Find Levobunolol HCl manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Akbeta, Betagan, Levobunolol hcl, 27912-14-7, Levobunolol (hydrochloride), Levobunolol.hcl
Molecular Formula
C17H26ClNO3
Molecular Weight
327.8  g/mol
InChI Key
DNTDOBSIBZKFCP-YDALLXLXSA-N
FDA UNII
O90S49LDHH

Levobunolol HCl
The L-Isomer of bunolol.
1 2D Structure

Levobunolol HCl

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one;hydrochloride
2.1.2 InChI
InChI=1S/C17H25NO3.ClH/c1-17(2,3)18-10-12(19)11-21-16-9-5-6-13-14(16)7-4-8-15(13)20;/h5-6,9,12,18-19H,4,7-8,10-11H2,1-3H3;1H/t12-;/m0./s1
2.1.3 InChI Key
DNTDOBSIBZKFCP-YDALLXLXSA-N
2.1.4 Canonical SMILES
CC(C)(C)NCC(COC1=CC=CC2=C1CCCC2=O)O.Cl
2.1.5 Isomeric SMILES
CC(C)(C)NC[C@@H](COC1=CC=CC2=C1CCCC2=O)O.Cl
2.2 Other Identifiers
2.2.1 UNII
O90S49LDHH
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Akbeta

2. Apo Levobunolol

3. Apo-levobunolol

4. Apolevobunolol

5. Betagan

6. Levobunolol

7. Novo Levobunolol

8. Novo-levobunolol

9. Novolevobunolol

10. Pms Levobunolol

11. Pms-levobunolol

12. Pmslevobunolol

13. Ratio Levobunolol

14. Ratio-levobunolol

15. Ultracortenol

16. Vistagan

17. W 7000a

18. W-7000a

19. W7000a

2.3.2 Depositor-Supplied Synonyms

1. Akbeta

2. Betagan

3. Levobunolol Hcl

4. 27912-14-7

5. Levobunolol (hydrochloride)

6. Levobunolol.hcl

7. Vistagan

8. W 7000a

9. (-) -levobunolol Hydrochloride

10. L-bunolol Hydrochloride

11. Chebi:6439

12. Nsc-759158

13. W-7000a

14. Dsstox_cid_777

15. Dsstox_rid_75784

16. Dsstox_gsid_20777

17. (-)-3,4-dihydro-5-(3-(tert-butylamino)-2-hydroxypropoxy)-1(2h)-naphthalenone Hydrochloride

18. (-)-5-(3-(tert-butylamino)-2-hydroxypropoxy)-3,4-dihydro-1(2h)-naphthalenone Hydrochloride

19. O90s49ldhh

20. Levobunolol Hydrochloride [usan]

21. Ncgc00016801-01

22. Levobunolol, Hydrochloride

23. Cas-27912-14-7

24. Ent-levobunolol,hydrochloride

25. Prestwick_167

26. Betagan (tn)

27. Levobunolol Monohydrochloride

28. Schembl42262

29. Mls002154030

30. Chembl1201177

31. Dtxsid6020777

32. Hms1570j15

33. 5-[(2s)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2h-naphthalen-1-one;hydrochloride

34. Hy-b1035

35. Tox21_110617

36. Levobunolol Hydrochloride (jan/usp)

37. Levobunolol Hydrochloride [mi]

38. Tox21_110617_1

39. Ccg-220847

40. Cs-4554

41. Levobunolol Hydrochloride [jan]

42. Levobunolol Hydrochloride [mart.]

43. Levobunolol Hydrochloride [vandf]

44. Ncgc00016801-05

45. 5-({(2s)-3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl}oxy)-3,4-dihydronaphthalen-1(2h)-one Hydrochloride

46. Levobunolol Hydrochloride [usp-rs]

47. Levobunolol Hydrochloride [who-dd]

48. Smr001233357

49. D01025

50. Levobunolol Hydrochloride [orange Book]

51. Levobunolol Hydrochloride [usp Monograph]

52. Q27107207

53. (-)-(s)-5-(3-(tert-butylamino)-2-hydroxypropoxy)-3,4-dihydro-1(2h)-naphthalenone Hydrochloride

54. (2s)-n-(tert-butyl)-2-hydroxy-3-[(5-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]propan-1-aminium Chloride

55. 1(2h)-naphthalenone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-, Hydrochloride, (-)-(s)

56. 5-[(2s)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2h)-one Hydrochloride

2.4 Create Date
2005-11-20
3 Chemical and Physical Properties
Molecular Weight 327.8 g/mol
Molecular Formula C17H26ClNO3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass327.1601214 g/mol
Monoisotopic Mass327.1601214 g/mol
Topological Polar Surface Area58.6 Ų
Heavy Atom Count22
Formal Charge0
Complexity350
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameAkbeta
Active IngredientLevobunolol hydrochloride
Dosage FormSolution/drops
RouteOphthalmic
Strength0.5%; 0.25%
Market StatusPrescription
CompanyAkorn

2 of 6  
Drug NameBetagan
Drug LabelBETAGAN (levobunolol hydrochloride ophthalmic solution, USP) sterile is a noncardioselective beta-adrenoceptor blocking agent for ophthalmic use. The solution is colorless to slightly light yellow in appearance with an osmolality range of 250-360 m...
Active IngredientLevobunolol hydrochloride
Dosage FormSolution/drops
RouteOphthalmic
Strength0.5%; 0.25%
Market StatusPrescription
CompanyAllergan

3 of 6  
Drug NameLevobunolol hydrochloride
PubMed HealthLevobunolol (Into the eye)
Drug ClassesAntiglaucoma
Drug LabelBETAGAN (levobunolol hydrochloride ophthalmic solution, USP) sterile is a noncardioselective beta-adrenoceptor blocking agent for ophthalmic use. The solution is colorless to slightly light yellow in appearance with an osmolality range of 250-360 m...
Active IngredientLevobunolol hydrochloride
Dosage FormSolution/drops
RouteOphthalmic
Strength0.5%; 0.25%
Market StatusPrescription
CompanyFalcon Pharms; Bausch And Lomb

4 of 6  
Drug NameAkbeta
Active IngredientLevobunolol hydrochloride
Dosage FormSolution/drops
RouteOphthalmic
Strength0.5%; 0.25%
Market StatusPrescription
CompanyAkorn

5 of 6  
Drug NameBetagan
Drug LabelBETAGAN (levobunolol hydrochloride ophthalmic solution, USP) sterile is a noncardioselective beta-adrenoceptor blocking agent for ophthalmic use. The solution is colorless to slightly light yellow in appearance with an osmolality range of 250-360 m...
Active IngredientLevobunolol hydrochloride
Dosage FormSolution/drops
RouteOphthalmic
Strength0.5%; 0.25%
Market StatusPrescription
CompanyAllergan

6 of 6  
Drug NameLevobunolol hydrochloride
PubMed HealthLevobunolol (Into the eye)
Drug ClassesAntiglaucoma
Drug LabelBETAGAN (levobunolol hydrochloride ophthalmic solution, USP) sterile is a noncardioselective beta-adrenoceptor blocking agent for ophthalmic use. The solution is colorless to slightly light yellow in appearance with an osmolality range of 250-360 m...
Active IngredientLevobunolol hydrochloride
Dosage FormSolution/drops
RouteOphthalmic
Strength0.5%; 0.25%
Market StatusPrescription
CompanyFalcon Pharms; Bausch And Lomb

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Sympatholytics

Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here. (See all compounds classified as Sympatholytics.)


Adrenergic beta-Antagonists

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. (See all compounds classified as Adrenergic beta-Antagonists.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
beta-Adrenergic Blocker [EPC]; Adrenergic beta-Antagonists [MoA]

Global Sales Information

Do you need Business Intel? Ask us

Market Place

Do you need sourcing support? Ask us

ABOUT THIS PAGE

Levobunolol HCl Manufacturers

A Levobunolol HCl manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Levobunolol HCl, including repackagers and relabelers. The FDA regulates Levobunolol HCl manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Levobunolol HCl API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Levobunolol HCl Suppliers

A Levobunolol HCl supplier is an individual or a company that provides Levobunolol HCl active pharmaceutical ingredient (API) or Levobunolol HCl finished formulations upon request. The Levobunolol HCl suppliers may include Levobunolol HCl API manufacturers, exporters, distributors and traders.

Levobunolol HCl GMP

Levobunolol HCl Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Levobunolol HCl GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Levobunolol HCl GMP manufacturer or Levobunolol HCl GMP API supplier for your needs.

Levobunolol HCl CoA

A Levobunolol HCl CoA (Certificate of Analysis) is a formal document that attests to Levobunolol HCl's compliance with Levobunolol HCl specifications and serves as a tool for batch-level quality control.

Levobunolol HCl CoA mostly includes findings from lab analyses of a specific batch. For each Levobunolol HCl CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Levobunolol HCl may be tested according to a variety of international standards, such as European Pharmacopoeia (Levobunolol HCl EP), Levobunolol HCl JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Levobunolol HCl USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty