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Chemistry

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Also known as: 598-62-9, Manganese(ii) carbonate, Manganous carbonate, Rhodochrosite, Manganese carbonate (1:1), Carbonic acid, manganese salt
Molecular Formula
CMnO3
Molecular Weight
114.947  g/mol
InChI Key
XMWCXZJXESXBBY-UHFFFAOYSA-L
FDA UNII
9ZV57512ZM

Manganese Carbonate
1 2D Structure

Manganese Carbonate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
manganese(2+);carbonate
2.1.2 InChI
InChI=1S/CH2O3.Mn/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2
2.1.3 InChI Key
XMWCXZJXESXBBY-UHFFFAOYSA-L
2.1.4 Canonical SMILES
C(=O)([O-])[O-].[Mn+2]
2.2 Other Identifiers
2.2.1 UNII
9ZV57512ZM
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 598-62-9

2. Manganese(ii) Carbonate

3. Manganous Carbonate

4. Rhodochrosite

5. Manganese Carbonate (1:1)

6. Carbonic Acid, Manganese Salt

7. Manganese(2+) Carbonate

8. Manganese(2+);carbonate

9. Manganese Carbonate (mnco3)

10. 17375-37-0

11. Manganese(2+) Carbonate (1:1)

12. 9zv57512zm

13. Manganese(ii)carbonate

14. Carbonic Acid, Manganese(2+) Salt (1:1)

15. Natural Rhodochrosite

16. Mfcd00011116

17. Ccris 3660

18. Hsdb 790

19. Nsc-83512

20. Einecs 209-942-9

21. Nsc 83512

22. Unii-9zv57512zm

23. Einecs 241-414-3

24. Manganum Carbonicum

25. Ec 209-942-9

26. Rhodochrosite [inci]

27. Schembl32918

28. Dtxsid1042108

29. Manganese Carbonate [mi]

30. Manganese Carbonate [hsdb]

31. Manganum Carbonicum [hpus]

32. Carbonic Acid,manganese Salt

33. Manganese(ii) Carbonate, Mn 44%

34. Manganese Carbonate [who-dd]

35. Manganese(ii) Carbonate, Min. 90%

36. Akos015903237

37. Manganese(ii) Carbonate, P.a., 44%

38. Q414659

39. J-521674

40. Manganese(ii) Carbonate, 99.985% (metals Basis)

41. Manganese(ii) Carbonate, >=99.9% Trace Metals Basis

42. Manganese(ii) Carbonate Hydrate, 44-46% Mn Basis (kt)

43. 11-((5-dimethylaminonaphthalene-1-sulfonyl) Amino)undecanoic

2.4 Create Date
2005-07-19
3 Chemical and Physical Properties
Molecular Weight 114.947 g/mol
Molecular Formula CMnO3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass114.922787 g/mol
Monoisotopic Mass114.922787 g/mol
Topological Polar Surface Area63.2 Ų
Heavy Atom Count5
Formal Charge0
Complexity18.8
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Therapeutic Uses

MANGANESE CARBONATE IS USED IN MEDICINE AS A HEMATINIC

Venugopal, B. and T.D. Luckey. Metal Toxicity in Mammals, 2. New York: Plenum Press, 1978., p. 263


5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Pharmacological Classes
Paramagnetic Contrast Agent [EPC]; Magnetic Resonance Contrast Activity [MoA]
5.2 Absorption, Distribution and Excretion

The subcellular distribution of manganese (Mn) in brains of mice chronically admin Mn in different chemical forms with food was examined using gel chromatography. Male ddY-mice were divided into five groups of six animals each, & Groups 1 to 4 were given 2 grams/kilogram Mn of standard laboratory mouse chow) in the form of manganese chloride (MnCl2), manganese acetate (MnAc), manganese carbonate (MnCO3), or manganese oxide (MnO2), in the diets for 12 months, while Group 5 served as control. 24 hr after the last feed, animals were decapitated & brains were rapidly removed for study of the different regions (corpus striatum (CS), hypothalamus, midbrain, cerebral cortex (CC), hippocampus, cerebellum, & medulla oblongata). Subcellular fractions (mitochondrial, microsomal & cytosolic) & gel chromatography fractions were analyzed for Mn contents using flame atomizer absorption spectrophotometry. Results showed that CC levels of Mn in mice exposed to the nearly insoluble MnCO3 & MnO2 were higher than in controls, while Mn concns in the CS were similar to those in controls. Microsomal Mn in treated mice was also higher than in controls. The gel chromatographic profile of CS showed that 20% Mn was in the high molecular weight (MW) fractions, 45% was in the middle MW fractions, while 32% was in the low MW fractions. The % Mn in high MW fractions was higher (29% to 49%) in the Mn treated groups, than in controls. The % of Mn in low MW fractions of the MnO2 exposed group (9%) was lower than in the MnCl2, MnAc, & MnCO3 exposed groups (42%, 36%, & 38%, respectively). The authors conclude that the brain regional distribution of Mn from the virtually insoluble cmpds is different from that of soluble Mn cmpds, & that striatal subcellular & gel chromatographic profiles are similar for the divalent Mn cmpds. They add that there is more Mn associated with fast migrating ligands in the striatal cytosol of the Mn treated groups than in the controls, & that these binding characteristics are different from those of other organs.

PMID:8475509 Komura J et al.; Toxicology Letters 66 (3): 287-294 (1993)


ABOUT THIS PAGE

Manganese Carbonate Manufacturers

A Manganese Carbonate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Manganese Carbonate, including repackagers and relabelers. The FDA regulates Manganese Carbonate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Manganese Carbonate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Manganese Carbonate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Manganese Carbonate Suppliers

A Manganese Carbonate supplier is an individual or a company that provides Manganese Carbonate active pharmaceutical ingredient (API) or Manganese Carbonate finished formulations upon request. The Manganese Carbonate suppliers may include Manganese Carbonate API manufacturers, exporters, distributors and traders.

click here to find a list of Manganese Carbonate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Manganese Carbonate GMP

Manganese Carbonate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Manganese Carbonate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Manganese Carbonate GMP manufacturer or Manganese Carbonate GMP API supplier for your needs.

Manganese Carbonate CoA

A Manganese Carbonate CoA (Certificate of Analysis) is a formal document that attests to Manganese Carbonate's compliance with Manganese Carbonate specifications and serves as a tool for batch-level quality control.

Manganese Carbonate CoA mostly includes findings from lab analyses of a specific batch. For each Manganese Carbonate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Manganese Carbonate may be tested according to a variety of international standards, such as European Pharmacopoeia (Manganese Carbonate EP), Manganese Carbonate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Manganese Carbonate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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