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ACTIVE PHARMA INGREDIENTS

4 API Suppliers, 3 USDMF, 1 Listed Suppliers

4 API Suppliers
3 USDMF
1 Listed Suppliers

MARKET PLACE

2 APIs

marketPlace
2 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

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Canada

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Chemistry

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Also known as: Lisuride hydrogen maleate, 19875-60-6, Lisuride maleate [jan], Lysenyl hydrogen maleate, Uv1635n8xw, R(+)-lisuride hydrogen maleate

Molecular Formula

C₂₄H₃₀N₄O₅

Molecular Weight

454.5 g/mol

InChI Key

CVQFAMQDTWVJSV-BAXNFHPCSA-N

FDA UNII

UV1635N8XW

An ergot derivative that acts as an agonist at dopamine D2 receptors (DOPAMINE AGONISTS). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (SEROTONIN RECEPTOR AGONISTS).

1 2D Structure

Lisuride Maleate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl]-1,1-diethylurea;(Z)-but-2-enedioic acid

2.1.2 InChI

InChI=1S/C20H26N4O.C4H4O4/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14;5-3(6)1-2-4(7)8/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,18+;/m0./s1

2.1.3 InChI Key

CVQFAMQDTWVJSV-BAXNFHPCSA-N

2.1.4 Canonical SMILES

CCN(CC)C(=O)NC1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C.C(=CC(=O)O)C(=O)O

2.1.5 Isomeric SMILES

CCN(CC)C(=O)N[C@@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C.C(=C\C(=O)O)\C(=O)O

2.2 Other Identifiers

2.2.1 UNII

UV1635N8XW

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Arolac

2. Carbamide, Methylergol

3. Cuvalit

4. Dopergin

5. Dopergine

6. Hydrochloride, Lisuride

7. Hydrogen Maleate, Lysuride

8. Lisuride

9. Lisuride Hydrochloride

10. Lisuride Maleate (1:1)

11. Lisuride Maleate, (8beta)-isomer

12. Lisuride Mesylate

13. Lisuride Phosphate (1:1)

14. Lisuride, (8alpha)-(+-)-isomer

15. Lysenyl

16. Lysurid

17. Lysuride Hydrogen Maleate

18. Maleate, Lisuride

19. Mesylate, Lisuride

20. Methylergol Carbamide

21. Revanil

2.3.2 Depositor-Supplied Synonyms

1. Lisuride Hydrogen Maleate

2. 19875-60-6

3. Lisuride Maleate [jan]

4. Lysenyl Hydrogen Maleate

5. Uv1635n8xw

6. R(+)-lisuride Hydrogen Maleate

7. Lisuride (maleate)

8. Lysuride Maleate

9. Cuvalit

10. Lysenyl

11. Lisuride Maleate (jan)

12. Lysenyl Bimaleate

13. 3-(9,10-didehydro-6-methylergolin-8-alpha-yl)-1,1-diethylurea Maleate (1:1)

14. 3-(9,10-didehydro-6-methylergolin-8-yl)-1,1-diethylurea Hydrogen Maleate

15. Urea, N'-((8-alpha)-9,10-didehydro-6-methylergolin-8-yl)-n,n-diethyl-, (z)-2-butenedioate

16. Chebi:31776

17. Urea, N'-[(8alpha)-9,10-didehydro-6-methylergolin-8-yl]-n,n-diethyl-, (2z)-2-butenedioate (1:1)

18. Einecs 243-387-3

19. Unii-uv1635n8xw

20. 1-((5r,8s)-6-methyl-9,10-didehydro-8-ergolinyl)-3,3-diethylurea Hydrogen Maleate

21. Lisuride Maleate [mi]

22. Schembl364392

23. Chembl1257128

24. Lisuride Maleate [mart.]

25. Lisuride Maleate [who-dd]

26. Dtxsid501017378

27. Akos025142010

28. Urea, 3-(9,10-didehydro-6-methylergolin-8-alpha-yl)-1,1-diethyl-, Maleate (1:1)

29. Hy-110080

30. Cs-0032924

31. D01462

32. Sr-01000075387

33. Sr-01000075387-1

34. Q27114683

35. N'-[(8?)-9,10-didehydro-6-methylergolin-8-yl]-n,n-diethylurea Maleate

36. 3-(9,10-didehydro-6-methylergolin-8.alpha.-yl)-1,1-diethylurea Maleate (1:1)

37. R(+)-n'-[(8alpha)-9,10-didehydro-6-methylergolin-8-yl]-n,n,-diethylurea Hydrogen Maleate

2.4 Create Date

2005-10-11

3 Chemical and Physical Properties

Molecular Formula	C₂₄H₃₀N₄O₅
Molecular Weight	454.5 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Exact Mass	454.22162007 g/mol
Monoisotopic Mass	454.22162007 g/mol
Topological Polar Surface Area	126 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	663
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Antiparkinson Agents

Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists. (See all compounds classified as Antiparkinson Agents.)

Serotonin Receptor Agonists

Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. (See all compounds classified as Serotonin Receptor Agonists.)

Dopamine Agonists

Drugs that bind to and activate dopamine receptors. (See all compounds classified as Dopamine Agonists.)

API SUPPLIERS

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ABOUT THIS PAGE

Lisuride Maleate Manufacturers

A Lisuride Maleate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Lisuride Maleate, including repackagers and relabelers. The FDA regulates Lisuride Maleate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Lisuride Maleate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Lisuride Maleate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Lisuride Maleate Suppliers

A Lisuride Maleate supplier is an individual or a company that provides Lisuride Maleate active pharmaceutical ingredient (API) or Lisuride Maleate finished formulations upon request. The Lisuride Maleate suppliers may include Lisuride Maleate API manufacturers, exporters, distributors and traders.

click here to find a list of Lisuride Maleate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Lisuride Maleate USDMF

A Lisuride Maleate DMF (Drug Master File) is a document detailing the whole manufacturing process of Lisuride Maleate active pharmaceutical ingredient (API) in detail. Different forms of Lisuride Maleate DMFs exist exist since differing nations have different regulations, such as Lisuride Maleate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Lisuride Maleate DMF submitted to regulatory agencies in the US is known as a USDMF. Lisuride Maleate USDMF includes data on Lisuride Maleate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Lisuride Maleate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Lisuride Maleate suppliers with USDMF on PharmaCompass.

Lisuride Maleate GMP

Lisuride Maleate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Lisuride Maleate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Lisuride Maleate GMP manufacturer or Lisuride Maleate GMP API supplier for your needs.

Lisuride Maleate CoA

A Lisuride Maleate CoA (Certificate of Analysis) is a formal document that attests to Lisuride Maleate's compliance with Lisuride Maleate specifications and serves as a tool for batch-level quality control.

Lisuride Maleate CoA mostly includes findings from lab analyses of a specific batch. For each Lisuride Maleate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Lisuride Maleate may be tested according to a variety of international standards, such as European Pharmacopoeia (Lisuride Maleate EP), Lisuride Maleate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Lisuride Maleate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.