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Lasmiditan

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ACTIVE PHARMA INGREDIENTS

12 API Suppliers, 4 USDMF, 1 KDMF, 2 NDC API, 10 Listed Suppliers, $ API Reference Price

12 API Suppliers
4 USDMF
1 KDMF
2 NDC API
10 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

8 Drugs in Development

8 Drugs in Development

INTERMEDIATES

1 Intermediates Suppliers

1 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

3 FDF Dossiers, 3 FDA Orange Book

3 FDF Dossiers
3 FDA Orange Book

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 16 NEWS #PharmaBuzz

media
1 DATA COMPILATION #PharmaFlow
16 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions

globalSalesInformation
1 US Medicaid Prescriptions

MARKET PLACE

6 APIs

marketPlace
6 APIs

PATENTS & EXCLUSIVITIES

8 US Patents, 3 US Exclusivities

patents
8 US Patents
3 US Exclusivities

Metrochem LASMIDITAN

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

8,278,681

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Lasmiditan hemisuccinate, 439239-92-6, Lasmiditan succinate [usan], Ly683974, W64ybj346b, 439239-92-6 (succinate)

Molecular Formula

C₄₂H₄₂F₆N₆O₈

Molecular Weight

872.8 g/mol

InChI Key

MSOIHUHNGPOCTH-UHFFFAOYSA-N

FDA UNII

W64YBJ346B

1 2D Structure

Lasmiditan

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

butanedioic acid;2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl]benzamide

2.1.2 InChI

InChI=1S/2C19H18F3N3O2.C4H6O4/c2*1-25-7-5-11(6-8-25)18(26)15-3-2-4-16(23-15)24-19(27)17-13(21)9-12(20)10-14(17)22;5-3(6)1-2-4(7)8/h2*2-4,9-11H,5-8H2,1H3,(H,23,24,27);1-2H2,(H,5,6)(H,7,8)

2.1.3 InChI Key

MSOIHUHNGPOCTH-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F.CN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F.C(CC(=O)O)C(=O)O

2.2 Other Identifiers

2.2.1 UNII

W64YBJ346B

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2,4,6-trifluoro-n-(6-((1-methylpiperidin-4-yl)carbonyl)pyridin-2yl)benzamide

2. Col-144

3. Lasmiditan

4. Lasmiditan Hydrochloride

5. Ly573144

6. Reyvow

2.3.2 Depositor-Supplied Synonyms

1. Lasmiditan Hemisuccinate

2. 439239-92-6

3. Lasmiditan Succinate [usan]

4. Ly683974

5. W64ybj346b

6. 439239-92-6 (succinate)

7. Reyvow

8. Ly-573144

9. Ly-683974

10. 2,4,6-trifluoro-n-(6-((1-methylpiperidine-4-yl)carbonyl)pyridin-2-yl)benzamide Hemisuccinate

11. 2,4,6-trifluoro-n-(6-((1-methylpiperidine-4-yl)carbonyl)pyridin-2-yl)benzamide Succinic (2:1)

12. Unii-w64ybj346b

13. Reyvow (tn)

14. Chembl3039526

15. Dtxsid10195991

16. Lasmiditan Succinate (jan/usan)

17. Lasmiditan Succinate [jan]

18. Ex-a1654

19. Lasmiditan Hemisuccinate [mi]

20. S6489

21. Lasmiditan Succinate [who-dd]

22. Ac-30917

23. Bl166745

24. Lasmiditan Succinate [orange Book]

25. D10424

26. Q27292373

27. Butanedioic Acid;2,4,6-trifluoro-n-[6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl]benzamide

2.4 Create Date

2010-11-01

3 Chemical and Physical Properties

Molecular Formula	C₄₂H₄₂F₆N₆O₈
Molecular Weight	872.8 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	18
Rotatable Bond Count	11
Exact Mass	872.29683129 g/mol
Monoisotopic Mass	872.29683129 g/mol
Topological Polar Surface Area	199 Å²
Heavy Atom Count	62
Formal Charge	0
Complexity	623
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3

4 Drug and Medication Information

4.1 Drug Indication

RAYVOW is indicated for the acute treatment of the headache phase of migraine attacks, with or without aura in adults.

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Serotonin Receptor Agonists

Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. (See all compounds classified as Serotonin Receptor Agonists.)

5.2 ATC Code

N02CC08

API SUPPLIERS

01

Metrochem API Private Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

DDL Conference

Not Confirmed

Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

02

Moehs Iberica

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI WW Frankfurt

Booth #11.0C6

Moehs Group, a reference company in the production of pharmaceutical active ingredients.

Contact Supplier

Spain

Virtual Booth

Digital Content

USDMF

CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

03

Hubei Gedian Humanwell Pharmaceuti...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

DDL Conference

Not Confirmed

Hubei Gedian Humanwell focuses on R&D, production, & sales of fertility regulation drugs & steroidal APIs.

Contact Supplier

China

Virtual Booth

Digital Content

USDMF

CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

04

Shanghai Desano Chemical Pharmaceu...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

DDL Conference

Not Confirmed

05

Shandong Anhong Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

DDL Conference

Not Confirmed

06

UQUIFA

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

DDL Conference

Not Confirmed

07

Mankind Pharma

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

DDL Conference

Not Confirmed

08

Suzhou Biosyntech

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

DDL Conference

Not Confirmed

09

Glenmark Pharmaceuticals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

DDL Conference

Not Confirmed

10

Zhejiang Tianyu Pharmaceutical Co....

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

DDL Conference

Not Confirmed

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USDMF

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KDMF

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NDC API

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Listed Suppliers

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API Reference Price

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