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Lasmiditan Succinate

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14 API Suppliers, 2 USDMF, 1 KDMF, 2 NDC API, 13 Listed Suppliers, $ API Reference Price

14 API Suppliers
2 USDMF
1 KDMF
2 NDC API
13 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

8 Drugs in Development

8 Drugs in Development

INTERMEDIATES

2 Intermediates Suppliers

2 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

3 FDF Dossiers, 3 FDA Orange Book

3 FDF Dossiers
3 FDA Orange Book

DIGITAL CONTENT

16 NEWS #PharmaBuzz

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16 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions

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1 US Medicaid Prescriptions

MARKET PLACE

6 APIs

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6 APIs

PATENTS & EXCLUSIVITIES

6 US Patents, 3 US Exclusivities

patents
6 US Patents
3 US Exclusivities

Metrochem LASMIDITAN

Synopsis

ACTIVE PHARMA INGREDIENTS

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EU WC

KDMF

NDC API

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API REF. PRICE (USD/KG)

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US Patents

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Health Canada Patents

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Data Compilation #PharmaFlow

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GLOBAL SALES INFORMATION

US Medicaid (USD)

8,278,681

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Finished Drug Prices

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Chemistry

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Also known as: Lasmiditan hemisuccinate, 439239-92-6, Lasmiditan succinate [usan], Ly683974, W64ybj346b, 439239-92-6 (succinate)

Molecular Formula

C₄₂H₄₂F₆N₆O₈

Molecular Weight

872.8 g/mol

InChI Key

MSOIHUHNGPOCTH-UHFFFAOYSA-N

FDA UNII

W64YBJ346B

1 2D Structure

Lasmiditan

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

butanedioic acid;2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl]benzamide

2.1.2 InChI

InChI=1S/2C19H18F3N3O2.C4H6O4/c2*1-25-7-5-11(6-8-25)18(26)15-3-2-4-16(23-15)24-19(27)17-13(21)9-12(20)10-14(17)22;5-3(6)1-2-4(7)8/h2*2-4,9-11H,5-8H2,1H3,(H,23,24,27);1-2H2,(H,5,6)(H,7,8)

2.1.3 InChI Key

MSOIHUHNGPOCTH-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F.CN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F.C(CC(=O)O)C(=O)O

2.2 Other Identifiers

2.2.1 UNII

W64YBJ346B

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2,4,6-trifluoro-n-(6-((1-methylpiperidin-4-yl)carbonyl)pyridin-2yl)benzamide

2. Col-144

3. Lasmiditan

4. Lasmiditan Hydrochloride

5. Ly573144

6. Reyvow

2.3.2 Depositor-Supplied Synonyms

1. Lasmiditan Hemisuccinate

2. 439239-92-6

3. Lasmiditan Succinate [usan]

4. Ly683974

5. W64ybj346b

6. 439239-92-6 (succinate)

7. Reyvow

8. Ly-573144

9. Ly-683974

10. 2,4,6-trifluoro-n-(6-((1-methylpiperidine-4-yl)carbonyl)pyridin-2-yl)benzamide Hemisuccinate

11. 2,4,6-trifluoro-n-(6-((1-methylpiperidine-4-yl)carbonyl)pyridin-2-yl)benzamide Succinic (2:1)

12. Unii-w64ybj346b

13. Reyvow (tn)

14. Chembl3039526

15. Dtxsid10195991

16. Lasmiditan Succinate (jan/usan)

17. Lasmiditan Succinate [jan]

18. Ex-a1654

19. Lasmiditan Hemisuccinate [mi]

20. S6489

21. Lasmiditan Succinate [who-dd]

22. Ac-30917

23. Bl166745

24. Lasmiditan Succinate [orange Book]

25. D10424

26. Q27292373

27. Butanedioic Acid;2,4,6-trifluoro-n-[6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl]benzamide

2.4 Create Date

2010-11-01

3 Chemical and Physical Properties

Molecular Formula	C₄₂H₄₂F₆N₆O₈
Molecular Weight	872.8 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	18
Rotatable Bond Count	11
Exact Mass	872.29683129 g/mol
Monoisotopic Mass	872.29683129 g/mol
Topological Polar Surface Area	199 Å²
Heavy Atom Count	62
Formal Charge	0
Complexity	623
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3

4 Drug and Medication Information

4.1 Drug Indication

RAYVOW is indicated for the acute treatment of the headache phase of migraine attacks, with or without aura in adults.

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Serotonin Receptor Agonists

Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. (See all compounds classified as Serotonin Receptor Agonists.)

5.2 ATC Code

N02CC08

API SUPPLIERS

01

Metrochem API Private Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3A33

Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

02

Inke S.A

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3A105

Inke S.A: APIs manufacturing plant.

Contact Supplier

Spain

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

03

Moehs Iberica

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #4A33

Moehs Group, a reference company in the production of pharmaceutical active ingredients.

Contact Supplier

Spain

Virtual Booth

Digital Content

USDMF

CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

04

Hubei Gedian Humanwell Pharmaceuti...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3A65

Hubei Gedian Humanwell focuses on R&D, production, & sales of fertility regulation drugs & steroidal APIs.

Contact Supplier

China

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

05

Shandong Anhong Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

06

Olon S.p.A

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

07

Zhejiang Tianyu Pharmaceutical Co....

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

08

Glenmark Pharmaceuticals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

09

Teva API

Israel

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

10

Mankind Pharma

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

Only 10 entries up to this point, click to access all

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USDMF

01

Moehs Iberica Sl

Spain

CPhI Worldwide, Milan

Booth #4A33

Moehs Group, a reference company in the production of pharmaceutical active ingredients.

Contact Supplier

Spain

Virtual Booth

Digital Content

Lasmiditan Hemisuccinate

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 38222

Submission : 2023-03-27

Status : Active

Type : II

02

Shandong Anhong Pharmaceutical Co Lt...

China

Discovery on Target

Not Confirmed

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KDMF

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NDC API

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Listed Suppliers

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API Reference Price

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L","address":"PLOT NO 74\/A JNPC,THANAM VILLAGE P ARAWADA MANDAL","city":"VISAKHAPATNAM,ANDHRA PRADESH","supplier":"JPR LABS PRIVATE ","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"GLOBAL NAPI PHARMACEUTICALS","customerCountry":"EGYPT","quantity":"0.25","actualQuantity":"250","unit":"GMS","unitRateFc":"8","totalValueFC":"1707.9","currency":"USD","unitRateINR":528,"date":"05-May-2022","totalValueINR":"132000","totalValueInUsd":"1707.9","indian_port":"HYDERABAD AIR","hs_no":"29339910","bill_no":"1185567","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"PLOT NO 74\/A JNPC,THANAM VILLAGE P ARAWADA MANDAL, VISAKHAPATNAM,ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1685212200,"product":"LASMIDITAN HEMISUCCINATE IH","address":"3 BOTAWALA BLDG 1ST FLOOR,BANK STR EET BEHIND SBI FORT","city":"MUMBAI,MAHARASHTRA","supplier":"NISHCHEM INTERNATIONAL PVT. LTD","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"TO THE ORDER OF NATIONAL HEALTHCARE","customerCountry":"NEPAL","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"160000","totalValueFC":"1944.5","currency":"INR","unitRateINR":160000,"date":"28-May-2023","totalValueINR":"160000","totalValueInUsd":"1944.5","indian_port":"RAXAUL","hs_no":"29339990","bill_no":"0","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"RAXAUL","supplierAddress":"3 BOTAWALA BLDG 1ST FLOOR,BANK STR EET BEHIND SBI FORT, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1689791400,"product":"LASMIDITAN HEMISUCCINATE IHS","address":"7-1-638 TO 643, 643\/1,FLAT NO. 302 ,,BHANU ENCLAVE, ERRAGADDA","city":"HYDERABAD,TELANGANA","supplier":"METROCHEM API PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"KARACHI -","customer":"TO THE OREDR OF .","customerCountry":"PAKISTAN","quantity":"1.80","actualQuantity":"1.8","unit":"KGS","unitRateFc":"2800","totalValueFC":"4952","currency":"USD","unitRateINR":226110.88499999998,"date":"20-Jul-2023","totalValueINR":"406999.593","totalValueInUsd":"4952","indian_port":"HYDERABAD AIR","hs_no":"29339990","bill_no":"0","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"7-1-638 TO 643, 643\/1,FLAT NO. 302 ,,BHANU ENCLAVE, ERRAGADDA, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1694370600,"product":"PHARMACEUTICALS RAW MATERIALS: LASMIDITAN HEMISUCCINATE BATCH NO LAS-P\/23001","address":"FLAT NO.302, BHANU ENCLAVE","city":"HYDERABAD.AP","supplier":"METROCHEM API PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"STANDARD CHARTERED BANK","customerCountry":"BANGLADESH","quantity":"3.50","actualQuantity":"3.5","unit":"KGS","unitRateFc":"2500","totalValueFC":"8167.9","currency":"USD","unitRateINR":193714.28571428571,"date":"11-Sep-2023","totalValueINR":"678000","totalValueInUsd":"8167.9","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"3839351","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"FLAT NO.302, BHANU ENCLAVE, HYDERABAD.AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1698345000,"product":"LASMIDITAN HEMISUCCINATE BATCH NO LAS-P\/23001,LAS-P\/23002","address":"FLAT NO.302, BHANU ENCLAVE","city":"HYDERABAD.AP","supplier":"METROCHEM API PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"HIKMA PHARMACEUTICALS","customerCountry":"EGYPT","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"3700","totalValueFC":"732.9","currency":"USD","unitRateINR":305000,"date":"27-Oct-2023","totalValueINR":"61000","totalValueInUsd":"732.9","indian_port":"Hyderabad Air","hs_no":"29420090","bill_no":"4935445","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"FLAT NO.302, BHANU ENCLAVE, HYDERABAD.AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1706121000,"product":"LASMIDITAN HEMISUCCINATE PHARMACEUTICALRAW MATERIALS METROCHEM BATCH NO: LAS-P\/23001","address":"FLAT NO.302, BHANU ENCLAVE","city":"HYDERABAD.AP","supplier":"METROCHEM API PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"NATIONAL CREDIT AND","customerCountry":"BANGLADESH","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"3750","totalValueFC":"11052.7","currency":"USD","unitRateINR":306204.16666666669,"date":"25-Jan-2024","totalValueINR":"918612.5","totalValueInUsd":"11052.7","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"7018667","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"FLAT NO.302, BHANU ENCLAVE, HYDERABAD.AP","customerAddress":""}]

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Drugs in Development

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Find listed supplier of Lasmiditan Succinate Active Pharmaceutical Ingredient on PharmaCompass.com

ACCESS ALL DATA

Browse all information

CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

14 API Suppliers

2 USDMF

1 KDMF

2 NDC API

13 Listed Suppliers

$ API Reference Price

DEVELOPMENTS

8 Drugs in Development

INTERMEDIATES

2 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

3 FDF Dossiers

3 FDA Orange Book

DIGITAL CONTENT

16 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions

MARKET PLACE

6 APIs

PATENTS & EXCLUSIVITIES

6 US Patents

3 US Exclusivities

ACTIVE PHARMA INGREDIENTS

API REF. PRICE (USD/KG)

$ 3,857

MARKET PLACE

FINISHED DOSAGE FORMULATIONS

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

GLOBAL SALES INFORMATION

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

01

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