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Chemistry

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Also known as:
Molecular Formula
C11H9N3NaO2+
Molecular Weight
238.20  g/mol
InChI Key
QWZUIMCIEOCSJF-CHHCPSLASA-N

Lipase
1 2D Structure

Lipase

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;(4Z)-3-hydroxy-4-(pyridin-2-ylhydrazinylidene)cyclohexa-2,5-dien-1-one
2.1.2 InChI
InChI=1S/C11H9N3O2.Na/c15-8-4-5-9(10(16)7-8)13-14-11-3-1-2-6-12-11;/h1-7,16H,(H,12,14);/q;+1/b13-9-;
2.1.3 InChI Key
QWZUIMCIEOCSJF-CHHCPSLASA-N
2.1.4 Canonical SMILES
C1=CC=NC(=C1)NN=C2C=CC(=O)C=C2O.[Na+]
2.1.5 Isomeric SMILES
C1=CC=NC(=C1)N/N=C\2/C=CC(=O)C=C2O.[Na+]
2.2 Create Date
2011-12-19
3 Chemical and Physical Properties
Molecular Weight 238.20 g/mol
Molecular Formula C11H9N3NaO2+
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass238.05924582 g/mol
Monoisotopic Mass238.05924582 g/mol
Topological Polar Surface Area74.6 A^2
Heavy Atom Count17
Formal Charge1
Complexity371
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameULTRESA
Active IngredientPANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
CompanyFOREST LABS INC (Application Number: N022222)

2 of 6  
Drug NameVIOKACE
Active IngredientPANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
CompanyFOREST LABS INC (Application Number: N022542)

3 of 6  
Drug NameZENPEP
Active IngredientPANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
CompanyFOREST LABS INC (Application Number: N022210. Patents: 7658918, 8221747, 8246950, 8562978, 8562979, 8562980, 8562981)

4 of 6  
Drug NameCREON
Active IngredientPANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
CompanyABBVIE (Application Number: N020725. Patent: 9198871)

5 of 6  
Drug NamePANCREAZE
Active IngredientPANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
CompanyJANSSEN PHARMS (Application Number: N022523. Patents: 8221747, 8562978, 8562979, 8562980, 8562981)

6 of 6  
Drug NamePERTZYE
Active IngredientPANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
CompanyDIGESTIVE CARE INC (Application Number: N022175)

API Reference Price

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MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"PANCREATIN","year":"2021","qtr":"Q2","strtotime":1620153000,"product":"PANCREATIN EC PELLETS 10000 UNITS LIPASE ACTIVITY","address":"210,A-WING, KANARA BUSINESS CENTRE,LAXMI NAGAR, GHATKOPAR (EAST)","city":"MUMBAI, MAHARASHTRA","supplier":"TITAN LABORATORIES","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"T.D E.A S.A.","customerCountry":"ARGENTINA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"245.1","totalValueFC":"48223.6","currency":"USD","unitRateINR":17661.726599999998,"date":"05-May-2021","totalValueINR":"3532345.32","totalValueInUsd":"48223.6","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"1582883","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pellets","supplierPort":"BOMBAY AIR","supplierAddress":"210,A-WING, KANARA BUSINESS CENTRE,LAXMI NAGAR, GHATKOPAR (EAST), MUMBAI, MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1666981800,"product":"PANCRELIPASE DELAYED RELEASE SPHERES (PA","address":"A\/01-GF & A\/101, PLOT NO.120, ANAND BHAVAN, SPECTRUM BLDG.,R.B.MEHTA Co","city":"MARG, GHATKOPAR EAST, MUMBAI, M.S.","supplier":"TITAN LABORATORIES","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"T.D E.A S.A.","customerCountry":"ARGENTINA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"255","totalValueFC":"48502.6","currency":"USD","unitRateINR":19955,"date":"29-Oct-2022","totalValueINR":"3991000","totalValueInUsd":"48502.6","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"5113404","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"A\/01-GF & A\/101, PLOT NO.120, ANAND BHAVAN, SPECTRUM BLDG.,R.B.MEHTA Co, MARG, GHATKOPAR EAST, MUMBAI, M.S.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1684693800,"product":"PANCRELIPASE DELAYED RELEASE SPHERES PANCREATIN EC PELLETS 10000 UNITS LIPASE ACTIVITY","address":"A\/01-GF & A\/101, PLOT NO.120, ANAND BHAVAN, SPECTRUM BLDG.,R.B.MEHTA Co","city":"MARG, GHATKOPAR EAST, MUMBAI, M.S.","supplier":"TITAN LABORATORIES","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"T D E A S A","customerCountry":"ARGENTINA","quantity":"150.00","actualQuantity":"150","unit":"KGS","unitRateFc":"255","totalValueFC":"36629.1","currency":"USD","unitRateINR":20093.333333333332,"date":"22-May-2023","totalValueINR":"3014000","totalValueInUsd":"36629.1","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"0","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pellets","supplierPort":"BOMBAY AIR","supplierAddress":"A\/01-GF & A\/101, PLOT NO.120, ANAND 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MAHARASHTRA","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1669746600,"product":"CHROMOGENIC SUBSTRATE FOR LIPASE - 11034618103 (FOR USE IN AUTO ANALYZER)","address":"501-B, SILVER UTOPIA CARDINAL GRACIOUS ROAD, CHAKALA","city":"ANDHERI EAST","supplier":"F. HOFFMANN-LA ROCHE","supplierCountry":"GERMANY","foreign_port":"NA","customer":"F. HOFFMANN-LA ROCHE","customerCountry":"INDIA","quantity":"0.04","actualQuantity":"0.04","unit":"KGS","unitRateFc":"886700","totalValueFC":"434.6","currency":"INR","unitRateINR":"886700","date":"30-Nov-2022","totalValueINR":"35468","totalValueInUsd":"434.6","indian_port":"MADRAS AIR","hs_no":"29349990","bill_no":"3528062","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"501-B, SILVER UTOPIA CARDINAL GRACIOUS ROAD, CHAKALA"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1671561000,"product":"CHROMOGENIC SUBSTRATE FOR LIPASE - 11034618103 (FOR USE IN AUTO ANALYZER)","address":"501-B, SILVER UTOPIA CARDINAL GRACIOUS ROAD, CHAKALA","city":"ANDHERI EAST","supplier":"F. 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LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SYNGENE INTERNATIONAL LIMITED","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2000","unit":"GMS","unitRateFc":"0.5","totalValueFC":"915.9","currency":"USD","unitRateINR":"37.7","date":"31-Mar-2023","totalValueINR":"75330","totalValueInUsd":"915.9","indian_port":"Biocon-SEZ","hs_no":"29420090","bill_no":"1004465","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ROOM 401, UNIT 3, BUILDING 10 NO 128, MINGDONG RD, CAOLU TOWN PUDONG SHANGHAI CHINA","customerAddress":"BIOCON SEZ, BIOCON PARK,PLOT NO.2 3"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1682533800,"product":"CHROMOGENIC SUBSTRATE FOR LIPASE -11034618103 (FOR USE IN AUTO ANALYZER)","address":"501-B, SILVER UTOPIA CARDINAL GRACIOUS ROAD, CHAKALA","city":"ANDHERI EAST","supplier":"F. HOFFMANN-LA ROCHE","supplierCountry":"GERMANY","foreign_port":"NA","customer":"F. HOFFMANN-LA ROCHE","customerCountry":"INDIA","quantity":"1.29","actualQuantity":"1.29","unit":"KGS","unitRateFc":"31995.3","totalValueFC":"503.6","currency":"INR","unitRateINR":"31995.4","date":"27-Apr-2023","totalValueINR":"41274","totalValueInUsd":"503.6","indian_port":"MADRAS AIR","hs_no":"29349990","bill_no":"5693621","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"501-B, SILVER UTOPIA CARDINAL GRACIOUS ROAD, CHAKALA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1687285800,"product":"11034618103 CHROMOGENIC SUBSTRATE FOR LIPASE","address":"501-B, SILVER UTOPIA CARDINAL GRACIOUS ROAD, CHAKALA","city":"ANDHERI EAST","supplier":"F. HOFFMANN-LA ROCHE","supplierCountry":"GERMANY","foreign_port":"NA","customer":"F. HOFFMANN-LA ROCHE","customerCountry":"INDIA","quantity":"0.36","actualQuantity":"0.36","unit":"KGS","unitRateFc":"305733.3","totalValueFC":"1339","currency":"INR","unitRateINR":"305733.5","date":"21-Jun-2023","totalValueINR":"110064.29","totalValueInUsd":"1339","indian_port":"MADRAS AIR","hs_no":"29349990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"501-B, SILVER UTOPIA CARDINAL GRACIOUS ROAD, CHAKALA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723746600,"product":"PHOSPHOLIPASE D 040 FOOD GRADE","address":"PLOT NO 64 SCHEME NO 97,RETIMANDI","city":"INDORE,MADHYA PRADESH","supplier":"XXOSYXXH GXXH","supplierCountry":"UNITED KINGDOM","foreign_port":"VIENNA DANUBEPIER HOV","customer":"SHANKAR NUTRICON PRIVATE ","customerCountry":"INDIA","quantity":"0.05","actualQuantity":"50","unit":"GMS","unitRateFc":"0.2","totalValueFC":"11.2","currency":"USD","unitRateINR":"18.8","date":"16-Aug-2024","totalValueINR":"939","totalValueInUsd":"11.2","indian_port":"Indore-EPZ\/SEZ","hs_no":"29232010","bill_no":"1006001","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED KINGDOM","selfForZScoreResived":"Pharma Grade","supplierPort":"VIENNA DANUBEPIER HOV","supplierAddress":"N\/A","customerAddress":"PLOT NO 64 SCHEME NO 97,RETIMANDI"}]
19-Feb-2021
16-Aug-2024
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