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    Chemistry

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    Also known as: Dl-mandelic acid, 90-64-2, 2-hydroxy-2-phenylacetic acid, 611-72-3, Phenylglycolic acid, Amygdalic acid
    Molecular Formula
    C8H8O3
    Molecular Weight
    152.15  g/mol
    InChI Key
    IWYDHOAUDWTVEP-UHFFFAOYSA-N
    FDA UNII
    NH496X0UJX
    Mandelic Acid
    Mandelic Acid is an aromatic alpha hydroxy acid used in the treatment of urinary tract infections and as an oral antibiotic.
    1 2D Structure

    Mandelic Acid

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-hydroxy-2-phenylacetic acid
    2.1.2 InChI
    InChI=1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)
    2.1.3 InChI Key
    IWYDHOAUDWTVEP-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=CC=C(C=C1)C(C(=O)O)O
    2.2 Other Identifiers
    2.2.1 UNII
    NH496X0UJX
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Mandelic Acid, (+-)-isomer

    2. Mandelic Acid, (11)c-labeled

    3. Mandelic Acid, (r)-isomer

    4. Mandelic Acid, (s)-isomer

    5. Mandelic Acid, Calcium (2:1) Salt

    6. Mandelic Acid, Monoammonium Salt

    7. Mandelic Acid, Monocalcium Salt

    8. Mandelic Acid, Monolithium Salt

    9. Mandelic Acid, Monosodium Salt

    10. Mandelic Acid, Monosodium Salt, (r)-isomer

    11. Mandelic Acid, Monosodium Salt, (s)-isomer

    2.3.2 Depositor-Supplied Synonyms

    1. Dl-mandelic Acid

    2. 90-64-2

    3. 2-hydroxy-2-phenylacetic Acid

    4. 611-72-3

    5. Phenylglycolic Acid

    6. Amygdalic Acid

    7. Paramandelic Acid

    8. Racemic Mandelic Acid

    9. Almond Acid

    10. Uromaline

    11. P-mandelic Acid

    12. (rs)-mandelic Acid

    13. 2-phenylglycolic Acid

    14. Hydroxy(phenyl)acetic Acid

    15. Phenylhydroxyacetic Acid

    16. Glycolic Acid, Phenyl-

    17. Alpha-hydroxyphenylacetic Acid

    18. Kyselina Mandlova

    19. 2-phenyl-2-hydroxyacetic Acid

    20. Dl-hydroxy(phenyl)acetic Acid

    21. (+/-)-mandelic Acid

    22. 2-hydroxy-2-phenyl-acetic Acid

    23. Benzeneacetic Acid, Alpha-hydroxy-

    24. Nsc 7925

    25. Benzeneacetic Acid, .alpha.-hydroxy-

    26. (+/-)-alpha-hydroxyphenylacetic Acid

    27. .alpha.-hydroxyphenylacetic Acid

    28. Alpha-hydroxy-alpha-toluic Acid

    29. Kyselina 2-fenyl-2-hydroxyethanova

    30. Nsc-7925

    31. Nh496x0ujx

    32. Chebi:35825

    33. (+-)-alpha-hydroxybenzeneacetic Acid

    34. Alpha-hydroxybenzeneacetic Acid

    35. .alpha.-hydroxy-.alpha.-toluic Acid

    36. .alpha.-toluic Acid, .alpha.-hydroxy-

    37. Ammonium Mandelate

    38. (+)-mandelate, Xxi

    39. Acido Mandelico

    40. (+-)-mandelic Acid

    41. Benzeneacetic Acid, Alpha-hydroxy-, Homopolymer

    42. 32518-00-6

    43. Benzeneacetic Acid, .alpha.-hydroxy-, (.+/-.)-

    44. Mandelic-acid

    45. 2-hydroy-2-phenylacetic Acid

    46. Mandelic Acid [usp]

    47. Dl-amygdalic Acid

    48. Dl-mandelicacid

    49. Acido Mandelico [italian]

    50. Dl-2-hydroxy-2-phenylacetic Acid

    51. Kyselina Mandlova [czech]

    52. (+-)-2-hydroxy-2-phenylethanoic Acid

    53. Alpha-toluic Acid, Alpha-hydroxy-

    54. (+-)-alpha-hydroxyphenylacetic Acid

    55. Einecs 202-007-6

    56. Einecs 210-277-1

    57. Unii-nh496x0ujx

    58. 2-hydroxy-2-phenylethanoic Acid

    59. Acidomandelico

    60. Alpha-hydroxybenzeneacetic Acid, (+-)-

    61. Ai3-06293

    62. Kyselina 2-fenyl-2-hydroxyethanova [czech]

    63. Mfcd00004495

    64. Mfcd00064251

    65. Benzoglycolic Acid

    66. Phenylacetic Acid, Alpha-hydroxy-

    67. Ncgc00166022-01

    68. L(+)mandelic Acid

    69. (+) Mandelic Acid

    70. (+)-mandelic Acid

    71. Ppcm

    72. Samma

    73. Hyroxyphenylacetic Acid

    74. Pregabalin Impurity C

    75. (+/-)-alpha-hydroxybenzeneacetic Acid

    76. Mandelic Acid, 99%

    77. (-)-mandelate, Xx

    78. Hydroxyphenyl Acetic Acid

    79. 81432-25-9

    80. Benzeneacetic Acid, .alpha.-hydroxy-, (.alpha.r)-

    81. Pregabalin Ep Impurity C

    82. Wln: Qyr&vq

    83. Hydroxy-phenyl-acetic Acid

    84. Mandelic Acid, >=99%

    85. Dl-mandelic Acid, 99%

    86. Mandelic Acid [mi]

    87. Schembl1050

    88. (.+/-.)-mandelic Acid

    89. Chembl1609

    90. (+)-phenylhydroxyacetic Acid

    91. (?)-phenylhydroxyacetic Acid

    92. 2-hydroxy-2-phenylaceticacid

    93. Mandelic Acid [inci]

    94. Mls001074208

    95. Mandelic Acid [mart.]

    96. Mandelic Acid [usp-rs]

    97. Mandelic Acid [who-dd]

    98. .alpha.-phenylhydroxyacetic Acid

    99. Dtxsid6023234

    100. Bdbm92715

    101. Nsc7925

    102. Mandelic Acid Condensation Polymer

    103. 2-oxidanyl-2-phenyl-ethanoic Acid

    104. Hms2230f19

    105. Hms3371m20

    106. Hms3373a03

    107. (2rs)-hydroxy(phenyl)ethanoic Acid

    108. Bbl028097

    109. Mfcd00064250

    110. S3363

    111. Stl283951

    112. Akos000118795

    113. Akos016050628

    114. Cs-w016307

    115. Db13218

    116. Hy-w015591

    117. Ks-1423

    118. Ncgc00166023-01

    119. Ncgc00166269-01

    120. (.+/-.)-alpha-hydroxybenzeneacetic Acid

    121. Ac-12228

    122. Smr000653543

    123. Sy001645

    124. Sy001670

    125. Db-016128

    126. Db-016158

    127. Ds-000887

    128. Am20060842

    129. Ft-0600010

    130. Ft-0601504

    131. Ft-0625487

    132. Ft-0628148

    133. M0038

    134. Benzeneacetic Acid, .alpha.-hydroxy-, ( )-

    135. Benzeneacetic Acid, .alpha.-hydroxy-, (s)-

    136. Phenylacetic Acid, .alpha.--hydroxy-

    137. A19434

    138. Dl-mandelic Acid, Analytical Reference Material

    139. Mls-0090887.0001

    140. A833072

    141. Ae-562/40233036

    142. Q412293

    143. (2rs)-2-hydroxy-2-phenylacetic Acid (mandelic Acid)

    144. Glycopyrronium Bromide Impurity C [ep Impurity]

    145. Mandelic Acid ((2rs)-2-hydroxy-2-phenylacetic Acid)

    146. 14a53e4a-8315-42a7-9d60-de06ccbb1af9

    147. F2191-0202

    148. Homatropine Hydrobromide Impurity C [ep Impurity]

    149. Z955123532

    150. Homatropine Methylbromide Impurity C [ep Impurity]

    151. Mandelic Acid, United States Pharmacopeia (usp) Reference Standard

    152. Mandelic Acid; (2rs)-2-hydroxy-2-phenylacetic Acid ; ?-hydroxy-benzeneacetic Acid;\

    2.4 Create Date
    2004-09-16
    3 Chemical and Physical Properties
    Molecular Weight 152.15 g/mol
    Molecular Formula C8H8O3
    XLogP30.6
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count2
    Exact Mass152.047344113 g/mol
    Monoisotopic Mass152.047344113 g/mol
    Topological Polar Surface Area57.5 Ų
    Heavy Atom Count11
    Formal Charge0
    Complexity138
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 ATC Code

    B - Blood and blood forming organs

    B05 - Blood substitutes and perfusion solutions

    B05C - Irrigating solutions

    B05CA - Antiinfectives

    B05CA06 - Mandelic acid

    J - Antiinfectives for systemic use

    J01 - Antibacterials for systemic use

    J01X - Other antibacterials

    J01XX - Other antibacterials

    J01XX06 - Mandelic acid

    API Reference Price

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LINGOTHAM (VI),"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725906600,"product":"D-MANDELIC ACID (ADC LIST SL.NO-512)","address":"7-2-A2, HETERO CORPORATE,","city":"HYDERABAD-A.P.","supplier":"JIANGXI KEYUAN BIOPHARM CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"HETERO DRUGS","customerCountry":"INDIA","quantity":"5000.00","actualQuantity":"5000","unit":"KGS","unitRateFc":"14.5","totalValueFC":"73073.7","currency":"USD","unitRateINR":"1224.7","date":"10-Sep-2024","totalValueINR":"6123665.85","totalValueInUsd":"73073.7","indian_port":"Madras Sea","hs_no":"29181990","bill_no":"5518484","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"JISHAN INDUSTRIAL ZONE PENGZE COUNTY JIANGXI PROVINCE SDNF CHINA CHINA","customerAddress":"7-2-A2, HETERO CORPORATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726252200,"product":"D-MANDELIC ACID (ADC LIST SL.NO-512)","address":"7-2-A2, HETERO CORPORATE,","city":"HYDERABAD-A.P.","supplier":"JIANGXI KEYUAN BIOPHARM CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"HETERO DRUGS","customerCountry":"INDIA","quantity":"20000.00","actualQuantity":"20000","unit":"KGS","unitRateFc":"13.6","totalValueFC":"275613.2","currency":"USD","unitRateINR":"1154.8","date":"14-Sep-2024","totalValueINR":"23096725.78","totalValueInUsd":"275613.2","indian_port":"Madras Sea","hs_no":"29181990","bill_no":"5608913","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"JISHAN INDUSTRIAL ZONE PENGZE COUNTY JIANGXI PROVINCE SDNF CHINA","customerAddress":"7-2-A2, HETERO CORPORATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726425000,"product":"D(-)MANDELIC ACID (ADC SL NO 512) DATED 02.01.2012","address":"PLOT NO.174,PROGRESSIVE INDUSTRIAL","city":"TALUQ,MEDAK DIST.,A.P.","supplier":"JIANGXI KEYUAN BIOPHARM CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"HY-GRO CHEMICALS PHARMTEK","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"14","totalValueFC":"28350.4","currency":"USD","unitRateINR":"1187.9","date":"16-Sep-2024","totalValueINR":"2375800","totalValueInUsd":"28350.4","indian_port":"Madras Sea","hs_no":"29181990","bill_no":"5622527","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"JISHAN INDUSTRIAL ZONE PENGZE COUNTY JIANGXI PROVINCE SDNF CN","customerAddress":"PLOT NO.174,PROGRESSIVE INDUSTRIAL"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726770600,"product":"D(-)MANDELIC ACID (ADC SL NO 512) DATED 02.01.2012","address":"PLOT NO.174,PROGRESSIVE INDUSTRIAL","city":"TALUQ,MEDAK DIST.,A.P.","supplier":"N\/A","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"HY-GRO CHEMICALS PHARMTEK","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"14","totalValueFC":"28266.9","currency":"USD","unitRateINR":"1184.4","date":"20-Sep-2024","totalValueINR":"2368800","totalValueInUsd":"28266.9","indian_port":"Madras Sea","hs_no":"29181990","bill_no":"5707055","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"N\/A","customerAddress":"PLOT NO.174,PROGRESSIVE INDUSTRIAL"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726857000,"product":"SPECWHITE DL-MA (DL-MANDELIC ACID)","address":"6&20, 3RD FLOOR, A\/C MARKET","city":"MUMBAI","supplier":"SPEC CHEM INDUSTRY INC","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"INDCHEM INTERNATIONAL","customerCountry":"INDIA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"23","totalValueFC":"1200.3","currency":"USD","unitRateINR":"2011.8","date":"21-Sep-2024","totalValueINR":"100589.84","totalValueInUsd":"1200.3","indian_port":"JNPT","hs_no":"29181990","bill_no":"5738152","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"SHILIN INDUSTRIAL PARK, NO.10 WANSH OU ROAD, NANJING 211800 SDNF CHINA","customerAddress":"6&20, 3RD FLOOR, A\/C MARKET"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727289000,"product":"TEGO RENEWHA MANDELIC 25 KG (MANDELIC ACID)","address":"KRISLON HOUSE, SAKI VIHAR ROAD,","city":"MUMBAI, MAHARASHTRA.","supplier":"EVONIK","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"EVONIK","customerCountry":"INDIA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"68.3","totalValueFC":"15436.6","currency":"EUR","unitRateINR":"6468","date":"26-Sep-2024","totalValueINR":"1293602","totalValueInUsd":"15436.6","indian_port":"Bombay Air","hs_no":"29181990","bill_no":"5815544","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"ROOM 356, NO 2 TAI ZHONG NAN ROAD C HINA (SHANGHAI) PILOT FREE TRADE SH ANGHAI 200131 CN","customerAddress":"KRISLON HOUSE, SAKI VIHAR ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727548200,"product":"D-MANDELIC ACID","address":"BSEL TECH PARK,B-WING,10TH FLR,","city":"STATION,VASHI,NAVI MUMBAI ,MAHARASH","supplier":"JIANGXI KEYUAN BIOPHARM CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"WANBURY LIMITED","customerCountry":"INDIA","quantity":"11000.00","actualQuantity":"11000","unit":"KGS","unitRateFc":"14.5","totalValueFC":"161020.3","currency":"USD","unitRateINR":"1226.7","date":"29-Sep-2024","totalValueINR":"13493700","totalValueInUsd":"161020.3","indian_port":"Madras Sea","hs_no":"29181990","bill_no":"5866844","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"JISHANG INDUSTRIAL ZONE PENGZE COUNTRY JIANGXI PROVINCE SDNF CHINA","customerAddress":"BSEL TECH PARK,B-WING,10TH FLR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729017000,"product":"D-MANDELIC ACID","address":"BSEL TECH PARK,B-WING,10TH FLR,","city":"STATION,VASHI,NAVI MUMBAI ,MAHARASH","supplier":"BRILLIANT PHARMACEUTICAL LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"WANBURY LIMITED","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"17.7","totalValueFC":"35519.9","currency":"USD","unitRateINR":"1492.3","date":"16-Oct-2024","totalValueINR":"2984615","totalValueInUsd":"35519.9","indian_port":"Madras Sea","hs_no":"29181990","bill_no":"6151105","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"6\/F MANULIFE PLACE,348 KWUN TONG RD,KL,HONG KONG CHINA CHINA","customerAddress":"BSEL TECH PARK,B-WING,10TH FLR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729276200,"product":"TEGO RENEWHA MANDELIC (MANDELIC ACID)","address":"KRISLON HOUSE, SAKI VIHAR ROAD,","city":"MUMBAI, MAHARASHTRA.","supplier":"EVONIK INTERNATIONAL TRADING (SHANGHAI)","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"EVONIK","customerCountry":"INDIA","quantity":"350.00","actualQuantity":"350","unit":"KGS","unitRateFc":"68.5","totalValueFC":"26521.1","currency":"EUR","unitRateINR":"6367.1","date":"19-Oct-2024","totalValueINR":"2228476.25","totalValueInUsd":"26521.1","indian_port":"JNPT","hs_no":"29181990","bill_no":"6208839","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"CO.LTD. 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    02-Jan-2021
    29-Nov-2024
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    ABOUT THIS PAGE

    Mandelic Acid Manufacturers

    A Mandelic Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Mandelic Acid, including repackagers and relabelers. The FDA regulates Mandelic Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Mandelic Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Mandelic Acid manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Mandelic Acid Suppliers

    A Mandelic Acid supplier is an individual or a company that provides Mandelic Acid active pharmaceutical ingredient (API) or Mandelic Acid finished formulations upon request. The Mandelic Acid suppliers may include Mandelic Acid API manufacturers, exporters, distributors and traders.

    click here to find a list of Mandelic Acid suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Mandelic Acid GMP

    Mandelic Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Mandelic Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Mandelic Acid GMP manufacturer or Mandelic Acid GMP API supplier for your needs.

    Mandelic Acid CoA

    A Mandelic Acid CoA (Certificate of Analysis) is a formal document that attests to Mandelic Acid's compliance with Mandelic Acid specifications and serves as a tool for batch-level quality control.

    Mandelic Acid CoA mostly includes findings from lab analyses of a specific batch. For each Mandelic Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Mandelic Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (Mandelic Acid EP), Mandelic Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Mandelic Acid USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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