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    Also known as: 59729-32-7, Citalopram hbr, Celexa, Cipramil, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile hydrobromide, Elopram
    Molecular Formula
    C20H22BrFN2O
    Molecular Weight
    405.3  g/mol
    InChI Key
    WIHMBLDNRMIGDW-UHFFFAOYSA-N
    FDA UNII
    I1E9D14F36
    Citalopram Hydrobromide
    A furancarbonitrile that is one of the SELECTIVE SEROTONIN REUPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
    1 2D Structure

    Citalopram Hydrobromide

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile;hydrobromide
    2.1.2 InChI
    InChI=1S/C20H21FN2O.BrH/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;/h4-9,12H,3,10-11,14H2,1-2H3;1H
    2.1.3 InChI Key
    WIHMBLDNRMIGDW-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F.Br
    2.2 Other Identifiers
    2.2.1 UNII
    I1E9D14F36
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Celexa

    2. Citalopram

    3. Cytalopram

    4. Lu-10-171

    5. Lu10171

    6. Seropram

    2.3.2 Depositor-Supplied Synonyms

    1. 59729-32-7

    2. Citalopram Hbr

    3. Celexa

    4. Cipramil

    5. 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Hydrobromide

    6. Elopram

    7. Seropram

    8. Bonitrile Hbr

    9. Nitalapram Hbr

    10. Lu 10-171-b

    11. Citalopram (hydrobromide)

    12. Citalopram, Hydrobromide Salt

    13. Lu 10-171 Hbr

    14. 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3h-2-benzofuran-5-carbonitrile;hydrobromide

    15. Nsc-758684

    16. Citalopram (as Hydrobromide)

    17. 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile Hydrobromide

    18. I1e9d14f36

    19. Cipram

    20. (s)-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Hydrobromide

    21. Lu 10-171

    22. Lu-10-171-b

    23. Citalopram D4 Hbr

    24. 59729-32-7 (hbr)

    25. 1-(3-(dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile Monohydrobromide

    26. 5-isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, Monohydrobromide

    27. Prepram Hbr

    28. 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile Hydrobromide

    29. Smr000326936

    30. Citalopram Hydrobromide [usan]

    31. Lu-10-171

    32. Sr-01000003129

    33. 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Monohydrobromide

    34. Einecs 261-890-6

    35. C20h21fn2o.hbr

    36. Apertia

    37. Prisdal

    38. Lupram

    39. Sepram

    40. Unii-i1e9d14f36

    41. 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Hydrobromide

    42. Citalopram Hydrobromide [usan:usp]

    43. Celexa (tn)

    44. Mfcd02101306

    45. Cpd000326936

    46. Schembl1118

    47. Mls000758293

    48. Mls000860078

    49. Mls001401376

    50. Mls002222294

    51. Citalopram Hydrobromide (usp)

    52. Citalopram Hydrobromide Solution

    53. Chembl1200781

    54. Dtxsid40872344

    55. Pharmakon1600-01504172

    56. Citalopram Hydrogen Bromide- Bio-x

    57. Hy-b1287

    58. Lu-10-171b

    59. Citalopram Hydrobromide [mi]

    60. Tox21_500258

    61. Nsc758684

    62. S4749

    63. Zd 211

    64. Zd-211

    65. Citalopram Hydrobromide [hsdb]

    66. Akos005145738

    67. Ab10921

    68. Ac-1595

    69. Bcp9000537

    70. Ccg-101022

    71. Ccg-213271

    72. Citalopram Hydrobromide [mart.]

    73. Citalopram Hydrobromide [vandf]

    74. Cs-4735

    75. Ks-1043

    76. Lp00258

    77. Nc00272

    78. Nsc 758684

    79. Citalopram Hydrobromide [usp-rs]

    80. Citalopram Hydrobromide [who-dd]

    81. Ncgc00093717-01

    82. Ncgc00093717-02

    83. Ncgc00093717-03

    84. Ncgc00260943-01

    85. Bc164316

    86. Citalopram Hydrobromide, >=98% (hplc)

    87. Citalopram Hydrobromide [orange Book]

    88. Eu-0100258

    89. Ft-0600173

    90. Citalopram Hydrobromide [ep Monograph]

    91. Citalopram Hydrobromide [usp Impurity]

    92. C 7861

    93. C75790

    94. Citalopram Hydrobromide [usp Monograph]

    95. D00822

    96. 729c327

    97. A832439

    98. Q-200865

    99. Sr-01000003129-2

    100. Sr-01000003129-4

    101. W-105304

    102. Citalopram Hydrobromide 100 Microg/ml In Acetonitrile

    103. Q27280253

    104. Sr-01000003129-10

    105. Z1550648760

    106. Citalopram Hydrobromide 0.1 Mg/ml In Methanol (as Free Base)

    107. Citalopram Hydrobromide 1.0 Mg/ml In Methanol (as Free Base)

    108. Citalopram Hydrobromide, European Pharmacopoeia (ep) Reference Standard

    109. Citalopram Hydrobromide, United States Pharmacopeia (usp) Reference Standard

    110. 1-(3-(dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile Monohbr

    111. Citalopram For System Suitability, European Pharmacopoeia (ep) Reference Standard

    112. Citalopram Hydrobromide, Pharmaceutical Secondary Standard; Certified Reference Material

    113. 1-(3-dimethylamino-propyl)-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-5-carbonitrile Hydrobromide

    114. 1-(3-dimethylaminopropyl)-1-(4'-fluorophenyl)-1, 3-dihydroisobenzofuran-5-carbonitrile Hbr

    115. 1-(3-dimethylaminopropyl)-1-(4'-fluorophenyl)-1, 3-dihydroisobenzofuran-5-carbonitrile Hydrobromide

    116. 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitril E Hydrobromide

    117. 5-isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, Monohbr

    118. 5-isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, Hydrobromide (1:1)

    119. Citalopram Hydrobromide Solution, 1.0 Mg/ml In Methanol (as Free Base), Ampule Of 1 Ml, Certified Reference Material

    120. Citalopram Hydrobromide Solution, 100 Mug/ml In Methanol (as Free Base), Ampule Of 1 Ml, Certified Reference Material

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 405.3 g/mol
    Molecular Formula C20H22BrFN2O
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count5
    Exact Mass404.08995 g/mol
    Monoisotopic Mass404.08995 g/mol
    Topological Polar Surface Area36.3 Ų
    Heavy Atom Count25
    Formal Charge0
    Complexity466
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 4  
    Drug NameCelexa
    Active IngredientCitalopram hydrobromide
    Dosage FormTablet
    RouteOral
    Strengtheq 40mg base; eq 20mg base; eq 10mg base
    Market StatusPrescription
    CompanyForest Labs

    2 of 4  
    Drug NameCitalopram hydrobromide
    PubMed HealthCitalopram (By mouth)
    Drug ClassesAntidepressant
    Active IngredientCitalopram hydrobromide
    Dosage FormTablet; Capsule; Solution
    Routeorally disintegrating; Oral
    Strengtheq 40mg base; eq 10mg base/5ml; eq 20mg base; eq 10mg base; 40mg
    Market StatusPrescription
    CompanyMylan Pharms; Glenmark Generics; Silarx; Amneal Pharms Ny; Teva Pharms; Epic Pharma; Apotex; Aurobindo; Aurobindo Pharma; Sun Pharm Inds; Torrent Pharms; Dr Reddys Labs; Pliva; Invagen Pharms; Cipla; Mylan; Roxane; Biovail Labs Intl

    3 of 4  
    Drug NameCelexa
    Active IngredientCitalopram hydrobromide
    Dosage FormTablet
    RouteOral
    Strengtheq 40mg base; eq 20mg base; eq 10mg base
    Market StatusPrescription
    CompanyForest Labs

    4 of 4  
    Drug NameCitalopram hydrobromide
    PubMed HealthCitalopram (By mouth)
    Drug ClassesAntidepressant
    Active IngredientCitalopram hydrobromide
    Dosage FormTablet; Capsule; Solution
    Routeorally disintegrating; Oral
    Strengtheq 40mg base; eq 10mg base/5ml; eq 20mg base; eq 10mg base; 40mg
    Market StatusPrescription
    CompanyMylan Pharms; Glenmark Generics; Silarx; Amneal Pharms Ny; Teva Pharms; Epic Pharma; Apotex; Aurobindo; Aurobindo Pharma; Sun Pharm Inds; Torrent Pharms; Dr Reddys Labs; Pliva; Invagen Pharms; Cipla; Mylan; Roxane; Biovail Labs Intl

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Selective Serotonin Reuptake Inhibitors

    Compounds that specifically inhibit the reuptake of serotonin in the brain. (See all compounds classified as Selective Serotonin Reuptake Inhibitors.)

    Antidepressive Agents, Second-Generation

    A structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake. (See all compounds classified as Antidepressive Agents, Second-Generation.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Serotonin Uptake Inhibitors [MoA]; Serotonin Reuptake Inhibitor [EPC]

    API Reference Price

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    02-Jan-2021
    23-Feb-2025
    KGS
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    DOSAGE - TABLET;ORAL - EQ 10MG BASE

    USFDA APPLICATION NUMBER - 20822

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    ABOUT THIS PAGE

    Looking for 59729-32-7 / Citalopram Hydrobromide API manufacturers, exporters & distributors?

    Citalopram Hydrobromide manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Citalopram Hydrobromide API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Citalopram Hydrobromide manufacturer or Citalopram Hydrobromide supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Citalopram Hydrobromide manufacturer or Citalopram Hydrobromide supplier.

    PharmaCompass also assists you with knowing the Citalopram Hydrobromide API Price utilized in the formulation of products. Citalopram Hydrobromide API Price is not always fixed or binding as the Citalopram Hydrobromide Price is obtained through a variety of data sources. The Citalopram Hydrobromide Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Citalopram Hydrobromide

    Synonyms

    59729-32-7, Citalopram hbr, Celexa, Cipramil, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile hydrobromide, Elopram

    Cas Number

    59729-32-7

    Unique Ingredient Identifier (UNII)

    I1E9D14F36

    About Citalopram Hydrobromide

    A furancarbonitrile that is one of the SELECTIVE SEROTONIN REUPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.

    Lupram Manufacturers

    A Lupram manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Lupram, including repackagers and relabelers. The FDA regulates Lupram manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Lupram API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Lupram manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Lupram Suppliers

    A Lupram supplier is an individual or a company that provides Lupram active pharmaceutical ingredient (API) or Lupram finished formulations upon request. The Lupram suppliers may include Lupram API manufacturers, exporters, distributors and traders.

    click here to find a list of Lupram suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Lupram USDMF

    A Lupram DMF (Drug Master File) is a document detailing the whole manufacturing process of Lupram active pharmaceutical ingredient (API) in detail. Different forms of Lupram DMFs exist exist since differing nations have different regulations, such as Lupram USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Lupram DMF submitted to regulatory agencies in the US is known as a USDMF. Lupram USDMF includes data on Lupram's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Lupram USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Lupram suppliers with USDMF on PharmaCompass.

    Lupram CEP

    A Lupram CEP of the European Pharmacopoeia monograph is often referred to as a Lupram Certificate of Suitability (COS). The purpose of a Lupram CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Lupram EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Lupram to their clients by showing that a Lupram CEP has been issued for it. The manufacturer submits a Lupram CEP (COS) as part of the market authorization procedure, and it takes on the role of a Lupram CEP holder for the record. Additionally, the data presented in the Lupram CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Lupram DMF.

    A Lupram CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Lupram CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Lupram suppliers with CEP (COS) on PharmaCompass.

    Lupram WC

    A Lupram written confirmation (Lupram WC) is an official document issued by a regulatory agency to a Lupram manufacturer, verifying that the manufacturing facility of a Lupram active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Lupram APIs or Lupram finished pharmaceutical products to another nation, regulatory agencies frequently require a Lupram WC (written confirmation) as part of the regulatory process.

    click here to find a list of Lupram suppliers with Written Confirmation (WC) on PharmaCompass.

    Lupram NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Lupram as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Lupram API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Lupram as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Lupram and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Lupram NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Lupram suppliers with NDC on PharmaCompass.

    Lupram GMP

    Lupram Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Lupram GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Lupram GMP manufacturer or Lupram GMP API supplier for your needs.

    Lupram CoA

    A Lupram CoA (Certificate of Analysis) is a formal document that attests to Lupram's compliance with Lupram specifications and serves as a tool for batch-level quality control.

    Lupram CoA mostly includes findings from lab analyses of a specific batch. For each Lupram CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Lupram may be tested according to a variety of international standards, such as European Pharmacopoeia (Lupram EP), Lupram JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Lupram USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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