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CHEMISTRY
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FINISHED DOSAGE FORMULATIONS

3 FDF Dossiers, 1 FDA Orange Book, 2 Europe

3 FDF Dossiers
1 FDA Orange Book
2 Europe

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 12 SPI Pharma, 1 Faran Shimi Pharmaceutical, 1 Gangwal Healthcare, 1 Pfanstiehl, 3 Actylis, 1 BASF, 1 Curia, 1 Finar, 2 Gangwal Chemicals, 1 Ingredion Pharma Solutions, 2 Kerry, 2 Microlex e.U, 1 Pluviaendo, 3 Roquette, 1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shijiazhuang Huaxu Pharmaceutical, 1 Sigachi Industries

relatedExcipients
1 Rochem International Inc
12 SPI Pharma
1 Faran Shimi Pharmaceutical
1 Gangwal Healthcare
1 Pfanstiehl
3 Actylis
1 BASF
1 Curia
1 Finar
2 Gangwal Chemicals
1 Ingredion Pharma Solutions
2 Kerry
2 Microlex e.U
1 Pluviaendo
3 Roquette
1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd
1 Shijiazhuang Huaxu Pharmaceutical
1 Sigachi Industries

EXCIPIENTS BY APPLICATIONS

17 Fillers, Diluents & Binders, 10 Chewable & Orodispersible Aids, 9 Direct Compression, 9 Taste Masking, 6 Parenteral, 4 Co-Processed Excipients, 3 Granulation, 3 Disintegrants & Superdisintegrants, 3 Solubilizers, 2 Thickeners and Stabilizers, 1 API Stability Enhancers

excipientsByApplications
17 Fillers, Diluents & Binders
10 Chewable & Orodispersible Aids
9 Direct Compression
9 Taste Masking
6 Parenteral
4 Co-Processed Excipients
3 Granulation
3 Disintegrants & Superdisintegrants
3 Solubilizers
2 Thickeners and Stabilizers
1 API Stability Enhancers

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow

media
1 DATA COMPILATION #PharmaFlow

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 3 Finished Drug Prices

globalSalesInformation
1 US Medicaid Prescriptions
3 Finished Drug Prices

MARKET PLACE

1 APIs

marketPlace
1 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

99,377

Annual Reports (USD Million)

Finished Drug Prices

36 RELATED EXCIPIENT COMPANIES

67EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Schembl24175, Chembl1201175, Dtxsid20979825, Akos015894824

Molecular Formula

C₁₅H₁₇ClN₄O₉

Molecular Weight

432.77 g/mol

InChI Key

KUGJPYZIWCRREB-UHFFFAOYSA-N

1 2D Structure

Lodoxamide Tromethamine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-amino-2-(hydroxymethyl)propane-1,3-diol;2-[2-chloro-5-cyano-3-(oxaloamino)anilino]-2-oxoacetic acid

2.1.2 InChI

InChI=1S/C11H6ClN3O6.C4H11NO3/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21;5-4(1-6,2-7)3-8/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21);6-8H,1-3,5H2

2.1.3 InChI Key

KUGJPYZIWCRREB-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1=C(C=C(C(=C1NC(=O)C(=O)O)Cl)NC(=O)C(=O)O)C#N.C(C(CO)(CO)N)O

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Schembl24175

2. Chembl1201175

3. Dtxsid20979825

4. Akos015894824

2.3 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₁₅H₁₇ClN₄O₉
Molecular Weight	432.77 g/mol
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	7
Exact Mass	432.0684058 g/mol
Monoisotopic Mass	432.0684058 g/mol
Topological Polar Surface Area	243 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	543
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Alomide
PubMed Health	Lodoxamide (Into the eye)
Drug Classes	Ophthalmologic Agent
Drug Label	ALOMIDE (lodoxamide tromethamine ophthalmic solution) 0.1% is a sterile ophthalmic solution containing the mast cell stabilizer lodoxamide tromethamine for topical administration to the eyes. Lodoxamide tromethamine is a white, crystalline, water-s...
Active Ingredient	Lodoxamide tromethamine
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	eq 0.1% base
Market Status	Prescription
Company	Alcon

2 of 2
Drug Name	Alomide
PubMed Health	Lodoxamide (Into the eye)
Drug Classes	Ophthalmologic Agent
Drug Label	ALOMIDE (lodoxamide tromethamine ophthalmic solution) 0.1% is a sterile ophthalmic solution containing the mast cell stabilizer lodoxamide tromethamine for topical administration to the eyes. Lodoxamide tromethamine is a white, crystalline, water-s...
Active Ingredient	Lodoxamide tromethamine
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	eq 0.1% base
Market Status	Prescription
Company	Alcon