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Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 927961-18-0, Iva-337, Iva337, 28q8ag0pyl, Chembl4091374, Cpd1537
Molecular Formula
C19H15ClN2O4S2
Molecular Weight
434.9  g/mol
InChI Key
OQDQIFQRNZIEEJ-UHFFFAOYSA-N
FDA UNII
28Q8AG0PYL

Lanifibranor
Lanifibranor is under investigation in clinical trial NCT03008070 (Phase 2b Study in NASH to Assess IVA337).
1 2D Structure

Lanifibranor

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloroindol-2-yl]butanoic acid
2.1.2 InChI
InChI=1S/C19H15ClN2O4S2/c20-13-4-7-17-12(8-13)9-14(2-1-3-19(23)24)22(17)28(25,26)15-5-6-16-18(10-15)27-11-21-16/h4-11H,1-3H2,(H,23,24)
2.1.3 InChI Key
OQDQIFQRNZIEEJ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC2=C(C=C1S(=O)(=O)N3C4=C(C=C(C=C4)Cl)C=C3CCCC(=O)O)SC=N2
2.2 Other Identifiers
2.2.1 UNII
28Q8AG0PYL
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Iva337

2.3.2 Depositor-Supplied Synonyms

1. 927961-18-0

2. Iva-337

3. Iva337

4. 28q8ag0pyl

5. Chembl4091374

6. Cpd1537

7. 4-[1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloroindol-2-yl]butanoic Acid

8. 1h-indole-2-butanoic Acid, 1-(6-benzothiazolylsulfonyl)-5-chloro-

9. 5-chloro-1-((6-benzothiazolyl)sulfonyl)-1h-indole-2-butanoic Acid

10. 4-(1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl)butanoic Acid

11. 4-(1-(benzo[d]thiazol-6-ylsulfonyl)-5-chloro-1h-indol-2-yl)butanoic Acid

12. 4-[1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl]butanoic Acid

13. Lanifbranor

14. Libfranor

15. Lanifbranor [inn]

16. Lanifibranor(iva-337)

17. Lanifibranor [inn]

18. Unii-28q8ag0pyl

19. Lanifibranor [who-dd]

20. Schembl3528615

21. Amy16813

22. Cmb96118

23. Ex-a1511

24. Bdbm50244350

25. S8770

26. Akos037649312

27. Db14801

28. Sb18746

29. Ac-31451

30. Bs-17993

31. Hy-104049

32. Cs-0027586

33. A903382

34. Q27896056

35. 1-(6-benzothiazolylsulfonyl)-5-chloro-1h-indole-2-butanoic Acid

36. Bjb

37. Iva-337; Iva 337;4-(1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl)butanoic Acid;iva-337

2.4 Create Date
2012-11-30
3 Chemical and Physical Properties
Molecular Weight 434.9 g/mol
Molecular Formula C19H15ClN2O4S2
XLogP34.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass434.0161770 g/mol
Monoisotopic Mass434.0161770 g/mol
Topological Polar Surface Area126 Ų
Heavy Atom Count28
Formal Charge0
Complexity686
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

INTERMEDIATES SUPPLIERS

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01

LinkChem

China
Duphat
Not Confirmed
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LinkChem

China
Duphat
Not Confirmed
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CAS Number : 181124-40-3

End Use API : Lanifibranor

About The Company : LinkChem is a leading China headquartered CMO | CRO provider within the pharmaceutical industry. Our core focus includes: custom synthesis, process development,...

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ABOUT THIS PAGE

Lanifibranor Manufacturers

A Lanifibranor manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Lanifibranor, including repackagers and relabelers. The FDA regulates Lanifibranor manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Lanifibranor API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Lanifibranor Suppliers

A Lanifibranor supplier is an individual or a company that provides Lanifibranor active pharmaceutical ingredient (API) or Lanifibranor finished formulations upon request. The Lanifibranor suppliers may include Lanifibranor API manufacturers, exporters, distributors and traders.

Lanifibranor GMP

Lanifibranor Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Lanifibranor GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Lanifibranor GMP manufacturer or Lanifibranor GMP API supplier for your needs.

Lanifibranor CoA

A Lanifibranor CoA (Certificate of Analysis) is a formal document that attests to Lanifibranor's compliance with Lanifibranor specifications and serves as a tool for batch-level quality control.

Lanifibranor CoA mostly includes findings from lab analyses of a specific batch. For each Lanifibranor CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Lanifibranor may be tested according to a variety of international standards, such as European Pharmacopoeia (Lanifibranor EP), Lanifibranor JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Lanifibranor USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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