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    Chemistry

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    Also known as: 7104-38-3, Methotrimeprazine maleate, Levo mepromazine maleate, Milezin, Minozinan, Neuractil
    Molecular Formula
    C23H28N2O5S
    Molecular Weight
    444.5  g/mol
    InChI Key
    IFLZPECPTYCEBR-VIEYUMQNSA-N
    FDA UNII
    5KN5Y9V01K
    Levomepromazine Maleate
    1 2D Structure

    Levomepromazine Maleate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (Z)-but-2-enedioic acid;(2R)-3-(2-methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
    2.1.2 InChI
    InChI=1S/C19H24N2OS.C4H4O4/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21;5-3(6)1-2-4(7)8/h5-11,14H,12-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-;/m1./s1
    2.1.3 InChI Key
    IFLZPECPTYCEBR-VIEYUMQNSA-N
    2.1.4 Canonical SMILES
    CC(CN1C2=CC=CC=C2SC3=C1C=C(C=C3)OC)CN(C)C.C(=CC(=O)O)C(=O)O
    2.1.5 Isomeric SMILES
    C[C@@H](CN1C2=CC=CC=C2SC3=C1C=C(C=C3)OC)CN(C)C.C(=C\C(=O)O)\C(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    5KN5Y9V01K
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 7104-38-3

    2. Methotrimeprazine Maleate

    3. Levo Mepromazine Maleate

    4. Milezin

    5. Minozinan

    6. Neuractil

    7. Neurocil

    8. Sofmin

    9. Levomepromazine Hydrogen Maleate

    10. Hirnamin

    11. Nozinan

    12. Tisercin

    13. Veractil

    14. Levomepromazinum

    15. 5kn5y9v01k

    16. Methoprazine

    17. (2r)-3-(2-methoxyphenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine Maleate

    18. (z)-but-2-enedioic Acid;(2r)-3-(2-methoxyphenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine

    19. Methotrimeprazine Maleat Salt

    20. Unii-5kn5y9v01k

    21. Levomepromazinmaleat

    22. Hirnamin (tn)

    23. Einecs 230-412-8

    24. Levomepromazine Maleate [usan:jan]

    25. Ncgc00016681-01

    26. Cas-7104-38-3

    27. Dsstox_cid_25399

    28. Dsstox_rid_80853

    29. Dsstox_gsid_45399

    30. Schembl218717

    31. Levomepromazinum [hpus]

    32. Chembl1725730

    33. Dtxsid4045399

    34. Hms1570o16

    35. Hms2097o16

    36. Hms3714o16

    37. Levomepromazine Maleate [mi]

    38. Tox21_110559

    39. Levomepromazine Maleate [jan]

    40. Levomepromazine Maleate [usan]

    41. Akos025116974

    42. Levomepromazine Maleate (jp17/usan)

    43. Ccg-220797

    44. Levomepromazine Maleate [mart.]

    45. Levomepromazine Maleate [who-dd]

    46. 10h-phenothiazine-10-propanamine, 2-methoxy-n,n,.beta.-trimethyl-, (.beta.r)-, (2z)-2-butenedioate (1:1)

    47. Cs-0455065

    48. L0299

    49. Levomepromazine Maleate [ep Monograph]

    50. D02248

    51. 104l383

    52. Sr-01000872673

    53. Sr-01000872673-1

    54. Q27262488

    55. Levomepromazine Maleate 1.0 Mg/ml In Methanol (as Free Base)

    56. (betar)-2-methoxy-n,n,beta-trimethyl-10h-phenothiazine-10-propanamine (2z)-2-butenedioate

    57. (r)-3-(2-methoxy-10h-phenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine Maleate

    58. But-2-enedioic Acid;(2r)-3-(2-methoxyphenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine

    59. (2r)-3-(2-methoxy-10h-phenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine (2z)-but-2-enedioate

    60. (2r)-3-(2-methoxy-10h-phenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine Hydrogen (2z)-but-2-enedioate

    61. 10h-phenothiazine-10-propanamine, 2-methoxy-n,n,beta-trimethyl-, (betar)-, (2z)-2-butenedioate (1:1)

    2.4 Create Date
    2005-10-11
    3 Chemical and Physical Properties
    Molecular Weight 444.5 g/mol
    Molecular Formula C23H28N2O5S
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count7
    Exact Mass444.17189317 g/mol
    Monoisotopic Mass444.17189317 g/mol
    Topological Polar Surface Area116 Ų
    Heavy Atom Count31
    Formal Charge0
    Complexity497
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count1
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2

    API Reference Price

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    31-Mar-2021
    27-Nov-2024
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    ABOUT THIS PAGE

    Levomepromazine Maleate Manufacturers

    A Levomepromazine Maleate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Levomepromazine Maleate, including repackagers and relabelers. The FDA regulates Levomepromazine Maleate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Levomepromazine Maleate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Levomepromazine Maleate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Levomepromazine Maleate Suppliers

    A Levomepromazine Maleate supplier is an individual or a company that provides Levomepromazine Maleate active pharmaceutical ingredient (API) or Levomepromazine Maleate finished formulations upon request. The Levomepromazine Maleate suppliers may include Levomepromazine Maleate API manufacturers, exporters, distributors and traders.

    click here to find a list of Levomepromazine Maleate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Levomepromazine Maleate USDMF

    A Levomepromazine Maleate DMF (Drug Master File) is a document detailing the whole manufacturing process of Levomepromazine Maleate active pharmaceutical ingredient (API) in detail. Different forms of Levomepromazine Maleate DMFs exist exist since differing nations have different regulations, such as Levomepromazine Maleate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Levomepromazine Maleate DMF submitted to regulatory agencies in the US is known as a USDMF. Levomepromazine Maleate USDMF includes data on Levomepromazine Maleate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Levomepromazine Maleate USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Levomepromazine Maleate suppliers with USDMF on PharmaCompass.

    Levomepromazine Maleate JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Levomepromazine Maleate Drug Master File in Japan (Levomepromazine Maleate JDMF) empowers Levomepromazine Maleate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Levomepromazine Maleate JDMF during the approval evaluation for pharmaceutical products. At the time of Levomepromazine Maleate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Levomepromazine Maleate suppliers with JDMF on PharmaCompass.

    Levomepromazine Maleate CEP

    A Levomepromazine Maleate CEP of the European Pharmacopoeia monograph is often referred to as a Levomepromazine Maleate Certificate of Suitability (COS). The purpose of a Levomepromazine Maleate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Levomepromazine Maleate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Levomepromazine Maleate to their clients by showing that a Levomepromazine Maleate CEP has been issued for it. The manufacturer submits a Levomepromazine Maleate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Levomepromazine Maleate CEP holder for the record. Additionally, the data presented in the Levomepromazine Maleate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Levomepromazine Maleate DMF.

    A Levomepromazine Maleate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Levomepromazine Maleate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Levomepromazine Maleate suppliers with CEP (COS) on PharmaCompass.

    Levomepromazine Maleate WC

    A Levomepromazine Maleate written confirmation (Levomepromazine Maleate WC) is an official document issued by a regulatory agency to a Levomepromazine Maleate manufacturer, verifying that the manufacturing facility of a Levomepromazine Maleate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Levomepromazine Maleate APIs or Levomepromazine Maleate finished pharmaceutical products to another nation, regulatory agencies frequently require a Levomepromazine Maleate WC (written confirmation) as part of the regulatory process.

    click here to find a list of Levomepromazine Maleate suppliers with Written Confirmation (WC) on PharmaCompass.

    Levomepromazine Maleate GMP

    Levomepromazine Maleate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Levomepromazine Maleate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Levomepromazine Maleate GMP manufacturer or Levomepromazine Maleate GMP API supplier for your needs.

    Levomepromazine Maleate CoA

    A Levomepromazine Maleate CoA (Certificate of Analysis) is a formal document that attests to Levomepromazine Maleate's compliance with Levomepromazine Maleate specifications and serves as a tool for batch-level quality control.

    Levomepromazine Maleate CoA mostly includes findings from lab analyses of a specific batch. For each Levomepromazine Maleate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Levomepromazine Maleate may be tested according to a variety of international standards, such as European Pharmacopoeia (Levomepromazine Maleate EP), Levomepromazine Maleate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Levomepromazine Maleate USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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