Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

DEVELOPMENTS

2 Drugs in Development

2 Drugs in Development

DIGITAL CONTENT

1 NEWS #PharmaBuzz

media
1 NEWS #PharmaBuzz

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

2DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Suvn-502, Masupirdine, 701205-60-9, Masupirdine (free base), 8xz281ao3g, 701205-60-9 (free base).

Molecular Formula

C₂₁H₂₄BrN₃O₃S

Molecular Weight

478.4 g/mol

InChI Key

GWCYPEHWIZXYFZ-UHFFFAOYSA-N

FDA UNII

8XZ281AO3G

SUVN-502 is a novel, potent, safe, highly selective and orally active antagonist at a central nervous system serotonin receptor site 5-HT6 intended for treatment of cognitive disorders such as Alzheimers and Schizophrenia, an unmet medical need.

1 2D Structure

Masupirdine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-(2-bromophenyl)sulfonyl-5-methoxy-3-[(4-methylpiperazin-1-yl)methyl]indole

2.1.2 InChI

InChI=1S/C21H24BrN3O3S/c1-23-9-11-24(12-10-23)14-16-15-25(20-8-7-17(28-2)13-18(16)20)29(26,27)21-6-4-3-5-19(21)22/h3-8,13,15H,9-12,14H2,1-2H3

2.1.3 InChI Key

GWCYPEHWIZXYFZ-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN1CCN(CC1)CC2=CN(C3=C2C=C(C=C3)OC)S(=O)(=O)C4=CC=CC=C4Br

2.2 Other Identifiers

2.2.1 UNII

8XZ281AO3G

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 1-((2-bromophenyl)sulfonyl)-5-methoxy-3-((4-methyl-1-piperazinyl)methyl)-1h-indole Dimesylate Monohydrate

2. Suvn-502

2.3.2 Depositor-Supplied Synonyms

1. Suvn-502

2. Masupirdine

3. 701205-60-9

4. Masupirdine (free Base)

5. 8xz281ao3g

6. 701205-60-9 (free Base).

7. Masupirdin

8. Masupirdine [inn]

9. Unii-8xz281ao3g

10. Schembl946320

11. Chembl4117187

12. Us11116764, Compound 1

13. Bdbm518688

14. 1-(2-bromophenyl)sulfonyl-5-methoxy-3-[(4-methylpiperazin-1-yl)methyl]indole

15. Db06140

16. Hy-109118

17. Cs-0078331

2.4 Create Date

2006-10-25

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₂₄BrN₃O₃S
Molecular Weight	478.4 g/mol
XLogP3	3.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	477.07218 g/mol
Monoisotopic Mass	477.07218 g/mol
Topological Polar Surface Area	63.2 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	650
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Indication

Investigated for use/treatment in neurologic disorders.

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Serotonin Antagonists

Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS. (See all compounds classified as Serotonin Antagonists.)

Drugs in Development