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Chemistry

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Also known as: 66871-56-5, Lidamidine [inn], N-(2,6-dimethylphenyl)-n'-(imino(methylamino)methyl)urea, 1-(2,6-dimethylphenyl)-3-(n'-methylcarbamimidoyl)urea, 2-[({[imino(methylamino)methyl]amino}carbonyl)amino]-1,3-dimethylbenzene, Lidamidine (inn)
Molecular Formula
C11H16N4O
Molecular Weight
220.27  g/mol
InChI Key
RRHJHSBDJDZUGL-UHFFFAOYSA-N
FDA UNII
Q8X04W8418

Lidamidine
1 2D Structure

Lidamidine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-(2,6-dimethylphenyl)-3-(N'-methylcarbamimidoyl)urea
2.1.2 InChI
InChI=1S/C11H16N4O/c1-7-5-4-6-8(2)9(7)14-11(16)15-10(12)13-3/h4-6H,1-3H3,(H4,12,13,14,15,16)
2.1.3 InChI Key
RRHJHSBDJDZUGL-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C(C(=CC=C1)C)NC(=O)NC(=NC)N
2.2 Other Identifiers
2.2.1 UNII
Q8X04W8418
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1-(2,6-dimethylphenyl)-3-methylamidinourea

2. Lidamidine, Hydrochloride

3. Lidamidine, Monohydrochloride

4. Whr-1142a

2.3.2 Depositor-Supplied Synonyms

1. 66871-56-5

2. Lidamidine [inn]

3. N-(2,6-dimethylphenyl)-n'-(imino(methylamino)methyl)urea

4. 1-(2,6-dimethylphenyl)-3-(n'-methylcarbamimidoyl)urea

5. 2-[({[imino(methylamino)methyl]amino}carbonyl)amino]-1,3-dimethylbenzene

6. Lidamidine (inn)

7. 1-(2,6-dimethylphenyl)-3-(n-methylcarbamimidoyl)urea

8. Q8x04w8418

9. Ncgc00160661-01

10. Urea, N-(2,6-dimethylphenyl)-n'-(imino(methylamino)methyl)-

11. Dsstox_cid_29006

12. Dsstox_rid_83271

13. Dsstox_gsid_49080

14. Lidamidina

15. Lidamidinum

16. Urea, N-(2,6-dimethylphenyl)-n'-[imino(methylamino)methyl]-

17. Urea,n-(2,6-dimethylphenyl)-n'-[imino(methylamino)methyl]-

18. Lidamidinum [inn-latin]

19. Lidamidina [inn-spanish]

20. Cas-66871-56-5

21. Unii-q8x04w8418

22. Lidamidine [mi]

23. Timtec1_004303

24. Lidamidine [who-dd]

25. Schembl122710

26. Chembl448416

27. Dtxsid4049080

28. Chebi:134907

29. Hms1546d13

30. Tox21_113641

31. Mfcd00449519

32. Stk095480

33. Zinc13115357

34. Akos001737102

35. Tox21_113641_1

36. Ms-3109

37. Ncgc00160661-02

38. 1-(2',6'-dimethylphenyl)-3-methylamidinourea

39. 1-(methylamidino)-3-(2,6-xylyl)urea

40. D08126

41. 1-(2', 6'-dimethylphenyl)-3-methylamidinourea

42. Sr-01000308723

43. Sr-01000308723-1

44. Brd-k68693535-001-01-8

45. Q27287122

46. Urea, 1-(2,6-dimethyl)phenyl-3-(n-methylamidino)-

2.4 Create Date
2005-07-07
3 Chemical and Physical Properties
Molecular Weight 220.27 g/mol
Molecular Formula C11H16N4O
XLogP31.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass220.13241115 g/mol
Monoisotopic Mass220.13241115 g/mol
Topological Polar Surface Area79.5 Ų
Heavy Atom Count16
Formal Charge0
Complexity267
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antidiarrheals

Miscellaneous agents found useful in the symptomatic treatment of diarrhea. They have no effect on the agent(s) that cause diarrhea, but merely alleviate the condition. (See all compounds classified as Antidiarrheals.)


Adrenergic Agonists

Drugs that bind to and activate adrenergic receptors. (See all compounds classified as Adrenergic Agonists.)


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