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Lasmiditan

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ACTIVE PHARMA INGREDIENTS

13 API Suppliers, 4 USDMF, 1 KDMF, 2 NDC API, 11 Listed Suppliers, $ API Reference Price

13 API Suppliers
4 USDMF
1 KDMF
2 NDC API
11 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

8 Drugs in Development

8 Drugs in Development

INTERMEDIATES

1 Intermediates Suppliers

1 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

3 FDF Dossiers, 3 FDA Orange Book

3 FDF Dossiers
3 FDA Orange Book

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 16 NEWS #PharmaBuzz

media
1 DATA COMPILATION #PharmaFlow
16 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions

globalSalesInformation
1 US Medicaid Prescriptions

MARKET PLACE

6 APIs

marketPlace
6 APIs

PATENTS & EXCLUSIVITIES

8 US Patents, 3 US Exclusivities

patents
8 US Patents
3 US Exclusivities

Metrochem LASMIDITAN

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

8,278,681

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Lasmiditan hemisuccinate, 439239-92-6, Lasmiditan succinate [usan], Ly683974, W64ybj346b, 439239-92-6 (succinate)

Molecular Formula

C₄₂H₄₂F₆N₆O₈

Molecular Weight

872.8 g/mol

InChI Key

MSOIHUHNGPOCTH-UHFFFAOYSA-N

FDA UNII

W64YBJ346B

1 2D Structure

Lasmiditan

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

butanedioic acid;2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl]benzamide

2.1.2 InChI

InChI=1S/2C19H18F3N3O2.C4H6O4/c2*1-25-7-5-11(6-8-25)18(26)15-3-2-4-16(23-15)24-19(27)17-13(21)9-12(20)10-14(17)22;5-3(6)1-2-4(7)8/h2*2-4,9-11H,5-8H2,1H3,(H,23,24,27);1-2H2,(H,5,6)(H,7,8)

2.1.3 InChI Key

MSOIHUHNGPOCTH-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F.CN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F.C(CC(=O)O)C(=O)O

2.2 Other Identifiers

2.2.1 UNII

W64YBJ346B

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2,4,6-trifluoro-n-(6-((1-methylpiperidin-4-yl)carbonyl)pyridin-2yl)benzamide

2. Col-144

3. Lasmiditan

4. Lasmiditan Hydrochloride

5. Ly573144

6. Reyvow

2.3.2 Depositor-Supplied Synonyms

1. Lasmiditan Hemisuccinate

2. 439239-92-6

3. Lasmiditan Succinate [usan]

4. Ly683974

5. W64ybj346b

6. 439239-92-6 (succinate)

7. Reyvow

8. Ly-573144

9. Ly-683974

10. 2,4,6-trifluoro-n-(6-((1-methylpiperidine-4-yl)carbonyl)pyridin-2-yl)benzamide Hemisuccinate

11. 2,4,6-trifluoro-n-(6-((1-methylpiperidine-4-yl)carbonyl)pyridin-2-yl)benzamide Succinic (2:1)

12. Unii-w64ybj346b

13. Reyvow (tn)

14. Chembl3039526

15. Dtxsid10195991

16. Lasmiditan Succinate (jan/usan)

17. Lasmiditan Succinate [jan]

18. Ex-a1654

19. Lasmiditan Hemisuccinate [mi]

20. S6489

21. Lasmiditan Succinate [who-dd]

22. Ac-30917

23. Bl166745

24. Lasmiditan Succinate [orange Book]

25. D10424

26. Q27292373

27. Butanedioic Acid;2,4,6-trifluoro-n-[6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl]benzamide

2.4 Create Date

2010-11-01

3 Chemical and Physical Properties

Molecular Formula	C₄₂H₄₂F₆N₆O₈
Molecular Weight	872.8 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	18
Rotatable Bond Count	11
Exact Mass	872.29683129 g/mol
Monoisotopic Mass	872.29683129 g/mol
Topological Polar Surface Area	199 Å²
Heavy Atom Count	62
Formal Charge	0
Complexity	623
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3

4 Drug and Medication Information

4.1 Drug Indication

RAYVOW is indicated for the acute treatment of the headache phase of migraine attacks, with or without aura in adults.

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Serotonin Receptor Agonists

Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. (See all compounds classified as Serotonin Receptor Agonists.)

5.2 ATC Code

N02CC08

API SUPPLIERS

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USDMF

01

Moehs Iberica Sl

Spain

CPhI WW Frankfurt

Booth #11.0C6

Moehs Group, a reference company in the production of pharmaceutical active ingredients.

Contact Supplier

Spain

Virtual Booth

Digital Content

Lasmiditan Hemisuccinate

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 38222

Submission : 2023-03-27

Status : Active

Type : II

02

Hubei Gedian Humanwell Pharmaceutica...

China

CPhI India 2024

Attending

Hubei Gedian Humanwell focuses on R&D, production, & sales of fertility regulation drugs & steroidal APIs.

Contact Supplier

China

Virtual Booth

Digital Content

Lasmiditan Hemisuccinate

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 40130

Submission : 2024-07-27

Status : Active

Type : II

03

Shandong Anhong Pharmaceutical Co Lt...

China

euroPLX 86 Munich

Not Confirmed

04

Shanghai Desano Chemical Pharmaceuti...

China

euroPLX 86 Munich

Not Confirmed

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KDMF

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NDC API

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Listed Suppliers

01

Metrochem API Private Limited

India

Pharmtech & Ingredients

Exhibiting

Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

Contact Supplier

India

Virtual Booth

Digital Content

Lasmiditan

About the Company :

Established in 2004, Metrochem API is one of the fastest-growing APIs, pellets & intermediates manufacturers. It has 6 dedicated manufacturing facilities for its 3 core product ...

Established in 2004, Metrochem API is one of the fastest-growing APIs, pellets & intermediates manufacturers. It has 6 dedicated manufacturing facilities for its 3 core product groups and has been approved by ISO 9001-2015, USFDA, WHO GMP, Cofepris & Japanese authorities. Metrochem’s in-depth industry knowledge, & hi-tech & advanced infrastructure, helps it provide quality products to its customers. Note: None of the products will be supplied to the countries where this could conflict with existing patents. Further, any products under patent will be offered for R&D purposes only. However, the final responsibility lies with the buyer

02

Moehs Iberica

Spain

CPhI WW Frankfurt

Booth #11.0C6

Moehs Group, a reference company in the production of pharmaceutical active ingredients.

Contact Supplier

Spain

Virtual Booth

Digital Content

Lasmiditan Succinate

About the Company : Since its founding in 1962, MOEHS has produced Active Pharmaceutical Ingredients (APIs) for the international pharmaceutical industry. Thanks to a business history of more than 50 ...

Since its founding in 1962, MOEHS has produced Active Pharmaceutical Ingredients (APIs) for the international pharmaceutical industry. Thanks to a business history of more than 50 years, MOEHS has considerable technical experience in the production of these substances. At Moehs Group we have a large tradition and experience in the area of manufacturing of active pharmaceutical and veterinary ingredients, agrochemicals, nutraceutical, cosmetic, as well as fine chemistry in general, with high levels of quality and safety standards-GMP´s, ICH, approved by the FDA and TGA.

03

Hubei Gedian Humanwell Pharmaceutic...

China

CPhI India 2024

Attending

Hubei Gedian Humanwell focuses on R&D, production, & sales of fertility regulation drugs & steroidal APIs.

Contact Supplier

China

Virtual Booth

Digital Content

Lasmiditan Succinate

About the Company : Hubei Gedian Humanwell Pharmaceutical Co., Ltd. is a modern high-tech pharmaceutical company with a focus on the research and development, production, and sales of fertility regula...

Hubei Gedian Humanwell Pharmaceutical Co., Ltd. is a modern high-tech pharmaceutical company with a focus on the research and development, production, and sales of fertility regulation drugs and steroidal APIs. It operates as a wholly-owned subsidiary of Humanwell Healthcare Group (Stock Code: 600079), one of the leading pharmaceutical conglomerates in China. The company operates two APIs manufacturing sites, one formulation factory, and one excipients factory, showcasing its commitment to integrating the reproductive health industry chain from raw materials and active pharmaceutical ingredients (APIs) to finished dosage forms.

04

Glenmark Pharmaceuticals

India

Spain

American Pharma Summit

Not Confirmed

Only 10 entries up to this point, click to access all

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API Reference Price

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