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ACTIVE PHARMA INGREDIENTS

20 API Suppliers, 8 USDMF, 4 NDC API, 15 Listed Suppliers, $ API Reference Price

20 API Suppliers
8 USDMF
4 NDC API
15 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

6 Drugs in Development

6 Drugs in Development

FINISHED DOSAGE FORMULATIONS

100 FDF Dossiers, 9 FDA Orange Book, 52 Europe, 3 Canada, 24 Australia, 3 South Africa, 9 Listed Dossiers

100 FDF Dossiers
9 FDA Orange Book
52 Europe
3 Canada
24 Australia
3 South Africa
9 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

SOLUTION;SUBCUTANEOUS - EQ 120MG BASE/0.5ML (EQ 120MG BASE/0.5ML), SOLUTION;SUBCUTANEOUS - EQ 60MG BASE/0.2ML (EQ 60MG BASE/0.2ML), SOLUTION;SUBCUTANEOUS - EQ 90MG BASE/0.3ML (EQ 90MG BASE/0.3ML), SOLUTION;SUBCUTANEOUS - EQ 120MG BASE/0.5ML (EQ 120MG BASE/0.5ML), SOLUTION;SUBCUTANEOUS - EQ 60MG BASE/0.2ML (EQ 60MG BASE/0.2ML), SOLUTION;SUBCUTANEOUS - EQ 90MG BASE/0.3ML (EQ 90MG BASE/0.3ML)

drugProductComposition
SOLUTION;SUBCUTANEOUS - EQ 120MG BASE/0.5ML (EQ 120MG BASE/0.5ML)
SOLUTION;SUBCUTANEOUS - EQ 60MG BASE/0.2ML (EQ 60MG BASE/0.2ML)
SOLUTION;SUBCUTANEOUS - EQ 90MG BASE/0.3ML (EQ 90MG BASE/0.3ML)
SOLUTION;SUBCUTANEOUS - EQ 120MG BASE/0.5ML (EQ 120MG BASE/0.5ML)
SOLUTION;SUBCUTANEOUS - EQ 60MG BASE/0.2ML (EQ 60MG BASE/0.2ML)
SOLUTION;SUBCUTANEOUS - EQ 90MG BASE/0.3ML (EQ 90MG BASE/0.3ML)

DIGITAL CONTENT

2 DATA COMPILATION #PharmaFlow, 18 NEWS #PharmaBuzz

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2 DATA COMPILATION #PharmaFlow
18 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

2 US Medicaid Prescriptions, 24 Finished Drug Prices, 10 Annual Reports

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2 US Medicaid Prescriptions
24 Finished Drug Prices
10 Annual Reports

MARKET PLACE

4 APIs, 5 FDF Dossiers

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4 APIs
5 FDF Dossiers

PATENTS & EXCLUSIVITIES

3 US Exclusivities, 6 Health Canada Patents

patents
3 US Exclusivities
6 Health Canada Patents

REF. STANDARDS & IMPURITIES

3 Others

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3 Others

Bachem Lanreotide Acetate

Synopsis

ACTIVE PHARMA INGREDIENTS

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API REF. PRICE (USD/KG)

$ 437,254

MARKET PLACE

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

100

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

6DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

51,305,967

Annual Reports (USD Million)

9,023

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Somatuline lp, Lanreotide (acetate), Bim-23014c, Ipstyl, Somatuline, Somatuline autogel

Molecular Formula

C₅₆H₇₃N₁₁O₁₂S₂

Molecular Weight

1156.4 g/mol

InChI Key

DEXPIBGCLCPUHE-UISHROKMSA-N

1 2D Structure

Lanreotide Acetate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

acetic acid;(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-19-[[(2R)-2-amino-3-naphthalen-2-ylpropanoyl]amino]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

2.1.2 InChI

InChI=1S/C54H69N11O10S2.C2H4O2/c1-29(2)45-54(75)63-44(53(74)65-46(30(3)66)47(57)68)28-77-76-27-43(62-48(69)38(56)23-32-15-18-33-10-4-5-11-34(33)22-32)52(73)60-41(24-31-16-19-36(67)20-17-31)50(71)61-42(25-35-26-58-39-13-7-6-12-37(35)39)51(72)59-40(49(70)64-45)14-8-9-21-55;1-2(3)4/h4-7,10-13,15-20,22,26,29-30,38,40-46,58,66-67H,8-9,14,21,23-25,27-28,55-56H2,1-3H3,(H2,57,68)(H,59,72)(H,60,73)(H,61,71)(H,62,69)(H,63,75)(H,64,70)(H,65,74);1H3,(H,3,4)/t30-,38-,40+,41+,42-,43+,44+,45+,46+;/m1./s1

2.1.3 InChI Key

DEXPIBGCLCPUHE-UISHROKMSA-N

2.1.4 Canonical SMILES

CC(C)C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC6=CC=CC=C6C=C5)N)C(=O)NC(C(C)O)C(=O)N.CC(=O)O

2.1.5 Isomeric SMILES

C[C@H]([C@@H](C(=O)N)NC(=O)[C@@H]1CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)C(C)C)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)[C@@H](CC5=CC6=CC=CC=C6C=C5)N)O.CC(=O)O

2.2 Synonyms

2.2.1 MeSH Synonyms

1. 188re-lanreotide

2. 2-naphthylalanyl-cyclo(cysteinyl-tyrosyl-tryptophyl-lysyl-valyl-cysteinyl)-threoninamide

3. 3-(2-naphthyl)-d-ala-cys-tyr-d-trp-lys-val-cys-thr-nh2

4. 3-(2-naphthyl)alanyl-cystinyl-tyrosyl-tryptophyl-lysyl-valyl-cystinyl-threonine Amide

5. Angiopeptin

6. Bim 23014

7. Bim 23014 C

8. Bim 23014c

9. Bim-23014

10. Bim-23014 C

11. D-nal-cys-tyr-trp-lys-val-cys-thr-nh2

12. Dc 13-116

13. Dc-13-116

14. Dc13-116

15. L-threoninamide, 3-(2-naphthalenyl)-d-alanyl-l-cysteinyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl-l-cysteinyl-, Cyclic (2-7)-disulfide

16. Lanreotide

17. Lanreotide Acetate

18. Lanreotide-sr

19. Nal-cyclo(cys-tyr-trp-lys-val-cys)-thr-nh2

20. Nal-cyclo(cys-tyr-trp-lys-val-cys)thr-nh2

21. Naphthalenyl-cyclo(cysteinyl-tyrosyl-tryptophyl-lysyl-valyl-cysteinyl)threoninamide

22. Naphthyl-cyclo(cys-tyr-trp-lys-val-cys)thr-nh2

23. Somatulin

24. Somatulina

25. Somatuline

2.2.2 Depositor-Supplied Synonyms

1. Somatuline Lp

2. Lanreotide (acetate)

3. Bim-23014c

4. Ipstyl

5. Somatuline

6. Somatuline Autogel

7. 2378114-72-6

8. Angiopeptin Acetate

9. Somatulina

10. Somatuline La

11. Acetic Acid;(4r,7s,10s,13r,16s,19r)-10-(4-aminobutyl)-n-[(2s,3r)-1-amino-3-hydroxy-1-oxobutan-2-yl]-19-[[(2r)-2-amino-3-naphthalen-2-ylpropanoyl]amino]-16-[(4-hydroxyphenyl)methyl]-13-(1h-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

12. Chembl1201184

13. Hy-p1959a

14. Itm-014

15. Mfcd00873576

16. Bn-52030

17. Dc13-116

18. Cs-0113779

19. P1088

2.3 Create Date

2006-07-28

3 Chemical and Physical Properties

Molecular Formula	C₅₆H₇₃N₁₁O₁₂S₂
Molecular Weight	1156.4 g/mol
Hydrogen Bond Donor Count	14
Hydrogen Bond Acceptor Count	16
Rotatable Bond Count	17
Exact Mass	1155.48815915 g/mol
Monoisotopic Mass	1155.48815915 g/mol
Topological Polar Surface Area	443 Å²
Heavy Atom Count	81
Formal Charge	0
Complexity	2030
Isotope Atom Count	0
Defined Atom Stereocenter Count	9
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Somatuline depot
PubMed Health	Lanreotide (Subcutaneous)
Drug Classes	Endocrine-Metabolic Agent
Drug Label	Somatuline Depot (lanreotide) Injection 60, 90 and 120 mg is a prolonged-release formulation for deep subcutaneous injection containing the drug substance lanreotide acetate, a synthetic octapeptide with a biological activity similar to naturally occ...
Active Ingredient	Lanreotide acetate
Dosage Form	Injectable
Route	Subcutaneous
Strength	eq 90mg base; eq 120mg base; eq 60mg base
Market Status	Prescription
Company	Ipsen Pharma

2 of 2
Drug Name	Somatuline depot
PubMed Health	Lanreotide (Subcutaneous)
Drug Classes	Endocrine-Metabolic Agent
Drug Label	Somatuline Depot (lanreotide) Injection 60, 90 and 120 mg is a prolonged-release formulation for deep subcutaneous injection containing the drug substance lanreotide acetate, a synthetic octapeptide with a biological activity similar to naturally occ...
Active Ingredient	Lanreotide acetate
Dosage Form	Injectable
Route	Subcutaneous
Strength	eq 90mg base; eq 120mg base; eq 60mg base
Market Status	Prescription
Company	Ipsen Pharma

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Antineoplastic Agents

Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)

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API Reference Price

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