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CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

14 API Suppliers, 1 USDMF, 5 CEP/COS, 3 JDMF, 1 EU WC, 8 Listed Suppliers

14 API Suppliers
1 USDMF
5 CEP/COS
3 JDMF
1 EU WC
8 Listed Suppliers

DEVELOPMENTS

2 Drugs in Development

2 Drugs in Development

INTERMEDIATES

8 Intermediates Suppliers

8 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

35 FDF Dossiers, 1 FDA Orange Book, 15 Europe, 10 Canada, 9 Listed Dossiers

35 FDF Dossiers
1 FDA Orange Book
15 Europe
10 Canada
9 Listed Dossiers

DIGITAL CONTENT

2 NEWS #PharmaBuzz

media
2 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

10 Finished Drug Prices

globalSalesInformation
10 Finished Drug Prices

MARKET PLACE

6 APIs, 4 FDF Dossiers

marketPlace
6 APIs
4 FDF Dossiers

REF. STANDARDS & IMPURITIES

2 EDQM , 1 USP

otherSolutions
2 EDQM
1 USP

Egis Levomepromazine Maleate

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 407

MARKET PLACE

API

FDF

8INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

2DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 7104-38-3, Methotrimeprazine maleate, Levo mepromazine maleate, Milezin, Minozinan, Neuractil

Molecular Formula

C₂₃H₂₈N₂O₅S

Molecular Weight

444.5 g/mol

InChI Key

IFLZPECPTYCEBR-VIEYUMQNSA-N

FDA UNII

5KN5Y9V01K

1 2D Structure

Levomepromazine Maleate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(Z)-but-2-enedioic acid;(2R)-3-(2-methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine

2.1.2 InChI

InChI=1S/C19H24N2OS.C4H4O4/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21;5-3(6)1-2-4(7)8/h5-11,14H,12-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-;/m1./s1

2.1.3 InChI Key

IFLZPECPTYCEBR-VIEYUMQNSA-N

2.1.4 Canonical SMILES

CC(CN1C2=CC=CC=C2SC3=C1C=C(C=C3)OC)CN(C)C.C(=CC(=O)O)C(=O)O

2.1.5 Isomeric SMILES

C[C@@H](CN1C2=CC=CC=C2SC3=C1C=C(C=C3)OC)CN(C)C.C(=C\C(=O)O)\C(=O)O

2.2 Other Identifiers

2.2.1 UNII

5KN5Y9V01K

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 7104-38-3

2. Methotrimeprazine Maleate

3. Levo Mepromazine Maleate

4. Milezin

5. Minozinan

6. Neuractil

7. Neurocil

8. Sofmin

9. Levomepromazine Hydrogen Maleate

10. Hirnamin

11. Nozinan

12. Tisercin

13. Veractil

14. Levomepromazinum

15. 5kn5y9v01k

16. Methoprazine

17. (2r)-3-(2-methoxyphenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine Maleate

18. (z)-but-2-enedioic Acid;(2r)-3-(2-methoxyphenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine

19. Methotrimeprazine Maleat Salt

20. Unii-5kn5y9v01k

21. Levomepromazinmaleat

22. Hirnamin (tn)

23. Einecs 230-412-8

24. Levomepromazine Maleate [usan:jan]

25. Ncgc00016681-01

26. Cas-7104-38-3

27. Dsstox_cid_25399

28. Dsstox_rid_80853

29. Dsstox_gsid_45399

30. Schembl218717

31. Levomepromazinum [hpus]

32. Chembl1725730

33. Dtxsid4045399

34. Hms1570o16

35. Hms2097o16

36. Hms3714o16

37. Levomepromazine Maleate [mi]

38. Tox21_110559

39. Levomepromazine Maleate [jan]

40. Levomepromazine Maleate [usan]

41. Akos025116974

42. Levomepromazine Maleate (jp17/usan)

43. Ccg-220797

44. Levomepromazine Maleate [mart.]

45. Levomepromazine Maleate [who-dd]

46. 10h-phenothiazine-10-propanamine, 2-methoxy-n,n,.beta.-trimethyl-, (.beta.r)-, (2z)-2-butenedioate (1:1)

47. Cs-0455065

48. L0299

49. Levomepromazine Maleate [ep Monograph]

50. D02248

51. 104l383

52. Sr-01000872673

53. Sr-01000872673-1

54. Q27262488

55. Levomepromazine Maleate 1.0 Mg/ml In Methanol (as Free Base)

56. (betar)-2-methoxy-n,n,beta-trimethyl-10h-phenothiazine-10-propanamine (2z)-2-butenedioate

57. (r)-3-(2-methoxy-10h-phenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine Maleate

58. But-2-enedioic Acid;(2r)-3-(2-methoxyphenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine

59. (2r)-3-(2-methoxy-10h-phenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine (2z)-but-2-enedioate

60. (2r)-3-(2-methoxy-10h-phenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine Hydrogen (2z)-but-2-enedioate

61. 10h-phenothiazine-10-propanamine, 2-methoxy-n,n,beta-trimethyl-, (betar)-, (2z)-2-butenedioate (1:1)

2.4 Create Date

2005-10-11

3 Chemical and Physical Properties

Molecular Formula	C₂₃H₂₈N₂O₅S
Molecular Weight	444.5 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	7
Exact Mass	444.17189317 g/mol
Monoisotopic Mass	444.17189317 g/mol
Topological Polar Surface Area	116 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	497
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2