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L-Tartaric Acid

Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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Chemistry

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Also known as: (+)-l-tartaric acid, (+)-tartaric acid, 87-69-4, L-(+)-tartaric acid, L(+)-tartaric acid, Tartaric acid

Molecular Formula

C₄H₆O₆

Molecular Weight

150.09 g/mol

InChI Key

FEWJPZIEWOKRBE-JCYAYHJZSA-N

FDA UNII

W4888I119H

Tartaric Acid is a white crystalline dicarboxylic acid found in many plants, particularly tamarinds and grapes. Tartaric acid is used to generate carbon dioxide through interaction with sodium bicarbonate following oral administration. Carbon dioxide extends the stomach and provides a negative contrast medium during double contrast radiography. In high doses, this agent acts as a muscle toxin by inhibiting the production of malic acid, which could cause paralysis and maybe death.

1 2D Structure

L-Tartaric Acid

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2R,3R)-2,3-dihydroxybutanedioic acid

2.1.2 InChI

InChI=1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)/t1-,2-/m1/s1

2.1.3 InChI Key

FEWJPZIEWOKRBE-JCYAYHJZSA-N

2.1.4 Canonical SMILES

C(C(C(=O)O)O)(C(=O)O)O

2.1.5 Isomeric SMILES

[C@@H]([C@H](C(=O)O)O)(C(=O)O)O

2.2 Other Identifiers

2.2.1 UNII

W4888I119H

2.3 Synonyms

2.3.1 MeSH Synonyms

1. (r*,r*)-(+-)-2,3-dihydroxybutanedioic Acid, Monoammonium Monosodium Salt

2. Aluminum Tartrate

3. Ammonium Tartrate

4. Calcium Tartrate

5. Calcium Tartrate Tetrahydrate

6. Mn(iii) Tartrate

7. Potassium Tartrate

8. Seignette Salt

9. Sodium Ammonium Tartrate

10. Sodium Potassium Tartrate

11. Sodium Tartrate

12. Stannous Tartrate

13. Tartaric Acid

14. Tartaric Acid, ((r*,r*)-(+-))-isomer

15. Tartaric Acid, (r*,s*)-isomer

16. Tartaric Acid, (r-(r*,r*))-isomer

17. Tartaric Acid, (s-(r*,r*))-isomer

18. Tartaric Acid, Ammonium Sodium Salt, (1:1:1) Salt, (r*,r*)-(+-)-isomer

19. Tartaric Acid, Calcium Salt, (r-r*,r*)-isomer

20. Tartaric Acid, Monoammonium Salt, (r-(r*,r*))-isomer

21. Tartrate

2.3.2 Depositor-Supplied Synonyms

1. (+)-l-tartaric Acid

2. (+)-tartaric Acid

3. 87-69-4

4. L-(+)-tartaric Acid

5. L(+)-tartaric Acid

6. Tartaric Acid

7. (2r,3r)-2,3-dihydroxysuccinic Acid

8. (2r,3r)-2,3-dihydroxybutanedioic Acid

9. (r,r)-tartaric Acid

10. Threaric Acid

11. L-threaric Acid

12. Dextrotartaric Acid

13. Dl-tartaric Acid

14. Natural Tartaric Acid

15. (2r,3r)-(+)-tartaric Acid

16. (+)-(r,r)-tartaric Acid

17. Tartaric Acid, L-

18. Rechtsweinsaeure

19. (2r,3r)-tartaric Acid

20. (2r,3r)-rel-2,3-dihydroxysuccinic Acid

21. Tartrate

22. (r,r)-(+)-tartaric Acid

23. Fema No. 3044

24. 133-37-9

25. Lamb Protein (fungal)

26. Butanedioic Acid, 2,3-dihydroxy- (2r,3r)-

27. (r,r)-tartrate

28. Tartaric Acid (van)

29. Kyselina Vinna [czech]

30. Ins No.334

31. Uvic Acid

32. Chebi:15671

33. (+)-(2r,3r)-tartaric Acid

34. Ins-334

35. Tartaric Acid [usan:jan]

36. Weinsaeure

37. Mfcd00064207

38. Nsc-62778

39. L-tartarate

40. 4j4z8788n8

41. W4888i119h

42. 138508-61-9

43. Butanedioic Acid, 2,3-dihydroxy-, (2r,3r)-rel-

44. 1,2-dihydroxyethane-1,2-dicarboxylic Acid

45. Resolvable Tartaric Acid

46. D-alpha,beta-dihydroxysuccinic Acid

47. E 334

48. E-334

49. L-(+)-tartrate

50. 144814-09-5

51. Kyselina 2,3-dihydroxybutandiova [czech]

52. Ai3-06298

53. (1r,2r)-1,2-dihydroxyethane-1,2-dicarboxylic Acid

54. 2, 3-dihydroxybutanedioic Acid

55. Butanedioic Acid, 2,3-dihydroxy- (2r,3r)-, Homopolymer

56. Kyselina Vinna

57. Tartaric Acid D,l

58. Butanedioic Acid, 2,3-dihydroxy- (r-(r*,r*))-

59. Tartarate

60. 132517-61-4

61. (+/-)-tartaric Acid

62. Succinic Acid, 2,3-dihydroxy

63. L(+) Tartaric Acid

64. L-2,3-dihydroxybutanedioic Acid

65. (2rs,3rs)-tartaric Acid

66. Einecs 201-766-0

67. Nsc 62778

68. Weinsteinsaeure

69. Weinsaure

70. Tartaric-acid

71. L-threaric Aci

72. Unii-w4888i119h

73. Kyselina 2,3-dihydroxybutandiova

74. 4ebt

75. Nsc 148314

76. Nsc-148314

77. (r,r)-tartarate

78. (2r,3r)-2,3-dihydroxybernsteinsaeure

79. (+)-tartarate

80. (+)-weinsaeure

81. L(+)tartaric Acid

82. Tartaric Acid; L-(+)-tartaric Acid

83. Tartaric Acid (tn)

84. (+-)-tartaric Acid

85. Butanedioic Acid, 2,3-dihydroxy-, (r*,r*)-

86. L-(+) Tartaric Acid

87. (2r,3r)-tartarate

88. 1d5r

89. Dl Tartaric Acid

90. Tartaricum Acidum

91. 2,3-dihydroxy-succinate

92. Tartaric Acid,dl-

93. Dsstox_cid_3632

94. Ec 201-766-0

95. Schembl5762

96. Tartaric Acid [ii]

97. Tartaric Acid, Dl-

98. Dsstox_rid_77120

99. Tartaric Acid (jp17/nf)

100. Tartaric Acid [fcc]

101. Tartaric Acid [jan]

102. D-a,b-dihydroxysuccinic Acid

103. Dsstox_gsid_23632

104. Tartaric Acid [inci]

105. Mls001336057

106. L-tartaric Acid [mi]

107. Tartaric Acid [vandf]

108. Dl-tartaric Acid [mi]

109. Tartaric Acid [mart.]

110. Ccris 8978

111. L-(+)-tartaric Acid, Acs

112. Tartaric Acid [usp-rs]

113. Tartaric Acid [who-dd]

114. Chembl1236315

115. Dtxsid8023632

116. L-(+)-tartaric Acid, Bioxtra

117. Tartaricum Acidum [hpus]

118. Unii-4j4z8788n8

119. (2r,3r)-2,3-tartaric Acid

120. Tartaric Acid (l(+)-)

121. Hms2270g22

122. Pharmakon1600-01300044

123. Tartaric Acid, Dl- [ii]

124. Zinc895301

125. Tartaric Acid, (+/-)-

126. Tartaric Acid,dl- [vandf]

127. Hy-y0293

128. Str02377

129. Tartaric Acid [orange Book]

130. Baros Component Tartaric Acid

131. Einecs 205-105-7

132. Tox21_300155

133. (2r,3r)-2,3-dihydroxysuccinicacid

134. Nsc759609

135. S6233

136. Tartaric Acid [ep Monograph]

137. L-2,3-dihydroxysuccinic Acid

138. Akos016843282

139. L-(+)-tartaric Acid, >=99.5%

140. Cs-w020107

141. Db09459

142. Nsc-759609

143. (2r,3r)-2,3-dihydroxy-succinic Acid

144. Butanedioic Acid, 2,3-dihydroxy-; Butanedioic Acid, 2,3-dihydroxy-, (r-(r*,r*))-

145. Cas-87-69-4

146. L-(+)-tartaric Acid, Ar, >=99%

147. Tartaric Acid Component Of Baros

148. Ncgc00247911-01

149. Ncgc00254043-01

150. Bp-31012

151. Smr000112492

152. Sbi-0207063.p001

153. T0025

154. C00898

155. D00103

156. D70248

157. Dl-tartaric Acid 100 Microg/ml In Acetonitrile

158. L-(+)-tartaric Acid, >=99.7%, Fcc, Fg

159. L-(+)-tartaric Acid, Acs Reagent, >=99.5%

160. L-(+)-tartaric Acid, Bioultra, >=99.5% (t)

161. J-500964

162. J-520420

163. L-(+)-tartaric Acid, Reagentplus(r), >=99.5%

164. L-(+)-tartaric Acid, Saj First Grade, >=99.5%

165. L-(+)-tartaric Acid, Tested According To Ph.eur.

166. Rel-(2r,3r)-2,3-dihydroxybutanedioic Acid

167. Butanedioic Acid, 2,3-dihydroxy-, (r*,r*)-(+-)-

168. L-(+)-tartaric Acid, Jis Special Grade, >=99.5%

169. L-(+)-tartaric Acid, Natural, >=99.7%, Fcc, Fg

170. L-(+)-tartaric Acid, P.a., Acs Reagent, 99.0%

171. L-(+)-tartaric Acid, Vetec(tm) Reagent Grade, 99%

172. Q18226455

173. F8880-9012

174. Z1262250859

175. Butanedioic Acid, 2,3-dihydroxy-, (r-(r*,r*))-

176. Butanedioic Acid, 2,3-dihydroxy-, (theta,theta)-(+-)-

177. 000189e3-11d0-4b0a-8c7b-31e02a48a51f

178. L-(+)-tartaric Acid, Puriss. P.a., Acs Reagent, >=99.5%

179. L-(+)-tartaric Acid, Certified Reference Material, Tracecert(r)

180. Tartaric Acid, United States Pharmacopeia (usp) Reference Standard

181. L-(+)-tartaric Acid, Anhydrous, Free-flowing, Redi-dri(tm), Acs Reagent, >=99.5%

182. L-(+)-tartaric Acid, P.a., Acs Reagent, Reag. Iso, Reag. Ph. Eur., 99.5%

183. Tartaric Acid, Pharmaceutical Secondary Standard; Certified Reference Material

184. L-(+)-tartaric Acid, Puriss. P.a., Reag. Iso, Reag. Ph. Eur., 99.5-101.0% (calc. To The Dried Substance)

185. L-(+)-tartaric Acid, Puriss., Meets Analytical Specification Of Ph. Eur., Bp, Nf, Fcc, E334, 99.7-100.5% (calc. To The Dried Substance), Grit

186. L-(+)-tartaric Acid, Puriss., Meets Analytical Specification Of Ph. Eur., Nf, 99.7-100.5% (calc. To The Dried Substance), Powder

2.4 Create Date

2004-09-16

3 Chemical and Physical Properties

Molecular Formula	C₄H₆O₆
Molecular Weight	150.09 g/mol
XLogP3	-1.9
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	150.01643791 g/mol
Monoisotopic Mass	150.01643791 g/mol
Topological Polar Surface Area	115 Å²
Heavy Atom Count	10
Formal Charge	0
Complexity	134
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Indication

Tartaric Acid is primarily indicated in conditions like Antiscorbutic, Antiseptic.

Stress incontinence, female

5 Pharmacology and Biochemistry

5.1 Pharmacology

Tartaric acid is used to generate carbon dioxide through interaction with sodium bicarbonate following oral administration. Carbon dioxide extends the stomach and provides a negative contrast medium during double contrast radiography. In high doses, this agent acts as a muscle toxin by inhibiting the production of malic acid, which could cause paralysis and maybe death.

5.2 Absorption, Distribution and Excretion

Absorption

Oral or parenteral doses of monosodium 14C-L(+)-tartrate (400 mg/kg) are rapidly excreted by rats and a proportion completely metabolized to CO2. The oral dose was well-absorbed.

Route of Elimination

Only about 15-20% of consumed tartaric acid is secreted in the urine unchanged.

5.3 Metabolism/Metabolites

Most tartarate that is consumed by humans is metabolized by bacteria in the gastrointestinal tract , primarily in the large instestine.

API SUPPLIERS

01

Curia

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM

Not Confirmed

02

Jing Jing Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM

Not Confirmed

03

Salvi Chemical Industries

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM

Not Confirmed

04

Quality Chemicals

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM

Not Confirmed

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USDMF

01

Curia New York Inc

U.S.A

Duphat

Not Confirmed

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Listed Suppliers

01

Jing Jing Pharmaceutical

China

Duphat

Not Confirmed

02

Quality Chemicals

Spain

Duphat

Not Confirmed

03

Salvi Chemical Industries

India

Duphat

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

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PHARMACEUTICALS LIMITED","customerCountry":"INDIA","quantity":"570.96","actualQuantity":"570.96","unit":"KGS","unitRateFc":"223","totalValueFC":"128723.4","currency":"USD","unitRateINR":"18943.9","date":"22-Oct-2024","totalValueINR":"10816180.6","totalValueInUsd":"128723.4","indian_port":"Bombay Air","hs_no":"29339990","bill_no":"6275355","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"NO.3 BEIHUAN ROAD,KAIYUAN LIAONING PROVINCE SDNF CN","customerAddress":"ALEMBIC ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729881000,"product":"2-((3AR,4S,6R,6AS)-6-AMINO-2,2-DIMETHYLTETRAHYDRO-3AH-CYCLOPENTA[D][1,3]DIOXOL-4-YLOXY)ETHANOL L-TARTARIC ACID (1:1)","address":"Plot No.157, V V Nagar Colony,","city":"HYDERABAD","supplier":"ZHEJIANG SHINDAI CHEMICALS CO .,LTD","supplierCountry":"CHINA","foreign_port":"JINGDEZHEN","customer":"LEE FINE 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MARKET,","city":"CHANDIGARH.","supplier":"ZHEJIANG RUILIAN PHARMACEAUTICAL CO. 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Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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INTERMEDIATES SUPPLIERS

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FDF Dossiers

01

Acarpia Farmaceutici

Italy

Duphat

Not Confirmed

02

Neopharma

U.A.E

Duphat

Not Confirmed

03

World Medicine

Turkey

Duphat

Not Confirmed

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Europe

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Listed Dossiers

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Related Excipient Companies

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Excipients by Applications

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Coating Systems & Additives

Taste Masking

01

Actylis

U.S.A

Duphat

Not Confirmed

02

Gangwal Chemicals

India

Duphat

Not Confirmed

Thickeners and Stabilizers

Parenteral

Digital Content

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Market Place

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APIs

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INTERMEDIATES

Various Intermediates needed in India [ENA12200]

A company dedicated to the identification, development, production & distribution of potent phytochemicals and botanical extracts is looking for suppliers of Various Intermediates for development purpose. 1. 5-{[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl}-2-imino-4-thiazolidinone (CAS 105355-26-8) Intermediate. The required quantity is 25 kg - 500 kg. 2. 4-aminophenol (CAS 123-30-8) Intermediate. The required quantity is 1 MT. 3. N-Ethyl-N-methyl Carbamoyl Chloride (CAS 42252-34-6) Intermediate. The required quantity is 1 kg. 4. (S)-3-[1-(Dimethyl amino)ethyl]phenol (CAS 139306-10-8) Intermediate. The required quantity is 1 kg. 5. L-tartaric acid (CAS 87-69-4) Intermediate. The required quantity is 1 kg.

23 Dec 2021

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ABOUT THIS PAGE

L-Tartaric Acid Manufacturers

A L-Tartaric Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of L-Tartaric Acid, including repackagers and relabelers. The FDA regulates L-Tartaric Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. L-Tartaric Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of L-Tartaric Acid manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

L-Tartaric Acid Suppliers

A L-Tartaric Acid supplier is an individual or a company that provides L-Tartaric Acid active pharmaceutical ingredient (API) or L-Tartaric Acid finished formulations upon request. The L-Tartaric Acid suppliers may include L-Tartaric Acid API manufacturers, exporters, distributors and traders.

click here to find a list of L-Tartaric Acid suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

L-Tartaric Acid USDMF

A L-Tartaric Acid DMF (Drug Master File) is a document detailing the whole manufacturing process of L-Tartaric Acid active pharmaceutical ingredient (API) in detail. Different forms of L-Tartaric Acid DMFs exist exist since differing nations have different regulations, such as L-Tartaric Acid USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A L-Tartaric Acid DMF submitted to regulatory agencies in the US is known as a USDMF. L-Tartaric Acid USDMF includes data on L-Tartaric Acid's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The L-Tartaric Acid USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of L-Tartaric Acid suppliers with USDMF on PharmaCompass.

L-Tartaric Acid GMP

L-Tartaric Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of L-Tartaric Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right L-Tartaric Acid GMP manufacturer or L-Tartaric Acid GMP API supplier for your needs.

L-Tartaric Acid CoA

A L-Tartaric Acid CoA (Certificate of Analysis) is a formal document that attests to L-Tartaric Acid's compliance with L-Tartaric Acid specifications and serves as a tool for batch-level quality control.

L-Tartaric Acid CoA mostly includes findings from lab analyses of a specific batch. For each L-Tartaric Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

L-Tartaric Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (L-Tartaric Acid EP), L-Tartaric Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (L-Tartaric Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

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