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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

MARKET PLACE

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API

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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Europe

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Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

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DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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USP

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Chemistry

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Also known as: 1180-71-8, Dictamnolactone, Obaculactone, Citrolimonin, Evodin, Limonine
Molecular Formula
C26H30O8
Molecular Weight
470.5  g/mol
InChI Key
KBDSLGBFQAGHBE-MSGMIQHVSA-N
FDA UNII
L0F260866S

Limonin
limonin is a natural product found in Flacourtia jangomas, Raulinoa echinata, and other organisms with data available.
1 2D Structure

Limonin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1R,2R,7S,10R,13R,14R,16S,19S,20S)-19-(furan-3-yl)-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.02,7.02,10.014,16.014,20]docosane-5,12,17-trione
2.1.2 InChI
InChI=1S/C26H30O8/c1-22(2)15-9-16(27)24(4)14(25(15)12-31-18(28)10-17(25)33-22)5-7-23(3)19(13-6-8-30-11-13)32-21(29)20-26(23,24)34-20/h6,8,11,14-15,17,19-20H,5,7,9-10,12H2,1-4H3/t14-,15-,17-,19-,20+,23-,24-,25+,26+/m0/s1
2.1.3 InChI Key
KBDSLGBFQAGHBE-MSGMIQHVSA-N
2.1.4 Canonical SMILES
CC1(C2CC(=O)C3(C(C24COC(=O)CC4O1)CCC5(C36C(O6)C(=O)OC5C7=COC=C7)C)C)C
2.1.5 Isomeric SMILES
C[C@@]12CC[C@H]3[C@]([C@@]14[C@H](O4)C(=O)O[C@H]2C5=COC=C5)(C(=O)C[C@@H]6[C@@]37COC(=O)C[C@@H]7OC6(C)C)C
2.2 Other Identifiers
2.2.1 UNII
L0F260866S
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 7,16-dioxo-7,16-dideoxylimondiol

2. Obaculactone

2.3.2 Depositor-Supplied Synonyms

1. 1180-71-8

2. Dictamnolactone

3. Obaculactone

4. Citrolimonin

5. Evodin

6. Limonine

7. 7,16-dioxo-7,16-dideoxylimondiol

8. Limoni

9. Limonoic Acid, Di-delta-lactone

10. Evodia Fruit

11. Nsc 36508

12. Limonoic Acid 3,19:16,17-dilactone

13. Limonoate D-ring-lactone

14. (4as,6ar,8ar,8br,9as,12s,12as,14ar,14br)-12-(furan-3-yl)-6,6,8a,12a-tetramethyldecahydro-1h,3h-oxireno[2,3-d]pyrano[4',3':3,3a]isobenzofuro[5,4-f]isochromene-3,8,10(6h,9ah)-trione

15. Chebi:16226

16. Limonoic Acid 3,19:16,17 Dilactone

17. L0f260866s

18. Dsstox_cid_25985

19. Dsstox_rid_81273

20. Dsstox_gsid_45985

21. (4as,6ar,8ar,8br,9as,12s,12as,14ar,14br)-12-(furan-3-yl)-6,6,8a,12a-tetramethyldecahydrooxireno[2,3-d]pyrano[4',3':3,3a]isobenzofuro[5,4-f]isochromene-3,8,10(1h,6h,8ah)-trione

22. 11h,13h-oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2h,5ah)-trione, 8-(3-furyl)decahydro-2,2,4a,8a-tetramethyl-

23. Limone

24. Mfcd00075922

25. (1r,2r,7s,10r,13r,14r,16s,19s,20s)-19-(furan-3-yl)-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.02,7.02,10.014,16.014,20]docosane-5,12,17-trione

26. (4as,6ar,8ar,8br,9as,12r,12as,14ar,14br)-12-(3-furyl)-6,6,8a,12a-tetramethyldecahydro-3h-oxireno[d]pyrano[4',3':3,3a][2]benzofuro[5,4-f]isochromene-3,8,10(6h,9ah)-trione

27. 11h,13h-oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2h,5ah)-trione, 8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-, (2ar,4ar,4br,5as,8s,8as,10ar,10br,14as)-

28. 1809582-56-6

29. Rel-(4as,6ar,8ar,8br,9as,12s,12as,14ar,14br)-12-(furan-3-yl)-6,6,8a,12a-tetramethyldecahydrooxireno[2,3-d]pyrano[4',3':3,3a]isobenzofuro[5,4-f]isochromene-3,8,10(1h,6h,8ah)-trione

30. Cas-1180-71-8

31. Limonoic Acid Di-delta-lactone

32. 3-furyl(tetramethyl)[?]trione

33. Linonin

34. Nsc36508

35. Ccris 4047

36. Nsc-36508

37. Unii-l0f260866s

38. Ncgc00095714-01

39. Limonoic Acid, Di-.delta.-lactone

40. Ai3-37932

41. Limonin [mi]

42. Spectrum2_001728

43. Spectrum3_001012

44. Spectrum4_001140

45. Spectrum5_000935

46. Limonin, Analytical Standard

47. Bspbio_002763

48. Kbiogr_001659

49. Limonoic Acid Di-del.-lactone

50. Schembl320315

51. Spectrum1800018

52. Spbio_001776

53. Chembl517449

54. Dtxsid8045985

55. Acon1_001996

56. Kbio3_001983

57. Limonoic Acid Di-.delta.-lactone

58. Zinc4096134

59. Tox21_111513

60. Bdbm50418089

61. Ccg-38796

62. Akos015965307

63. Tox21_111513_1

64. Ac-8045

65. Cs-1237

66. Sdccgmls-0066837.p001

67. Ncgc00178483-01

68. Ncgc00178483-02

69. Ncgc00178483-04

70. Ncgc00178483-05

71. Ncgc00178483-14

72. Ncgc00263659-01

73. As-15249

74. Hy-17411

75. L0258

76. Limonin, From Citrus Seeds, >90% (hplc)

77. N1349

78. S2319

79. C03514

80. 180l718

81. A854522

82. Q-100083

83. Q2398745

84. Brd-k05906022-001-03-6

85. Brd-k05906022-001-05-1

86. Limone; Citrolimonin; Evodine; Dictamnolactone; Obaculactone

87. (4as,14br)-12-(furan-3-yl)-6,6,8a,12a-tetramethyldecahydro-1h,3h-oxireno[2,3-d]pyrano[4',3':3,3a]isobenzofuro[5,4-f]isochromene-3,8,10(6h,9ah)-trione

88. (4as,6ar,8ar,8br,9as,12r,12as,14ar,14br)-12-(furan-3-yl)-6,6,8a,12a-tetramethyldecahydro-3h-oxireno[d]pyrano[4',3':3,3a][2]benzofuro[5,4-f]isochromene-3,8,10(6h,9ah)-trione

89. 11h,13h-oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2h,5ah)-trione, 8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-, (2ar-(2aalpha,4abeta,4br,5aalpha,8alpha,8aalpha,10aalpha,10br*,14aalpha))-

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 470.5 g/mol
Molecular Formula C26H30O8
XLogP31.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count1
Exact Mass470.19406791 g/mol
Monoisotopic Mass470.19406791 g/mol
Topological Polar Surface Area105 Ų
Heavy Atom Count34
Formal Charge0
Complexity1010
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API Reference Price

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20-May-2023
03-Nov-2023
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ABOUT THIS PAGE

Limonin Manufacturers

A Limonin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Limonin, including repackagers and relabelers. The FDA regulates Limonin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Limonin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Limonin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Limonin Suppliers

A Limonin supplier is an individual or a company that provides Limonin active pharmaceutical ingredient (API) or Limonin finished formulations upon request. The Limonin suppliers may include Limonin API manufacturers, exporters, distributors and traders.

click here to find a list of Limonin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Limonin GMP

Limonin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Limonin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Limonin GMP manufacturer or Limonin GMP API supplier for your needs.

Limonin CoA

A Limonin CoA (Certificate of Analysis) is a formal document that attests to Limonin's compliance with Limonin specifications and serves as a tool for batch-level quality control.

Limonin CoA mostly includes findings from lab analyses of a specific batch. For each Limonin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Limonin may be tested according to a variety of international standards, such as European Pharmacopoeia (Limonin EP), Limonin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Limonin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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