Find Lobenzarit manufacturers, exporters & distributors on PharmaCompass

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Synopsis

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API REF. PRICE (USD/KG)

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Chemistry

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Also known as: Lobenzarit disodium, 64808-48-6, Lobenzarit disodium salt, Carfenil, Lobenzarit sodium [usan], Disodium 4-chloro-2,2'-iminodibenzoate
Molecular Formula
C14H8ClNNa2O4
Molecular Weight
335.65  g/mol
InChI Key
QPJBONAWFAURGB-UHFFFAOYSA-L
FDA UNII
7Z9SP74BXF

Lobenzarit
1 2D Structure

Lobenzarit

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
disodium;2-(2-carboxylatoanilino)-4-chlorobenzoate
2.1.2 InChI
InChI=1S/C14H10ClNO4.2Na/c15-8-5-6-10(14(19)20)12(7-8)16-11-4-2-1-3-9(11)13(17)18;;/h1-7,16H,(H,17,18)(H,19,20);;/q;2*+1/p-2
2.1.3 InChI Key
QPJBONAWFAURGB-UHFFFAOYSA-L
2.1.4 Canonical SMILES
C1=CC=C(C(=C1)C(=O)[O-])NC2=C(C=CC(=C2)Cl)C(=O)[O-].[Na+].[Na+]
2.2 Other Identifiers
2.2.1 UNII
7Z9SP74BXF
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-((2-carboxyphenyl)amino)-4-chlorobenzoic Acid

2. 4-chloro-2,2'-iminodibenzoic Acid

3. Cca Lobenzarit

4. Disodium 4-chloro-2,2'-iminodibenzoate

5. Lobenzarit

6. Lobenzarit Disodium

7. Lobenzarit, Disodium Salt

8. Lobenzart

9. N-(2-carboxyphenyl)-4-chloroanthranilic Acid

2.3.2 Depositor-Supplied Synonyms

1. Lobenzarit Disodium

2. 64808-48-6

3. Lobenzarit Disodium Salt

4. Carfenil

5. Lobenzarit Sodium [usan]

6. Disodium 4-chloro-2,2'-iminodibenzoate

7. Sodium 2-((2-carboxylatophenyl)amino)-4-chlorobenzoate

8. 7z9sp74bxf

9. 2-((2-carboxyphenyl)amino)-4-chlorobenzoic Acid Disodium Salt

10. Benzoic Acid, 2-((2-carboxyphenyl)amino)-4-chloro-, Disodium Salt

11. Cca

12. Disodium;2-(2-carboxylatoanilino)-4-chlorobenzoate

13. Benzoic Acid, 2-[(2-carboxyphenyl)amino]-4-chloro, Disodium Salt

14. Ncgc00181760-01

15. Unii-7z9sp74bxf

16. Disodium 4-chloro-2,2'-iminobenzoate

17. Ccris 8090

18. Carfenil (tn)

19. N-(2-carboxyphenyl)-4-chloroanthranilic Acid Disodium Salt

20. Disodium Lobenzarit

21. Dsstox_cid_28532

22. Dsstox_rid_82804

23. Dsstox_gsid_48606

24. Schembl635305

25. Lobenzarit Sodium [jan]

26. Chembl2107179

27. Dtxsid8048606

28. Chebi:31778

29. Lobenzarit Sodium (jp17/usan)

30. Lobenzarit Sodium [mart.]

31. Lobenzarit Sodium [who-dd]

32. Tox21_112941

33. Mfcd00941422

34. Lobenzarit Disodium Salt [mi]

35. Akos025311428

36. Ac-26450

37. Cas-64808-48-6

38. L0278

39. D01808

40. H11986

41. A834889

42. Disodium N-(2-carboxyphenyl)-4-chloroanthranilate

43. Q27269066

44. Sodium 2-(2-carboxylatophenylamino)-4-chlorobenzoate

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 335.65 g/mol
Molecular Formula C14H8ClNNa2O4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass334.9937240 g/mol
Monoisotopic Mass334.9937240 g/mol
Topological Polar Surface Area92.3 Ų
Heavy Atom Count22
Formal Charge0
Complexity365
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adjuvants, Immunologic

Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. (See all compounds classified as Adjuvants, Immunologic.)


Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


Immunosuppressive Agents

Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. (See all compounds classified as Immunosuppressive Agents.)


ABOUT THIS PAGE

Lobenzarit Manufacturers

A Lobenzarit manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Lobenzarit, including repackagers and relabelers. The FDA regulates Lobenzarit manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Lobenzarit API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Lobenzarit Suppliers

A Lobenzarit supplier is an individual or a company that provides Lobenzarit active pharmaceutical ingredient (API) or Lobenzarit finished formulations upon request. The Lobenzarit suppliers may include Lobenzarit API manufacturers, exporters, distributors and traders.

click here to find a list of Lobenzarit suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Lobenzarit USDMF

A Lobenzarit DMF (Drug Master File) is a document detailing the whole manufacturing process of Lobenzarit active pharmaceutical ingredient (API) in detail. Different forms of Lobenzarit DMFs exist exist since differing nations have different regulations, such as Lobenzarit USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Lobenzarit DMF submitted to regulatory agencies in the US is known as a USDMF. Lobenzarit USDMF includes data on Lobenzarit's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Lobenzarit USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Lobenzarit suppliers with USDMF on PharmaCompass.

Lobenzarit GMP

Lobenzarit Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Lobenzarit GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Lobenzarit GMP manufacturer or Lobenzarit GMP API supplier for your needs.

Lobenzarit CoA

A Lobenzarit CoA (Certificate of Analysis) is a formal document that attests to Lobenzarit's compliance with Lobenzarit specifications and serves as a tool for batch-level quality control.

Lobenzarit CoA mostly includes findings from lab analyses of a specific batch. For each Lobenzarit CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Lobenzarit may be tested according to a variety of international standards, such as European Pharmacopoeia (Lobenzarit EP), Lobenzarit JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Lobenzarit USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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