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Also known as: Calcium folinate, Calcium citrovorum factor, Folinic acid calcium salt, Folinic acid-sf, calcium salt, (+)-l-folinic acid, calcium salt, 1492-18-8
Molecular Formula
C20H23CaN7O7+2
Molecular Weight
513.5  g/mol
InChI Key
KVUAALJSMIVURS-ZEDZUCNESA-N

Calcium Folinate
The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.
1 2D Structure

Calcium Folinate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
calcium;(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
2.1.2 InChI
InChI=1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/t12?,13-;/m0./s1
2.1.3 InChI Key
KVUAALJSMIVURS-ZEDZUCNESA-N
2.1.4 Canonical SMILES
C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O.[Ca+2]
2.1.5 Isomeric SMILES
C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O.[Ca+2]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 5 Formyltetrahydrofolate

2. 5 Formyltetrahydropteroylglutamate

3. 5-formyltetrahydrofolate

4. 5-formyltetrahydropteroylglutamate

5. Acid, Folinic

6. Calcium Folinate

7. Citrovorum Factor

8. Factor, Citrovorum

9. Folinate, Calcium

10. Folinic Acid

11. Folinic Acid Sf

12. Folinic Acid-sf

13. Leucovorin

14. Leucovorin, (d)-isomer

15. Leucovorin, (dl)-isomer

16. Leucovorin, (r)-isomer

17. Leucovorin, Calcium

18. Leucovorin, Calcium (1:1) Salt

19. Leucovorin, Calcium (1:1) Salt, (dl)-isomer

20. Leucovorin, Calcium (1:1) Salt, Pentahydrate

21. Leucovorin, Monosodium Salt

22. Leukovorin

23. Leukovorum

24. Monosodium Salt Leucovorin

25. N(5)-formyltetrahydrofolate

26. Wellcovorin

2.2.2 Depositor-Supplied Synonyms

1. Calcium Folinate

2. Calcium Citrovorum Factor

3. Folinic Acid Calcium Salt

4. Folinic Acid-sf, Calcium Salt

5. (+)-l-folinic Acid, Calcium Salt

6. 1492-18-8

7. Nsc3590

8. Sr-05000001662

9. Pharmakon1600-01500364

10. Nsc757083

11. Nsc-757083

12. Sr-05000001662-1

13. Sr-05000001662-2

14. Glutamic Acid,6,7,8-tetrahydro-4-hydroxy-6- Pteridinyl)methyl]amino]benzoyl]-, Calcium Salt (1:1), L-

15. L-glutamic Acid,4,5,6,7,8-hexahydro-4-oxo-6- Pteridinyl)methyl]amino]benzoyl]-, Calcium Salt (1:1), (s)-

2.3 Create Date
2019-01-15
3 Chemical and Physical Properties
Molecular Weight 513.5 g/mol
Molecular Formula C20H23CaN7O7+2
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count10
Rotatable Bond Count9
Exact Mass513.1284869 g/mol
Monoisotopic Mass513.1284869 g/mol
Topological Polar Surface Area216 Ų
Heavy Atom Count35
Formal Charge2
Complexity911
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antidotes

Agents counteracting or neutralizing the action of POISONS. (See all compounds classified as Antidotes.)


Vitamin B Complex

A group of water-soluble vitamins, some of which are COENZYMES. (See all compounds classified as Vitamin B Complex.)


4.2 ATC Code

V - Various

V03 - All other therapeutic products

V03A - All other therapeutic products

V03AF - Detoxifying agents for antineoplastic treatment

V03AF03 - Calcium folinate


API SUPPLIERS

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Listed Suppliers

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01

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Virtual BoothRochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

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Calcium Folinate

About the Company : Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quali...

Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quality ingredients manufactured in China. Headquartered in the Hauppauge, New York, Rochem has 16 offices spread across the globe to cater to the needs of its customers. Rochem’s operations are fully cGMP compliant and has been audited by the USFDA as well as several multinational organizations. It also trains and audits its partners to ensure all of their technologies and systems are FDA-compliant.
Rochem

02

Allastir

India
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Allastir

India
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Leucovorin Calcium

About the Company : Allastir instituted the services in 2010 with a motive to cater the pharmaceutical industry with niche API's. In Allastir we strongly believe in team work and customer satisfaction...

Allastir instituted the services in 2010 with a motive to cater the pharmaceutical industry with niche API's. In Allastir we strongly believe in team work and customer satisfaction. Allastir is backed by the strong R&D team who are passionate about what they do. We manufacture niche API's with high quality which are suitable for formulations like tablets, capsules, soft gelatins and oral liquids.To be the larder to develop innovative niche molecule to the health care industry for the betterment of human life.Our Vision is to be the Number ONE company in Health care Industry in the World.
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03

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Calcium Folinate

About the Company : Anthem Biosciences is a leading contract research and innovation service provider (CRISP) in Bengaluru, India, which manufactures novel drug actives. Established in 2007, it specia...

Anthem Biosciences is a leading contract research and innovation service provider (CRISP) in Bengaluru, India, which manufactures novel drug actives. Established in 2007, it specializes in both biological and chemistry-based products and services. It has a strong track record in drug and product development, and supports development, optimization and testing of various compounds including proteins, monoclonal antibodies, peptides, large & small molecules and toxins. Inspected by USFDA, Japan’s PMDA, EU QPs, it develops nutritional products using organic synthesis and offers quality control and regulatory compliance assistance to clients.
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04

Cerbios-Pharma SA

Switzerland
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Cerbios-Pharma SA

Switzerland
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Calcium Folinate

About the Company : Cerbios is a privately held company located in Lugano, Switzerland. Cerbios is the ideal CDMO partner from clinical to commercial supply of ADCs, HPAPIs, Proteins and Antibodies. ...

Cerbios is a privately held company located in Lugano, Switzerland. Cerbios is the ideal CDMO partner from clinical to commercial supply of ADCs, HPAPIs, Proteins and Antibodies. Services offered include Process & Analytical Development, Scale-up and Clinical Supply, Industrial Validation, Commercial Supply and Full CMC Regulatory Support. Cerbios supplies also generic APIs primarily used in Oncology, Respiratory and Dermatology. Cerbios has additionally a 40 years’ experience in the probiotics field: the portfolio includes a FDF based on proprietary strain SF68® for treatment of diarrhea & dysbiosis, ACNE & Seborrheic dermatitis.
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05

DEAFARMA

Italy
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DEAFARMA

Italy
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Calcium Folinate

About the Company : In the dinamic pharmaceutical field, DEAFARMA is the reference point for primaries Pharmaceutical Laboratories for over twenty years, even in the national and international territo...

In the dinamic pharmaceutical field, DEAFARMA is the reference point for primaries Pharmaceutical Laboratories for over twenty years, even in the national and international territory. DEAFARMA works with success in the pharmaceutical raw materials field through Agencies and professional relations with the most important European and Asiatic factories. Our partners are well known, reliable producers and all of them are operating in accordance with the latest GMP Rules. The APIs mentioned in the DEAFARMA catalogue are always supported by DMF and/or CEP.
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06

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Leucovorin Calcium

About the Company : As an EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979 as Calcium Ind...

As an EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979 as Calcium India. Today, Global Calcium represents the true hallmark of quality when it comes to pharmaceutical products. Global Calcium is backed by an excellent management team comprising of industry specialists, technocrats, entrepreneurs and business specialists bringing in strong domain expertise in fields such as investment banking, to consulting to behind the scenes pure sciences.
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07

American Pharma Summit
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Calcium Folinate

About the Company : HENGDIAN GROUP was established in 1975, till now it has become a transnational,conglomerate group and been one of the largest private-owned enterprises in China. The Pharmaceutical...

HENGDIAN GROUP was established in 1975, till now it has become a transnational,conglomerate group and been one of the largest private-owned enterprises in China. The Pharmaceutical & Chemical division has 3 sub-companies with over 3,000 employees of which over 30% are technicians; This division is mainly producing APIs, Agrochemical and Dyestuffs with related intermediates as well as other special chemicals. The group also focuses on CONTRACT MANUFACTURE service under GMP and confidential agreement with our clients.
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08

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Leucovorin

About the Company : Established in the year 2004, Sakar is engaged in manufacturing of Pharmaceutical products providing Liquid Orals, Cephalosporin Tablet, Capsule, Dry Powder Syrup, Dry Powder Injec...

Established in the year 2004, Sakar is engaged in manufacturing of Pharmaceutical products providing Liquid Orals, Cephalosporin Tablet, Capsule, Dry Powder Syrup, Dry Powder Injections, Liquid Injectables (SVP) in Ampoules and Vials & Lyophilized Injections. Sakar is managed by a team of professionals with an endeavour to offer Quality Pharmaceutical & Health Care Products in various countries. The company operates as contract development and manufacturing organisation (CDMO), being the EU GMP approved CMO for leading multinational pharmaceutical companies.
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09

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LEUCOVORIN CALCIUM

About the Company : Shouyuan chemical (one of the leading chemicals supplier in China) specializes in manufacturing, supplying, and custom synsthesis latest chemicals. Our products cover all kinds of ...

Shouyuan chemical (one of the leading chemicals supplier in China) specializes in manufacturing, supplying, and custom synsthesis latest chemicals. Our products cover all kinds of range like pharmaceuticals, agrochemicals, electronic chemicals, surfactants and other specialty chemicals.
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10

American Pharma Summit
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Calcium Folinate

About the Company : Huiyu Pharma, established in Oct. 2010, is a specialized pharmaceutical company focusing on developing and manufacturing high-quality oncology products. At present, products in our...

Huiyu Pharma, established in Oct. 2010, is a specialized pharmaceutical company focusing on developing and manufacturing high-quality oncology products. At present, products in our list include the following:Azacitidine, Bendamustine HCl, Bortezomib, Camptothecin, Carboplatin, Decitabine, Docetaxel, Doxorubicin HCl, Epirubicin HCl, Gemcitabine Hydrochloride, Irinotecan Hydrochloride, Methotrexate, Oxaliplatin, Paclitaxel, Pemetrexed disodium...We welcome those traders, distributors, and wholesalers who are interested in our products.
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GROUP","supplierCountry":"SWITZERLAND","foreign_port":"ZURICH","customer":"VIATRIS","customerCountry":"INDIA","quantity":"26.22","actualQuantity":"26.22","unit":"KGS","unitRateFc":"3808","totalValueFC":"100913.1","currency":"USD","unitRateINR":"321395.2","date":"29-Apr-2024","totalValueINR":"8426982.14","totalValueInUsd":"100913.1","indian_port":"Bangalore Air","hs_no":"29362990","bill_no":"3259681","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Crystalline","supplierPort":"ZURICH","supplierAddress":"Im Laternenacker 5, 8200 Schaffhausen,SDNF Switzerland","customerAddress":"564\/A\/22, ROAD NO.92"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1714329000,"product":"LEUCOVORIN CALCIUM CRYSTALLINE (USP),CALCIUM FOLINATE HYDRATE CRYSTALLINE(PH.EUR.)BATCH#FKG117601","address":"564\/A\/22, ROAD NO.92","city":"HYDERABAD,ANDHRA PRADESH","supplier":"MERCK GROUP","supplierCountry":"SWITZERLAND","foreign_port":"ZURICH","customer":"VIATRIS","customerCountry":"INDIA","quantity":"28.46","actualQuantity":"28.46","unit":"KGS","unitRateFc":"3808","totalValueFC":"109534.2","currency":"USD","unitRateINR":"321395.2","date":"29-Apr-2024","totalValueINR":"9146907.39","totalValueInUsd":"109534.2","indian_port":"Bangalore Air","hs_no":"29362990","bill_no":"3259681","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Crystalline","supplierPort":"ZURICH","supplierAddress":"Im Laternenacker 5, 8200 Schaffhausen,SDNF Switzerland","customerAddress":"564\/A\/22, ROAD NO.92"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1714329000,"product":"LEUCOVORIN CALCIUM CRYSTALLINE (USP),CALCIUM FOLINATE HYDRATE CRYSTALLINE(PH.EUR.)BATCH#FKG117801","address":"564\/A\/22, ROAD NO.92","city":"HYDERABAD,ANDHRA PRADESH","supplier":"MERCK GROUP","supplierCountry":"SWITZERLAND","foreign_port":"ZURICH","customer":"VIATRIS","customerCountry":"INDIA","quantity":"29.23","actualQuantity":"29.23","unit":"KGS","unitRateFc":"3808","totalValueFC":"112497.7","currency":"USD","unitRateINR":"321395.2","date":"29-Apr-2024","totalValueINR":"9394381.7","totalValueInUsd":"112497.7","indian_port":"Bangalore Air","hs_no":"29362990","bill_no":"3259681","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Crystalline","supplierPort":"ZURICH","supplierAddress":"Im Laternenacker 5, 8200 Schaffhausen,SDNF Switzerland","customerAddress":"564\/A\/22, ROAD NO.92"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1714329000,"product":"LEUCOVORIN CALCIUM CRYSTALLINE (USP),CALCIUM FOLINATE HYDRATE CRYSTALLINE(PH.EUR.)BATCH#FKG1183301","address":"564\/A\/22, ROAD NO.92","city":"HYDERABAD,ANDHRA PRADESH","supplier":"MERCK GROUP","supplierCountry":"SWITZERLAND","foreign_port":"ZURICH","customer":"VIATRIS","customerCountry":"INDIA","quantity":"26.76","actualQuantity":"26.76","unit":"KGS","unitRateFc":"3808","totalValueFC":"102991.4","currency":"USD","unitRateINR":"321395.2","date":"29-Apr-2024","totalValueINR":"8600535.55","totalValueInUsd":"102991.4","indian_port":"Bangalore Air","hs_no":"29362990","bill_no":"3259681","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Crystalline","supplierPort":"ZURICH","supplierAddress":"Im Laternenacker 5, 8200 Schaffhausen,SDNF Switzerland","customerAddress":"564\/A\/22, ROAD NO.92"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718217000,"product":"CALCIUM FOLINATE\/LEUCOVORIN CALCIUM IP ( LIST 04 SR NO. 21 )","address":"304,TOWN CENTRE,","city":"MUMBAI \/ MAHARASHTRA","supplier":"CERBIOS-PHARMA SA","supplierCountry":"SWITZERLAND","foreign_port":"ZURICH","customer":"NAPROD LIFE SCIENCES","customerCountry":"INDIA","quantity":"20.00","actualQuantity":"20","unit":"KGS","unitRateFc":"3000","totalValueFC":"60589.8","currency":"USD","unitRateINR":"252900","date":"13-Jun-2024","totalValueINR":"5058000","totalValueInUsd":"60589.8","indian_port":"Bombay Air","hs_no":"29362990","bill_no":"3974714","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"ZURICH","supplierAddress":"VIA FIGINO 6, 6917 BARBENGO \/LUGANOSWITZERLAND SWITZERLAND","customerAddress":"304,TOWN CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718217000,"product":"CALCIUM FOLINATE\/LEUCOVORIN CALCIUM IP ( LIST 04 SR NO. 21 )","address":"304,TOWN CENTRE,","city":"MUMBAI \/ MAHARASHTRA","supplier":"CERBIOS-PHARMA SA","supplierCountry":"SWITZERLAND","foreign_port":"ZURICH","customer":"NAPROD LIFE SCIENCES","customerCountry":"INDIA","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"3000","totalValueFC":"90884.7","currency":"USD","unitRateINR":"252900","date":"13-Jun-2024","totalValueINR":"7587000","totalValueInUsd":"90884.7","indian_port":"Bombay Air","hs_no":"29362990","bill_no":"3974714","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"ZURICH","supplierAddress":"VIA FIGINO 6, 6917 BARBENGO \/LUGANOSWITZERLAND SWITZERLAND","customerAddress":"304,TOWN CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1721413800,"product":"CALCIUM FOLINATE HYDRATE EP\/LEUCOVORIN CALCIUM USP","address":"PLOT NO. 87-96, SY.NO. 174 (P),","city":"R.R. DIST, HYDERABAD","supplier":"GMT FINE CHEMICALS SA","supplierCountry":"SWITZERLAND","foreign_port":"ZURICH","customer":"ZENARA PHARMA","customerCountry":"INDIA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"4600","totalValueFC":"13958.3","currency":"USD","unitRateINR":"388930","date":"20-Jul-2024","totalValueINR":"1166790","totalValueInUsd":"13958.3","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"4608561","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"ZURICH","supplierAddress":"RUE DES LLES 62108 COUVETSDNF CH","customerAddress":"PLOT NO. 87-96, SY.NO. 174 (P),"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724437800,"product":"CALCIUM FOLINATE PH EUR","address":"NO.18,DR NAIR ROAD, T NAGAR,","city":"CHENNAI","supplier":"BIOFER","supplierCountry":"ITALY","foreign_port":"BOLOGNA","customer":"STERIL-GENE LIFE SCIENCES (P) LTD","customerCountry":"INDIA","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"2200","totalValueFC":"36923","currency":"EUR","unitRateINR":"206470","date":"24-Aug-2024","totalValueINR":"3097050","totalValueInUsd":"36923","indian_port":"Madras Air","hs_no":"29420090","bill_no":"5226759","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"BOLOGNA","supplierAddress":"VIA TOMMASO DACAZZANIGA 9\/6 20121MILANO (MI) ITALY","customerAddress":"NO.18,DR NAIR ROAD, T NAGAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724956200,"product":"CALCIUM FOLINATE\/LEUCOVORIN CALCIUM IP ( LIST 04 SR NO. 21 )","address":"304,TOWN CENTRE,","city":"MUMBAI \/ MAHARASHTRA","supplier":"CERBIOS-PHARMA SA","supplierCountry":"SWITZERLAND","foreign_port":"ZURICH","customer":"NAPROD LIFE SCIENCES","customerCountry":"INDIA","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"3000","totalValueFC":"91042.4","currency":"USD","unitRateINR":"254550","date":"30-Aug-2024","totalValueINR":"7636500","totalValueInUsd":"91042.4","indian_port":"Bombay Air","hs_no":"29362990","bill_no":"5329140","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"ZURICH","supplierAddress":"VIA FIGINO 6, 6917 BARBENGO \/LUGANOSWITZERLAND SWITZERLAND","customerAddress":"304,TOWN CENTRE,"}]
20-Jan-2021
30-Oct-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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INTERMEDIATES SUPPLIERS

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01

Fermion Oy

Finland
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothWith Fermion, start the journey of your innovative API.

CAS Number : 804563-04-0

End Use API : Calcium Folinate

About The Company : Fermion is fully owned subsidiary of Orion Corporation & headquartered in Espoo, Finland. Together with Orion we are a fully integrated CDMO & offer services co...

fermion
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FDF Dossiers

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

LEUCOVORIN CALCIUM

Brand Name :

Dosage Form : Tablet

Dosage Strength : 5MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Biophore

02

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothAthena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

Flag France
Digital Content Digital Content

Regulatory Info :

Registration Country : France

Leucovorin

Brand Name :

Dosage Form : Tablet

Dosage Strength : 5MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : France

Athena Company Banner

03

Ethypharm

France
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothEthypharm is an international Pharma company with European roots manufacturing and commercializing essential drugs all over the world.

Flag France
Digital Content Digital Content

Regulatory Info :

Registration Country : France

Calcium Folinate

Brand Name :

Dosage Form : Vial

Dosage Strength : 50MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : France

Ethypharm

04

Ethypharm

France
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothEthypharm is an international Pharma company with European roots manufacturing and commercializing essential drugs all over the world.

Flag France
Digital Content Digital Content

Regulatory Info :

Registration Country : France

Calcium Folinate

Brand Name :

Dosage Form : Vial

Dosage Strength : 350MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : France

Ethypharm

05

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Calcium Folinate

Brand Name :

Dosage Form : Injection

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya

06

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Calcium Folinate

Brand Name :

Dosage Form : Injection

Dosage Strength : 200MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya

07

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Calcium Folinate

Brand Name :

Dosage Form : Injection

Dosage Strength : 350MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya

08

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Calcium Leucovorin

Brand Name :

Dosage Form : Injection

Dosage Strength : 50MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya

09

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Calcium Leucovorin

Brand Name :

Dosage Form : Injection

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya

10

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Calcium Leucovorin

Brand Name :

Dosage Form : Injection

Dosage Strength : 200MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya
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FDA Orange Book

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01

euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

LEUCOVORIN CALCIUM

Brand Name : LEUCOVORIN CALCIUM PRESERVATIVE FREE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : EQ 500MG BASE/VIAL

Approval Date : 1999-02-26

Application Number : 40286

RX/OTC/DISCN : RX

RLD : No

TE Code : AP

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02

HIKMA

United Kingdom
euroPLX 86 Munich
Not Confirmed
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HIKMA

United Kingdom
arrow
euroPLX 86 Munich
Not Confirmed

LEUCOVORIN CALCIUM

Brand Name : LEUCOVORIN CALCIUM

Dosage Form : TABLET;ORAL

Dosage Strength : EQ 5MG BASE

Approval Date : 1993-02-22

Application Number : 72733

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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03

HIKMA

United Kingdom
euroPLX 86 Munich
Not Confirmed
arrow

HIKMA

United Kingdom
arrow
euroPLX 86 Munich
Not Confirmed

LEUCOVORIN CALCIUM

Brand Name : LEUCOVORIN CALCIUM

Dosage Form : TABLET;ORAL

Dosage Strength : EQ 10MG BASE

Approval Date : 1993-02-22

Application Number : 72734

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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04

HOSPIRA

U.S.A
euroPLX 86 Munich
Not Confirmed
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HOSPIRA

U.S.A
arrow
euroPLX 86 Munich
Not Confirmed

LEUCOVORIN CALCIUM

Brand Name : LEUCOVORIN CALCIUM

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : EQ 350MG BASE/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

Approval Date : 1989-04-05

Application Number : 8107

RX/OTC/DISCN : DISCN

RLD : Yes

TE Code :

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05

LEADING

U.S.A
euroPLX 86 Munich
Not Confirmed
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LEADING

U.S.A
arrow
euroPLX 86 Munich
Not Confirmed

LEUCOVORIN CALCIUM

Brand Name : LEUCOVORIN CALCIUM

Dosage Form : TABLET;ORAL

Dosage Strength : EQ 15MG BASE

Approval Date : 2020-10-22

Application Number : 213929

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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06

PHARMACHEMIE USA

Netherlands
euroPLX 86 Munich
Not Confirmed
arrow

PHARMACHEMIE USA

Netherlands
arrow
euroPLX 86 Munich
Not Confirmed

LEUCOVORIN CALCIUM

Brand Name : LEUCOVORIN CALCIUM

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : EQ 50MG BASE/VIAL

Approval Date : 1997-04-17

Application Number : 89628

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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07

QUAD PHARMS

South Africa
euroPLX 86 Munich
Not Confirmed
arrow

QUAD PHARMS

South Africa
arrow
euroPLX 86 Munich
Not Confirmed

LEUCOVORIN CALCIUM

Brand Name : LEUCOVORIN CALCIUM

Dosage Form : Injectable; Injection

Dosage Strength : EQ 5MG BASE/ML

Approval Date :

Application Number : 89504

RX/OTC/DISCN :

RLD :

TE Code :

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08

euroPLX 86 Munich
Not Confirmed
arrow
arrow
euroPLX 86 Munich
Not Confirmed

LEUCOVORIN CALCIUM

Brand Name : LEUCOVORIN CALCIUM PRESERVATIVE FREE

Dosage Form : SOLUTION;INTRAMUSCULAR, INTRAVENOUS

Dosage Strength : EQ 500MG BASE/50ML (EQ 10MG BASE/ML)

Approval Date : 1999-06-28

Application Number : 40332

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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09

euroPLX 86 Munich
Not Confirmed
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arrow
euroPLX 86 Munich
Not Confirmed

LEUCOVORIN CALCIUM

Brand Name : LEUCOVORIN CALCIUM PRESERVATIVE FREE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : EQ 100MG BASE/VIAL

Approval Date : 2017-05-19

Application Number : 203800

RX/OTC/DISCN : RX

RLD : No

TE Code : AP

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10

euroPLX 86 Munich
Not Confirmed
arrow
arrow
euroPLX 86 Munich
Not Confirmed

LEUCOVORIN CALCIUM

Brand Name : LEUCOVORIN CALCIUM PRESERVATIVE FREE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : EQ 200MG BASE/VIAL

Approval Date : 2017-05-19

Application Number : 203800

RX/OTC/DISCN : RX

RLD : No

TE Code : AP

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