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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

2 API Suppliers, 2 Listed Suppliers, $ API Reference Price

2 API Suppliers
2 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

49 FDF Dossiers, 26 FDA Orange Book, 8 Europe, 15 Canada

49 FDF Dossiers
26 FDA Orange Book
8 Europe
15 Canada

GLOBAL SALES INFORMATION

8 Finished Drug Prices

globalSalesInformation
8 Finished Drug Prices

MARKET PLACE

1 APIs

marketPlace
1 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 187

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as:

Molecular Formula

C₁₁H₉N₃NaO₂+

Molecular Weight

238.20 g/mol

InChI Key

QWZUIMCIEOCSJF-CHHCPSLASA-N

1 2D Structure

Lipase

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

sodium;(4Z)-3-hydroxy-4-(pyridin-2-ylhydrazinylidene)cyclohexa-2,5-dien-1-one

2.1.2 InChI

InChI=1S/C11H9N3O2.Na/c15-8-4-5-9(10(16)7-8)13-14-11-3-1-2-6-12-11;/h1-7,16H,(H,12,14);/q;+1/b13-9-;

2.1.3 InChI Key

QWZUIMCIEOCSJF-CHHCPSLASA-N

2.1.4 Canonical SMILES

C1=CC=NC(=C1)NN=C2C=CC(=O)C=C2O.[Na+]

2.1.5 Isomeric SMILES

C1=CC=NC(=C1)N/N=C\2/C=CC(=O)C=C2O.[Na+]

2.2 Create Date

2011-12-19

3 Chemical and Physical Properties

Molecular Formula	C₁₁H₉N₃NaO₂+
Molecular Weight	238.20 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	238.05924582 g/mol
Monoisotopic Mass	238.05924582 g/mol
Topological Polar Surface Area	74.6 A^2
Heavy Atom Count	17
Formal Charge	1
Complexity	371
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 6
Drug Name	ULTRESA
Active Ingredient	PANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
Company	FOREST LABS INC (Application Number: N022222)

2 of 6
Drug Name	VIOKACE
Active Ingredient	PANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
Company	FOREST LABS INC (Application Number: N022542)

3 of 6
Drug Name	ZENPEP
Active Ingredient	PANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
Company	FOREST LABS INC (Application Number: N022210. Patents: 7658918, 8221747, 8246950, 8562978, 8562979, 8562980, 8562981)

4 of 6
Drug Name	CREON
Active Ingredient	PANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
Company	ABBVIE (Application Number: N020725. Patent: 9198871)

5 of 6
Drug Name	PANCREAZE
Active Ingredient	PANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
Company	JANSSEN PHARMS (Application Number: N022523. Patents: 8221747, 8562978, 8562979, 8562980, 8562981)

6 of 6
Drug Name	PERTZYE
Active Ingredient	PANCRELIPASE (AMYLASE;LIPASE;PROTEASE)
Company	DIGESTIVE CARE INC (Application Number: N022175)

API SUPPLIERS

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Listed Suppliers

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API Reference Price

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