Find Lubiprostone manufacturers, exporters & distributors on PharmaCompass

Virtual Booth

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

19 API Suppliers, 12 USDMF, 4 JDMF, 2 EU WC, 7 NDC API, 10 Listed Suppliers, $ API Reference Price

19 API Suppliers
12 USDMF
4 JDMF
2 EU WC
7 NDC API
10 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

1 Drugs in Development

1 Drugs in Development

INTERMEDIATES

1 Intermediates Suppliers

1 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

12 FDF Dossiers, 12 FDA Orange Book

12 FDF Dossiers
12 FDA Orange Book

DRUG PRODUCT COMPOSITIONS

CAPSULE;ORAL - 24MCG, CAPSULE;ORAL - 8MCG

drugProductComposition
CAPSULE;ORAL - 24MCG
CAPSULE;ORAL - 8MCG

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 2 SPI Pharma, 6 DKSH, 1 Gangwal Healthcare, 1 Nanjing Well Pharmaceutical, 4 ACG Worldwide, 1 BASF, 1 Gangwal Chemicals, 3 Lonza Capsugel, 1 Qualicaps, 11 Roquette, 1 Shijiazhuang Huaxu Pharmaceutical, 1 Zhejiang Huakang Pharmaceutical

relatedExcipients
1 Rochem International Inc
2 SPI Pharma
6 DKSH
1 Gangwal Healthcare
1 Nanjing Well Pharmaceutical
4 ACG Worldwide
1 BASF
1 Gangwal Chemicals
3 Lonza Capsugel
1 Qualicaps
11 Roquette
1 Shijiazhuang Huaxu Pharmaceutical
1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

9 Film Formers & Plasticizers, 8 Empty Capsules, 8 Fillers, Diluents & Binders, 7 Coating Systems & Additives, 5 Taste Masking, 4 Thickeners and Stabilizers, 2 Chewable & Orodispersible Aids, 2 Coloring Agents, 2 Parenteral, 1 Solubilizers, 1 Topical, 1 Co-Processed Excipients, 1 Direct Compression, 1 Soft Gelatin

excipientsByApplications
9 Film Formers & Plasticizers
8 Empty Capsules
8 Fillers, Diluents & Binders
7 Coating Systems & Additives
5 Taste Masking
4 Thickeners and Stabilizers
2 Chewable & Orodispersible Aids
2 Coloring Agents
2 Parenteral
1 Solubilizers
1 Topical
1 Co-Processed Excipients
1 Direct Compression
1 Soft Gelatin

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 19 NEWS #PharmaBuzz

media
1 DATA COMPILATION #PharmaFlow
19 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

2 US Medicaid Prescriptions, 16 Annual Reports

globalSalesInformation
2 US Medicaid Prescriptions
16 Annual Reports

MARKET PLACE

6 APIs

marketPlace
6 APIs

PATENTS & EXCLUSIVITIES

9 US Patents, 4 Health Canada Patents

patents
9 US Patents
4 Health Canada Patents

Chirogate Lubiprostone

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 776,985

MARKET PLACE

API

FDF

1INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

1DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

138,574,312

Annual Reports (USD Million)

2,860

Finished Drug Prices

34 RELATED EXCIPIENT COMPANIES

52EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Amitiza, 333963-40-9, 136790-76-6, Ru-0211, Spi-0211, (2r,4ar,5r,7ar)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-heptanoic acid

Molecular Formula

C₂₀H₃₂F₂O₅

Molecular Weight

390.5 g/mol

InChI Key

WGFOBBZOWHGYQH-MXHNKVEKSA-N

FDA UNII

7662KG2R6K

Member of a bicyclic fatty acid class of compounds derived from PROSTAGLANDIN E1 involved in chloride channel gating.

Lubiprostone is a Chloride Channel Activator. The mechanism of action of lubiprostone is as a Chloride Channel Activator.

1 2D Structure

Lubiprostone

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid

2.1.2 InChI

InChI=1S/C20H32F2O5/c1-2-3-11-19(21,22)20(26)12-10-15-14(16(23)13-17(15)27-20)8-6-4-5-7-9-18(24)25/h14-15,17,26H,2-13H2,1H3,(H,24,25)/t14-,15-,17-,20-/m1/s1

2.1.3 InChI Key

WGFOBBZOWHGYQH-MXHNKVEKSA-N

2.1.4 Canonical SMILES

CCCCC(C1(CCC2C(O1)CC(=O)C2CCCCCCC(=O)O)O)(F)F

2.1.5 Isomeric SMILES

CCCCC([C@]1(CC[C@H]2[C@H](O1)CC(=O)[C@@H]2CCCCCCC(=O)O)O)(F)F

2.2 Other Identifiers

2.2.1 UNII

7662KG2R6K

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 0211, Ru

2. 0211, Spi

3. Amitiza

4. Prostan-1-oic Acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11alpha)-

5. Ru 0211

6. Ru-0211

7. Ru0211

8. Spi 0211

9. Spi-0211

10. Spi0211

2.3.2 Depositor-Supplied Synonyms

1. Amitiza

2. 333963-40-9

3. 136790-76-6

4. Ru-0211

5. Spi-0211

6. (2r,4ar,5r,7ar)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-heptanoic Acid

7. 7-((2r,4ar,5r,7ar)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic Acid

8. 333963-40-9 (hemiketal)

9. 7-[(2r,4ar,5r,7ar)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic Acid

10. Lubiprostone [usan]

11. 7-[(2r,4ar,5s,7ar)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic Acid

12. 7-[(1r,3r,6r,7r)-3-(1,1-difluoropentyl)-3-hydroxy-8-oxo-2-oxabicyclo[4.3.0]non-7-yl]heptanoic Acid

13. Amitiza (tn)

14. Bicyclic Lubiprostone

15. Lubiprostone Hemiketal

16. Lubiprostone Powder

17. Ncgc00183105-01

18. Lubiprostone (hemiketal)

19. Lubiprostone [mi]

20. Lubiprostone [inn]

21. Lubiprostone [jan]

22. Dsstox_cid_28565

23. Dsstox_rid_82837

24. Lubiprostone [vandf]

25. Dsstox_gsid_48639

26. Lubiprostone [mart.]

27. (-)-7-((2r,4ar,5r,7ar)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta(b)pyran-5-yl)heptanoic Acid

28. Lubiprostone [who-dd]

29. Schembl217184

30. Gtpl4242

31. Lubiprostone (jan/usan/inn)

32. Chembl1201134

33. Dtxsid80861338

34. Lubiprostone [orange Book]

35. Amy30093

36. Ex-a1771

37. Zinc4217732

38. Tox21_112986

39. Mfcd20268389

40. Akos015896639

41. Ac-1863

42. Db01046

43. Ncgc00183105-02

44. As-39360

45. Cas-136790-76-6

46. Cs-0009583

47. Cas# 333963-40-9

48. D04790

49. 963l409

50. A850935

51. A905955

52. J-006909

53. Q6695342

54. Prostan-1-oic Acid, 11,15-epoxy-16,16-difluoro-15-hydroxy-9-oxo-, (11alpha,15r)-

55. Prostan-1-oic Acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11.alpha.)-

56. 7-((2r,4ar,5r,7ar)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoicacid

57. 7-[(2r,4ar,5r,7ar)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[e]pyran-5-yl]heptanoic Acid

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₂₀H₃₂F₂O₅
Molecular Weight	390.5 g/mol
XLogP3	4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	11
Exact Mass	390.22178044 g/mol
Monoisotopic Mass	390.22178044 g/mol
Topological Polar Surface Area	83.8 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	525
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Amitiza
PubMed Health	Lubiprostone (By mouth)
Drug Classes	Laxative
Drug Label	Amitiza (lubiprostone) is a chloride channel activator for oral use.The chemical name for lubiprostone is ()-7-[(2 ,4a ,5 ,7a )-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[ ]pyran-5-yl]heptanoic acid. The molecular formula of lubipro...
Active Ingredient	Lubiprostone
Dosage Form	Capsule
Route	Oral
Strength	24mcg; 8mcg
Market Status	Prescription
Company	Sucampo Pharma

2 of 2
Drug Name	Amitiza
PubMed Health	Lubiprostone (By mouth)
Drug Classes	Laxative
Drug Label	Amitiza (lubiprostone) is a chloride channel activator for oral use.The chemical name for lubiprostone is ()-7-[(2 ,4a ,5 ,7a )-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[ ]pyran-5-yl]heptanoic acid. The molecular formula of lubipro...
Active Ingredient	Lubiprostone
Dosage Form	Capsule
Route	Oral
Strength	24mcg; 8mcg
Market Status	Prescription
Company	Sucampo Pharma

4.2 Drug Indication

For the treatment of chronic idiopathic constipation in the adult population. Also used for the treatment of irritable bowel syndrome with constipation in women who are 18 years of age or older.

FDA Label

Treatment of constipation

5 Pharmacology and Biochemistry

5.1 Pharmacology

Chronic idiopathic constipation is generally defined by infrequent or difficult passage of stool. The signs and symptoms associated with chronic idiopathic constipation (i.e., abdominal pain or discomfort, bloating, straining, and hard or lumpy stools) may be the result of abnormal colonic motility that can delay the transit of intestinal contents and impede the evacuation of rectal contents. One approach to the treatment of chronic idiopathic constipation is the secretion of fluid into the abdominal lumen through the activation of chloride channels in the apical membrane of the gastrointestinal epithelium. Lubiprostone is a locally acting chloride channel activator that increases intestinal chloride and fluid secretion without altering sodium and potassium concentrations in the serum.

5.2 MeSH Pharmacological Classification

Chloride Channel Agonists

A class of drugs that stimulate chloride ion influx through cell membrane channels. (See all compounds classified as Chloride Channel Agonists.)

5.3 FDA Pharmacological Classification

5.3.1 Active Moiety

LUBIPROSTONE

5.3.2 FDA UNII

7662KG2R6K

5.3.3 Pharmacological Classes

Chloride Channel Activators [MoA]; Chloride Channel Activator [EPC]

5.4 ATC Code

A - Alimentary tract and metabolism

A06 - Drugs for constipation

A06A - Drugs for constipation

A06AX - Other drugs for constipation

A06AX03 - Lubiprostone

5.5 Absorption, Distribution and Excretion

Absorption

Lubiprostone has low systemic availability following oral administration and concentrations of lubiprostone in plasma are below the level of quantitation (10 pg/mL).

Route of Elimination

Peak plasma concentration was shown to be around 1.14 hours, with a majority of the drug excreted in the urine within 48 hours. Lubiprostone and M3 are only detected in trace amounts in human feces.

5.6 Metabolism/Metabolites

The results of both human and animal studies indicate that lubiprostone is rapidly and extensively metabolized by 15-position reduction, α-chain β-oxidation, and ω-chain ω-oxidation. These biotransformations are not mediated by the hepatic cytochrome P450 system but rather appear to be mediated by the ubiquitously expressed carbonyl reductase. M3, a metabolite of lubiprostone in both humans and animals is formed by the reduction of the carbonyl group at the 15-hydroxy moiety that consists of both α-hydroxy and β-hydroxy epimers. M3 makes up less than 10% of the dose of radiolabeled lubiprostone.

5.7 Biological Half-Life

0.9 to 1.4 hours

5.8 Mechanism of Action

Lubiprostone acts by specifically activating ClC-2 chloride channels, which is a normal constituent of the apical membrane of the human intestine, in a protein kinase A action independent fashion. Activation of ClC-2 chloride channels causes an efflux of chloride ions into the lumen, which in turn leads to an efflux of sodium ions through a paracellular pathway to maintain isoelectric neutrality. As a result, water follows sodium into the lumen in order to maintain isotonic equilibrium, thereby increasing intestinal fluid secretion. By increasing intestinal fluid secretion, lubiprostone increases motility in the intestine, thereby increasing the passage of stool and alleviating symptoms associated with chronic idiopathic constipation. Activation of ClC-2 chloride channels may also stimulate the recovery of muscosal barrier function by restoring tight junction protein complexes in the intestine. Patch clamp cell studies in human cell lines have indicated that the majority of the beneficial biological activity of lubiprostone and its metabolites is observed only on the apical (luminal) portion of the gastrointestinal epithelium.

API SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

JDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

EU WC

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

NDC API

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

[{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1630348200,"product":"LUBIPROSTONE IH","address":"FLAT B-3\/33 B HIGHWAY VIEW CHS LTD ,JANU COMPOUND KURAR VILLAGE","city":"MALAD EAST MUMBAI,MAHARASHTRA","supplier":"FLAX LABORATORIES","supplierCountry":"INDIA","foreign_port":"KARACHI -","customer":"MARTIN DOW MARKER LIMITED.","customerCountry":"PAKISTAN","quantity":"20.00","actualQuantity":"20","unit":"GMS","unitRateFc":"1416.3","totalValueFC":"27518.1","currency":"USD","unitRateINR":102047.5,"date":"31-Aug-2021","totalValueINR":"2040950","totalValueInUsd":"27518.1","indian_port":"BOMBAY AIR","hs_no":"29375000","bill_no":"4253262","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"FLAT B-3\/33 B HIGHWAY VIEW CHS LTD ,JANU COMPOUND KURAR VILLAGE, MALAD EAST MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1633458600,"product":"PHARMACEUTICAL RAW MATERIAL LUBIPROSTONE","address":"407\/408,SHARDA CHAMBERS,NEW MARINE LINES,","city":"MUMBAI, MAHARASHTRA.","supplier":"BDR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"ALANPHARMA","customerCountry":"EGYPT","quantity":"40.00","actualQuantity":"0.04","unit":"KGS","unitRateFc":"950000","totalValueFC":"36736.4","currency":"USD","unitRateINR":68800000,"date":"06-Oct-2021","totalValueINR":"2752000","totalValueInUsd":"36736.4","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"5122858","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"407\/408,SHARDA CHAMBERS,NEW MARINE LINES,, MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1648060200,"product":"CUBI-3 (LUBIPROSTONE INTERMEDIATE)(3AR,3","address":"39-40 KIADB INDUSTRIAL AREA,ELECTR ONIC CITY PHASE II HOSUR ROAD","city":"BANGALORE,KARNATAKA","supplier":"AURIGENE PHARMACEUTICAL SERVICES","supplierCountry":"INDIA","foreign_port":"MANCHESTER","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"UNITED KINGDOM","quantity":"265.00","actualQuantity":"0.265","unit":"KGS","unitRateFc":"293762","totalValueFC":"100145","currency":"GBP","unitRateINR":28803773.584905658,"date":"24-Mar-2022","totalValueINR":"7633000","totalValueInUsd":"100145","indian_port":"HYDERABAD AIR","hs_no":"29375000","bill_no":"9172466","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"UNITED KINGDOM","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"39-40 KIADB INDUSTRIAL AREA,ELECTR ONIC CITY PHASE II HOSUR ROAD, BANGALORE,KARNATAKA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1655490600,"product":"PHARMACEUTICAL RAW MATERIAL-LUBIPROSTONE","address":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES","city":"MUMBAI,MAHARASHTRA","supplier":"BDR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"ALANPHARMA","customerCountry":"EGYPT","quantity":"30.00","actualQuantity":"0.03","unit":"KGS","unitRateFc":"547000","totalValueFC":"16048.1","currency":"USD","unitRateINR":41733333.333333336,"date":"18-Jun-2022","totalValueINR":"1252000","totalValueInUsd":"16048.1","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"2219299","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1657650600,"product":"PHARMACEUTICAL RAW MATERIAL-LUBIPROSTONE","address":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES","city":"MUMBAI,MAHARASHTRA","supplier":"BDR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"MEPHIN","customerCountry":"EGYPT","quantity":"19.00","actualQuantity":"0.019","unit":"KGS","unitRateFc":"1050000","totalValueFC":"19442.5","currency":"USD","unitRateINR":81368421.052631587,"date":"13-Jul-2022","totalValueINR":"1546000","totalValueInUsd":"19442.5","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"2788187","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1667327400,"product":"PHARMACEUTICAL RAW MATERIAL LUBIPROSTONE","address":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES","city":"MUMBAI,MAHARASHTRA","supplier":"BDR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"MEPHIN","customerCountry":"EGYPT","quantity":"21.00","actualQuantity":"0.021","unit":"KGS","unitRateFc":"1050000","totalValueFC":"22079.9","currency":"USD","unitRateINR":85809523.809523806,"date":"02-Nov-2022","totalValueINR":"1802000","totalValueInUsd":"22079.9","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"5197888","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1674412200,"product":"PHARMACEUTICAL RAW MATERIAL-LUBIPROSTONE","address":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES","city":"MUMBAI,MAHARASHTRA","supplier":"BDR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"ALANPHARMA","customerCountry":"EGYPT","quantity":"100.00","actualQuantity":"0.1","unit":"KGS","unitRateFc":"490000","totalValueFC":"48080.1","currency":"USD","unitRateINR":39310000,"date":"23-Jan-2023","totalValueINR":"3931000","totalValueInUsd":"48080.1","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"7188214","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q2","strtotime":1624818600,"product":"LUBIPROSTONE (TEST LIC NO. TL\/AZ\/21\/001181) FOR R & D PURPOSE NOT FOR SALE","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGARHIGHWAY SATELLITE CROSS ROADS,","city":"AHMEDABAD\/GUJRAT","supplier":"APOTEX INC","supplierCountry":"CANADA","foreign_port":"","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"2.01","actualQuantity":"2.01","unit":"GMS","unitRateFc":"1950","totalValueFC":"6000.3","currency":"USD","unitRateINR":"219551.6","date":"28-Jun-2021","totalValueINR":"441298.73","totalValueInUsd":"6000.3","indian_port":"BOMBAY AIR","hs_no":"29379090","bill_no":"4480640","productDescription":"API","marketType":"REGULATED MARKET","country":"CANADA","selfForZScoreResived":"Pharma Grade","supplierPort":"","supplierAddress":"","customerAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGARHIGHWAY SATELLITE CROSS ROADS,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1630521000,"product":"LUBIPROSTONE E032","address":"OLD NO.1\/63, NEW NO.1\/58,PUDUPAKKAM VILLAGE, VIA VANDALUR-KELAMBAKKAM","city":"ROAD, KELAMBAKKAM \/CHENNAI\/ TAMILNA","supplier":"EVERLIGHT CHEMICAL","supplierCountry":"TAIWAN","foreign_port":"#N\/A","customer":"PAR ACTIVE TECHNOLOGIES ","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"GMS","unitRateFc":"10000","totalValueFC":"10223.4","currency":"USD","unitRateINR":"752000","date":"02-Sep-2021","totalValueINR":"752000","totalValueInUsd":"10223.4","indian_port":"MADRAS AIR","hs_no":"29339990","bill_no":"5282286","productDescription":"API","marketType":"REGULATED MARKET","country":"TAIWAN","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"OLD NO.1\/63, NEW NO.1\/58,PUDUPAKKAM VILLAGE, VIA VANDALUR-KELAMBAKKAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1706034600,"product":"LUBIPROSTONE (IMPORT FOR EXPORT) IUPAC NAME: 7-[(1R,3R,6R,7R)-3-(1,1-DIFLUOROPENTYL)-3-HYDROXY-8-OXO-2-OXABICYCLO [4.3.0","address":"407\/408,SHARDA CHAMBERS,","city":"MUMBAI, MAHARASHTRA.","supplier":"HANGZHOU QICHUANG CHEMICAL","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"BDR PHARMACEUTICALS","customerCountry":"INDIA","quantity":"15.00","actualQuantity":"0.015","unit":"KGS","unitRateFc":"275000","totalValueFC":"4174.1","currency":"USD","unitRateINR":"23127500","date":"24-Jan-2024","totalValueINR":"346912.5","totalValueInUsd":"4174.1","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"9811297","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"ROOM 1204 , NO.46 TIANMUSHAN ROAD XIHU DISTRICT HANGZHOU , , CHINASDNF CHINA","customerAddress":"407\/408,SHARDA CHAMBERS,"}]