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1. 16674-78-5
2. Magnesium;diacetate;tetrahydrate
3. Magnesiumacetatetetrahydrate
4. Mfcd00149214
5. Magnesium Diacetate Tetrahydrate
6. Acetic Acid, Magnesium Salt, Tetrahydrate
7. I01g0ejc3b
8. Magnesium Diacetate Tetrahydrate; Magnesium(2+) Acetate Tetrahydrate
9. Magnesium Diethanoate Tetrahydrate
10. Unii-i01g0ejc3b
11. Magnesium Acetate Tetra Hydrate
12. Chembl3989858
13. Dtxsid60168170
14. Akos022185858
15. Db09409
16. Magnesium Acetate Tetrahydrate Acs Grade
17. Magnesium Acetate Tetrahydrate [mi]
18. Ft-0628071
19. Magnesium Acetate Tetrahydrate [vandf]
20. Magnesium Acetate Tetrahydrate, Puratronic(r)
21. Magnesium Acetate Tetrahydrate [who-dd]
22. Magnesium Acetate (mg(oac)2) Tetrahydrate
23. J-010308
24. Magnesium Acetate Tetrahydrate [ep Monograph]
25. Magnesium Acetate Tetrahydrate [orange Book]
26. Q27280179
27. Acetic Acid, Magnesium Salt, Hydrate (2:1:4)
28. Magnesium Acetate Tetrahydrate, Molecular Biology Grade
29. Magnesium Acetate Tetrahydrate, Trace Metals Grade 99.95%
| Molecular Weight | 214.45 g/mol |
|---|---|
| Molecular Formula | C4H14MgO8 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 0 |
| Exact Mass | 214.0539091 g/mol |
| Monoisotopic Mass | 214.0539091 g/mol |
| Topological Polar Surface Area | 84.3 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 25.5 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 7 |
Used as magnesium salf-containing laxatives to prevent constipation. It can bring synergistic effect to restore normal bowel function when using in combination with aluminum salts that induce bowel retention. Magnesium acetate tetrahydrate is used as a source of water and electrolytes when combined with dextrose and other salts to form intravenous infusions. This injection can be used for patients with carbohydrate or magnesium deficiency, insulin hypoglycemia, constipation or hypertension during pregnancy.
Magnesium is an essential cofactor for many enzymatic reactions such as protein synthesis and ATP production. It also participates in adenylyl cyclase pathway and tyrosine kinase signalling pathways. Magnesium may also play a role in regulating glucose metabolism. It serves as an essential cation for a number of biochemical processes involved in nerve signaling, bone mineralization and muscle contractions.
Absorption
Intestinal absorption is achieved mainly through passive diffusion.
Route of Elimination
Mainly renal exctretion, where up to 97% of magnesium may be excreted renally during hypermagnesemia.
Volume of Distribution
Magnesium ions display approximate volume of distribution of 0.2 to 0.4 L/kg
Elimination half-life has been reported to be 27.7 hours following an overdose of 400mEq magnesium in an adult.
Magnesium ions electrostatically stabilize the adenylyl cyclase complex and enhance its catalytic actions and production of cAMP. They also regulate the level of phosphorylation in various pathways by formation of transition state of phosphoryl transfer reaction by protein kinases and stabilize ATP binding to protein kinases via electrostatic interactions. Many metabolic enzymes involved in glycolysis and Krebs cycle are magnesium-dependent. Magnesium-containing laxatives cause diarrhea through water retention and increased fecal mass that stimulates peristalsis. When used as an electrolyte supplementation, magnesium acetate tetrahydrate induces diuresis and metabolic alkalinizing effect. Magnesium ions enhance reactivity of arteries to vasoconstrictors, promotes vasoconstriction, and increases peripheral resistance, leading to increased blood pressure through potential competition with calcium ions in the vascular system. Magnesium ions also regulate other ions entering and exiting the cell membrane by acting as a ligand in N-methyl-D-aspartate receptor.
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ABOUT THIS PAGE
A Magnesium Acetate Tetrahydrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Magnesium Acetate Tetrahydrate, including repackagers and relabelers. The FDA regulates Magnesium Acetate Tetrahydrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Magnesium Acetate Tetrahydrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Magnesium Acetate Tetrahydrate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Magnesium Acetate Tetrahydrate supplier is an individual or a company that provides Magnesium Acetate Tetrahydrate active pharmaceutical ingredient (API) or Magnesium Acetate Tetrahydrate finished formulations upon request. The Magnesium Acetate Tetrahydrate suppliers may include Magnesium Acetate Tetrahydrate API manufacturers, exporters, distributors and traders.
click here to find a list of Magnesium Acetate Tetrahydrate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Magnesium Acetate Tetrahydrate CEP of the European Pharmacopoeia monograph is often referred to as a Magnesium Acetate Tetrahydrate Certificate of Suitability (COS). The purpose of a Magnesium Acetate Tetrahydrate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Magnesium Acetate Tetrahydrate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Magnesium Acetate Tetrahydrate to their clients by showing that a Magnesium Acetate Tetrahydrate CEP has been issued for it. The manufacturer submits a Magnesium Acetate Tetrahydrate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Magnesium Acetate Tetrahydrate CEP holder for the record. Additionally, the data presented in the Magnesium Acetate Tetrahydrate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Magnesium Acetate Tetrahydrate DMF.
A Magnesium Acetate Tetrahydrate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Magnesium Acetate Tetrahydrate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.
click here to find a list of Magnesium Acetate Tetrahydrate suppliers with CEP (COS) on PharmaCompass.
Magnesium Acetate Tetrahydrate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Magnesium Acetate Tetrahydrate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Magnesium Acetate Tetrahydrate GMP manufacturer or Magnesium Acetate Tetrahydrate GMP API supplier for your needs.
A Magnesium Acetate Tetrahydrate CoA (Certificate of Analysis) is a formal document that attests to Magnesium Acetate Tetrahydrate's compliance with Magnesium Acetate Tetrahydrate specifications and serves as a tool for batch-level quality control.
Magnesium Acetate Tetrahydrate CoA mostly includes findings from lab analyses of a specific batch. For each Magnesium Acetate Tetrahydrate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Magnesium Acetate Tetrahydrate may be tested according to a variety of international standards, such as European Pharmacopoeia (Magnesium Acetate Tetrahydrate EP), Magnesium Acetate Tetrahydrate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Magnesium Acetate Tetrahydrate USP).
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