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1. 2 Hydroxypropanoic Acid
2. 2 Hydroxypropionic Acid
3. 2-hydroxypropanoic Acid
4. 2-hydroxypropionic Acid
5. Ammonium Lactate
6. D Lactic Acid
7. D-lactic Acid
8. L Lactic Acid
9. Lactate
10. Lactate, Ammonium
11. Lactic Acid
12. Propanoic Acid, 2-hydroxy-, (2r)-
13. Propanoic Acid, 2-hydroxy-, (2s)-
14. Sarcolactic Acid
1. 79-33-4
2. L-(+)-lactic Acid
3. (s)-lactic Acid
4. (s)-2-hydroxypropanoic Acid
5. Sarcolactic Acid
6. (s)-2-hydroxypropionic Acid
7. (2s)-2-hydroxypropanoic Acid
8. (+)-lactic Acid
9. (s)-(+)-lactic Acid
10. Paralactic Acid
11. L(+)-lactic Acid
12. Lactic Acid, L-
13. Espiritin
14. Tisulac
15. Purac
16. (s)-lactate
17. L-lactate
18. Propanoic Acid, 2-hydroxy-, (2s)-
19. Sarcolacticum Acidum
20. L-(+)-alpha-hydroxypropionic Acid
21. Ph 90
22. Propanoic Acid, 2-hydroxy-, (s)-
23. F9s9ffu82n
24. Chebi:422
25. Paramilchsaeure
26. (2s)-2-hydroxypropanoic Acid Homopolymer
27. Fleischmilchsaeure
28. (+)-lactate
29. (s)-milchsaeure
30. Propanoic Acid, 2-hydroxy-, (s)-, Homopolymer
31. Acidum Sarcolacticum
32. Pleo Sanvis
33. Mfcd00064266
34. (s)-2-hydroxypropionsaeure
35. 2-hydroxy-propionic Acid
36. Plla
37. Alpha-hydroxypropanoic Acid
38. Einecs 201-196-2
39. Unii-f9s9ffu82n
40. Brn 1720251
41. 1-hydroxyethane 1-carboxylic Acid
42. L(+)-2-hydroxypropionsaeure
43. L-lacticacid
44. L-milchsaeure
45. (alpha)-lactate
46. L-iactic Acid
47. Lactic Acid Fcc
48. A-hydroxypropanoate
49. A-hydroxypropionate
50. 2op
51. Nchembio867-comp9
52. (alpha)-lactic Acid
53. Alpha-hydroxypropanoate
54. Alpha-hydroxypropionate
55. L-2-hydroxypropanoate
56. A-hydroxypropanoic Acid
57. A-hydroxypropionic Acid
58. L-(+) Lactic Acid
59. L-lactic Acid, 90%
60. (s)-2-hydroxypropanoate
61. (s)-2-hydroxypropionate
62. 1-hydroxyethanecarboxylate
63. L-lactic Acid, Anhydrous
64. L-2-hydroxypropanoic Acid
65. Bmse000208
66. Bmse000818
67. Bmse000979
68. (s)-2-hydroxy-propanoate
69. Ec 201-196-2
70. L-lactic Acid [mi]
71. L-lactic Acid [jan]
72. 4-03-00-00633 (beilstein Handbook Reference)
73. L-(+)-lactic Acid Solution
74. 1-hydroxyethane 1-carboxylate
75. (s)-2-hydroxy-propanoic Acid
76. (s)-2-hydroxy-propionic Acid
77. Chembl330546
78. Gtpl2932
79. L- Lactic Acid (+)
80. (s)-(+)-2-hydroxypropanoate
81. L-(+)-lactic Acid, 80%
82. (s)(+)2 Hydroxypropionic Acid
83. Dtxsid6034689
84. Lactic Acid, L- [ii]
85. Dextrorotatory Lactic Acid
86. (s)(+)-2 Hydroxypropionic Acid
87. L-lactic Acid Solution, 90.0%
88. Sarcolactic Acid [who-dd]
89. L-(+)-lactic Acid 95% Liquid
90. 80% (w/w) Lactic Acid Solution
91. L-(+)-lactic Acid Solution, 1m
92. L-(+)-lactic Acid, >=98%
93. Sarcolacticum Acidum [hpus]
94. (s)-(+)-2-hydroxypropanoic Acid
95. 2-hydroxypropanoic Acid, (s)- #
96. Hy-y0479
97. Zinc4658560
98. S6250
99. Akos025146504
100. Db14475
101. L-lactic Acid, Crystalline, 98.0%+
102. (s)-lactic Acid [ep Monograph]
103. L-(+)-lactic Acid, Analytical Standard
104. Cs-0015266
105. Ft-0773848
106. L0165
107. L-(+)-lactic Acid Solution, ~40% In H2o
108. C00186
109. D71144
110. L-0990
111. L-1000
112. L-(+)-lactic Acid Solution, In H2o, >=85%
113. L-(+)-lactic Acid, Bioxtra, >=98% (titration)
114. L-(+)-lactic Acid, Vetec(tm) Reagent Grade, 86%
115. Q27080955
116. 5e39d33d-2f71-4c24-bc7a-5e6f27e4cf83
117. L-(+)-lactic Acid Solution, 30% In H2o (by Weight)
118. L-(+)-lactic Acid Solution, ~50% (l-lactic Acid In Water)
119. L-(+)-lactic Acid Solution, Purum, ~20% (l-lactic Acid In Water)
120. L+lactic Acid, Free Acid (s)-2-hydroxypropionic Acid, Sarcolactic Acid
121. L-(+)-lactic Acid Solution, Acs Reagent, 85-90% (l-lactic Acid In Water)
122. L-(+)-lactic Acid Solution, Purum P.a., 79-81% (l-lactic Acid In Water, T)
123. L-(+)-lactic Acid Solution, Meets Analytical Specification Of Ph.??eur., Bp, 88-92% Total Acid Basis
| Molecular Weight | 90.08 g/mol |
|---|---|
| Molecular Formula | C3H6O3 |
| XLogP3 | -0.7 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Exact Mass | 90.031694049 g/mol |
| Monoisotopic Mass | 90.031694049 g/mol |
| Topological Polar Surface Area | 57.5 Ų |
| Heavy Atom Count | 6 |
| Formal Charge | 0 |
| Complexity | 59.1 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Prevention of pregnancy
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GDUFA
DMF Review : Reviewed
Rev. Date : 2022-09-28
Pay. Date : 2022-09-23
DMF Number : 20726
Submission : 2007-07-26
Status : Active
Type : II
Certificate Number : R1-CEP 2006-124 - Rev 01
Issue Date : 2023-04-27
Type : Chemical
Substance Number : 1771
Status : Valid
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USDMF
GDUFA
DMF Review : Complete
Rev. Date : 2022-09-28
Pay. Date : 2022-09-23
DMF Number : 20726
Submission : 2007-07-26
Status : Active
Type : II
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]CEP/COS
Certificate Number : R1-CEP 2006-124 - Rev 01
Status : Valid
Issue Date : 2023-04-27
Type : Chemical
Substance Number : 1771
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results] API Reference Price
API Imports and Exports
| Importing Country | Total Quantity (KGS) |
Average Price (USD/KGS) |
Number of Transactions |
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Drugs in Development
Details:
Through the acquisition of Evofem, Aditxt gains access to its first and only FDA-approved hormone-free contraceptive gel, Phexxi (lactic acid, citric acid, and potassium bitartrate).
Lead Product(s): L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: Phexxi
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Aditxt
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Acquisition December 12, 2023
Lead Product(s) : L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Aditxt
Deal Size : Undisclosed
Deal Type : Acquisition
Details : Through the acquisition of Evofem, Aditxt gains access to its first and only FDA-approved hormone-free contraceptive gel, Phexxi (lactic acid, citric acid, and potassium bitartrate).
Brand Name : Phexxi
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 12, 2023
Details:
Sculptra is the first and original injectable collagen stimulator containing microparticles of unique poly-L-lactic acid (PLLA-SCA) which gradually revitalizes the skin’s structural foundation.
Lead Product(s): L-Lactic Acid,Sodium Carboxymethylcellulose
Therapeutic Area: Dermatology Brand Name: Sculptra
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 30, 2023
Lead Product(s) : L-Lactic Acid,Sodium Carboxymethylcellulose
Therapeutic Area : Dermatology
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
AMWC 2023: Data From Sculptra® Cheek Wrinkle and Alluzience® Star Studies Reinforce Strength of ...
Details : Sculptra is the first and original injectable collagen stimulator containing microparticles of unique poly-L-lactic acid (PLLA-SCA) which gradually revitalizes the skin’s structural foundation.
Brand Name : Sculptra
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 30, 2023
Details:
Phexxi® (lactic acid, citric acid and potassium bitartrate) vaginal gel provides women an in-the-moment contraceptive that can be easily applied 0-60 minutes before each act of intercourse and works by maintaining the baseline vaginal pH environment.
Lead Product(s): L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area: Infections and Infectious Diseases Brand Name: Phexxi
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable October 06, 2022
Lead Product(s) : L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Evofem Biosciences Announces Approval of Phexxi in Nigeria
Details : Phexxi® (lactic acid, citric acid and potassium bitartrate) vaginal gel provides women an in-the-moment contraceptive that can be easily applied 0-60 minutes before each act of intercourse and works by maintaining the baseline vaginal pH environment.
Brand Name : Phexxi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 06, 2022
Details:
Phexxi (L-lactic Acid) is a hormone-free, woman-controlled contraceptive gel. It works by maintaining vaginal pH in the optimal range of 3.5 to 4.5, which is inhospitable to sperm, as well as certain bacterial and viral pathogens including chlamydia and gonorrhea.
Lead Product(s): L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: Phexxi
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 23, 2022
Lead Product(s) : L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Evofem Announces Issuance of U.S. Patent Covering Phexxi® Composition of Matter
Details : Phexxi (L-lactic Acid) is a hormone-free, woman-controlled contraceptive gel. It works by maintaining vaginal pH in the optimal range of 3.5 to 4.5, which is inhospitable to sperm, as well as certain bacterial and viral pathogens including chlamydia and ...
Brand Name : Phexxi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 23, 2022
Details:
Phexxi (L-lactic Acid) is an on-demand method of birth control used to prevent pregnancy. Phexxi is not effective when used after sex.
Lead Product(s): L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: Phexxi
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 16, 2022
Lead Product(s) : L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Large Commercial Payer Adds Phexxi® to Formulary for Standard Plans Nationwide
Details : Phexxi (L-lactic Acid) is an on-demand method of birth control used to prevent pregnancy. Phexxi is not effective when used after sex.
Brand Name : Phexxi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 16, 2022
Details:
Phexxi® (lactic acid, citric acid and potassium bitartrate), is a hormone-free, on-demand prescription contraceptive vaginal gel. It comes in a box of 12 pre-filled applicators and is applied 0-60 minutes before each act of sex.
Lead Product(s): L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area: Infections and Infectious Diseases Brand Name: Phexxi
Study Phase: Phase IIIProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable August 01, 2022
Lead Product(s) : L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Phexxi® (lactic acid, citric acid and potassium bitartrate), is a hormone-free, on-demand prescription contraceptive vaginal gel. It comes in a box of 12 pre-filled applicators and is applied 0-60 minutes before each act of sex.
Brand Name : Phexxi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 01, 2022
Details:
Phexxi® (lactic acid, citric acid, and potassium bitartrate), is a hormone-free, on-demand prescription contraceptive vaginal gel, an on-demand method of birth control used to prevent pregnancy.
Lead Product(s): L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: Phexxi
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 12, 2022
Lead Product(s) : L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Phexxi® Mechanism of Action Article Published in the Journal of Therapeutic Advances in Reproduct...
Details : Phexxi® (lactic acid, citric acid, and potassium bitartrate), is a hormone-free, on-demand prescription contraceptive vaginal gel, an on-demand method of birth control used to prevent pregnancy.
Brand Name : Phexxi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 12, 2022
Details:
Phexxi's (L-lactic Acid) mechanism of action through vaginal pH modulation results in the immobilization of spermatozoa by maintaining the normally low vaginal pH, even in the presence of semen.
Lead Product(s): L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: Phexxi
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable June 16, 2022
Lead Product(s) : L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Phexxi® Prevented 99% of Pregnancies Per Act of Intercourse in a Post Hoc Analysis of Phase 3 AMP...
Details : Phexxi's (L-lactic Acid) mechanism of action through vaginal pH modulation results in the immobilization of spermatozoa by maintaining the normally low vaginal pH, even in the presence of semen.
Brand Name : Phexxi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 16, 2022
Details:
Evofem intends to use the proceeds from the offering for the continuation of commercialization activities related to its commercial product, Phexxi® (lactic acid, citric acid, and potassium bitartrate) vaginal gel, the continuation of its registrational Phase 3 clinical trial.
Lead Product(s): L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: Phexxi
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Piper Sandler & Co.
Deal Size: $26.6 million Upfront Cash: Undisclosed
Deal Type: Public Offering May 20, 2022
Lead Product(s) : L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Piper Sandler & Co.
Deal Size : $26.6 million
Deal Type : Public Offering
Evofem Biosciences Announces Pricing of Approximately $26.6 Million Public Offering
Details : Evofem intends to use the proceeds from the offering for the continuation of commercialization activities related to its commercial product, Phexxi® (lactic acid, citric acid, and potassium bitartrate) vaginal gel, the continuation of its registrational...
Brand Name : Phexxi
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 20, 2022
Details:
Evofem intends to use the net proceeds from the offering for the continuation of commercialization activities related to its commercial product, Phexxi® (lactic acid, citric acid, and potassium bitartrate) vaginal gel.
Lead Product(s): L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: Phexxi
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Piper Sandler & Co
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Public Offering May 19, 2022
Lead Product(s) : L-Lactic Acid,Citric Acid,Potassium Bitartrate
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Piper Sandler & Co
Deal Size : Undisclosed
Deal Type : Public Offering
Evofem Biosciences Announces Proposed Public Offering
Details : Evofem intends to use the net proceeds from the offering for the continuation of commercialization activities related to its commercial product, Phexxi® (lactic acid, citric acid, and potassium bitartrate) vaginal gel.
Brand Name : Phexxi
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 19, 2022
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