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ACTIVE PHARMA INGREDIENTS

13 API Suppliers, 4 USDMF, 2 EU WC, 1 KDMF, 3 NDC API, 10 Listed Suppliers

13 API Suppliers
4 USDMF
2 EU WC
1 KDMF
3 NDC API
10 Listed Suppliers

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2 Drugs in Development

2 Drugs in Development

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2 FDF Dossiers
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DIGITAL CONTENT

3 DATA COMPILATION #PharmaFlow, 41 NEWS #PharmaBuzz

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3 DATA COMPILATION #PharmaFlow
41 NEWS #PharmaBuzz

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3 Annual Reports

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3 Annual Reports

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7 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

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3INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

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Listed Dossiers

2DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

107

Finished Drug Prices

136 RELATED EXCIPIENT COMPANIES

232EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Lorcaserin hcl, 846589-98-8, Lorqess, Lorcaserin (hydrochloride), Apd-356, Belviq

Molecular Formula

C₁₁H₁₅Cl₂N

Molecular Weight

232.15 g/mol

InChI Key

ITIHHRMYZPNGRC-QRPNPIFTSA-N

FDA UNII

0QJF08GDPE

1 2D Structure

Lorcaserin HCl

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(5R)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine;hydrochloride

2.1.2 InChI

InChI=1S/C11H14ClN.ClH/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9;/h2-3,6,8,13H,4-5,7H2,1H3;1H/t8-;/m0./s1

2.1.3 InChI Key

ITIHHRMYZPNGRC-QRPNPIFTSA-N

2.1.4 Canonical SMILES

CC1CNCCC2=C1C=C(C=C2)Cl.Cl

2.1.5 Isomeric SMILES

C[C@H]1CNCCC2=C1C=C(C=C2)Cl.Cl

2.2 Other Identifiers

2.2.1 UNII

0QJF08GDPE

2.3 Synonyms

2.3.1 MeSH Synonyms

1. (1r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine

2. 8-chloro-2,3,4,5-tetrahydro-1-methyl-1h-3-benzazepine

3. Apd 356

4. Apd-356

5. Apd356

6. Ar-10a

7. Belviq

8. Lorcaserin

2.3.2 Depositor-Supplied Synonyms

1. Lorcaserin Hcl

2. 846589-98-8

3. Lorqess

4. Lorcaserin (hydrochloride)

5. Apd-356

6. Belviq

7. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-benzo[d]azepine Hydrochloride

8. Apd356

9. Lorcaserin Hydrochloride [usan]

10. Belviq Xr

11. 0qjf08gdpe

12. Chebi:65350

13. (1r)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1h-3-benzazepine Hydrochloride

14. 846589-98-8 (hcl)

15. Belviq (tn)

16. (r)-1h-3-benzazepine,8-chloro-2,3,4,5-tetrahydro-1-methyl-,hydrochloride

17. Lorcaserin Hydrochloride (usan)

18. (1r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine Hydrochloride

19. Unii-0qjf08gdpe

20. Apd 356

21. Schembl173899

22. Chembl2095211

23. Dtxsid60233650

24. Act10402

25. Bcp22731

26. Ex-a1697

27. Lorcaserin Hydrochloride (>50% Ee)

28. Lorcaserin Hydrochloride [mi]

29. Mfcd09833667

30. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine Hydrochloride

31. Akos005145786

32. Ac-8945

33. Bcp9000859

34. Cs-0752

35. Ks-1439

36. 1h-3-benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-, Hydrochloride (1:1), (1r)-

37. Lorcaserin Hydrochloride [vandf]

38. Lorcaserin Hydrochloride [who-dd]

39. Lorcaserin Hydrochloride Anhydrous

40. Hy-15368

41. Sw219573-1

42. Lorcaserin Hydrochloride [orange Book]

43. D06613

44. Lorcaserin Hcl; Apd 356; Apd-356; Apd356;

45. Q27888442

46. (1r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepinium Chloride

47. (5r)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine;hydrochloride

48. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine Hydrochloride Salt

49. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-benzo[d]azepine Hydrochloride Hemihydrate

50. 1h-3-benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-, Hydrochloride, (1r)-

51. 1h-3-benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-,hydrochloride, (1r)-

2.4 Create Date

2006-10-26

3 Chemical and Physical Properties

Molecular Formula	C₁₁H₁₅Cl₂N
Molecular Weight	232.15 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	231.0581549 g/mol
Monoisotopic Mass	231.0581549 g/mol
Topological Polar Surface Area	12 Å²
Heavy Atom Count	14
Formal Charge	0
Complexity	172
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Belviq
PubMed Health	Lorcaserin (By mouth)
Drug Classes	Antiobesity Agent
Drug Label	BELVIQ (lorcaserin hydrochloride) is a serotonin 2C receptor agonist for oral administration used for chronic weight management. Its chemical name is (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate. The empirical f...
Active Ingredient	Lorcaserin hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	10mg
Market Status	Prescription
Company	Eisai

2 of 2
Drug Name	Belviq
PubMed Health	Lorcaserin (By mouth)
Drug Classes	Antiobesity Agent
Drug Label	BELVIQ (lorcaserin hydrochloride) is a serotonin 2C receptor agonist for oral administration used for chronic weight management. Its chemical name is (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate. The empirical f...
Active Ingredient	Lorcaserin hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	10mg
Market Status	Prescription
Company	Eisai