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Chemistry

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Also known as: 127-08-2, Diuretic salt, Acetic acid, potassium salt, Potassium ethanoate, Potassium;acetate, Fema no. 2920
Molecular Formula
C2H3KO2
Molecular Weight
98.14  g/mol
InChI Key
SCVFZCLFOSHCOH-UHFFFAOYSA-M
FDA UNII
M911911U02

Potassium Acetate
A potassium salt used to replenish ELECTROLYTES, for restoration of WATER-ELECTROLYTE BALANCE, as well as a urinary and systemic alkalizer, which can be administered orally or by intravenous infusion. Formerly, it was used in DIURETICS and EXPECTORANTS.
1 2D Structure

Potassium Acetate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
potassium;acetate
2.1.2 InChI
InChI=1S/C2H4O2.K/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1
2.1.3 InChI Key
SCVFZCLFOSHCOH-UHFFFAOYSA-M
2.1.4 Canonical SMILES
CC(=O)[O-].[K+]
2.2 Other Identifiers
2.2.1 UNII
M911911U02
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Acetate, Potassium

2.3.2 Depositor-Supplied Synonyms

1. 127-08-2

2. Diuretic Salt

3. Acetic Acid, Potassium Salt

4. Potassium Ethanoate

5. Potassium;acetate

6. Fema No. 2920

7. Koac

8. Acetic Acid Potassium Salt

9. Kali Aceticum

10. Potassium Acetates

11. Acok

12. Mfcd00012458

13. Acetic Acid, Potassium Salt (1:1)

14. Ch3co2k

15. E261

16. Ins No.261

17. Potassium Acetate Solution, 5m

18. Chebi:32029

19. Ins-261

20. Ins-261(i)

21. E-261

22. M911911u02

23. Octan Draselny [czech]

24. Potassiumacetate

25. Potassium Acetate [jan]

26. Potassium Acetate (tn)

27. Einecs 204-822-2

28. Potassium Acetate In Plastic Container

29. Kaliumazetat

30. Potassium Acetate [usp:jan]

31. Potasium Acetate

32. Potassium Acetat

33. Potassium-acetate

34. Unii-m911911u02

35. Meco2k

36. Ch3cook

37. Potassium Acetate Solution

38. Dsstox_cid_7043

39. Ec 204-822-2

40. Dsstox_rid_78289

41. Dsstox_gsid_27043

42. Kali Aceticum [hpus]

43. Potassium Acetate (jan/usp)

44. Potassium Acetate [ii]

45. Potassium Acetate [mi]

46. Chembl1201058

47. Dtxsid7027043

48. Potassium Acetate [fhfi]

49. Potassium Acetate [inci]

50. Hy-y0319b

51. Potassium Acetate [vandf]

52. Potassium Acetate [mart.]

53. Potassium Acetate A.c.s. Reagent

54. Potassium Acetate [usp-rs]

55. Potassium Acetate [who-dd]

56. Potassium Acetate, Biochemical Grade

57. Tox21_202740

58. S4843

59. Akos003052760

60. Akos015901668

61. Ccg-266027

62. Cs-w020131

63. Db14498

64. Potassium Acetate [orange Book]

65. Potassium Acetate Acs Grade 1kg

66. Potassium Acetate, 8m Aqueous Solution

67. Potassium Acetate [ep Monograph]

68. Ncgc00260288-01

69. Potassium Acetate [usp Monograph]

70. Bp-21033

71. Cas-127-08-2

72. Ft-0645118

73. P2786

74. 4-chloro-n-furfuryl-5-sulfamoylanthranlic Acid

75. D01154

76. Potassium Acetate, Trace Metals Grade 99.98%

77. Potassium Acetate, 1m Aqueous Solution, Ph 7.5

78. Q409199

79. J-005461

80. Potassium Acetate, 8m Aqueous Solution, Rnase Free

81. Potassium Acetate, 1m Aqueous Solution, Ph 7.5, Rnase Free

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 98.14 g/mol
Molecular Formula C2H3KO2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass97.97701082 g/mol
Monoisotopic Mass97.97701082 g/mol
Topological Polar Surface Area40.1 Ų
Heavy Atom Count5
Formal Charge0
Complexity34.6
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NamePotassium acetate in plastic container
Active IngredientPotassium acetate
Dosage FormInjectable
RouteInjection
Strength2meq/ml
Market StatusPrescription
CompanyHospira

2 of 2  
Drug NamePotassium acetate in plastic container
Active IngredientPotassium acetate
Dosage FormInjectable
RouteInjection
Strength2meq/ml
Market StatusPrescription
CompanyHospira

4.2 Drug Indication

Potassium is used to regulate hypokalemia as a primary condition or secondary to other medical conditions.


5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Pharmacological Classes
Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]; Osmotic Laxative [EPC]; Potassium Compounds [CS]; Potassium Salt [EPC]; Increased Large Intestinal Motility [PE]
5.2 ATC Code

B - Blood and blood forming organs

B05 - Blood substitutes and perfusion solutions

B05X - I.v. solution additives

B05XA - Electrolyte solutions

B05XA17 - Potassium acetate


5.3 Absorption, Distribution and Excretion

Route of Elimination

Mostly urine but also skin and feces.


5.4 Mechanism of Action

Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium is maintained by ion pumps in the cell membrane. The cell membrane potential created by potassium and sodium ions allows the cell generate an action potentiala "spike" of electrical discharge. The ability of cells to produce electrical discharge is critical for body functions such as neurotransmission, muscle contraction, and heart function. Potassium is also an essential mineral needed to regulate water balance, blood pressure and levels of acidity.


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STATES","foreign_port":"NEWARK, NJ","customer":"TEKNIRVANA TRADELINK PRIVATE ","customerCountry":"INDIA","quantity":"250.00","actualQuantity":"250","unit":"KGS","unitRateFc":"29","totalValueFC":"7364.9","currency":"USD","unitRateINR":"2561.9","date":"10-Feb-2025","totalValueINR":"640485.63","totalValueInUsd":"7364.9","indian_port":"Bombay Air","hs_no":"29153999","bill_no":"8263522","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Crystalline","supplierPort":"NEWARK, NJ","supplierAddress":"755 JERSEY AVENUE NEW BRUNSWICK, NJ 08901 3605 Closter\/New Jersey, , U nited States United States","customerAddress":"306, STUDIO COMPLEX, NEAR GOTA CHAR"}]
06-Feb-2021
11-Mar-2025
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ABOUT THIS PAGE

Looking for 127-08-2 / Potassium Acetate API manufacturers, exporters & distributors?

Potassium Acetate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Potassium Acetate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Potassium Acetate manufacturer or Potassium Acetate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Potassium Acetate manufacturer or Potassium Acetate supplier.

PharmaCompass also assists you with knowing the Potassium Acetate API Price utilized in the formulation of products. Potassium Acetate API Price is not always fixed or binding as the Potassium Acetate Price is obtained through a variety of data sources. The Potassium Acetate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Potassium Acetate

Synonyms

127-08-2, Diuretic salt, Acetic acid, potassium salt, Potassium ethanoate, Potassium;acetate, Fema no. 2920

Cas Number

127-08-2

Unique Ingredient Identifier (UNII)

M911911U02

About Potassium Acetate

A potassium salt used to replenish ELECTROLYTES, for restoration of WATER-ELECTROLYTE BALANCE, as well as a urinary and systemic alkalizer, which can be administered orally or by intravenous infusion. Formerly, it was used in DIURETICS and EXPECTORANTS.

KOAc Manufacturers

A KOAc manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of KOAc, including repackagers and relabelers. The FDA regulates KOAc manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. KOAc API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of KOAc manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

KOAc Suppliers

A KOAc supplier is an individual or a company that provides KOAc active pharmaceutical ingredient (API) or KOAc finished formulations upon request. The KOAc suppliers may include KOAc API manufacturers, exporters, distributors and traders.

click here to find a list of KOAc suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

KOAc USDMF

A KOAc DMF (Drug Master File) is a document detailing the whole manufacturing process of KOAc active pharmaceutical ingredient (API) in detail. Different forms of KOAc DMFs exist exist since differing nations have different regulations, such as KOAc USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A KOAc DMF submitted to regulatory agencies in the US is known as a USDMF. KOAc USDMF includes data on KOAc's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The KOAc USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of KOAc suppliers with USDMF on PharmaCompass.

KOAc CEP

A KOAc CEP of the European Pharmacopoeia monograph is often referred to as a KOAc Certificate of Suitability (COS). The purpose of a KOAc CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of KOAc EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of KOAc to their clients by showing that a KOAc CEP has been issued for it. The manufacturer submits a KOAc CEP (COS) as part of the market authorization procedure, and it takes on the role of a KOAc CEP holder for the record. Additionally, the data presented in the KOAc CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the KOAc DMF.

A KOAc CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. KOAc CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of KOAc suppliers with CEP (COS) on PharmaCompass.

KOAc NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing KOAc as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for KOAc API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture KOAc as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain KOAc and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a KOAc NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of KOAc suppliers with NDC on PharmaCompass.

KOAc GMP

KOAc Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of KOAc GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right KOAc GMP manufacturer or KOAc GMP API supplier for your needs.

KOAc CoA

A KOAc CoA (Certificate of Analysis) is a formal document that attests to KOAc's compliance with KOAc specifications and serves as a tool for batch-level quality control.

KOAc CoA mostly includes findings from lab analyses of a specific batch. For each KOAc CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

KOAc may be tested according to a variety of international standards, such as European Pharmacopoeia (KOAc EP), KOAc JP (Japanese Pharmacopeia) and the US Pharmacopoeia (KOAc USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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