DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Virtual Booth

Contact Supplier

Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

2 API Suppliers, 2 USDMF

2 API Suppliers
2 USDMF

FINISHED DOSAGE FORMULATIONS

1 FDF Dossiers, 1 FDA Orange Book

1 FDF Dossiers
1 FDA Orange Book

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Laam hydrochloride, Levomethadyl acetate hcl, 43033-72-3, L-alpha-acetylmethadol hydrochloride, Levomethadyl acetate hydrochloride [usan], Mk790

Molecular Formula

C₂₃H₃₂ClNO₂

Molecular Weight

390.0 g/mol

InChI Key

UXBPQRGCVJOTNT-COBSGTNCSA-N

FDA UNII

B54CW5KG52

A narcotic analgesic with a long onset and duration of action.

1 2D Structure

Laam Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

[(3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] acetate;hydrochloride

2.1.2 InChI

InChI=1S/C23H31NO2.ClH/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21;/h7-16,18,22H,6,17H2,1-5H3;1H/t18-,22-;/m0./s1

2.1.3 InChI Key

UXBPQRGCVJOTNT-COBSGTNCSA-N

2.1.4 Canonical SMILES

CCC(C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C.Cl

2.1.5 Isomeric SMILES

CC[C@@H](C(C[C@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C.Cl

2.2 Other Identifiers

2.2.1 UNII

B54CW5KG52

2.3 Synonyms

2.3.1 MeSH Synonyms

1. (3r,6r)-3-acetoxy-6-dimethylamino-4,4-diphenylheptane

2. 6-(dimethylamino)-4,4-diphenyl-3-heptanol Acetate

3. Acemethadone

4. Acetylmethadol

5. Alphacetylmethadol

6. Amidolacetate

7. Dimepheptanol

8. Laam

9. Levo Alpha Acetylmethadol

10. Levo-alpha-acetylmethadol

11. Levoacetylmethadol

12. Levomethadyl

13. Levomethadyl Acetate

14. Methadol

15. Methadyl Acetate

16. Orlaam

2.3.2 Depositor-Supplied Synonyms

1. Laam Hydrochloride

2. Levomethadyl Acetate Hcl

3. 43033-72-3

4. L-alpha-acetylmethadol Hydrochloride

5. Levomethadyl Acetate Hydrochloride [usan]

6. Mk790

7. B54cw5kg52

8. Mk-790

9. (-)-(3s,6s)-6-(dimethylamino)-4,4-diphenyl-3-heptanol Acetate (ester), Hydrochloride

10. (3s,6s)-6-(dimethylamino)-4,4-diphenylheptan-3-yl Acetate Hydrochloride

11. L-acetylmethadol Hydrochloride

12. Levomethadyl Acetate Hydrochloride (usan)

13. Ccris 3321

14. Levacetyl Methadol Hydrochloride

15. Laam-hcl

16. Alpha-l-acetylmethadol Hydrochloride

17. Mk 790

18. Unii-b54cw5kg52

19. Levacetylmethadol Hydrochloride

20. Orlaam (tn)

21. Schembl79093

22. Mls002320666

23. 6-dimethylamino-4,4-diphenyl-3-heptanolacetate.hcl

24. Chebi:6442

25. Chembl1200817

26. Dtxsid7020500

27. (1s,4s)-4-(dimethylamino)-1-ethyl-2,2-diphenylpentyl Acetate Hydrochloride

28. 3-heptanol, 6-(dimethylamino)-4,4-diphenyl-, Acetate (ester), Hydrochloride, (3s,6s)-(-)-

29. Benzeneethanol, Beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, Acetate (ester), Hydrochloride, (s-(r*,r*))-

30. Smr001338812

31. Laam Hydrochloride, >=98% (hplc), Solid

32. D00840

33. Levacetylmethadol Hydrochloride [mart.]

34. Levomethadyl Acetate Hydrochloride [mi]

35. Levomethadyl Acetate Hydrochloride [vandf]

36. Levomethadyl Acetate Hydrochloride [who-dd]

37. Q27274386

38. Levomethadyl Acetate Hydrochloride [orange Book]

39. 6-dimethylamino-4,4-diphenyl-3-heptanol Acetate.hcl

40. [(3s,6s)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] Acetate;hydrochloride

41. Benzeneethanol, .beta.-(2-(dimethylamino)propyl)-.alpha.-ethyl-.beta.-phenyl-, Acetate (ester), Hydrochloride, (s-(r*,r*))-

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₂₃H₃₂ClNO₂
Molecular Weight	390.0 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	9
Exact Mass	389.2121570 g/mol
Monoisotopic Mass	389.2121570 g/mol
Topological Polar Surface Area	29.5 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	404
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Analgesics, Opioid

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)

API SUPPLIERS