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Chemistry

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Also known as: Vyvanse, 608137-33-3, Nrp-104, Lisdexamfetamine mesilate, Spd489, Tyvense
Molecular Formula
C17H33N3O7S2
Molecular Weight
455.6  g/mol
InChI Key
CETWSOHVEGTIBR-FORAGAHYSA-N
FDA UNII
SJT761GEGS

Lisdexamfetamine Dimesylate
A dextroamphetamine drug precursor that also functions as a CENTRAL NERVOUS SYSTEM STIMULANT and DOPAMINE UPTAKE INHIBITOR and is used in the treatment of ATTENTION DEFICIT HYPERACTIVITY DISORDER.
1 2D Structure

Lisdexamfetamine Dimesylate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2,6-diamino-N-[(2S)-1-phenylpropan-2-yl]hexanamide;methanesulfonic acid
2.1.2 InChI
InChI=1S/C15H25N3O.2CH4O3S/c1-12(11-13-7-3-2-4-8-13)18-15(19)14(17)9-5-6-10-16;2*1-5(2,3)4/h2-4,7-8,12,14H,5-6,9-11,16-17H2,1H3,(H,18,19);2*1H3,(H,2,3,4)/t12-,14-;;/m0../s1
2.1.3 InChI Key
CETWSOHVEGTIBR-FORAGAHYSA-N
2.1.4 Canonical SMILES
CC(CC1=CC=CC=C1)NC(=O)C(CCCCN)N.CS(=O)(=O)O.CS(=O)(=O)O
2.1.5 Isomeric SMILES
C[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)N.CS(=O)(=O)O.CS(=O)(=O)O
2.2 Other Identifiers
2.2.1 UNII
SJT761GEGS
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Dimesylate, Lis-dexamfetamine

2. Dimesylate, Lisdexamfetamine

3. Elvanse

4. Lis Dexamfetamine Dimesylate

5. Lis-dexamfetamine Dimesylate

6. Lisdexamfetamine

7. Nrp 104

8. Nrp-104

9. Nrp104

10. Vyvanse

2.3.2 Depositor-Supplied Synonyms

1. Vyvanse

2. 608137-33-3

3. Nrp-104

4. Lisdexamfetamine Mesilate

5. Spd489

6. Tyvense

7. Nrp104

8. Spd-489

9. Lisdexamfetamine Dimesylate [usan]

10. Lisdexamfetamine Dimesilate

11. Sjt761gegs

12. Lisdexamphetamine Dimesilate

13. L-lysine-d-amphetamine Dimesylate

14. Lisdexamfetamine Dimethanesulfonate

15. (2s)-2,6-diamino-n-[(1s)-1-methyl-2-phenylethyl]hexanamide Dimethanesulfonate

16. Lis-dexamfetamine Dimesylate

17. Lisdexamfetamine Mesilate (jan)

18. Lisdexamfetamine Dimesylate (usan)

19. Lisdexamfetamine Mesylate

20. Nrp 104

21. Lisdexamfetamine Mesilate [jan]

22. (2s)-2,6-diamino-n-[(2s)-1-phenylpropan-2-yl]hexanamide;methanesulfonic Acid

23. Unii-sjt761gegs

24. Venvanse

25. (2s)-2,6-diamino-n-((1s)-1-methyl-2-phenylethyl)hexanamide Dimethanesulfonate

26. Lys-amp

27. Spd 489

28. Lys-d-amp

29. Elvanse (tn)

30. Vyvanse (tn)

31. Schembl678421

32. Chembl1201178

33. Dtxsid60209653

34. Lisdexamfetamine Dimesylate Solution

35. Bcp24044

36. Akos030254940

37. Lisdexamfetamine Mesilate [mart.]

38. Ldx

39. Lisdexamfetamine Mesilate [who-dd]

40. Lisdexamfetamine Dimesylate [vandf]

41. D04747

42. Lisdexamfetamine Dimethanesulfonate [mi]

43. Lisdexamfetamine Dimesylate [orange Book]

44. 137l333

45. Q27289243

46. (2s)-2,6-diamino-n-((1s)-1-methyl-2-phenylethyl)hexanamide Dimethanesulphonate

47. Hexanamide, 2,6-diamino-n-((1s)-1-methyl-2-phenylethyl), (2s), Dimethanesulfonate

48. Hexanamide, 2,6-diamino-n-((1s)-1-methyl-2-phenylethyl), (2s), Dimethanesulphonate

49. Ldx;lisdexamfetamine Mesilate;lisdexamfetamine Mesylate;nrp 104;nrp-104;spd 489

50. Lisdexamfetamine Dimesylate Solution, 1.0 Mg/ml In Methanol (as Free Base), Ampule Of 1 Ml, Certified Reference Material

2.4 Create Date
2006-10-26
3 Chemical and Physical Properties
Molecular Weight 455.6 g/mol
Molecular Formula C17H33N3O7S2
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count9
Rotatable Bond Count8
Exact Mass455.17599275 g/mol
Monoisotopic Mass455.17599275 g/mol
Topological Polar Surface Area207 Ų
Heavy Atom Count29
Formal Charge0
Complexity344
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NameLisdexamfetamine dimesylate
Drug LabelVyvanse (lisdexamfetamine dimesylate), a CNS stimulant,isa capsule for once-a-day oral administration. The chemical designation for lisdexamfetamine dimesylate is (2S)-2,6-diamino-N-[(1S)-1-methyl-2-phenylethyl] hexanamide dimethanesulfonate....
Active IngredientLisdexamfetamine dimesylate
Dosage FormCapsule
RouteOral
Strength30mg; 50mg; 60mg; 40mg; 70mg; 20mg
Market StatusTentative Approval
CompanyMylan Pharms; Amneal Pharms; Roxane

2 of 4  
Drug NameVyvanse
PubMed HealthAmphetamine (By mouth)
Drug ClassesAmphetamine
Drug LabelVyvanse (lisdexamfetamine dimesylate), a CNS stimulant,isa capsule for once-a-day oral administration. The chemical designation for lisdexamfetamine dimesylate is (2S)-2,6-diamino-N-[(1S)-1-methyl-2-phenylethyl] hexanamide dimethanesulfonate....
Active IngredientLisdexamfetamine dimesylate
Dosage FormCapsule
RouteOral
Strength30mg; 50mg; 60mg; 40mg; 20mg; 70mg
Market StatusPrescription
CompanyShire Development

3 of 4  
Drug NameLisdexamfetamine dimesylate
Drug LabelVyvanse (lisdexamfetamine dimesylate), a CNS stimulant,isa capsule for once-a-day oral administration. The chemical designation for lisdexamfetamine dimesylate is (2S)-2,6-diamino-N-[(1S)-1-methyl-2-phenylethyl] hexanamide dimethanesulfonate....
Active IngredientLisdexamfetamine dimesylate
Dosage FormCapsule
RouteOral
Strength30mg; 50mg; 60mg; 40mg; 70mg; 20mg
Market StatusTentative Approval
CompanyMylan Pharms; Amneal Pharms; Roxane

4 of 4  
Drug NameVyvanse
PubMed HealthAmphetamine (By mouth)
Drug ClassesAmphetamine
Drug LabelVyvanse (lisdexamfetamine dimesylate), a CNS stimulant,isa capsule for once-a-day oral administration. The chemical designation for lisdexamfetamine dimesylate is (2S)-2,6-diamino-N-[(1S)-1-methyl-2-phenylethyl] hexanamide dimethanesulfonate....
Active IngredientLisdexamfetamine dimesylate
Dosage FormCapsule
RouteOral
Strength30mg; 50mg; 60mg; 40mg; 20mg; 70mg
Market StatusPrescription
CompanyShire Development

4.2 Drug Indication

Treatment of Attention Deficit Hyperactivity Disorder (ADHD)


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Central Nervous System Stimulants

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)


Dopamine Uptake Inhibitors

Drugs that block the transport of DOPAMINE into axon terminals or into storage vesicles within terminals. Most of the ADRENERGIC UPTAKE INHIBITORS also inhibit dopamine uptake. (See all compounds classified as Dopamine Uptake Inhibitors.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Central Nervous System Stimulation [PE]; Central Nervous System Stimulant [EPC]

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Lisdexamfetamine Dimesylate

About the Company : Veranova is a global leader in the development and manufacturing of specialist and complex APIs for pharma and biotech customers. We have over 50 years of experience navigating the...

Veranova is a global leader in the development and manufacturing of specialist and complex APIs for pharma and biotech customers. We have over 50 years of experience navigating the challenges of the global healthcare industry, and nurturing long-standing, trusted customer relationships. Operating within two divisions, Generics and Originators, we deliver a differentiated service offering to pharma and biotech customers for every stage in the drug development lifecycle. Macfarlan Smith Limited is trading as Veranova in the United Kingdom.
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About the Company : Founded in 1979, Noramco specializes in the development and manufacturing of APIs for both opioid and non-opioid products. With expertise in controlled substance development and ma...

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Lisdexamfetamine Dimesylate

About the Company : Tofigh Daru (TODACO) belongs to the Tamin Pharmaceutical Investment Company, the biggest pharmaceutical holding in Iran. TODACO develops novel APIs in therapeutic categories like A...

Tofigh Daru (TODACO) belongs to the Tamin Pharmaceutical Investment Company, the biggest pharmaceutical holding in Iran. TODACO develops novel APIs in therapeutic categories like Anti-cancer, Anti-diabetics, Cardiovascular & Narcotics. Today, we boast to be the one & only producer of specialized APIs like Glatiramer, Fentanyl, Remifentanil, Atracurium, and peptides including long-acting Triptorelin and we have 5 PIC/s GMP-approved production lines. We also produce semi-finished products, granules for hazardous substances & FDF know-how, tech transfers & CTD compilations. We are exporting our products to Turkey, Bulgaria, Russia, & Algeria.
Tofigh Daru

05

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Lisdexamfetamine Dimesylate

About the Company : Back in the year 1973, a team of individuals came up with such an idea – The idea called Alkem. Looking back at our 5 decades, illustrious journey, that one small idea has Not on...

Back in the year 1973, a team of individuals came up with such an idea – The idea called Alkem. Looking back at our 5 decades, illustrious journey, that one small idea has Not only triggered us to become one of India’s largest generic and specialty pharmaceutical company but also, create a foothold in over 40 countries. 29% of our revenue is generated via offshore sales and it has consistently been ranked amongst the top ten pharmaceutical companies in India. They have 20 manufacturing facilities at multiple locations in India and the United States of America.
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06

American Pharma Summit
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American Pharma Summit
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Lisdexamfetamine Dimesylate

About the Company : Established in 2016, a state-of-the-art R&D facility engaged in the development of Novel processes for Bulk Actives including Deuterated Actives, Advanced Intermediates and up the ...

Established in 2016, a state-of-the-art R&D facility engaged in the development of Novel processes for Bulk Actives including Deuterated Actives, Advanced Intermediates and up the value chain. With experience, Anvitha Life Care Private Limited has knowledge and expertise as a leader in chemical research. Every decision is inspired by our main mission, which is to provide the highest standard of product and services to our clients. In this rapidly changing industry, we’ve realized the importance of continually updating our approach to stay relevant in the market, and are committed to just that.
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07

American Pharma Summit
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American Pharma Summit
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lisdexamfetamine

About the Company : Chr. Olesen Synthesis is a Danish manufacturer of APIs and advanced intermediates. Chr. Olesen Synthesis was established in 2012 after the Chr. Olesen Group acquisition of the mult...

Chr. Olesen Synthesis is a Danish manufacturer of APIs and advanced intermediates. Chr. Olesen Synthesis was established in 2012 after the Chr. Olesen Group acquisition of the multi-purpose synthetic production facility just south of Copenhagen. Chr. Olesen Synthesis is initially active with API’s comprising of molecules like Hydromorphone, Codeine Phosphate, Pramipexole, Terbinafine Risedronate, Tolfenamic Acid, Amphetamine derivatives and advanced intermediates for Buprenorphine and Tamsulosin.
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08

American Pharma Summit
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Lisdexamfetamine

About the Company : Embio is today the world’s second largest Integrated manufacturer of Ephedrine and Pseudoephedrine salts Embio’s facility at Mahad ( 180 Kms from Bombay by road ) has been au...

Embio is today the world’s second largest Integrated manufacturer of Ephedrine and Pseudoephedrine salts Embio’s facility at Mahad ( 180 Kms from Bombay by road ) has been audited and approved by the Australian TGA, and the US FDA Embio has also been granted the Certificate of Suitability ( CoS ) for its Pseudoephedrine HCl
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09

J&H CHEM

China
American Pharma Summit
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J&H CHEM

China
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Lisdexamfetamine Dimesylate

About the Company : J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Valu...

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals, pharmaceuticals, and specialities. As a highly customer-oriented enterprise, we always believe "Customer first, service foremost", put forward innovation, continuously improve pipeline, integrate our broad range of products and services with our technical expertise, customise a competitive package to meet our customers' specific needs.
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10

Siegfried AG

Switzerland
American Pharma Summit
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Siegfried AG

Switzerland
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Lisdexamfetamine Dimesylate

About the Company : As an internationally renowned outsourcing partner, we offer products and tailor-made service packages that are seamlessly embedded in the value chain of our customers. Our pharmac...

As an internationally renowned outsourcing partner, we offer products and tailor-made service packages that are seamlessly embedded in the value chain of our customers. Our pharmaceutical industry partners benefit from a wide range of offers - from the development of active ingredients to development services for ready-made drugs, their approval and production to packaging and logistics. As a former fully integrated pharmaceutical company, Siegfried is now one of the few suppliers who can develop both active ingredients and ready-made drugs under one roof. This combination of experience and know-how is unique in the CDMO market.
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CHANDIGARH,? 160002","city":"N\/A","supplier":"SYNTHIMED LABS PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"ZAGREB","customer":"PLIVA HRVATSKA","customerCountry":"CROATIA","quantity":"540.00","actualQuantity":"540","unit":"KGS","unitRateFc":"3400","totalValueFC":"1809372.3","currency":"USD","unitRateINR":280087.71851851849,"date":"02-Jul-2024","totalValueINR":"151247368","totalValueInUsd":"1809372.3","indian_port":"Delhi Air","hs_no":"29214600","bill_no":"2112392","productDescription":"API","marketType":"REGULATED MARKET","country":"CROATIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Delhi Air","supplierAddress":"2nd, 3rd & 4th FLOOR, PALLADIUM TOWER, ,? PLOT NO.181\/46, INDUSTRIAL AREA PHASE-1, ,? CHANDIGARH , ?CHANDIGARH ,? CHANDIGARH,? 160002, N\/A","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720463400,"product":"LISDEXAMFETAMINE DIMESYLATE B.NO.P507040005 MD.MAY.2024 ED.APR.2029 P507040006 TO P507040008 MD.JUN.2024 ED.MAY.2029","address":"2nd, 3rd & 4th FLOOR, PALLADIUM TOWER, ,? PLOT NO.181\/46, INDUSTRIAL AREA PHASE-1, ,? CHANDIGARH , ?CHANDIGARH ,? CHANDIGARH,? 160002","city":"N\/A","supplier":"SYNTHIMED LABS PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"SANTIAGO DE CHILE -","customer":"LABORATORIOS RECALCINE S.A.","customerCountry":"CHILE","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"3613.5","totalValueFC":"1072376.1","currency":"USD","unitRateINR":298803.56333333335,"date":"09-Jul-2024","totalValueINR":"89641069","totalValueInUsd":"1072376.1","indian_port":"Delhi Air","hs_no":"29214600","bill_no":"2287111","productDescription":"API","marketType":"REGULATED MARKET","country":"CHILE","selfForZScoreResived":"Pharma Grade","supplierPort":"Delhi Air","supplierAddress":"2nd, 3rd & 4th FLOOR, PALLADIUM TOWER, ,? PLOT NO.181\/46, INDUSTRIAL AREA PHASE-1, ,? CHANDIGARH , ?CHANDIGARH ,? CHANDIGARH,? 160002, N\/A","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1721327400,"product":"LISDEXAMFETAMINE DIMESYLATE B.NO.P507040005 MD.MAY.2024 ED.APR.2029 P507040006 TO P507040008 MD.JUN.2024 ED.MAY.2029","address":"2nd, 3rd & 4th FLOOR, PALLADIUM TOWER, ,? PLOT NO.181\/46, INDUSTRIAL AREA PHASE-1, ,? CHANDIGARH , ?CHANDIGARH ,? CHANDIGARH,? 160002","city":"N\/A","supplier":"SYNTHIMED LABS PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"SANTIAGO DE CHILE -","customer":"LABORATORIOS RECALCINE S.A.","customerCountry":"CHILE","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"3613.5","totalValueFC":"1072376.1","currency":"USD","unitRateINR":298803.56333333335,"date":"19-Jul-2024","totalValueINR":"89641069","totalValueInUsd":"1072376.1","indian_port":"Delhi Air","hs_no":"29214600","bill_no":"2539586","productDescription":"API","marketType":"REGULATED MARKET","country":"CHILE","selfForZScoreResived":"Pharma Grade","supplierPort":"Delhi Air","supplierAddress":"2nd, 3rd & 4th FLOOR, PALLADIUM TOWER, ,? PLOT NO.181\/46, INDUSTRIAL AREA PHASE-1, ,? CHANDIGARH , ?CHANDIGARH ,? CHANDIGARH,? 160002, N\/A","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725906600,"product":"LISDEXAMFETAMINE DIMESYLATE BATCH NO.P507048012 MFG.DT.JUL.2024 EXP.DT.JUN.2029","address":"N\/A","city":"N\/A","supplier":"SYNTHIMED LABS PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"MONTEVIDEO -","customer":"NESTELCO S.A.","customerCountry":"URUGUAY","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"3762","totalValueFC":"37088.9","currency":"USD","unitRateINR":310809.69799999997,"date":"10-Sep-2024","totalValueINR":"3108096.98","totalValueInUsd":"37088.9","indian_port":"Delhi Air","hs_no":"29214600","bill_no":"3879953","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"URUGUAY","selfForZScoreResived":"Pharma Grade","supplierPort":"Delhi Air","supplierAddress":"N\/A, N\/A","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727461800,"product":"LISDEXAMFETAMINE DIMESYLATE BATCH NO.P507050001 MFG.DT.SEP.2024 EXP.DT.AUG.2029","address":"N\/A","city":"N\/A","supplier":"SYNTHIMED LABS PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"KYRO SRL","customerCountry":"ARGENTINA","quantity":"33.00","actualQuantity":"33","unit":"KGS","unitRateFc":"4300","totalValueFC":"139797.1","currency":"USD","unitRateINR":355005.01484848483,"date":"28-Sep-2024","totalValueINR":"11715165.49","totalValueInUsd":"139797.1","indian_port":"Delhi Air","hs_no":"29214600","bill_no":"4421113","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Delhi Air","supplierAddress":"N\/A, N\/A","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730140200,"product":"LISDEXAMFETAMINE DIMESYLATE B.NO. P507050002 TO P507050006 ,P507040020 TO P507040021 MFG.DT. SEP.2024 EXP.DT.AUG.2029","address":"2nd, 3rd & 4th FLOOR, PALLADIUM TOWER, ,? PLOT NO.181\/46, INDUSTRIAL AREA PHASE-1, ,? CHANDIGARH , ?CHANDIGARH ,? CHANDIGARH,? 160002","city":"N\/A","supplier":"SYNTHIMED LABS PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"ZAGREB","customer":"PLIVA HRVATSKA","customerCountry":"CROATIA","quantity":"615.00","actualQuantity":"615","unit":"KGS","unitRateFc":"3400","totalValueFC":"2065928.4","currency":"USD","unitRateINR":282264.77723577234,"date":"29-Oct-2024","totalValueINR":"173592838","totalValueInUsd":"2065928.4","indian_port":"Delhi Air","hs_no":"29214600","bill_no":"5237562","productDescription":"API","marketType":"REGULATED MARKET","country":"CROATIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Delhi Air","supplierAddress":"2nd, 3rd & 4th FLOOR, PALLADIUM TOWER, ,? PLOT NO.181\/46, INDUSTRIAL AREA PHASE-1, ,? CHANDIGARH , ?CHANDIGARH ,? CHANDIGARH,? 160002, N\/A","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1637778600,"product":"LISDEXAMFETAMINE DIMESYLATE IMPURITY 1 (RE-IMPORT) (RETURN FROM AIRPORT)","address":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,","city":"CHANDIGARH,CHANDIGARH","supplier":"LIBBS FARMACEUTICA","supplierCountry":"INDIA","foreign_port":"NA","customer":"IND SWIFT LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.03","unit":"GMS","unitRateFc":"50000","totalValueFC":"1643.8","currency":"USD","unitRateINR":"4080502","date":"25-Nov-2021","totalValueINR":"122415.06","totalValueInUsd":"1643.8","indian_port":"DELHI AIR","hs_no":"29214600","bill_no":"6405834","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1637778600,"product":"LISDEXAMFETAMINE DIMESYLATE IMPURITY 2-R (RE-IMPORT) (RETURNFROM AIRPORT)","address":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,","city":"CHANDIGARH,CHANDIGARH","supplier":"LIBBS FARMACEUTICA","supplierCountry":"INDIA","foreign_port":"NA","customer":"IND SWIFT LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.03","unit":"GMS","unitRateFc":"50000","totalValueFC":"1643.8","currency":"USD","unitRateINR":"4080496","date":"25-Nov-2021","totalValueINR":"122414.88","totalValueInUsd":"1643.8","indian_port":"DELHI AIR","hs_no":"29214600","bill_no":"6405834","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1637778600,"product":"LISDEXAMFETAMINE DIMESYLATE IMPURITY 2-R (RE-IMPORT) (RETURNFROM AIRPORT)","address":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,","city":"CHANDIGARH,CHANDIGARH","supplier":"LIBBS FARMACEUTICA","supplierCountry":"INDIA","foreign_port":"NA","customer":"IND SWIFT LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.12","unit":"GMS","unitRateFc":"60000","totalValueFC":"7890.2","currency":"USD","unitRateINR":"4896604.5","date":"25-Nov-2021","totalValueINR":"587592.54","totalValueInUsd":"7890.2","indian_port":"DELHI AIR","hs_no":"29214600","bill_no":"6405834","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1641493800,"product":"LISDEXAMFETAMINE DIMESYLATE IMPURITY 1 (RE-IMPORT) (RETURN FROM AIRPORT)","address":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,","city":"CHANDIGARH,CHANDIGARH","supplier":"LIBBS FARMACEUTICA","supplierCountry":"INDIA","foreign_port":"#N\/A","customer":"IND SWIFT LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.03","unit":"GMS","unitRateFc":"50000","totalValueFC":"1649.9","currency":"USD","unitRateINR":"4096802.7","date":"07-Jan-2022","totalValueINR":"122904.08","totalValueInUsd":"1649.9","indian_port":"DELHI AIR","hs_no":"29214600","bill_no":"6990941","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1641493800,"product":"LISDEXAMFETAMINE DIMESYLATE IMPURITY 2-R (RE-IMPORT) (RETURNFROM AIRPORT)","address":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,","city":"CHANDIGARH,CHANDIGARH","supplier":"LIBBS FARMACEUTICA","supplierCountry":"INDIA","foreign_port":"#N\/A","customer":"IND SWIFT LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.12","unit":"GMS","unitRateFc":"60000","totalValueFC":"7919.4","currency":"USD","unitRateINR":"4916164.8","date":"07-Jan-2022","totalValueINR":"589939.78","totalValueInUsd":"7919.4","indian_port":"DELHI AIR","hs_no":"29214600","bill_no":"6990941","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1651170600,"product":"LISDEXAMFETAMINE DIMESYLATE 2000 GRAMS (R AND D PURPOSE)","address":"ALKEM HOUSE, DEVASHISH ADJACENT T O,MATULYA CENTRE, SENAPATI BAPAT MA","city":"MUMBAI,MAHARASHTRA","supplier":"VERANOVA","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ALKEM LABORATORIES","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"5000","totalValueFC":"11235.1","currency":"USD","unitRateINR":"423839","date":"29-Apr-2022","totalValueINR":"847678.02","totalValueInUsd":"11235.1","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"8477756","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"ALKEM HOUSE, DEVASHISH ADJACENT T O,MATULYA CENTRE, SENAPATI BAPAT MA"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1664476200,"product":"LISDEXAMFETAMINE DIMESYLATE RS (RE IMPORT AFTER REJECTION FROM AIRPORT)","address":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,","city":"CHANDIGARH,CHANDIGARH","supplier":"TEVA PHARMACEUTICAL INDUSTRIES","supplierCountry":"INDIA","foreign_port":"NA","customer":"IND SWIFT LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"400","unit":"MGS","unitRateFc":"1","totalValueFC":"401.3","currency":"USD","unitRateINR":"80.4","date":"30-Sep-2022","totalValueINR":"32160","totalValueInUsd":"401.3","indian_port":"DELHI AIR","hs_no":"29214600","bill_no":"2681718","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,"}]
27-Jan-2021
29-Oct-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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FDA Orange Book

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01

NORWICH

U.S.A
Pharma Manufacturing 2024
Not Confirmed
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NORWICH

U.S.A
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Pharma Manufacturing 2024
Not Confirmed

LISDEXAMFETAMINE DIMESYLATE

Brand Name : LISDEXAMFETAMINE DIMESYLATE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 50MG

Approval Date : 2023-08-25

Application Number : 214547

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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02

AMNEAL

U.S.A
Pharma Manufacturing 2024
Not Confirmed
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AMNEAL

U.S.A
arrow
Pharma Manufacturing 2024
Not Confirmed

LISDEXAMFETAMINE DIMESYLATE

Brand Name : LISDEXAMFETAMINE DIMESYLATE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 20MG

Approval Date : 2023-08-25

Application Number : 202830

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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03

AMNEAL

U.S.A
Pharma Manufacturing 2024
Not Confirmed
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AMNEAL

U.S.A
arrow
Pharma Manufacturing 2024
Not Confirmed

LISDEXAMFETAMINE DIMESYLATE

Brand Name : LISDEXAMFETAMINE DIMESYLATE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 40MG

Approval Date : 2023-08-25

Application Number : 202830

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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04

APOTEX

Canada
Pharma Manufacturing 2024
Not Confirmed
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APOTEX

Canada
arrow
Pharma Manufacturing 2024
Not Confirmed

LISDEXAMFETAMINE DIMESYLATE

Brand Name : LISDEXAMFETAMINE DIMESYLATE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 50MG

Approval Date : 2023-08-25

Application Number : 216944

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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05

SPECGX LLC

Ireland
Pharma Manufacturing 2024
Not Confirmed
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SPECGX LLC

Ireland
arrow
Pharma Manufacturing 2024
Not Confirmed

LISDEXAMFETAMINE DIMESYLATE

Brand Name : LISDEXAMFETAMINE DIMESYLATE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 10MG

Approval Date : 2023-08-25

Application Number : 211840

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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06

MSN

India
Pharma Manufacturing 2024
Not Confirmed
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MSN

India
arrow
Pharma Manufacturing 2024
Not Confirmed

LISDEXAMFETAMINE DIMESYLATE

Brand Name : LISDEXAMFETAMINE DIMESYLATE

Dosage Form : TABLET, CHEWABLE;ORAL

Dosage Strength : 10MG

Approval Date : 2024-02-02

Application Number : 218306

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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07

PRINSTON INC

U.S.A
Pharma Manufacturing 2024
Not Confirmed
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PRINSTON INC

U.S.A
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Pharma Manufacturing 2024
Not Confirmed

LISDEXAMFETAMINE DIMESYLATE

Brand Name : LISDEXAMFETAMINE DIMESYLATE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 10MG

Approval Date : 2023-08-25

Application Number : 216266

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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08

SANDOZ

Switzerland
Pharma Manufacturing 2024
Not Confirmed
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SANDOZ

Switzerland
arrow
Pharma Manufacturing 2024
Not Confirmed

LISDEXAMFETAMINE DIMESYLATE

Brand Name : LISDEXAMFETAMINE DIMESYLATE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 20MG

Approval Date : 2024-07-26

Application Number : 202836

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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09

Pharma Manufacturing 2024
Not Confirmed
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arrow
Pharma Manufacturing 2024
Not Confirmed

LISDEXAMFETAMINE DIMESYLATE

Brand Name : LISDEXAMFETAMINE DIMESYLATE

Dosage Form : TABLET, CHEWABLE;ORAL

Dosage Strength : 50MG

Approval Date : 2023-08-25

Application Number : 214134

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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10

Pharma Manufacturing 2024
Not Confirmed
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arrow
Pharma Manufacturing 2024
Not Confirmed

LISDEXAMFETAMINE DIMESYLATE

Brand Name : VYVANSE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 30MG

Approval Date : 2007-02-23

Application Number : 21977

RX/OTC/DISCN : RX

RLD : Yes

TE Code : AB

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - CAPSULE;ORAL - 10MG

USFDA APPLICATION NUMBER - 21977

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DOSAGE - CAPSULE;ORAL - 20MG

USFDA APPLICATION NUMBER - 21977

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DOSAGE - CAPSULE;ORAL - 30MG

USFDA APPLICATION NUMBER - 21977

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DOSAGE - CAPSULE;ORAL - 40MG

USFDA APPLICATION NUMBER - 21977

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DOSAGE - CAPSULE;ORAL - 50MG

USFDA APPLICATION NUMBER - 21977

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DOSAGE - CAPSULE;ORAL - 60MG

USFDA APPLICATION NUMBER - 21977

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DOSAGE - CAPSULE;ORAL - 70MG

USFDA APPLICATION NUMBER - 21977

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Patents & EXCLUSIVITIES

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Health Canada Patents

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01

arrow
euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

Lisdexamfetamine Dimesylate

Brand Name : VYVANSE

Patent Number : 2527646

Filing Date : 2004-06-01

Strength per Unit : 60 mg

Dosage Form : Capsule

Human Or VET : Human

Route of Administration : Oral

Patent Expiration Date : 2024-06-01

Date Granted : 2011-08-23

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02

arrow
euroPLX 86 Munich
Not Confirmed
arrow
euroPLX 86 Munich
Not Confirmed

Lisdexamfetamine Dimesylate

Brand Name : VYVANSE

Patent Number : 2527646

Filing Date : 2004-06-01

Strength per Unit : 30 mg

Dosage Form : Capsule

Human Or VET : Human

Route of Administration : Oral

Patent Expiration Date : 2024-06-01

Date Granted : 2011-08-23

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03

arrow
euroPLX 86 Munich
Not Confirmed
arrow
euroPLX 86 Munich
Not Confirmed

Lisdexamfetamine Dimesylate

Brand Name : VYVANSE

Patent Number : 2527646

Filing Date : 2004-06-01

Strength per Unit : 50 mg

Dosage Form : Capsule

Human Or VET : Human

Route of Administration : Oral

Patent Expiration Date : 2024-06-01

Date Granted : 2011-08-23

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04

arrow
euroPLX 86 Munich
Not Confirmed
arrow
euroPLX 86 Munich
Not Confirmed

Lisdexamfetamine Dimesylate

Brand Name : VYVANSE

Patent Number : 2527646

Filing Date : 2004-06-01

Strength per Unit : 20 mg

Dosage Form : Capsule

Human Or VET : Human

Route of Administration : Oral

Patent Expiration Date : 2024-06-01

Date Granted : 2011-08-23

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05

arrow
euroPLX 86 Munich
Not Confirmed
arrow
euroPLX 86 Munich
Not Confirmed

Lisdexamfetamine Dimesylate

Brand Name : VYVANSE

Patent Number : 2527646

Filing Date : 2004-06-01

Strength per Unit : 40 mg

Dosage Form : Capsule

Human Or VET : Human

Route of Administration : Oral

Patent Expiration Date : 2024-06-01

Date Granted : 2011-08-23

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06

arrow
euroPLX 86 Munich
Not Confirmed
arrow
euroPLX 86 Munich
Not Confirmed

Lisdexamfetamine Dimesylate

Brand Name : VYVANSE

Patent Number : 2527646

Filing Date : 2004-06-01

Strength per Unit : 10mg

Dosage Form : CAPSULE

Human Or VET : Human

Route of Administration : ORAL

Patent Expiration Date : 2024-06-01

Date Granted : 2011-08-23

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07

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euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

Lisdexamfetamine Dimesylate

Brand Name : VYVANSE

Patent Number : 2527646

Filing Date : 2004-06-01

Strength per Unit : 70 mg

Dosage Form : CAPSULE

Human Or VET : Human

Route of Administration : ORAL

Patent Expiration Date : 2024-06-01

Date Granted : 2011-08-23

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