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    Chemistry

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    Also known as: 34717-03-8, Orotate magnesium, Magnesium;2,4-dioxo-1h-pyrimidine-6-carboxylate, Orotic acid, magnesium salt, Gi96w46m5a, Magnesium bis(2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylate)
    Molecular Formula
    C10H6MgN4O8
    Molecular Weight
    334.48  g/mol
    InChI Key
    QWLHYYKDLOVBNV-UHFFFAOYSA-L
    FDA UNII
    GI96W46M5A
    Magnesium Orotate
    Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. Orotic acid acts as a transporter that carries magnesium into the cells. It also exhibits antioxidant properties, since it is a key intermediate in the biosynthetic pathway of pyrimidines that promotes the synthesis of enzymes which act as free radical scavengers. Experiments investigating the potential cardioprotective actions of orotic acid in pathological heart conditions are still ongoing.
    1 2D Structure

    Magnesium Orotate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    magnesium;2,4-dioxo-1H-pyrimidine-6-carboxylate
    2.1.2 InChI
    InChI=1S/2C5H4N2O4.Mg/c2*8-3-1-2(4(9)10)6-5(11)7-3;/h2*1H,(H,9,10)(H2,6,7,8,11);/q;;+2/p-2
    2.1.3 InChI Key
    QWLHYYKDLOVBNV-UHFFFAOYSA-L
    2.1.4 Canonical SMILES
    C1=C(NC(=O)NC1=O)C(=O)[O-].C1=C(NC(=O)NC1=O)C(=O)[O-].[Mg+2]
    2.2 Other Identifiers
    2.2.1 UNII
    GI96W46M5A
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 34717-03-8

    2. Orotate Magnesium

    3. Magnesium;2,4-dioxo-1h-pyrimidine-6-carboxylate

    4. Orotic Acid, Magnesium Salt

    5. Gi96w46m5a

    6. Magnesium Bis(2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylate)

    7. Bis(1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylato-n3,o4)magnesium

    8. 27067-77-2

    9. Unii-gi96w46m5a

    10. Einecs 252-167-6

    11. Schembl159382

    12. Chembl3707282

    13. Dtxsid20905129

    14. Magnesium Orotate [who-dd]

    15. Akos005267180

    16. Ac-7503

    17. Db13786

    18. Magnesium, Bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-.kappa.n3,.kappa.o4)-, (t-4)-

    19. Ft-0682956

    20. A822363

    21. Q9053193

    22. Magnesium 2,6-dioxo-3h-pyrimidine-4-carboxylate

    23. 1h-azepine,1-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]hexahydro-

    24. Magnesium, Bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-kappan3,kappao4)-, (t-4)-

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 334.48 g/mol
    Molecular Formula C10H6MgN4O8
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count0
    Exact Mass334.0036049 g/mol
    Monoisotopic Mass334.0036049 g/mol
    Topological Polar Surface Area197 Ų
    Heavy Atom Count23
    Formal Charge0
    Complexity262
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Pharmacology and Biochemistry
    4.1 ATC Code

    A - Alimentary tract and metabolism

    A12 - Mineral supplements

    A12C - Other mineral supplements

    A12CC - Magnesium

    A12CC09 - Magnesium orotate

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    27-Mar-2021
    29-Nov-2024
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    ABOUT THIS PAGE

    Magnesium Orotate Manufacturers

    A Magnesium Orotate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Magnesium Orotate, including repackagers and relabelers. The FDA regulates Magnesium Orotate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Magnesium Orotate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Magnesium Orotate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Magnesium Orotate Suppliers

    A Magnesium Orotate supplier is an individual or a company that provides Magnesium Orotate active pharmaceutical ingredient (API) or Magnesium Orotate finished formulations upon request. The Magnesium Orotate suppliers may include Magnesium Orotate API manufacturers, exporters, distributors and traders.

    click here to find a list of Magnesium Orotate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Magnesium Orotate WC

    A Magnesium Orotate written confirmation (Magnesium Orotate WC) is an official document issued by a regulatory agency to a Magnesium Orotate manufacturer, verifying that the manufacturing facility of a Magnesium Orotate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Magnesium Orotate APIs or Magnesium Orotate finished pharmaceutical products to another nation, regulatory agencies frequently require a Magnesium Orotate WC (written confirmation) as part of the regulatory process.

    click here to find a list of Magnesium Orotate suppliers with Written Confirmation (WC) on PharmaCompass.

    Magnesium Orotate GMP

    Magnesium Orotate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Magnesium Orotate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Magnesium Orotate GMP manufacturer or Magnesium Orotate GMP API supplier for your needs.

    Magnesium Orotate CoA

    A Magnesium Orotate CoA (Certificate of Analysis) is a formal document that attests to Magnesium Orotate's compliance with Magnesium Orotate specifications and serves as a tool for batch-level quality control.

    Magnesium Orotate CoA mostly includes findings from lab analyses of a specific batch. For each Magnesium Orotate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Magnesium Orotate may be tested according to a variety of international standards, such as European Pharmacopoeia (Magnesium Orotate EP), Magnesium Orotate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Magnesium Orotate USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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