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Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

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CEP/COS

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JDMF

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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$ 0

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FDF

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Europe

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Canada

Canada

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Australia

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South Africa

South Africa

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FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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USP

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Chemistry

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Also known as:
Molecular Formula
C20H25N7O6
Molecular Weight
459.5  g/mol
InChI Key
ZNOVTXRBGFNYRX-STQMWFEESA-N

Levomefolate
1 2D Structure

Levomefolate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
2.1.2 InChI
InChI=1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31)/t12-,13-/m0/s1
2.1.3 InChI Key
ZNOVTXRBGFNYRX-STQMWFEESA-N
2.1.4 Canonical SMILES
CN1C(CNC2=C1C(=O)N=C(N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
2.1.5 Isomeric SMILES
CN1[C@H](CNC2=C1C(=O)N=C(N2)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
2.2 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 459.5 g/mol
Molecular Formula C20H25N7O6
XLogP3-0.5
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count9
Rotatable Bond Count9
Exact Mass459.18663154 g/mol
Monoisotopic Mass459.18663154 g/mol
Topological Polar Surface Area199 A^2
Heavy Atom Count33
Formal Charge0
Complexity865
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

Listed Suppliers

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01

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

Levomefolate

About the Company : Anthem Biosciences is a leading contract research and innovation service provider (CRISP) in Bengaluru, India, which manufactures novel drug actives. Established in 2007, it specia...

Anthem Biosciences is a leading contract research and innovation service provider (CRISP) in Bengaluru, India, which manufactures novel drug actives. Established in 2007, it specializes in both biological and chemistry-based products and services. It has a strong track record in drug and product development, and supports development, optimization and testing of various compounds including proteins, monoclonal antibodies, peptides, large & small molecules and toxins. Inspected by USFDA, Japan’s PMDA, EU QPs, it develops nutritional products using organic synthesis and offers quality control and regulatory compliance assistance to clients.
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02

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

L-methylfolate

About the Company : The company is in the business of manufacturing and marketing botanical extracts and nutraceuticals formulations to both domestic and global customers. The products include health/...

The company is in the business of manufacturing and marketing botanical extracts and nutraceuticals formulations to both domestic and global customers. The products include health/dietary supplements for improving the overall wellness/prevention of diseases, ingredients for functional foods, food colors, and extracts. The company exports to around 35 countries in Europe, US, and Japan, with strong relations with global majors. The company has production facilities near Bengaluru (Peenya, Tumkur, Bidadi), Bhatkal, Hyderabad and Pune.
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03

Cerbios-Pharma SA

Switzerland
AES 2024
Not Confirmed
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Cerbios-Pharma SA

Switzerland
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AES 2024
Not Confirmed

Levomefolate

About the Company : Cerbios is a privately held company located in Lugano, Switzerland. Cerbios is the ideal CDMO partner from clinical to commercial supply of ADCs, HPAPIs, Proteins and Antibodies. ...

Cerbios is a privately held company located in Lugano, Switzerland. Cerbios is the ideal CDMO partner from clinical to commercial supply of ADCs, HPAPIs, Proteins and Antibodies. Services offered include Process & Analytical Development, Scale-up and Clinical Supply, Industrial Validation, Commercial Supply and Full CMC Regulatory Support. Cerbios supplies also generic APIs primarily used in Oncology, Respiratory and Dermatology. Cerbios has additionally a 40 years’ experience in the probiotics field: the portfolio includes a FDF based on proprietary strain SF68® for treatment of diarrhea & dysbiosis, ACNE & Seborrheic dermatitis.
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