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Chemistry

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Also known as: 602-85-7, Lysergole, Ntr684z1az, Chembl39947, 1413-67-8, Chebi:60528
Molecular Formula
C16H18N2O
Molecular Weight
254.33  g/mol
InChI Key
BIXJFIJYBLJTMK-MEBBXXQBSA-N
FDA UNII
NTR684Z1AZ

Lysergol API
Lysergol is an alkaloid of the ergoline family that occurs as a minor constituent in some species of fungi (most within Claviceps), and in the morning glory family of plants (Convolvulaceae), including the hallucinogenic seeds of Rivea corymbosa (ololiuhqui), Argyreia nervosa (Hawaiian baby woodrose) and Ipomoea violacea. As it is derived from dimethylergoline, it is referred to as a clavine. Lysergol can be utilized as an intermediate in the manufacture of some ergoloid medicines. Long term exposure to some ergoline alkaloids can cause ergotism, a disease causing convulsive and gangrenous symptoms. (L1918, L1928)
1 2D Structure

Lysergol API

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(6aR,9R)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl]methanol
2.1.2 InChI
InChI=1S/C16H18N2O/c1-18-8-10(9-19)5-13-12-3-2-4-14-16(12)11(7-17-14)6-15(13)18/h2-5,7,10,15,17,19H,6,8-9H2,1H3/t10-,15-/m1/s1
2.1.3 InChI Key
BIXJFIJYBLJTMK-MEBBXXQBSA-N
2.1.4 Canonical SMILES
CN1CC(C=C2C1CC3=CNC4=CC=CC2=C34)CO
2.1.5 Isomeric SMILES
CN1C[C@@H](C=C2[C@H]1CC3=CNC4=CC=CC2=C34)CO
2.2 Other Identifiers
2.2.1 UNII
NTR684Z1AZ
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 9,10-didehydro-6-methylergoline-8b-methanol

2. Isolysergol

3. Lysergol, (8alpha)-isomer

2.3.2 Depositor-Supplied Synonyms

1. 602-85-7

2. Lysergole

3. Ntr684z1az

4. Chembl39947

5. 1413-67-8

6. Chebi:60528

7. [(6ar,9r)-7-methyl-6,6a,8,9-tetrahydro-4h-indolo[4,3-fg]quinolin-9-yl]methanol

8. ((6ar,9r)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinolin-9-yl)methanol

9. (6-methyl-9,10-didehydroergolin-8beta-yl)methanol

10. 9,10-didehydro-6-methyl-8-hydroxymethylergoline

11. (7-methyl-4,6,6a,7,8,9-hexahydro-indolo(4,3-fg)quinolin-9-yl)-methanol

12. (7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-9-yl)-methanol

13. [(6ar,9r)-7-methyl-6,6a,8,9-tetrahydro-4h-indolo[4,3-fg]quinoline-9-yl]methanol

14. Lol

15. Prestwick_308

16. Prestwick0_000454

17. Prestwick1_000454

18. Prestwick2_000454

19. Prestwick3_000454

20. Unii-ntr684z1az

21. Bspbio_000528

22. Gtpl123

23. Cid_14987

24. Mls001049075

25. Divk1c_000515

26. Schembl178071

27. Spbio_002467

28. Bpbio1_000582

29. Megxp0_001732

30. Acon0_000797

31. Acon1_000057

32. Hms501j17

33. Kbio1_000515

34. Ninds_000515

35. Hms1569k10

36. Hms2096k10

37. Hms2271m04

38. Hy-n6809

39. Tnp00316

40. Zinc3983953

41. Bdbm50016479

42. Akos030490884

43. Phytochem 12: 2435 (1973)

44. Idi1_000515

45. Smp1_000185

46. Ncgc00017367-01

47. As-18087

48. Smr000386913

49. Cs-0092658

50. E75857

51. A923435

52. Sr-01000758923

53. Q6710130

54. Sr-01000758923-3

55. Brd-k27871032-001-02-6

56. Brd-k27871032-001-04-2

57. ((6ar)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinolin-9-yl)methanol

2.3.3 Other Synonyms

1. Lysergol Api

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 254.33 g/mol
Molecular Formula C16H18N2O
XLogP32.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area39.3
Heavy Atom Count19
Formal Charge0
Complexity394
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antipsychotic Agents

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)


ABOUT THIS PAGE

Lysergol API Manufacturers

A Lysergol API manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Lysergol API, including repackagers and relabelers. The FDA regulates Lysergol API manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Lysergol API API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Lysergol API manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Lysergol API Suppliers

A Lysergol API supplier is an individual or a company that provides Lysergol API active pharmaceutical ingredient (API) or Lysergol API finished formulations upon request. The Lysergol API suppliers may include Lysergol API API manufacturers, exporters, distributors and traders.

click here to find a list of Lysergol API suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Lysergol API GMP

Lysergol API Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Lysergol API GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Lysergol API GMP manufacturer or Lysergol API GMP API supplier for your needs.

Lysergol API CoA

A Lysergol API CoA (Certificate of Analysis) is a formal document that attests to Lysergol API's compliance with Lysergol API specifications and serves as a tool for batch-level quality control.

Lysergol API CoA mostly includes findings from lab analyses of a specific batch. For each Lysergol API CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Lysergol API may be tested according to a variety of international standards, such as European Pharmacopoeia (Lysergol API EP), Lysergol API JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Lysergol API USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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