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ACTIVE PHARMA INGREDIENTS

2 API Suppliers, 2 USDMF, $ API Reference Price

2 API Suppliers
2 USDMF
$ API Reference Price

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Chemistry

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Also known as: 24678-13-5, Lenperonum, Ahr-2277 [as hydrochloride], 13p4gx22es, 4'-fluoro-4-(4-(p-fluorobenzoyl)piperidino)butyrophenone, Ahr 2277

Molecular Formula

C₂₂H₂₃F₂NO₂

Molecular Weight

371.4 g/mol

InChI Key

WCIBOXFOUGQLFC-UHFFFAOYSA-N

FDA UNII

13P4GX22ES

1 2D Structure

Lenperone

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-[4-(4-fluorobenzoyl)piperidin-1-yl]-1-(4-fluorophenyl)butan-1-one

2.1.2 InChI

InChI=1S/C22H23F2NO2/c23-19-7-3-16(4-8-19)21(26)2-1-13-25-14-11-18(12-15-25)22(27)17-5-9-20(24)10-6-17/h3-10,18H,1-2,11-15H2

2.1.3 InChI Key

WCIBOXFOUGQLFC-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1CN(CCC1C(=O)C2=CC=C(C=C2)F)CCCC(=O)C3=CC=C(C=C3)F

2.2 Other Identifiers

2.2.1 UNII

13P4GX22ES

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 4'-fluoro-4-(4-(p-fluorobenozyl)piperidino)butyrophenone

2. Ahr 2277

3. Ahr-2277

4. Lenperone Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 24678-13-5

2. Lenperonum

3. Ahr-2277 [as Hydrochloride]

4. 13p4gx22es

5. 4'-fluoro-4-(4-(p-fluorobenzoyl)piperidino)butyrophenone

6. Ahr 2277

7. Chembl316004

8. 1-butanone, 4-(4-(4-fluorobenzoyl)-1-piperidinyl)-1-(4-fluorophenyl)-

9. 4-(4-(4-fluorobenzoyl)-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone

10. Lenperone (usan)

11. Ncgc00160383-01

12. Lenperone [usan]

13. 4-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one

14. Lenperonum [latin]

15. Lenperona [spanish]

16. Lenperona

17. Lenperone [usan:inn]

18. Lenperonum [inn-latin]

19. 4-(4-(4-fluorobenzoyl)piperidin-1-yl)-1-(4-fluorophenyl)butan-1-one

20. 4-[4-(4-fluorobenzoyl)-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone

21. 4-[4-(4-fluorobenzoyl)piperidin-1-yl]-1-(4-fluorophenyl)butan-1-one

22. Lenperona [inn-spanish]

23. 1-butanone, 4-[4-(4-fluorobenzoyl)-1-piperidinyl]-1-(4-fluorophenyl)-

24. Ahr2277

25. Nsc303301

26. Einecs 246-399-7

27. Brn 1554429

28. Unii-13p4gx22es

29. Lenperone [inn]

30. Lenperone [who-dd]

31. Dsstox_cid_26120

32. Dsstox_rid_81356

33. Dsstox_gsid_46120

34. 5-21-08-00146 (beilstein Handbook Reference)

35. Mls001205808

36. Schembl121686

37. Ahr-2277 Free Base

38. Dtxsid7046120

39. Hms2834c09

40. Zinc537887

41. Tox21 111775

42. Tox21_111775

43. Bdbm50004320

44. Ncgc00160383-02

45. Lenperone Hydrochloride (*hydrochloride*)

46. Smr000504164

47. Cas-24678-13-5

48. Ft-0670760

49. D02668

50. Q6523202

51. Butyrophenone, 4'-fluoro-4-[4-(p-fluorobenzoyl)piperidino]-

52. 1-(4-fluorophenyl)-4-(4-(4-fluorobenzoyl)piperidino)-1-butanone

53. 4-[4-(4-fluorobenzoyl)-1-piperidyl]-1-(4-fluorophenyl)butan-1-one

54. 1-(4-fluorophenyl)-4-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}butan-1-one

55. 1-butanone, {4-[4-(4-fluorobenzoyl)-1-piperidinyl]-1-(4-fluorophenyl)-,} Hydrochloride

56. Butyrophenone, {4'-fluoro-4-[4-(p-fluorobenzoyl)piperidino]-,} Hydrochloride

2.4 Create Date

2005-03-26

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₂₃F₂NO₂
Molecular Weight	371.4 g/mol
XLogP3	4
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	7
Exact Mass	371.16968530 g/mol
Monoisotopic Mass	371.16968530 g/mol
Topological Polar Surface Area	37.4 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	489
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1