Find Masupirdine manufacturers, exporters & distributors on PharmaCompass

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ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: Suvn-502, Masupirdine, 701205-60-9, Masupirdine (free base), 8xz281ao3g, 701205-60-9 (free base).
Molecular Formula
C21H24BrN3O3S
Molecular Weight
478.4  g/mol
InChI Key
GWCYPEHWIZXYFZ-UHFFFAOYSA-N
FDA UNII
8XZ281AO3G

Masupirdine
SUVN-502 is a novel, potent, safe, highly selective and orally active antagonist at a central nervous system serotonin receptor site 5-HT6 intended for treatment of cognitive disorders such as Alzheimers and Schizophrenia, an unmet medical need.
1 2D Structure

Masupirdine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-(2-bromophenyl)sulfonyl-5-methoxy-3-[(4-methylpiperazin-1-yl)methyl]indole
2.1.2 InChI
InChI=1S/C21H24BrN3O3S/c1-23-9-11-24(12-10-23)14-16-15-25(20-8-7-17(28-2)13-18(16)20)29(26,27)21-6-4-3-5-19(21)22/h3-8,13,15H,9-12,14H2,1-2H3
2.1.3 InChI Key
GWCYPEHWIZXYFZ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1CCN(CC1)CC2=CN(C3=C2C=C(C=C3)OC)S(=O)(=O)C4=CC=CC=C4Br
2.2 Other Identifiers
2.2.1 UNII
8XZ281AO3G
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1-((2-bromophenyl)sulfonyl)-5-methoxy-3-((4-methyl-1-piperazinyl)methyl)-1h-indole Dimesylate Monohydrate

2. Suvn-502

2.3.2 Depositor-Supplied Synonyms

1. Suvn-502

2. Masupirdine

3. 701205-60-9

4. Masupirdine (free Base)

5. 8xz281ao3g

6. 701205-60-9 (free Base).

7. Masupirdin

8. Masupirdine [inn]

9. Unii-8xz281ao3g

10. Schembl946320

11. Chembl4117187

12. Us11116764, Compound 1

13. Bdbm518688

14. 1-(2-bromophenyl)sulfonyl-5-methoxy-3-[(4-methylpiperazin-1-yl)methyl]indole

15. Db06140

16. Hy-109118

17. Cs-0078331

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 478.4 g/mol
Molecular Formula C21H24BrN3O3S
XLogP33.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass477.07218 g/mol
Monoisotopic Mass477.07218 g/mol
Topological Polar Surface Area63.2 Ų
Heavy Atom Count29
Formal Charge0
Complexity650
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Investigated for use/treatment in neurologic disorders.


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Serotonin Antagonists

Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS. (See all compounds classified as Serotonin Antagonists.)


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ABOUT THIS PAGE

Masupirdine Manufacturers

A Masupirdine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Masupirdine, including repackagers and relabelers. The FDA regulates Masupirdine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Masupirdine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Masupirdine Suppliers

A Masupirdine supplier is an individual or a company that provides Masupirdine active pharmaceutical ingredient (API) or Masupirdine finished formulations upon request. The Masupirdine suppliers may include Masupirdine API manufacturers, exporters, distributors and traders.

Masupirdine GMP

Masupirdine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Masupirdine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Masupirdine GMP manufacturer or Masupirdine GMP API supplier for your needs.

Masupirdine CoA

A Masupirdine CoA (Certificate of Analysis) is a formal document that attests to Masupirdine's compliance with Masupirdine specifications and serves as a tool for batch-level quality control.

Masupirdine CoA mostly includes findings from lab analyses of a specific batch. For each Masupirdine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Masupirdine may be tested according to a variety of international standards, such as European Pharmacopoeia (Masupirdine EP), Masupirdine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Masupirdine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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