hydrochloride [who-ip]

57. Nsc-116131

58. Ketamine Hydrochloride [green Book]

59. Db-044614

60. Db-048467

61. Ketamine Hydrochloride [ep Impurity]

62. Ketamine Hydrochloride [orange Book]

63. Ketamine Hydrochloride [ep Monograph]

64. Ketamine Hydrochloride Ciii [usp-rs]

65. Ketamine Hydrochloride [usp Monograph]

66. Ketamini Hydrochloridum [who-ip Latin]

67. C07843

68. D00711

69. 867k669

70. A813079

71. Q-201266

72. Q27105184

73. Ketamine Hydrochloride 1.0 Mg/ml In Methanol (as Free Base)

74. 2-(2-chlorophenyl)-2-(methylamino)-1-cyclohexanone Hydrochloride

75. Ketamine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

76. Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, Hydrochloride (1:1)

77. Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, Hydrochloride, (+/-)-

78. Ketamine (+-)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanonehydrochloride

79. Ketamine Hydrochloride Solution, 1.0 Mg/ml In Methanol (as Free Base), Ampule Of 1 Ml, Certified Reference Material

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 274.18 g/mol
Molecular Formula C13H17Cl2NO
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass273.0687196 g/mol
Monoisotopic Mass273.0687196 g/mol
Topological Polar Surface Area29.1 Ų
Heavy Atom Count17
Formal Charge0
Complexity269
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NameKetalar
Drug LabelKetalar is a nonbarbiturate anesthetic chemically designated dl 2-(0-chlorophenyl)-2-(methylamino) cyclohexanone hydrochloride. It is formulated as a slightly acid (pH 3.5-5.5) sterile solution for intravenous or intramuscular injection in concentrat...
Active IngredientKetamine hydrochloride
Dosage FormInjectable
RouteInjection
Strengtheq 10mg base/ml; eq 50mg base/ml; eq 100mg base/ml
Market StatusPrescription
CompanyPar Sterile Products

2 of 4  
Drug NameKetamine hydrochloride
PubMed HealthKetamine (Injection)
Drug LabelKetamine hydrochloride is a nonbarbiturate anesthetic chemically designated dl 2-(0-chlorophenyl)-2-(methylamino) cyclohexanone hydrochloride. It is formulated as a slightly acid (pH 3.5-5.5) sterile solution for intravenous or intramuscular injectio...
Active IngredientKetamine hydrochloride
Dosage FormInjectable
RouteInjection
Strengtheq 10mg base/ml; eq 50mg base/ml; eq 100mg base/ml
Market StatusPrescription
CompanyHospira; Mylan Institutional; Eurohlth Intl

3 of 4  
Drug NameKetalar
Drug LabelKetalar is a nonbarbiturate anesthetic chemically designated dl 2-(0-chlorophenyl)-2-(methylamino) cyclohexanone hydrochloride. It is formulated as a slightly acid (pH 3.5-5.5) sterile solution for intravenous or intramuscular injection in concentrat...
Active IngredientKetamine hydrochloride
Dosage FormInjectable
RouteInjection
Strengtheq 10mg base/ml; eq 50mg base/ml; eq 100mg base/ml
Market StatusPrescription
CompanyPar Sterile Products

4 of 4  
Drug NameKetamine hydrochloride
PubMed HealthKetamine (Injection)
Drug LabelKetamine hydrochloride is a nonbarbiturate anesthetic chemically designated dl 2-(0-chlorophenyl)-2-(methylamino) cyclohexanone hydrochloride. It is formulated as a slightly acid (pH 3.5-5.5) sterile solution for intravenous or intramuscular injectio...
Active IngredientKetamine hydrochloride
Dosage FormInjectable
RouteInjection
Strengtheq 10mg base/ml; eq 50mg base/ml; eq 100mg base/ml
Market StatusPrescription
CompanyHospira; Mylan Institutional; Eurohlth Intl

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anesthetics, Dissociative

Intravenous anesthetics that induce a state of sedation, immobility, amnesia, and marked analgesia. Subjects may experience a strong feeling of dissociation from the environment. The condition produced is similar to NEUROLEPTANALGESIA, but is brought about by the administration of a single drug. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) (See all compounds classified as Anesthetics, Dissociative.)


Analgesics

Compounds capable of relieving pain without the loss of CONSCIOUSNESS. (See all compounds classified as Analgesics.)


Excitatory Amino Acid Antagonists

Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. (See all compounds classified as Excitatory Amino Acid Antagonists.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
General Anesthetic [EPC]; General Anesthesia [PE]

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Seqens

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Arevipharma Gmbh

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Certificate Number : CEP 2005-281 - Rev 02

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Certificate Number : CEP 2016-194 - Rev 01

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KETAMINE HYDROCHLORIDE

Registration Number : 218MF10980

Registrant's Address : Raiffeisenstrasse 4, D-77933 Lahr Germany

Initial Date of Registration : 2006-12-01

Latest Date of Registration : 2021-12-09

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Ketamine Hydrochloride (BP/EP/USP)

Date of Issue : 2022-06-29

Valid Till : 2025-07-02

Written Confirmation Number : WC-0218

Address of the Firm : A-5/2, Late Parshuram Industrial Area, MIDC, Tal-Khed, Dist. Ratnagiri-415 722, ...

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KETAMINE HYDROCHLORIDE

NDC Package Code : 54382-128

Start Marketing Date : 1989-08-02

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT FOR HUMAN P...

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KETAMINE HYDROCHLORIDE

NDC Package Code : 54382-114

Start Marketing Date : 1989-02-08

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Marketing Category : BULK INGREDIENT

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PCAS

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KETAMINE HYDROCHLORIDE

NDC Package Code : 49169-1041

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KETAMINE HYDROCHLORIDE

NDC Package Code : 61281-8000

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KETAMINE HYDROCHLORIDE, (R)-

NDC Package Code : 10920-701

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KETAMINE HYDROCHLORIDE

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Fagron Services BV

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KETAMINE HYDROCHLORIDE

NDC Package Code : 76003-2673

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KETAMINE HYDROCHLORIDE

NDC Package Code : 62991-1087

Start Marketing Date : 2009-06-11

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Medisca Inc.

U.S.A
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KETAMINE HYDROCHLORIDE

NDC Package Code : 38779-1754

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KETAMINE HYDROCHLORIDE

NDC Package Code : 51927-0292

Start Marketing Date : 2002-07-19

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

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Seqens

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Ketamine Hydrochloride

About the Company : Since its inception in 2003, Seqens has grown to become a global leader in pharmaceutical solutions and specialty ingredients. Seqens supports its customers in developing, scaling ...

Since its inception in 2003, Seqens has grown to become a global leader in pharmaceutical solutions and specialty ingredients. Seqens supports its customers in developing, scaling up and manufacturing drug substances from the pre-clinical phase to the commercial phase. It offers a large portfolio of APIs and proprietary products. Seqens also develops custom solutions and ingredients for the most demanding industries, such as healthcare, electronics and cosmetics. Its unique range of technologies enables it to manufacture complex molecules for small- and large-scale demands. It operates 24 industrial plants and 10 R&D centres across the globe.
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02

LGM Pharma

U.S.A
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Antibody Engineering
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothLGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

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Ketamine

About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.
LGM Pharma CB

03

Suanfarma

Spain
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSuanfarma, at the Core of a Better Life.

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Ketamine Hydrochloride

About the Company : Suanfarma founded in 1993, is a B2B life science partner committed to health & innovation by developing, manufacturing, & distributing high-quality APIs for the pharmaceutical indu...

Suanfarma founded in 1993, is a B2B life science partner committed to health & innovation by developing, manufacturing, & distributing high-quality APIs for the pharmaceutical industry innovatively & sustainably. Backed by a robust global network of 12 strategically located local offices, we cater to the needs of over 400 active customers in 70+ countries. At Suanfarma we offer our CDMO capacity for fermentation & chemical synthesis projects, offering a One Stop Shop service with a solid track record, & which allows us to achieve success in the development, scaling, manufacturing, & commercialization of an API, either innovative or generic.
Suanfarma

04

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Antibody Engineering
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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Ketamine Hydrochloride

About the Company : Supriya Lifescience Ltd. specializes in API manufacturing, focusing on therapeutic segments like antihistamines, anti-allergic drugs, vitamins, anaesthetics and anti-asthmatics. Su...

Supriya Lifescience Ltd. specializes in API manufacturing, focusing on therapeutic segments like antihistamines, anti-allergic drugs, vitamins, anaesthetics and anti-asthmatics. Supriya follows industry standards and constantly improves to deliver quality products. Its facility is 47,000 square meters with dedicated areas for warehouse, QA, QC, R&D, production and finished products. The current capacity is 550 KL, with plans to expand to over 1000 KL by 2024. Supriya has 14 active USDMFs, 8 active CEPs, strong R&D and compliant facilities worldwide. Supriya works with innovators, generic companies, and as a CMO.
Supriya

05

Arevipharma

Germany
Antibody Engineering
Not Confirmed
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Arevipharma

Germany
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Antibody Engineering
Not Confirmed

Ketamine Hydrochloride

About the Company : Arevipharma GmbH is a modern manufacturer of active pharmaceutical ingredients and intermediates with more than 140 years of expertise. Our customers are generic and research-based...

Arevipharma GmbH is a modern manufacturer of active pharmaceutical ingredients and intermediates with more than 140 years of expertise. Our customers are generic and research-based pharmaceutical companies on five continents. Our business partners recognise us as a competent, reliable and efficient company that is distinguished by individual service and an innovative character. The company’s 140 year history is based on the knowledge, skills, commitment and loyalty of its employees. Arevipharma also feels committed to its owners and investors. Due to the consistent expansion of new technologies,
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06

Arevipharma

Germany
Antibody Engineering
Not Confirmed
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Arevipharma

Germany
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Antibody Engineering
Not Confirmed

Ketamine Hydrochloride

About the Company : Arevipharma GmbH is a modern manufacturer of active pharmaceutical ingredients and intermediates with more than 140 years of expertise. Our customers are generic and research-based...

Arevipharma GmbH is a modern manufacturer of active pharmaceutical ingredients and intermediates with more than 140 years of expertise. Our customers are generic and research-based pharmaceutical companies on five continents. Our business partners recognise us as a competent, reliable and efficient company that is distinguished by individual service and an innovative character. The company’s 140 year history is based on the knowledge, skills, commitment and loyalty of its employees. Arevipharma also feels committed to its owners and investors. Due to the consistent expansion of new technologies,
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07

Biotechnica DWC

Algeria
Antibody Engineering
Not Confirmed
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Biotechnica DWC

Algeria
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Antibody Engineering
Not Confirmed

Ketamine Hydrochloride

About the Company : BIOTECHNICA DWC LLC has carved a niche for itself in providing value added compliance, regulatory qualification, project management and GDP guidance services to pharma companies al...

BIOTECHNICA DWC LLC has carved a niche for itself in providing value added compliance, regulatory qualification, project management and GDP guidance services to pharma companies all over the world. Biotechnica is an integrated global solution provider from design to implementation of industrial projects in the areas of Pharmaceuticals,Agri-food ,Cosmetics and Nutrition. With more than 25 years of experience in the assembly of plants, particularly in the pharmaceutical sector, we accompany our customers in the various stages of their projects – E-CTD Dossieers – Raw Materiels – Equipements – Accessories – Packaging – Distribution.
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08

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

Ketamine Hydrochloride

About the Company : Maithri Drugs is one of India's fast-growing pharmaceutical companies. Maithri's strategic focus is on active pharma ingredients (APIs). The company is widely recognized for its ex...

Maithri Drugs is one of India's fast-growing pharmaceutical companies. Maithri's strategic focus is on active pharma ingredients (APIs). The company is widely recognized for its excellent research & development and aggressive growth strategies. Our 32 US DMFs and 9 CEPs in a short span attest to our R&D excellence. Maithri's manufacturing facility is located in Hyderabad. This facility is audited and approved by the US FDA. In addition, our facility is certified according to the standards of DCGI, WHO GMP, and ISO 9001:2015 We have a portfolio of 65 products and are continually expanding.
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09

SB Pharma

Germany
Antibody Engineering
Not Confirmed
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SB Pharma

Germany
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Antibody Engineering
Not Confirmed

Ketamine HCl

About the Company : SB Pharma GmbH, with its headquarters in Cologne, is a leading company that has set itself the goal of offering pharmaceuticals, medical products and medical devices as well as a b...

SB Pharma GmbH, with its headquarters in Cologne, is a leading company that has set itself the goal of offering pharmaceuticals, medical products and medical devices as well as a broad portfolio of other products in the healthcare sector. We are concerned with the constant supply of hospitals and the population with tried-and-tested and innovative medicines. In this way we support a long-term improvement in the quality of life in a wide variety of countries.
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10

UQUIFA

Spain
Antibody Engineering
Not Confirmed
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UQUIFA

Spain
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Antibody Engineering
Not Confirmed

Ketamine Hydrochloride

About the Company : With over 85 years of experience, Uquifa provides comprehensive services supporting projects from proof of concept to commercial manufacturing. Uquifa’s business model is built o...

With over 85 years of experience, Uquifa provides comprehensive services supporting projects from proof of concept to commercial manufacturing. Uquifa’s business model is built on a quality manufacturing platform and a strong track record of service and reliability. Uquifa Group manufactures Active Pharmaceutical Ingredients (APIs) and intermediates for the global pharmaceutical and animal health industries.
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ROAD, G OREGAON WEST,, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1675189800,"product":"KETAMINE HYDROCHLORIDE BP\/EP [EXPORT PMT","address":"11\/12, UDYOG NAGAR,,S.V. ROAD, G OREGAON WEST,","city":"MUMBAI,MAHARASHTRA","supplier":"THEMIS MEDICARE","supplierCountry":"INDIA","foreign_port":"HAMBURG - FUHLSBUETT","customer":"TO THE ORDER OF","customerCountry":"GERMANY","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"280","totalValueFC":"1344","currency":"USD","unitRateINR":22200,"date":"01-Feb-2023","totalValueINR":"111000","totalValueInUsd":"1344","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"7439076","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"11\/12, UDYOG NAGAR,,S.V. ROAD, G OREGAON WEST,, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1675189800,"product":"KETAMINE HYDROCHLORIDE EP [EXPORT PERMIT","address":"11\/12, UDYOG NAGAR,,S.V. ROAD, G OREGAON WEST,","city":"MUMBAI,MAHARASHTRA","supplier":"THEMIS MEDICARE","supplierCountry":"INDIA","foreign_port":"HAMBURG - FUHLSBUETT","customer":"TO THE ORDER OF","customerCountry":"GERMANY","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"280","totalValueFC":"1368.2","currency":"USD","unitRateINR":22600,"date":"01-Feb-2023","totalValueINR":"113000","totalValueInUsd":"1368.2","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"7433635","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"11\/12, UDYOG NAGAR,,S.V. ROAD, G OREGAON WEST,, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1688149800,"product":"KETAMINE HYDROCHLORIDE BP [EXPORT PERMIT","address":"11\/12, UDYOG NAGAR,,S.V. ROAD, G OREGAON WEST,","city":"MUMBAI,MAHARASHTRA","supplier":"THEMIS MEDICARE","supplierCountry":"INDIA","foreign_port":"HAMBURG - FUHLSBUETT","customer":"TO THE ORDER OF","customerCountry":"GERMANY","quantity":"2500.00","actualQuantity":"2500","unit":"KGS","unitRateFc":"280","totalValueFC":"681412.8","currency":"USD","unitRateINR":22401.999875999998,"date":"01-Jul-2023","totalValueINR":"56004999.69","totalValueInUsd":"681412.8","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"11\/12, UDYOG NAGAR,,S.V. ROAD, G OREGAON WEST,, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1696012200,"product":"KETAMINE HYDROCHLORIDE BP [EXPORT PERMIT.NO.P-EXP-14526\/2023 DT.27.09.2023,IMPORT PERMIT.NO.U 00428\/2022 DT. 19.12.2022]","address":"11\/12, UDYOG NAGAR,","city":"MUMBAI, MAHARASHTRA.","supplier":"THEMIS MEDICARE","supplierCountry":"INDIA","foreign_port":"HAMBURG - FUHLSBUETT","customer":"TO THE ORDER OF","customerCountry":"GERMANY","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"270","totalValueFC":"565160.9","currency":"EUR","unitRateINR":23456.5,"date":"30-Sep-2023","totalValueINR":"46913000","totalValueInUsd":"565160.9","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"4323588","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"11\/12, UDYOG NAGAR,, MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1696012200,"product":"KETAMINE HYDROCHLORIDE BP [EXPORT PERMIT.NO.P-EXP-14527\/2023 DT.27.09.2023,IMPORT PERMIT.NO.U 00428\/2022 DT. 19.12.2022]","address":"11\/12, UDYOG NAGAR,","city":"MUMBAI, MAHARASHTRA.","supplier":"THEMIS MEDICARE","supplierCountry":"INDIA","foreign_port":"HAMBURG - FUHLSBUETT","customer":"TO THE ORDER OF","customerCountry":"GERMANY","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"270","totalValueFC":"565160.9","currency":"EUR","unitRateINR":23456.5,"date":"30-Sep-2023","totalValueINR":"46913000","totalValueInUsd":"565160.9","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"4323585","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"11\/12, UDYOG NAGAR,, MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713724200,"product":"PHARMACEUTICAL RAW MATERIAL [ KETAMINE HYDROCHLORIDE USP]BATCH NO. KH01\/030224][MANFG.DT:MAR2024][EXP.\/RETEST DT:MAR2027","address":"216, M.G.ROAD,","city":"KOLKATA (W.B.)","supplier":"BNM ORGANICS","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"TO THE ORDER OF:","customerCountry":"BANGLADESH","quantity":"70.00","actualQuantity":"70","unit":"KGS","unitRateFc":"395","totalValueFC":"27256.9","currency":"USD","unitRateINR":32516.458571428571,"date":"22-Apr-2024","totalValueINR":"2276152.1","totalValueInUsd":"27256.9","indian_port":"Calcutta Air","hs_no":"29223900","bill_no":"9298344","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"Calcutta Air","supplierAddress":"216, M.G.ROAD,, KOLKATA (W.B.)","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1689273000,"product":"KETAMINE HYDROCHLORIDE (USP, PH. EUR.)","address":"No. 9\/215, Pudupakkam - Vandalur Main Road Pudupakkam","city":"Kelambakkam","supplier":"SEQENS","supplierCountry":"GERMANY","foreign_port":"NA","customer":"PAR PHARMACEUTICAL","customerCountry":"INDIA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"2350","totalValueFC":"7141","currency":"USD","unitRateINR":"195637.5","date":"14-Jul-2023","totalValueINR":"586912.641","totalValueInUsd":"7141","indian_port":"BOMBAY AIR","hs_no":"29223900","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"No. 9\/215, Pudupakkam - Vandalur Main Road Pudupakkam"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1721241000,"product":"KETAMINE HYDROCHLORIDE BATCH NO-24M30096","address":"882\/1-871, NEAR KANKAVATI ,VILLAGE-","city":"AHMEDABAD, GUJARAT","supplier":"AREVIPHARMA","supplierCountry":"GERMANY","foreign_port":"BERLIN","customer":"AMNEAL PHARMACEUTICALS","customerCountry":"INDIA","quantity":"1.50","actualQuantity":"1.5","unit":"KGS","unitRateFc":"650","totalValueFC":"985","currency":"USD","unitRateINR":"54892.5","date":"18-Jul-2024","totalValueINR":"82338.75","totalValueInUsd":"985","indian_port":"Ahmedabad Air","hs_no":"29223900","bill_no":"4562019","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"BERLIN","supplierAddress":"MEISSNER STR 35 D 01445 RADEBEUL GERMANYSDNF GERMANY","customerAddress":"882\/1-871, NEAR KANKAVATI ,VILLAGE-"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1727721000,"product":"KETAMINE HYDROCHLORIDE USP, PH. EUR.","address":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM","city":"N\/A","supplier":"SEQENS","supplierCountry":"GERMANY","foreign_port":"FRANKFURT AM MAIN, HE","customer":"PAR PHARMACEUTICAL","customerCountry":"INDIA","quantity":"82.00","actualQuantity":"82","unit":"KGS","unitRateFc":"645","totalValueFC":"53251","currency":"USD","unitRateINR":"54567","date":"01-Oct-2024","totalValueINR":"4474494","totalValueInUsd":"53251","indian_port":"Indore-EPZ\/SEZ","hs_no":"29223900","bill_no":"1007031","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT AM MAIN, HE","supplierAddress":"RAIFFEISENSTRASSE 4 D-77933 LAHR, GERMANY","customerAddress":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM"}]
07-Jul-2021
01-Oct-2024
KGS
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

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(USD/KGS)
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Drugs in Development

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Details:

R-107 (ketamine) is an oral NMDA receptor negative allosteric modulator, small molecule drug candidate, which is being evaluated for the treatment of treatment-resistant depression.


Lead Product(s): Ketamine Hydrochloride

Therapeutic Area: Psychiatry/Psychology Brand Name: R-107

Study Phase: Phase IIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 25, 2024

Douglas CDMO

01

Douglas CDMO

New Zealand
arrow

Lead Product(s) : Ketamine Hydrochloride

Therapeutic Area : Psychiatry/Psychology

Highest Development Status : Phase II

Partner/Sponsor/Collaborator : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

Details : R-107 (ketamine) is an oral NMDA receptor negative allosteric modulator, small molecule drug candidate, which is being evaluated for the treatment of treatment-resistant depression.

Brand Name : R-107

Molecule Type : Small molecule

Upfront Cash : Not Applicable

June 25, 2024

Douglas CDMO

Details:

R-107, an oral extended-release dose of racemic ketamine being developed as add-on or monotherapy for treatment resistant depression (TRD). It has demonstrated a significant antidepressant effect with maintenance of response at 3 months, high compliance dosing.


Lead Product(s): Ketamine Hydrochloride

Therapeutic Area: Psychiatry/Psychology Brand Name: R-107

Study Phase: Phase IIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 26, 2023

Douglas CDMO

02

Douglas CDMO

New Zealand
arrow

Lead Product(s) : Ketamine Hydrochloride

Therapeutic Area : Psychiatry/Psychology

Highest Development Status : Phase II

Partner/Sponsor/Collaborator : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

Details : R-107, an oral extended-release dose of racemic ketamine being developed as add-on or monotherapy for treatment resistant depression (TRD). It has demonstrated a significant antidepressant effect with maintenance of response at 3 months, high compliance ...

Brand Name : R-107

Molecule Type : Small molecule

Upfront Cash : Not Applicable

January 26, 2023

Douglas CDMO

Details:

R-107 (extended-release oral dose of ketamine) act as a blocks the NMDA receptor and it is investigated for the treatment of treatment resistant depression.


Lead Product(s): Ketamine Hydrochloride

Therapeutic Area: Psychiatry/Psychology Brand Name: R-107

Study Phase: Phase IIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 15, 2021

Douglas CDMO

03

Douglas CDMO

New Zealand
arrow

Lead Product(s) : Ketamine Hydrochloride

Therapeutic Area : Psychiatry/Psychology

Highest Development Status : Phase II

Partner/Sponsor/Collaborator : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

Details : R-107 (extended-release oral dose of ketamine) act as a blocks the NMDA receptor and it is investigated for the treatment of treatment resistant depression.

Brand Name : R-107

Molecule Type : Small molecule

Upfront Cash : Not Applicable

June 15, 2021

Douglas CDMO

Details:

Ketarx (ketamine) is a NMDA receptor antagonist, which is being evaluated as a potential treatment for mental health, and neurological disorders like parkinsons.


Lead Product(s): Ketamine Hydrochloride

Therapeutic Area: Neurology Brand Name: Ketarx

Study Phase: Phase II/ Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 26, 2024

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04

PharmaTher

Canada
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Antibody Engineering
Not Confirmed

PharmaTher

Canada
arrow
Antibody Engineering
Not Confirmed

Details : Ketarx (ketamine) is a NMDA receptor antagonist, which is being evaluated as a potential treatment for mental health, and neurological disorders like parkinsons.

Brand Name : Ketarx

Molecule Type : Small molecule

Upfront Cash : Not Applicable

November 26, 2024

blank

Details:

MELT-300, a non-intravenous, non-opioid tablet that blends fixed doses of midazolam and ketamine. This medication is designed for procedural sedation during cataract surgery.


Lead Product(s): Midazolam,Ketamine Hydrochloride

Therapeutic Area: Neurology Brand Name: MELT-300

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 20, 2024

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05

Antibody Engineering
Not Confirmed
Antibody Engineering
Not Confirmed

Details : MELT-300, a non-intravenous, non-opioid tablet that blends fixed doses of midazolam and ketamine. This medication is designed for procedural sedation during cataract surgery.

Brand Name : MELT-300

Molecule Type : Small molecule

Upfront Cash : Not Applicable

November 20, 2024

blank

Details:

Ketarx (ketamine) is a NMDA receptor antagonist, which is being evaluated as a potential treatment for mental health, and neurological disorders like parkinsons.


Lead Product(s): Ketamine Hydrochloride

Therapeutic Area: Neurology Brand Name: Ketarx

Study Phase: Phase II/ Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 19, 2024

blank

06

PharmaTher

Canada
arrow
Antibody Engineering
Not Confirmed

PharmaTher

Canada
arrow
Antibody Engineering
Not Confirmed

Details : Ketarx (ketamine) is a NMDA receptor antagonist, which is being evaluated as a potential treatment for mental health, and neurological disorders like parkinsons.

Brand Name : Ketarx

Molecule Type : Small molecule

Upfront Cash : Not Applicable

November 19, 2024

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Details:

SP-26 is a ketamine HCl-based injectable dissolvable polymer implant beng investigated for the treatment of chronic pain and fibromyalgia.


Lead Product(s): Ketamine Hydrochloride

Therapeutic Area: Musculoskeletal Brand Name: SP-26

Study Phase: PreclinicalProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 31, 2024

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07

Silo Pharma

U.S.A
arrow
Antibody Engineering
Not Confirmed

Silo Pharma

U.S.A
arrow
Antibody Engineering
Not Confirmed

Details : SP-26 is a ketamine HCl-based injectable dissolvable polymer implant beng investigated for the treatment of chronic pain and fibromyalgia.

Brand Name : SP-26

Molecule Type : Small molecule

Upfront Cash : Not Applicable

October 31, 2024

blank

Details:

Ketarx (ketamine) is a NMDA receptor antagonist, which is being evaluated as a potential treatment for mental health, and neurological disorders like parkinsons.


Lead Product(s): Ketamine Hydrochloride

Therapeutic Area: Neurology Brand Name: Ketarx

Study Phase: Phase II/ Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 23, 2024

blank

08

PharmaTher

Canada
arrow
Antibody Engineering
Not Confirmed

PharmaTher

Canada
arrow
Antibody Engineering
Not Confirmed

Details : Ketarx (ketamine) is a NMDA receptor antagonist, which is being evaluated as a potential treatment for mental health, and neurological disorders like parkinsons.

Brand Name : Ketarx

Molecule Type : Small molecule

Upfront Cash : Not Applicable

October 23, 2024

blank

Details:

MELT-300, a non-intravenous, non-opioid tablet that blends fixed doses of midazolam and ketamine. This medication is designed for procedural sedation during cataract surgery.


Lead Product(s): Midazolam,Ketamine Hydrochloride

Therapeutic Area: Neurology Brand Name: MELT-300

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 10, 2024

blank

09

Antibody Engineering
Not Confirmed
Antibody Engineering
Not Confirmed

Details : MELT-300, a non-intravenous, non-opioid tablet that blends fixed doses of midazolam and ketamine. This medication is designed for procedural sedation during cataract surgery.

Brand Name : MELT-300

Molecule Type : Small molecule

Upfront Cash : Not Applicable

October 10, 2024

blank

Details:

Ketamine is a NMDA receptor antagonist, which is being evaluated as a potential treatment for mental health, and neurological disorders like parkinsons.


Lead Product(s): Ketamine Hydrochloride

Therapeutic Area: Neurology Brand Name: Ketamine-Generic

Study Phase: Phase II/ Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 04, 2024

blank

10

PharmaTher

Canada
arrow
Antibody Engineering
Not Confirmed

PharmaTher

Canada
arrow
Antibody Engineering
Not Confirmed

Details : Ketamine is a NMDA receptor antagonist, which is being evaluated as a potential treatment for mental health, and neurological disorders like parkinsons.

Brand Name : Ketamine-Generic

Molecule Type : Small molecule

Upfront Cash : Not Applicable

September 04, 2024

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - INJECTABLE;INJECTION - EQ 100MG BASE...DOSAGE - INJECTABLE;INJECTION - EQ 100MG BASE/ML

USFDA APPLICATION NUMBER - 16812

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DOSAGE - INJECTABLE;INJECTION - EQ 10MG BASE/...DOSAGE - INJECTABLE;INJECTION - EQ 10MG BASE/ML

USFDA APPLICATION NUMBER - 16812

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DOSAGE - INJECTABLE;INJECTION - EQ 50MG BASE/...DOSAGE - INJECTABLE;INJECTION - EQ 50MG BASE/ML

USFDA APPLICATION NUMBER - 16812

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