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Synopsis

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Chemistry

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Also known as: 125110-14-7, Cefixime hydrate, Cefixime [usan], Cefixime (trihydrate), Ytterbium(iii) ionophore i, Citropen
Molecular Formula
C16H21N5O10S2
Molecular Weight
507.5  g/mol
InChI Key
IPYWNMVPZOAFOQ-NABDTECSSA-N
FDA UNII
97I1C92E55

KS-1200
A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
1 2D Structure

KS-1200

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;trihydrate
2.1.2 InChI
InChI=1S/C16H15N5O7S2.3H2O/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7;;;/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27);3*1H2/b20-9-;;;/t10-,14-;;;/m1.../s1
2.1.3 InChI Key
IPYWNMVPZOAFOQ-NABDTECSSA-N
2.1.4 Canonical SMILES
C=CC1=C(N2C(C(C2=O)NC(=O)C(=NOCC(=O)O)C3=CSC(=N3)N)SC1)C(=O)O.O.O.O
2.1.5 Isomeric SMILES
C=CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OCC(=O)O)/C3=CSC(=N3)N)SC1)C(=O)O.O.O.O
2.2 Other Identifiers
2.2.1 UNII
97I1C92E55
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Cefixime

2. Cefixime Anhydrous

3. Fk 027

4. Fk-027

5. Fk027

6. Fr 17027

7. Fr-17027

8. Fr17027

9. Suprax

2.3.2 Depositor-Supplied Synonyms

1. 125110-14-7

2. Cefixime Hydrate

3. Cefixime [usan]

4. Cefixime (trihydrate)

5. Ytterbium(iii) Ionophore I

6. Citropen

7. 97i1c92e55

8. (6r,7r)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;trihydrate

9. Oraken

10. Fk-027

11. Fr-17027

12. Unii-97i1c92e55

13. Cefixime (usp)

14. Mfcd03788802

15. Oroken (tn)

16. Suprax (tn)

17. (e)-cefixime Trihydrate

18. Cefixime [vandf]

19. (6r,7r)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7(sup 2)-(z)-(o-(carboxymethyl)oxime)trihydrate

20. Ytterbium(iii)ionophore I

21. Cefixime [mart.]

22. Cefixime Hydrate (jp17)

23. Cefixime [usp-rs]

24. Cefixime [orange Book]

25. Cefixime Hydrate [jan]

26. Cefixime [ep Monograph]

27. Cefixime [usp Monograph]

28. Cefixime Trihydrate [mi]

29. Hy-b1381a

30. Cefixime Trihydrate [who-dd]

31. Akos015994710

32. Ccg-208807

33. Ks-1200

34. (6r,7r)-7-(((2z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethyloxyimino)acetyl)amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid Trihydrate

35. Cs-0129491

36. D07640

37. 350c371

38. Q27259597

39. Cefixime Trihydrate, For Microbiology, >=98.0% (hplc)

40. Cefixime, United States Pharmacopeia (usp) Reference Standard

41. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2-amino-4-thiazolyl)((carboxymethoxy)imino)acetyl)amino)-3-ethenyl-8-oxo-, Trihydrate, (6r-(6.alpha.,7.beta.(z)))-

2.4 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 507.5 g/mol
Molecular Formula C16H21N5O10S2
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count15
Rotatable Bond Count8
Exact Mass507.07298423 g/mol
Monoisotopic Mass507.07298423 g/mol
Topological Polar Surface Area241 Ų
Heavy Atom Count33
Formal Charge0
Complexity861
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count4
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


ABOUT THIS PAGE

KS-1200 Manufacturers

A KS-1200 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of KS-1200, including repackagers and relabelers. The FDA regulates KS-1200 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. KS-1200 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

KS-1200 Suppliers

A KS-1200 supplier is an individual or a company that provides KS-1200 active pharmaceutical ingredient (API) or KS-1200 finished formulations upon request. The KS-1200 suppliers may include KS-1200 API manufacturers, exporters, distributors and traders.

KS-1200 GMP

KS-1200 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of KS-1200 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right KS-1200 GMP manufacturer or KS-1200 GMP API supplier for your needs.

KS-1200 CoA

A KS-1200 CoA (Certificate of Analysis) is a formal document that attests to KS-1200's compliance with KS-1200 specifications and serves as a tool for batch-level quality control.

KS-1200 CoA mostly includes findings from lab analyses of a specific batch. For each KS-1200 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

KS-1200 may be tested according to a variety of international standards, such as European Pharmacopoeia (KS-1200 EP), KS-1200 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (KS-1200 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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