Synopsis
Synopsis
0
API Suppliers
0
USDMF
0
CEP/COS
0
JDMF
0
EU WC
0
KDMF
0
NDC API
0
VMF
0
Listed Suppliers
0
EDQM
0
USP
0
JP
0
Others
0
FDF Dossiers
0
FDA Orange Book
0
Europe
0
Canada
0
Australia
0
South Africa
0
Listed Dossiers
DRUG PRODUCT COMPOSITIONS
0
US Patents
0
US Exclusivities
0
Health Canada Patents
US Medicaid
NA
Annual Reports
NA
Regulatory FDF Prices
NA
0
API
0
FDF
0
Data Compilation #PharmaFlow
0
Stock Recap #PipelineProspector
0
Weekly News Recap #Phispers
0
News #PharmaBuzz
1. 2,4-dimethylphenol Potassium
2. 2,4-dimethylphenol Sodium
3. 2,4-dimethylphenol Titanium (+4)
4. 2,4-dmp
5. 2,4-xylenol
1. 105-67-9
2. 2,4-xylenol
3. M-xylenol
4. Phenol, 2,4-dimethyl-
5. 4,6-dimethylphenol
6. 1-hydroxy-2,4-dimethylbenzene
7. 4-hydroxy-1,3-dimethylbenzene
8. Rcra Waste Number U101
9. 2,4-dimethyl Phenol
10. Nsc 3829
11. 2,4-dimethyl-phenol
12. Chebi:34241
13. Nsc-3829
14. Mfcd00002233
15. 5od803c081
16. Dsstox_cid_1864
17. Dsstox_rid_76371
18. Dsstox_gsid_21864
19. Caswell No. 907a
20. Lysol Brand Disinfectant
21. Cas-105-67-9
22. Bulk Lysol Brand Disinfectant
23. Ccris 721
24. Hsdb 4253
25. 2,4-dmp
26. Gable-tite Dark Creosote (creola)
27. Benzene, 2,4-dimethyl-1-hydroxy-
28. Du Cor Concentrated Fly Insecticide
29. Gable-tite Light Creosote (creola)
30. Einecs 203-321-6
31. Rcra Waste No. U101
32. Epa Pesticide Chemical Code 086804
33. Brn 0636244
34. Ai3-17612
35. Unii-5od803c081
36. 2,4dimethylphenol
37. 2.4-dimethylphenol
38. 4-hydroxy-m-xylene
39. Ec 203-321-6
40. Schembl92167
41. 2,4-dimethylphenol, 98%
42. 4-06-00-03126 (beilstein Handbook Reference)
43. Mls002152861
44. Bidd:er0275
45. Chembl29878
46. Wln: Qr B1 D1
47. Dimethylphenol, 2,4-
48. 1,3-dimethyl-4-hydroxybenzene
49. 2,4-xylenol, >=98%
50. Dtxsid2021864
51. Nsc3829
52. 2,4-dimethylphenol 2,4-xylenol
53. Hms3039j10
54. Xylenol 2,4-dimethylphenol
55. 2,4-dimethylphenol [hsdb]
56. Act00460
57. Zinc1672873
58. Tox21_201787
59. Tox21_300051
60. Bbl011443
61. Stl146554
62. Akos000121556
63. Am62796
64. 2,4-dimethylphenol, Analytical Standard
65. Ncgc00091611-01
66. Ncgc00091611-02
67. Ncgc00091611-03
68. Ncgc00091611-04
69. Ncgc00091611-05
70. Ncgc00253938-01
71. Ncgc00259336-01
72. Xylenol 2,4-dimethylphenol [mi]
73. Ps-11923
74. Smr001224485
75. Db-010714
76. Metacresol Impurity F [ep Impurity]
77. D0774
78. Ft-0610239
79. 2,4-dimethylphenol 100 Microg/ml In Methanol
80. Q2437536
81. W-108780
82. 2,4-dimethylphenol, Pestanal(r), Analytical Standard
83. F0001-0111
84. N0d
Molecular Weight | 122.16 g/mol |
---|---|
Molecular Formula | C8H10O |
XLogP3 | 2.3 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 1 |
Rotatable Bond Count | 0 |
Exact Mass | 122.073164938 g/mol |
Monoisotopic Mass | 122.073164938 g/mol |
Topological Polar Surface Area | 20.2 Ų |
Heavy Atom Count | 9 |
Formal Charge | 0 |
Complexity | 90.6 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
SUBJECTS WERE EXPOSED TO M-XYLENE AT CONCN OF ABOUT 3.9 MMOL/CU M FOR 5 DAYS, 6 HR/DAY. RATE OF 2,4-XYLENOL EXCRETION SHORTLY AFTER EXPOSURE WAS ABOUT 1-2% OF THAT FOR METHYLHIPPURIC ACID EXCRETION AND PULMONARY EXCRETION OF UNCHANGED XYLENE WAS ABOUT 4% OF UPTAKE.
RIIHIMAKI V ET AL; SCAND J WORK ENVIRON HEALTH 5 (3): 217-31 (1979)
The concn of 2,4-dimethylphenol was determined /in/ several tissues of the rat after 6 hr constant iv infusion and after iv bolus injection. 2,4-dimethylphenol was distributed rapidly in the brain and liver, /and had/ high tissue-plasma concn ratios for the brain, liver, and fat. Accumulation of 2,4-dimethylphenol in these tissues was negligible.
PMID:7067652 Kata JS et al; Ecotoxicol Environ Saf 6 (1): 35-40 (1982)
FOLLOWING IV ADMIN OF 17 MG/KG OF THE 2,4-ISOMER TO RATS, THE BRAIN ACCUMULATED THE HIGHEST AMT ON A PER G BASIS, FOLLOWED BY FAT AND LIVER. RATIOS OF BRAIN, LIVER AND FAT TO PLASMA /CONCN/ WERE APPROX 1, 1.5 AND 2, RESPECTIVELY.
SOMANI SM; FED PROC FED AM SOC EXP BIOL 40 (3PT1): 698 (1981)
2,4-DIMETHYLPHENOL DISTRIBUTED RAPIDLY THROUGH THE BODY AFTER IV BOLUS ADMIN OF 30 MG/KG. PLASMA, LIVER AND FAT CONCN DISAPPEARED PRIOR TO 60 MIN BUT PERSISTED IN THE BRAIN.
SOMANI SM; FED PROC FED AM SOC EXP BIOL 40 (3PT1): 698 (1981)
Associations between o-cresol, p-cresol, m-cresol, 2,4-xylenol, 2,5-xylenol, 3,4-xylenol, and 3,5-xylenol exposure levels and urinary phenol excretion were examined in the coke facility industry. The subjects consisted of 76 exposed workers employed in the tar distillation process and 34 controls. ... Urinary metabolite levels were corrected for specific gravity and creatinine. The time weighted average exposure concentrations in the breathing zones of the tar distillation workers were ... 0.02 to 0.04 mg/cu m for xylenols. ... The urinary xylenol levels of exposed workers ranged from 0.12 to 0.97 mg/l with specific gravity correction. In control urine samples, the specific gravity corrected xylenol concentrations ranged from 25 x 10(-3) to 43 x 10(-3) mg/l. Significant correlations were observed between the ambient levels and urinary concentrations of phenol, o-cresol, and the xylenols, with coefficients ranging from 0.45 to 0.82. The author concludes that the biological monitoring of urinary xylenols may be used as a means of measuring xylenol exposure in coke facility workers.
PMID:9352337 Bieniek G; International Archives of Occupational and Environmental Health 70 (5): 334-40 (1997)
METABOLISM OF 2,4-DIMETHYLPHENOL IN ANIMALS IS VERY SIMILAR TO THAT OF CRESOLS ... .
National Research Council. Drinking Water & Health Volume 1. Washington, DC: National Academy Press, 1977., p. 730
Rats were admin 2,4-dimethylphenol for 6 hr constantly by iv infusion or iv bolus injection. 2,4-Dimethylphenol was rapidly metabolized to its conjugates (94.3%) within 30 min; the glucuronide constituted 53% and other conjugates 41% /in plasma/.
PMID:7067652 Kata JS et al; Ecotoxicol Environ Saf 6 (1): 35-40 (1982)
IN WORKERS SIMULTANEOUSLY EXPOSED TO ETHYLBENZENES AND XYLENES, 2,4-DIMETHYLPHENOL, A METABOLITE OF M-XYLENE, COULD NOT BE DETECTED.
PMID:437902 ANGERER J, LEHNERT G; INT ARCH OCCUP ENVIRON HEALTH 43 (2): 145-50 (1979)
HYDROXYLATION OF AROMATIC HYDROCARBONS WAS STUDIED FOLLOWING THEIR ORAL ADMINISTRATION TO RATS THAT ALSO RECEIVED A PURIFIED DIET CONTAINING NEOMYCIN TO REDUCE THE LEVELS OF NORMALLY OCCURRING SIMPLE URINARY PHENOLS. PHENOLIC METABOLITES WERE QUANTITATIVELY ESTIMATED IN HYDROLYZED URINE SAMPLES BY GAS CHROMATOGRAPHY. M-XYLENE ADMINISTERED AT A DOSE OF 100 MG/KG WAS METABOLIZED TO 2,4-DIMETHYLPHENOL TO THE EXTENT OF 0.9% OF THE DOSE GIVEN.
PMID:5422210 BAKKE OM, SCHELINE RR; TOXICOL APPL PHARMACOL 16 (3): 691-700 (1970)
For more Metabolism/Metabolites (Complete) data for 2,4-DIMETHYLPHENOL (6 total), please visit the HSDB record page.
2,4-Dimethylphenol is a known human metabolite of m-xylene.
S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560
ABOUT THIS PAGE
34
PharmaCompass offers a list of Lysol Brand disinfectant API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Lysol Brand disinfectant manufacturer or Lysol Brand disinfectant supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Lysol Brand disinfectant manufacturer or Lysol Brand disinfectant supplier.
PharmaCompass also assists you with knowing the Lysol Brand disinfectant API Price utilized in the formulation of products. Lysol Brand disinfectant API Price is not always fixed or binding as the Lysol Brand disinfectant Price is obtained through a variety of data sources. The Lysol Brand disinfectant Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Lysol Brand disinfectant manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Lysol Brand disinfectant, including repackagers and relabelers. The FDA regulates Lysol Brand disinfectant manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Lysol Brand disinfectant API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Lysol Brand disinfectant supplier is an individual or a company that provides Lysol Brand disinfectant active pharmaceutical ingredient (API) or Lysol Brand disinfectant finished formulations upon request. The Lysol Brand disinfectant suppliers may include Lysol Brand disinfectant API manufacturers, exporters, distributors and traders.
Lysol Brand disinfectant Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Lysol Brand disinfectant GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Lysol Brand disinfectant GMP manufacturer or Lysol Brand disinfectant GMP API supplier for your needs.
A Lysol Brand disinfectant CoA (Certificate of Analysis) is a formal document that attests to Lysol Brand disinfectant's compliance with Lysol Brand disinfectant specifications and serves as a tool for batch-level quality control.
Lysol Brand disinfectant CoA mostly includes findings from lab analyses of a specific batch. For each Lysol Brand disinfectant CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Lysol Brand disinfectant may be tested according to a variety of international standards, such as European Pharmacopoeia (Lysol Brand disinfectant EP), Lysol Brand disinfectant JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Lysol Brand disinfectant USP).