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    Chemistry

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    Also known as: Levorphanol tartrate anhydrous, Levorphan tartrate, Levorphanol bitartrate, Wcb1i20f1k, 125-72-4, D-(-)-levorphanol tartrate
    Molecular Formula
    C21H29NO7
    Molecular Weight
    407.5  g/mol
    InChI Key
    RWTWIZDKEIWLKQ-IWWMGODWSA-N
    FDA UNII
    WCB1I20F1K
    Levorphanol Tartrate
    1 2D Structure

    Levorphanol Tartrate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (2R,3R)-2,3-dihydroxybutanedioic acid;(1R,9R,10R)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol
    2.1.2 InChI
    InChI=1S/C17H23NO.C4H6O6/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17;5-1(3(7)8)2(6)4(9)10/h5-6,11,14,16,19H,2-4,7-10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t14-,16+,17+;1-,2-/m01/s1
    2.1.3 InChI Key
    RWTWIZDKEIWLKQ-IWWMGODWSA-N
    2.1.4 Canonical SMILES
    CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)O.C(C(C(=O)O)O)(C(=O)O)O
    2.1.5 Isomeric SMILES
    CN1CC[C@]23CCCC[C@H]2[C@H]1CC4=C3C=C(C=C4)O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
    2.2 Other Identifiers
    2.2.1 UNII
    WCB1I20F1K
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. Levorphanol Tartrate Anhydrous

    2. Levorphan Tartrate

    3. Levorphanol Bitartrate

    4. Wcb1i20f1k

    5. 125-72-4

    6. D-(-)-levorphanol Tartrate

    7. Morphinan-3-ol, 17-methyl-, (r-(r*,r*))-2,3-dihydroxybutanedioate (1:1) (salt)

    8. L-3-hydroxy-n-methylmorphinan Tartrate

    9. Ro 1-5431/7

    10. Levorphanol Hydrogen Tartrate

    11. Nih 4590

    12. Einecs 204-753-8

    13. Nsc 91012

    14. Unii-wcb1i20f1k

    15. Nsc-91012

    16. Levorphanol L-tartrate

    17. Morphinan-3-ol, 17-methyl-, Tartrate (1:1) (salt), (-)-

    18. Morphinan-6-ol, N-methyl-, Tartrate (1:1) (salt), Stereoisomer

    19. 2h-10,4a-iminoethanophenanthren-6-ol, 1,3,4,9,10,10a-hexahydro-11-methyl-, Tartrate

    20. Schembl4336924

    21. Dtxsid30924987

    22. Pdsp2_001546

    23. Levorphanol Tartrate [who-dd]

    24. Morphinan-3-ol, 17-methyl-, (2r,3r)-2,3-dihydroxybutanedioate (1:1)

    25. Q27292556

    26. 17-methylmorphinan-3-ol, Tartrate (1:1) (salt)

    27. 17-methylmorphinan-3-ol (2r,3r)-2,3-dihydroxybutanedioate (1:1) (salt)

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 407.5 g/mol
    Molecular Formula C21H29NO7
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count3
    Exact Mass407.19440226 g/mol
    Monoisotopic Mass407.19440226 g/mol
    Topological Polar Surface Area139 Ų
    Heavy Atom Count29
    Formal Charge0
    Complexity491
    Isotope Atom Count0
    Defined Atom Stereocenter Count5
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameLevorphanol tartrate
    Drug LabelLevo-Dromoran (levorphanol tartrate) is a potent opioid analgesic with empirical formula C17H23NOC4H6O62H2O and molecular weight 443.5. Each mg of levorphanol tartrate is equivalent to 0.58 mg levorphanol base. Chemically levorphanol is levo-3-...
    Active IngredientLevorphanol tartrate
    Dosage FormTablet
    RouteOral
    Strength2mg
    Market StatusPrescription
    CompanyRoxane

    2 of 2  
    Drug NameLevorphanol tartrate
    Drug LabelLevo-Dromoran (levorphanol tartrate) is a potent opioid analgesic with empirical formula C17H23NOC4H6O62H2O and molecular weight 443.5. Each mg of levorphanol tartrate is equivalent to 0.58 mg levorphanol base. Chemically levorphanol is levo-3-...
    Active IngredientLevorphanol tartrate
    Dosage FormTablet
    RouteOral
    Strength2mg
    Market StatusPrescription
    CompanyRoxane

    API SUPPLIERS

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    Nuray Chemicals Private Limited

    India

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    DMF Review : Reviewed

    Rev. Date : 2019-03-07

    Pay. Date : 2019-01-28

    DMF Number : 33224

    Submission : 2018-12-31

    Status : Active

    Type : II

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    NDC Package Code : 58159-061

    Start Marketing Date : 2019-11-15

    End Marketing Date : 2024-12-31

    Dosage Form (Strength) : POWDER (35kg/35kg)

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    HRV Global Life Sciences

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    Noramco

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    DMF Review : Reviewed

    Rev. Date : 2021-08-16

    Pay. Date : 2021-06-10

    DMF Number : 35977

    Submission : 2021-05-31

    Status : Active

    Type : II

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    American Pacific Corporation

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    DMF Review : Reviewed

    Rev. Date : 2023-05-17

    Pay. Date : 2023-04-03

    DMF Number : 34304

    Submission : 2020-01-17

    Status : Active

    Type : II

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    NDC Package Code : 50683-0514

    Start Marketing Date : 2019-12-06

    End Marketing Date : 2024-12-31

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    Mallinckrodt Pharmaceuticals

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    Mallinckrodt Pharmaceuticals

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    DMF Review : Reviewed

    Rev. Date : 2017-11-21

    Pay. Date : 2017-09-08

    DMF Number : 18823

    Submission : 2005-09-29

    Status : Active

    Type : II

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    NDC Package Code : 0406-0545

    Start Marketing Date : 2013-04-01

    End Marketing Date : 2025-12-31

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    Mallinckrodt Pharmaceuticals

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    DMF Review : N/A

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    DMF Number : 20747

    Submission : 2007-08-02

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    NDC Package Code : 0406-0545

    Start Marketing Date : 2013-04-01

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    Mallinckrodt Pharmaceuticals

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    GDUFA

    DMF Review : N/A

    Rev. Date :

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    DMF Number : 7625

    Submission : 1988-08-09

    Status : Inactive

    Type : II

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    NDC Package Code : 0406-0545

    Start Marketing Date : 2013-04-01

    End Marketing Date : 2025-12-31

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    Mallinckrodt Pharmaceuticals

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    DMF Review : N/A

    Rev. Date :

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    DMF Number : 9968

    Submission : 1992-11-13

    Status : Inactive

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    NDC Package Code : 0406-0545

    Start Marketing Date : 2013-04-01

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    F. Hoffmann-La Roche

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    F. Hoffmann-La Roche

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    DMF Review : N/A

    Rev. Date :

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    DMF Number : 3726

    Submission : 1980-02-15

    Status : Inactive

    Type : II

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    API Reference Price

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    [{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1680719400,"product":"LEVORPHANOL TARTRATE USP","address":"25, 12TH CROSS STREET, SHASTRI NAGAR,","city":"CHENNAI\/TAMILNADU","supplier":"NURAY CHEMICALS PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"NEW YORK","customer":"THE PURCHASE MANAGER","customerCountry":"UNITED STATES","quantity":"1.10","actualQuantity":"1.1","unit":"KGS","unitRateFc":"250000","totalValueFC":"274813.4","currency":"USD","unitRateINR":20474545.454545453,"date":"06-Apr-2023","totalValueINR":"22522000","totalValueInUsd":"274813.4","indian_port":"MADRAS AIR","hs_no":"29334100","bill_no":"9112748","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRAS AIR","supplierAddress":"25, 12TH CROSS STREET, SHASTRI NAGAR,, CHENNAI\/TAMILNADU","customerAddress":""}]
    06-Apr-2023
    06-Apr-2023
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